Proteasome subunit alpha type

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

proteasome alpha 2 subunit, putative

Species:

Leishmania mexicana

UniProt:

E9AVG6_LEIMU

TriTrypDb:

LmxM.21.1700

Length:

231

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0005737	cytoplasm	2	12
GO:0019773	proteasome core complex, alpha-subunit complex	2	12
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:0005839	proteasome core complex	3	1
GO:0140535	intracellular protein-containing complex	2	1
GO:1902494	catalytic complex	2	1

Expansion

Sequence features

E9AVG6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVG6

PDB structure(s): 6qm7_B , 6qm7_P , 6qm8_B , 6qm8_P , 6tcz_b , 6td5_b

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	12
GO:0006511	ubiquitin-dependent protein catabolic process	7	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009056	catabolic process	2	12
GO:0009057	macromolecule catabolic process	4	12
GO:0009987	cellular process	1	12
GO:0019538	protein metabolic process	3	12
GO:0019941	modification-dependent protein catabolic process	6	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043632	modification-dependent macromolecule catabolic process	5	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044248	cellular catabolic process	3	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0044265	obsolete cellular macromolecule catabolic process	4	12
GO:0051603	proteolysis involved in protein catabolic process	5	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:1901575	organic substance catabolic process	3	12
GO:0010498	proteasomal protein catabolic process	5	1
GO:0030163	protein catabolic process	4	1
GO:1901565	organonitrogen compound catabolic process	4	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0016787	hydrolase activity	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	53	57	PF00656	0.589
CLV_NRD_NRD_1	109	111	PF00675	0.376
CLV_NRD_NRD_1	88	90	PF00675	0.283
CLV_PCSK_KEX2_1	174	176	PF00082	0.303
CLV_PCSK_PC1ET2_1	174	176	PF00082	0.303
CLV_PCSK_SKI1_1	169	173	PF00082	0.303
DOC_MAPK_gen_1	174	182	PF00069	0.514
DOC_SPAK_OSR1_1	215	219	PF12202	0.492
DOC_WW_Pin1_4	162	167	PF00397	0.557
DOC_WW_Pin1_4	9	14	PF00397	0.503
