LeishMANIAdb
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BolA family transcriptional regulator

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
BolA family transcriptional regulator
Gene product:
BolA-like protein, putative
Species:
Leishmania mexicana
UniProt:
E9AVI2_LEIMU
TriTrypDb:
LmxM.21.1855
Length:
79

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 7
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AVI2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVI2

Putative motif mimicry

Leishmania From To Domain/Motif Score
LIG_14-3-3_CanoR_1 36 45 PF00244 0.502
LIG_BRCT_BRCA1_1 38 42 PF00533 0.447
LIG_IRF3_LxIS_1 67 73 PF10401 0.504
LIG_LIR_Nem_3 14 19 PF02991 0.398
LIG_LIR_Nem_3 39 45 PF02991 0.461
LIG_PTB_Apo_2 52 59 PF02174 0.447
LIG_SUMO_SIM_par_1 17 22 PF11976 0.460
LIG_TRAF2_1 27 30 PF00917 0.409
MOD_CK2_1 24 30 PF00069 0.513
MOD_GlcNHglycan 25 29 PF01048 0.292
MOD_GlcNHglycan 38 41 PF01048 0.176
MOD_GlcNHglycan 63 66 PF01048 0.264
MOD_GlcNHglycan 72 75 PF01048 0.264
MOD_NEK2_1 70 75 PF00069 0.464
MOD_Plk_4 4 10 PF00069 0.479
TRG_DiLeu_BaLyEn_6 43 48 PF01217 0.464
TRG_ER_diArg_1 50 53 PF00400 0.454

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IGJ1 Leptomonas seymouri 83% 100%
A0A0S4IQU1 Bodo saltans 49% 92%
A0A3Q8IAI7 Leishmania donovani 94% 100%
A4HZJ2 Leishmania infantum 94% 100%
D0A0Z4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 53% 71%
E9AIV4 Leishmania braziliensis 81% 100%
P29943 Sinorhizobium sp. 39% 85%
Q4QBZ7 Leishmania major 95% 100%
Q86KD0 Dictyostelium discoideum 32% 69%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS