HMG box domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AVD6_LEIMU

TriTrypDb:

LmxM.21.1520

Length:

283

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AVD6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVD6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	184	188	PF00656	0.486
CLV_C14_Caspase3-7	277	281	PF00656	0.557
CLV_C14_Caspase3-7	37	41	PF00656	0.490
CLV_NRD_NRD_1	236	238	PF00675	0.619
CLV_NRD_NRD_1	81	83	PF00675	0.501
CLV_PCSK_KEX2_1	148	150	PF00082	0.599
CLV_PCSK_KEX2_1	236	238	PF00082	0.619
CLV_PCSK_KEX2_1	266	268	PF00082	0.529
CLV_PCSK_KEX2_1	27	29	PF00082	0.759
CLV_PCSK_KEX2_1	81	83	PF00082	0.518
CLV_PCSK_PC1ET2_1	148	150	PF00082	0.599
CLV_PCSK_PC1ET2_1	266	268	PF00082	0.529
CLV_PCSK_PC1ET2_1	27	29	PF00082	0.618
DEG_Nend_UBRbox_2	1	3	PF02207	0.538
DOC_PP2B_LxvP_1	113	116	PF13499	0.500
DOC_PP2B_LxvP_1	276	279	PF13499	0.550
DOC_USP7_MATH_1	107	111	PF00917	0.663
DOC_USP7_MATH_1	188	192	PF00917	0.709
DOC_USP7_MATH_1	207	211	PF00917	0.630
DOC_USP7_MATH_1	59	63	PF00917	0.683
DOC_USP7_UBL2_3	234	238	PF12436	0.620
DOC_WW_Pin1_4	141	146	PF00397	0.560
DOC_WW_Pin1_4	212	217	PF00397	0.666
DOC_WW_Pin1_4	278	283	PF00397	0.594
LIG_14-3-3_CanoR_1	165	169	PF00244	0.517
LIG_14-3-3_CanoR_1	221	227	PF00244	0.480
LIG_14-3-3_CanoR_1	249	258	PF00244	0.470
LIG_14-3-3_CanoR_1	81	91	PF00244	0.456
LIG_BIR_III_2	187	191	PF00653	0.650
LIG_FHA_1	165	171	PF00498	0.518
LIG_FHA_2	142	148	PF00498	0.509
LIG_FHA_2	158	164	PF00498	0.377
LIG_FHA_2	182	188	PF00498	0.607
LIG_LIR_Gen_1	139	146	PF02991	0.576
LIG_LIR_Gen_1	224	233	PF02991	0.461
LIG_LIR_Nem_3	224	229	PF02991	0.455
LIG_LIR_Nem_3	85	90	PF02991	0.421
LIG_SH2_CRK	259	263	PF00017	0.342
LIG_SH2_NCK_1	259	263	PF00017	0.460
LIG_SH2_STAP1	151	155	PF00017	0.479
LIG_SH2_STAP1	259	263	PF00017	0.460
LIG_SH2_STAP1	87	91	PF00017	0.534
LIG_SH2_STAT5	90	93	PF00017	0.543
LIG_SH3_3	112	118	PF00018	0.566
LIG_SH3_3	276	282	PF00018	0.601
LIG_SH3_3	77	83	PF00018	0.498
LIG_TRAF2_1	252	255	PF00917	0.572
MOD_CDK_SPxxK_3	141	148	PF00069	0.511
MOD_CK1_1	157	163	PF00069	0.531
MOD_CK1_1	181	187	PF00069	0.536
MOD_CK1_1	211	217	PF00069	0.600
MOD_CK1_1	222	228	PF00069	0.635
MOD_CK1_1	265	271	PF00069	0.562
MOD_CK1_1	45	51	PF00069	0.700
MOD_CK1_1	62	68	PF00069	0.527
MOD_CK2_1	141	147	PF00069	0.515
MOD_CK2_1	157	163	PF00069	0.371
MOD_CK2_1	211	217	PF00069	0.567
MOD_CK2_1	249	255	PF00069	0.454
MOD_CK2_1	51	57	PF00069	0.633
MOD_CK2_1	82	88	PF00069	0.560
MOD_Cter_Amidation	234	237	PF01082	0.618
MOD_Cter_Amidation	25	28	PF01082	0.674
MOD_GlcNHglycan	170	173	PF01048	0.616
MOD_GlcNHglycan	180	183	PF01048	0.701
MOD_GlcNHglycan	251	254	PF01048	0.454
MOD_GlcNHglycan	276	279	PF01048	0.700
MOD_GlcNHglycan	36	39	PF01048	0.585
MOD_GlcNHglycan	53	56	PF01048	0.620
MOD_GlcNHglycan	60	64	PF01048	0.650
MOD_GlcNHglycan	84	87	PF01048	0.431
MOD_GSK3_1	157	164	PF00069	0.501
MOD_GSK3_1	177	184	PF00069	0.543
MOD_GSK3_1	207	214	PF00069	0.628
MOD_GSK3_1	270	277	PF00069	0.538
MOD_GSK3_1	42	49	PF00069	0.654
MOD_GSK3_1	61	68	PF00069	0.511
MOD_N-GLC_1	249	254	PF02516	0.562
MOD_N-GLC_1	46	51	PF02516	0.691
MOD_NEK2_1	272	277	PF00069	0.488
MOD_NEK2_2	10	15	PF00069	0.420
MOD_NEK2_2	46	51	PF00069	0.666
MOD_PIKK_1	194	200	PF00454	0.557
MOD_PIKK_1	270	276	PF00454	0.642
MOD_PKA_2	164	170	PF00069	0.514
MOD_PKA_2	208	214	PF00069	0.567
MOD_Plk_1	46	52	PF00069	0.731
MOD_Plk_4	136	142	PF00069	0.607
MOD_ProDKin_1	141	147	PF00069	0.562
MOD_ProDKin_1	212	218	PF00069	0.664
MOD_SUMO_rev_2	252	258	PF00179	0.571
TRG_ENDOCYTIC_2	259	262	PF00928	0.352
TRG_ER_diArg_1	80	82	PF00400	0.504

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAX4	Leptomonas seymouri	33%	94%
A0A3Q8IL79	Leishmania donovani	86%	100%
A4HC00	Leishmania braziliensis	60%	99%
A4HZE9	Leishmania infantum	86%	100%
Q4QC43	Leishmania major	83%	100%