LIG_14-3-3_CanoR_1	110	119	PF00244	0.555
LIG_14-3-3_CanoR_1	175	179	PF00244	0.564
LIG_14-3-3_CanoR_1	96	102	PF00244	0.452
LIG_Actin_WH2_2	179	196	PF00022	0.503
LIG_BIR_II_1	1	5	PF00653	0.527
LIG_BIR_III_4	138	142	PF00653	0.589
LIG_BRCT_BRCA1_1	1	5	PF00533	0.629
LIG_BRCT_BRCA1_1	149	153	PF00533	0.493
LIG_Clathr_ClatBox_1	17	21	PF01394	0.503
LIG_FHA_1	186	192	PF00498	0.503
LIG_FHA_1	37	43	PF00498	0.484
LIG_FHA_2	190	196	PF00498	0.503
LIG_FHA_2	51	57	PF00498	0.589
LIG_LIR_Nem_3	113	119	PF02991	0.504
LIG_LIR_Nem_3	2	8	PF02991	0.596
LIG_PCNA_yPIPBox_3	205	215	PF02747	0.591
LIG_PDZ_Class_3	226	231	PF00595	0.435
LIG_SH2_STAP1	176	180	PF00017	0.503
LIG_SH2_STAP1	22	26	PF00017	0.503
LIG_SH2_STAT3	227	230	PF00017	0.429
LIG_SH2_STAT3	91	94	PF00017	0.400
LIG_SH2_STAT5	176	179	PF00017	0.514
LIG_SH2_STAT5	227	230	PF00017	0.429
LIG_SH2_STAT5	91	94	PF00017	0.518
LIG_SUMO_SIM_par_1	188	195	PF11976	0.503
LIG_SUMO_SIM_par_1	217	222	PF11976	0.502
LIG_UBA3_1	190	194	PF00899	0.503
LIG_WRC_WIRS_1	8	13	PF05994	0.503
MOD_CDK_SPxxK_3	162	169	PF00069	0.580
MOD_CDK_SPxxK_3	9	16	PF00069	0.503
MOD_CK1_1	203	209	PF00069	0.551
MOD_CK2_1	189	195	PF00069	0.511
MOD_GlcNHglycan	112	115	PF01048	0.328
MOD_GlcNHglycan	121	124	PF01048	0.256
MOD_GlcNHglycan	13	16	PF01048	0.314
MOD_GlcNHglycan	148	152	PF01048	0.312
MOD_GlcNHglycan	74	77	PF01048	0.302
MOD_GSK3_1	156	163	PF00069	0.517
MOD_GSK3_1	185	192	PF00069	0.503
MOD_GSK3_1	199	206	PF00069	0.503
MOD_GSK3_1	7	14	PF00069	0.367
MOD_NEK2_1	119	124	PF00069	0.514
MOD_NEK2_1	128	133	PF00069	0.514
MOD_NEK2_2	189	194	PF00069	0.503
MOD_PIKK_1	103	109	PF00454	0.511
MOD_PIKK_1	117	123	PF00454	0.482
MOD_PIKK_1	203	209	PF00454	0.487
MOD_PKA_1	110	116	PF00069	0.608
MOD_PKA_1	174	180	PF00069	0.503
MOD_PKA_2	174	180	PF00069	0.503
MOD_Plk_1	203	209	PF00069	0.487
MOD_Plk_1	55	61	PF00069	0.559
MOD_Plk_2-3	217	223	PF00069	0.453
MOD_Plk_4	128	134	PF00069	0.539
MOD_Plk_4	149	155	PF00069	0.503
MOD_Plk_4	50	56	PF00069	0.589
MOD_ProDKin_1	162	168	PF00069	0.557
MOD_ProDKin_1	9	15	PF00069	0.503
MOD_SUMO_rev_2	165	171	PF00179	0.528
TRG_ENDOCYTIC_2	116	119	PF00928	0.528
TRG_ENDOCYTIC_2	74	77	PF00928	0.497
TRG_ENDOCYTIC_2	95	98	PF00928	0.592
TRG_NLS_MonoExtC_3	46	51	PF00514	0.580
TRG_Pf-PMV_PEXEL_1	82	86	PF00026	0.303

