Ribosomal protein L1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Ribosomal protein L1p/L10e family, putative

Species:

Leishmania mexicana

UniProt:

E9AVA2_LEIMU

TriTrypDb:

LmxM.21.1180

Length:

267

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2
GO:0005840	ribosome	5	1

Expansion

Sequence features

E9AVA2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AVA2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	209	215	PF00089	0.399
CLV_NRD_NRD_1	172	174	PF00675	0.495
CLV_PCSK_KEX2_1	112	114	PF00082	0.489
CLV_PCSK_KEX2_1	120	122	PF00082	0.444
CLV_PCSK_KEX2_1	5	7	PF00082	0.446
CLV_PCSK_KEX2_1	96	98	PF00082	0.460
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.496
CLV_PCSK_PC1ET2_1	120	122	PF00082	0.433
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.446
CLV_PCSK_PC1ET2_1	96	98	PF00082	0.460
CLV_PCSK_SKI1_1	11	15	PF00082	0.464
CLV_PCSK_SKI1_1	120	124	PF00082	0.479
CLV_PCSK_SKI1_1	174	178	PF00082	0.411
DOC_ANK_TNKS_1	18	25	PF00023	0.319
DOC_CKS1_1	175	180	PF01111	0.557
DOC_MAPK_gen_1	254	263	PF00069	0.544
DOC_MAPK_MEF2A_6	257	265	PF00069	0.556
DOC_PP1_RVXF_1	255	261	PF00149	0.537
DOC_PP2B_LxvP_1	81	84	PF13499	0.368
DOC_PP4_FxxP_1	46	49	PF00568	0.388
DOC_PP4_FxxP_1	65	68	PF00568	0.432
DOC_USP7_MATH_1	163	167	PF00917	0.662
DOC_WW_Pin1_4	151	156	PF00397	0.469
DOC_WW_Pin1_4	174	179	PF00397	0.450
LIG_14-3-3_CanoR_1	124	130	PF00244	0.488
LIG_14-3-3_CanoR_1	77	84	PF00244	0.400
LIG_FHA_1	145	151	PF00498	0.573
LIG_FHA_1	195	201	PF00498	0.425
LIG_FHA_1	253	259	PF00498	0.433
LIG_FHA_1	76	82	PF00498	0.392
LIG_FHA_1	8	14	PF00498	0.429
LIG_FHA_2	175	181	PF00498	0.495
LIG_Integrin_isoDGR_2	75	77	PF01839	0.465
LIG_Integrin_RGD_1	113	115	PF01839	0.498
LIG_KLC1_Yacidic_2	40	45	PF13176	0.473
LIG_LIR_Apic_2	45	49	PF02991	0.383
LIG_LIR_Apic_2	62	68	PF02991	0.232
LIG_LIR_Gen_1	128	136	PF02991	0.379
LIG_LIR_Gen_1	40	51	PF02991	0.391
LIG_LIR_Nem_3	128	132	PF02991	0.383
LIG_LIR_Nem_3	237	241	PF02991	0.404
LIG_LIR_Nem_3	247	251	PF02991	0.353
LIG_LIR_Nem_3	40	46	PF02991	0.361
LIG_Pex14_2	238	242	PF04695	0.398
LIG_Pex14_2	46	50	PF04695	0.448
LIG_SH2_CRK	101	105	PF00017	0.413
LIG_SH2_STAP1	101	105	PF00017	0.413
LIG_SH2_STAT3	15	18	PF00017	0.561
LIG_SH2_STAT5	244	247	PF00017	0.449
LIG_SH2_STAT5	43	46	PF00017	0.463
LIG_SH3_3	166	172	PF00018	0.546
LIG_TRAF2_1	37	40	PF00917	0.540
MOD_CK1_1	153	159	PF00069	0.581
MOD_CK1_1	193	199	PF00069	0.495
MOD_CK1_1	249	255	PF00069	0.398
MOD_CK1_1	29	35	PF00069	0.680
MOD_GlcNHglycan	156	159	PF01048	0.661
MOD_GlcNHglycan	166	169	PF01048	0.645
MOD_GlcNHglycan	33	36	PF01048	0.626
MOD_GSK3_1	150	157	PF00069	0.534
MOD_GSK3_1	190	197	PF00069	0.437
MOD_GSK3_1	26	33	PF00069	0.679
MOD_N-GLC_1	252	257	PF02516	0.537
MOD_NEK2_1	190	195	PF00069	0.458
MOD_NEK2_1	230	235	PF00069	0.435
MOD_NEK2_1	50	55	PF00069	0.441
MOD_NEK2_1	7	12	PF00069	0.415
MOD_PIKK_1	190	196	PF00454	0.457
MOD_PKA_2	184	190	PF00069	0.481
MOD_PKA_2	76	82	PF00069	0.411
MOD_Plk_1	246	252	PF00069	0.497
MOD_Plk_4	237	243	PF00069	0.414
MOD_ProDKin_1	151	157	PF00069	0.479
MOD_ProDKin_1	174	180	PF00069	0.457
MOD_SUMO_for_1	234	237	PF00179	0.454
TRG_DiLeu_BaEn_2	255	261	PF01217	0.445
TRG_DiLeu_BaEn_4	39	45	PF01217	0.442
TRG_DiLeu_BaLyEn_6	3	8	PF01217	0.473
TRG_ENDOCYTIC_2	101	104	PF00928	0.414
TRG_ENDOCYTIC_2	43	46	PF00928	0.437
TRG_ER_diArg_1	257	260	PF00400	0.538
TRG_Pf-PMV_PEXEL_1	243	247	PF00026	0.490

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HUF4	Leptomonas seymouri	77%	100%
A0A0S4JGP8	Bodo saltans	48%	100%
A0A1X0NYA3	Trypanosomatidae	54%	89%
A0A3Q8IC01	Leishmania donovani	93%	100%
A0A3R7N930	Trypanosoma rangeli	53%	92%
A4HBX4	Leishmania braziliensis	86%	98%
A4HZ94	Leishmania infantum	93%	100%
D0A178	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	90%
Q4QC78	Leishmania major	94%	100%