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2I1	Leptomonas seymouri	41%	95%
A0A0N0P4E6	Leptomonas seymouri	32%	97%
A0A0N0P7F8	Leptomonas seymouri	25%	76%
A0A0N1HVL0	Leptomonas seymouri	24%	91%
A0A0N1I173	Leptomonas seymouri	93%	100%
A0A0N1I278	Leptomonas seymouri	39%	94%
A0A0N1I2E0	Leptomonas seymouri	29%	92%
A0A0N1ILS9	Leptomonas seymouri	42%	87%
A0A0N1PBJ3	Leptomonas seymouri	39%	81%
A0A0S4INC9	Bodo saltans	31%	98%
A0A0S4IQU5	Bodo saltans	38%	87%
A0A0S4IU58	Bodo saltans	74%	100%
A0A0S4IWG0	Bodo saltans	37%	86%
A0A0S4IX63	Bodo saltans	27%	79%
A0A0S4J6W0	Bodo saltans	27%	92%
A0A0S4JLA2	Bodo saltans	35%	82%
A0A1X0NHF3	Trypanosomatidae	79%	100%
A0A1X0NJ65	Trypanosomatidae	41%	94%
A0A1X0NMF1	Trypanosomatidae	34%	97%
A0A1X0NNS5	Trypanosomatidae	35%	81%
A0A1X0NVU4	Trypanosomatidae	38%	94%
A0A1X0P5G1	Trypanosomatidae	23%	90%
A0A1X0P5Y6	Trypanosomatidae	26%	92%
A0A1X0P7U3	Trypanosomatidae	27%	74%
A0A1X0P853	Trypanosomatidae	41%	87%
A0A3Q8IB07	Leishmania donovani	97%	100%
A0A3Q8IC41	Leishmania donovani	42%	95%
A0A3Q8IFZ3	Leishmania donovani	40%	88%
A0A3Q8IIY4	Leishmania donovani	25%	76%
A0A3R7KUN3	Trypanosoma rangeli	35%	81%
A0A3R7LAV3	Trypanosoma rangeli	39%	94%
A0A3R7MIT1	Trypanosoma rangeli	39%	87%
A0A3R7MZI3	Trypanosoma rangeli	28%	74%
A0A3S5H6I0	Leishmania donovani	41%	94%
A0A3S5H7H2	Leishmania donovani	32%	97%
A0A3S5IS75	Trypanosoma rangeli	34%	97%
A0A3S7WST4	Leishmania donovani	37%	81%
A0A422N1Q5	Trypanosoma rangeli	24%	91%
A0A422N8R3	Trypanosoma rangeli	42%	94%
A0A422N8U2	Trypanosoma rangeli	79%	100%
A0A422P146	Trypanosoma rangeli	28%	92%
A0A6L0XSJ0	Leishmania infantum	30%	92%
A0B5B1	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	28%	100%
A0RXV1	Cenarchaeum symbiosum (strain A)	33%	100%
A1RSJ8	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	31%	100%
A1RTI7	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	35%	100%
A1RWY6	Thermofilum pendens (strain DSM 2475 / Hrk 5)	30%	100%
A1RX71	Thermofilum pendens (strain DSM 2475 / Hrk 5)	31%	100%
A1XQU1	Sus scrofa	25%	83%
A2BN24	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	26%	100%
A2BN27	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	26%	100%
A2SS78	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	25%	100%
A2Y9X7	Oryza sativa subsp. indica	43%	92%
A2YVR7	Oryza sativa subsp. indica	58%	98%
A2YXU2	Oryza sativa subsp. indica	44%	93%
A2Z3I9	Oryza sativa subsp. indica	46%	93%
A3CUS9	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	24%	100%
A3CW55	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	37%	96%
A3DN21	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	28%	100%
A3DN27	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	31%	100%
A3MS44	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	35%	100%
A3MXQ6	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	29%	100%
A4FZT6	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	42%	89%
A4H7J0	Leishmania braziliensis	38%	100%
A4H9T4	Leishmania braziliensis	39%	75%
A4HC34	Leishmania braziliensis	94%	100%
A4HFD7	Leishmania braziliensis	32%	100%
A4HLC5	Leishmania braziliensis	41%	100%
A4HN55	Leishmania braziliensis	23%	100%
A4HNE9	Leishmania braziliensis	30%	100%
A4HP20	Leishmania braziliensis	41%	100%
A4HP29	Leishmania braziliensis	25%	76%
A4HUT6	Leishmania infantum	41%	94%
A4HVX3	Leishmania infantum	37%	81%
A4HZI9	Leishmania infantum	42%	95%
A4I357	Leishmania infantum	32%	97%
A4IDD0	Leishmania infantum	42%	88%
A4IDD6	Leishmania infantum	25%	76%
A4WH05	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	32%	100%
A4WMZ0	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	33%	100%
A4YCU9	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	43%	96%
A4YJ04	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	25%	100%
A5UJS2	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	38%	92%
A5UM14	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	25%	100%
A6URN9	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	38%	89%
A6UT20	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	27%	100%
A6VIP0	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	41%	89%
A6VK02	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	24%	100%
A7I841	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	26%	100%
A7I9C7	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	40%	96%
A8AA46	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	28%	100%
A8AB58	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	28%	100%
A8M8R5	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	25%	100%
A8MBW0	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	29%	100%
A9A2U7	Nitrosopumilus maritimus (strain SCM1)	33%	100%
A9A788	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	24%	100%
A9A846	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	41%	89%
B0R2T2	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	38%	91%
B0R4C8	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	26%	95%
B1L6S7	Korarchaeum cryptofilum (strain OPF8)	33%	100%
B1L6X8	Korarchaeum cryptofilum (strain OPF8)	27%	100%
B1YA36	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	33%	100%
B1YDJ0	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	29%	100%
B6YSH9	Thermococcus onnurineus (strain NA1)	42%	89%
B6YSW2	Thermococcus onnurineus (strain NA1)	31%	100%
B6YXV3	Thermococcus onnurineus (strain NA1)	25%	100%
B8D673	Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n)	27%	100%
B8D683	Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n)	31%	100%
B8GEZ3	Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)	36%	96%
B8GG66	Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)	27%	100%
B9LTS6	Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)	26%	95%
C3MQ16	Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)	27%	100%
C3MQ43	Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)	43%	96%
C3MRE5	Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)	25%	100%
C3MVD5	Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)	27%	100%
C3MVG1	Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)	43%	96%
C3MY41	Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)	25%	100%
C3MZI0	Sulfolobus islandicus (strain M.16.27)	25%	100%
C3N5N4	Sulfolobus islandicus (strain M.16.27)	27%	100%
C3N5R0	Sulfolobus islandicus (strain M.16.27)	43%	96%
C3N7K2	Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)	25%	100%
C3NE98	Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)	27%	100%
C3NEC6	Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)	43%	96%
C3NFX2	Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)	25%	100%
C3NHC6	Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)	43%	96%
C3NHF1	Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)	27%	100%
C4KHB0	Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)	27%	100%
C4KHD9	Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)	43%	96%
C4KIR0	Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)	25%	100%
C5A2C2	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	42%	89%
C5A2D5	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	28%	100%
C5A7L1	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	28%	100%
C6A2V9	Thermococcus sibiricus (strain DSM 12597 / MM 739)	25%	100%
C6A3R1	Thermococcus sibiricus (strain DSM 12597 / MM 739)	27%	100%
C6A459	Thermococcus sibiricus (strain DSM 12597 / MM 739)	42%	89%
C7P6N4	Methanocaldococcus fervens (strain DSM 4213 / JCM 15782 / AG86)	28%	100%
C9REN7	Methanocaldococcus vulcanius (strain ATCC 700851 / DSM 12094 / M7)	27%	100%
C9ZKV8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	97%
C9ZT49	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	81%
C9ZYH8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	92%
D0A0Z1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	94%
D0A0Z7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	78%	87%
D0A305	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	87%
D0A312	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	75%
D0A7M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	94%
D0KRX1	Saccharolobus solfataricus (strain 98/2)	25%	100%
D0KTH0	Saccharolobus solfataricus (strain 98/2)	25%	100%
D1Z199	Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE)	30%	100%
D2PDG6	Sulfolobus islandicus (strain L.D.8.5 / Lassen #2)	25%	100%
D2PK63	Sulfolobus islandicus (strain L.D.8.5 / Lassen #2)	27%	100%
D2RGT4	Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)	29%	100%
D2RQX3	Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB 13204 / VKM B-1734 / 4k)	29%	95%
D2RUI0	Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / JCM 9101 / NCIMB 13204 / VKM B-1734 / 4k)	28%	97%
D3E0A3	Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1)	26%	100%
D3RX66	Ferroglobus placidus (strain DSM 10642 / AEDII12DO)	27%	100%
D3S8M7	Methanocaldococcus sp. (strain FS406-22)	27%	100%
D3SSQ6	Natrialba magadii (strain ATCC 43099 / DSM 3394 / CCM 3739 / CIP 104546 / IAM 13178 / JCM 8861 / NBRC 102185 / NCIMB 2190 / MS3)	27%	95%
D4GYZ1	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	28%	95%
D5EAS6	Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP)	31%	100%
E9ACZ6	Leishmania major	32%	100%
E9AFW0	Leishmania major	28%	100%
E9ANH0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9APM4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9AST1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9AST7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	76%
E9AVH9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	95%
E9AYS1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	97%
E9B713	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	92%
F4JJE5	Arabidopsis thaliana	30%	100%
O13268	Gallus gallus	43%	93%
O14250	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	85%
O14818	Homo sapiens	44%	93%
O16811	Drosophila virilis	42%	94%
O16812	Drosophila virilis	36%	94%
O17586	Caenorhabditis elegans	32%	94%
O23708	Arabidopsis thaliana	58%	98%
O23712	Arabidopsis thaliana	36%	83%
O23715	Arabidopsis thaliana	31%	93%
O23717	Arabidopsis thaliana	26%	84%
O24030	Solanum lycopersicum	47%	89%
O24361	Spinacia oleracea	26%	85%
O24362	Spinacia oleracea	32%	93%
O24616	Arabidopsis thaliana	48%	92%
O24733	Thermococcus sp. (strain JCM 11816 / KS-1)	43%	89%
O26782	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	41%	93%
O27270	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	31%	100%
O29760	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	42%	94%
O35955	Mus musculus	30%	85%
O42265	Gallus gallus	35%	89%
O44156	Caenorhabditis elegans	33%	89%
O48551	Glycine max	33%	94%
O50110	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	26%	100%
O55234	Mus musculus	25%	88%
O57983	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	25%	100%
O59219	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	43%	89%
O59770	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	91%
O70435	Mus musculus	33%	91%
O73672	Carassius auratus	56%	99%
O81146	Arabidopsis thaliana	33%	94%
O81147	Arabidopsis thaliana	32%	94%
O81148	Arabidopsis thaliana	42%	92%
O81149	Arabidopsis thaliana	41%	97%
O82530	Petunia hybrida	40%	93%
O94517	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	95%
O94579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	54%	94%
O96788	Trypanosoma brucei rhodesiense	39%	87%
P0C8Y9	Oryza sativa subsp. indica	42%	92%
P0DKK3	Oryza sativa subsp. japonica	43%	92%
P0DKK4	Oryza sativa subsp. japonica	43%	92%
P12881	Drosophila melanogaster	40%	83%
P17220	Rattus norvegicus	55%	99%
P18053	Drosophila melanogaster	38%	88%
P18420	Rattus norvegicus	33%	88%
P18422	Rattus norvegicus	33%	91%
P21242	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	80%
P21243	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	92%
P21670	Rattus norvegicus	40%	89%
P22769	Drosophila melanogaster	37%	93%
P23638	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	90%
P23639	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	49%	92%
P24495	Xenopus laevis	56%	99%
P25043	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	89%
P25156	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	37%	99%
P25786	Homo sapiens	35%	88%
P25787	Homo sapiens	55%	99%
P25788	Homo sapiens	33%	91%
P25789	Homo sapiens	40%	89%
P28061	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	25%	100%
P28062	Homo sapiens	27%	84%
P28063	Mus musculus	27%	84%
P28064	Rattus norvegicus	27%	84%
P28066	Homo sapiens	36%	96%
P28074	Homo sapiens	25%	88%
P28075	Rattus norvegicus	24%	88%
P30186	Arabidopsis thaliana	41%	92%
P30655	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	85%
P32379	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	89%
P34064	Rattus norvegicus	35%	96%
P34065	Gallus gallus	27%	90%
P34066	Arabidopsis thaliana	36%	83%
P34119	Dictyostelium discoideum	44%	92%
P34120	Dictyostelium discoideum	41%	92%
P40301	Drosophila melanogaster	54%	99%
P40302	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	99%
P40303	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	91%
P40306	Homo sapiens	29%	85%
P48004	Rattus norvegicus	44%	91%
P49722	Mus musculus	55%	99%
P52427	Spinacia oleracea	44%	92%
P52428	Oryza sativa subsp. japonica	36%	86%
P57697	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	38%	91%
P60900	Homo sapiens	32%	94%
P60901	Rattus norvegicus	32%	94%
P70195	Mus musculus	25%	83%
P90513	Acanthamoeba castellanii	36%	92%
P92188	Trypanosoma cruzi	39%	87%
Q09583	Caenorhabditis elegans	28%	92%
Q09682	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	93%
Q09841	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	87%
Q0J006	Oryza sativa subsp. japonica	46%	93%
Q0W2D6	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	25%	100%
Q10329	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	89%
Q10KF0	Oryza sativa subsp. japonica	58%	98%
Q12YV7	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	29%	100%
Q18GX3	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	29%	95%
Q18K08	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	38%	92%
Q24178	Drosophila melanogaster	38%	93%
Q27488	Caenorhabditis elegans	51%	100%
Q27562	Dictyostelium discoideum	37%	93%
Q27563	Dictyostelium discoideum	37%	93%
Q27575	Drosophila melanogaster	39%	92%
Q2FQL8	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	30%	100%
Q2NI68	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	28%	100%
Q2TBP0	Bos taurus	25%	83%
Q2YDE4	Bos taurus	32%	94%
Q32KL2	Bos taurus	25%	88%
Q3IPJ1	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	35%	91%
Q3IPX1	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	29%	97%
Q3T0T1	Bos taurus	28%	85%
Q3T0X5	Bos taurus	35%	88%
Q3T0Y5	Bos taurus	55%	99%
Q3T112	Bos taurus	27%	84%
Q3ZBG0	Bos taurus	44%	93%
Q3ZCK9	Bos taurus	40%	89%
Q42134	Arabidopsis thaliana	41%	97%
Q469M6	Methanosarcina barkeri (strain Fusaro / DSM 804)	41%	93%
Q46G14	Methanosarcina barkeri (strain Fusaro / DSM 804)	31%	100%
Q4JAA8	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	30%	100%
Q4JAY3	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	28%	100%
Q4JB24	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	41%	95%
Q4KM35	Rattus norvegicus	29%	85%
Q4Q1Q9	Leishmania major	25%	76%
Q4Q1R5	Leishmania major	42%	100%
Q4QC00	Leishmania major	42%	100%
Q4QC13	Leishmania major	97%	100%
Q4QFV4	Leishmania major	37%	100%
Q4QH56	Leishmania major	41%	100%
Q4R3H2	Macaca fascicularis	35%	88%
Q4R7D9	Macaca fascicularis	44%	92%
Q4R932	Macaca fascicularis	40%	89%
Q54DM7	Dictyostelium discoideum	56%	100%
Q54XM7	Dictyostelium discoideum	31%	92%
Q55G04	Dictyostelium discoideum	37%	96%
Q58634	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	28%	100%
Q58DU5	Bos taurus	33%	91%
Q59565	Methanosarcina thermophila	40%	94%
Q5E987	Bos taurus	36%	96%
Q5JDJ9	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	30%	100%
Q5JHL8	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	25%	100%
Q5JIU9	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	43%	89%
Q5R8S2	Pongo abelii	25%	88%
Q5RDH8	Pongo abelii	44%	93%
Q5REN2	Pongo abelii	35%	88%
Q5V1D4	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	41%	95%
Q5V1D5	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	28%	100%
Q5V2X8	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	39%	89%
Q5VRG3	Oryza sativa subsp. japonica	42%	92%
Q5W416	Canis lupus familiaris	26%	84%
Q60177	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	46%	89%
Q6L0W3	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	37%	99%
Q6L181	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	24%	100%
Q6LZD4	Methanococcus maripaludis (strain S2 / LL)	27%	100%
Q6M0L9	Methanococcus maripaludis (strain S2 / LL)	41%	89%
Q6YT00	Oryza sativa subsp. japonica	44%	93%
Q8L4A7	Arabidopsis thaliana	58%	98%
Q8PTU1	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	40%	93%
Q8PZ04	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	28%	100%
Q8SQN7	Encephalitozoon cuniculi (strain GB-M1)	28%	100%
Q8SQP9	Encephalitozoon cuniculi (strain GB-M1)	26%	95%
Q8SQS5	Encephalitozoon cuniculi (strain GB-M1)	25%	100%
Q8SRU3	Encephalitozoon cuniculi (strain GB-M1)	32%	100%
Q8SRU7	Encephalitozoon cuniculi (strain GB-M1)	28%	100%
Q8TAA3	Homo sapiens	42%	90%
Q8TJB5	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	27%	100%
Q8TPX5	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	41%	94%
Q8TW10	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	31%	100%
Q8TYB7	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	41%	94%
Q8U0L6	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	44%	89%
Q8U4C9	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	26%	100%
Q8X077	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	93%
Q8ZST5	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	32%	100%
Q8ZVM1	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	46%	95%
Q8ZYF2	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	36%	100%
Q94561	Entamoeba histolytica	38%	94%
Q95005	Caenorhabditis elegans	39%	91%
Q95008	Caenorhabditis elegans	35%	93%
Q95083	Drosophila melanogaster	36%	95%
Q975D1	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	29%	100%
Q975G5	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	43%	95%
Q975U8	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	28%	100%
Q97AZ7	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	25%	100%
Q97BZ8	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	37%	99%
Q980L4	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	25%	100%
Q99436	Homo sapiens	23%	83%
Q9CWH6	Mus musculus	45%	92%
Q9GNZ8	Leishmania infantum	97%	100%
Q9GU37	Trypanosoma brucei brucei	27%	87%
Q9HR36	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	26%	95%
Q9JHW0	Rattus norvegicus	25%	83%
Q9LIP2	Arabidopsis thaliana	26%	85%
Q9LST6	Oryza sativa subsp. japonica	31%	100%
Q9LSU0	Oryza sativa subsp. japonica	32%	93%
Q9LSU1	Oryza sativa subsp. japonica	42%	97%
Q9LSU3	Oryza sativa subsp. japonica	30%	94%
Q9M4T8	Glycine max	41%	97%
Q9N599	Caenorhabditis elegans	40%	92%
Q9NDA2	Trypanosoma brucei brucei	39%	94%
Q9P992	Methanosarcina thermophila	31%	100%
Q9P996	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	29%	100%
Q9PTW9	Carassius auratus	43%	92%
Q9PVQ1	Xenopus laevis	44%	94%
Q9PVY6	Xenopus laevis	44%	93%
Q9QUM9	Mus musculus	32%	94%
Q9R1P0	Mus musculus	40%	89%
Q9R1P4	Mus musculus	34%	88%
Q9SXU1	Cicer arietinum	47%	93%
Q9U793	Trypanosoma brucei brucei	78%	100%
Q9UAB4	Leishmania donovani	30%	92%
Q9UT97	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	94%
Q9UXC6	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	42%	96%
Q9UXF3	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	25%	100%
Q9V0N9	Pyrococcus abyssi (strain GE5 / Orsay)	26%	100%
Q9V122	Pyrococcus abyssi (strain GE5 / Orsay)	42%	89%
Q9V247	Pyrococcus abyssi (strain GE5 / Orsay)	24%	100%
Q9V2V5	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	46%	93%
Q9V2V6	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	39%	92%
Q9V5C6	Drosophila melanogaster	31%	91%
Q9VA12	Drosophila melanogaster	40%	92%
Q9XG77	Nicotiana tabacum	32%	94%
Q9XUV0	Caenorhabditis elegans	26%	81%
Q9XZG5	Trypanosoma brucei brucei	39%	94%
Q9XZJ4	Drosophila melanogaster	29%	95%
Q9YC01	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	45%	90%
Q9YER0	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	31%	100%
Q9YES4	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	29%	100%
Q9Z2U0	Mus musculus	45%	93%
Q9Z2U1	Mus musculus	36%	96%
V5AWB3	Trypanosoma cruzi	35%	97%
V5B1X4	Trypanosoma cruzi	40%	94%
V5B4E8	Trypanosoma cruzi	39%	87%
V5BLX4	Trypanosoma cruzi	79%	100%
V5BU39	Trypanosoma cruzi	27%	74%
V5BW71	Trypanosoma cruzi	36%	74%