A single-pass helical protein with a potential mitochondrial transit signal. Localization: Mitochondrial (by homology)
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 8 |
| NetGPI | no | yes: 0, no: 8 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 7 |
| GO:0110165 | cellular anatomical entity | 1 | 7 |
| GO:0005739 | mitochondrion | 5 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043227 | membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
Related structures:
AlphaFold database: E9AV83
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 58 | 60 | PF00675 | 0.381 |
| CLV_NRD_NRD_1 | 73 | 75 | PF00675 | 0.335 |
| CLV_PCSK_KEX2_1 | 58 | 60 | PF00082 | 0.398 |
| CLV_PCSK_KEX2_1 | 73 | 75 | PF00082 | 0.333 |
| CLV_PCSK_SKI1_1 | 131 | 135 | PF00082 | 0.375 |
| CLV_PCSK_SKI1_1 | 60 | 64 | PF00082 | 0.350 |
| CLV_PCSK_SKI1_1 | 74 | 78 | PF00082 | 0.373 |
| DEG_APCC_DBOX_1 | 73 | 81 | PF00400 | 0.649 |
| DOC_MAPK_gen_1 | 122 | 130 | PF00069 | 0.626 |
| DOC_MAPK_gen_1 | 70 | 80 | PF00069 | 0.639 |
| DOC_USP7_MATH_1 | 138 | 142 | PF00917 | 0.601 |
| DOC_WW_Pin1_4 | 16 | 21 | PF00397 | 0.335 |
| DOC_WW_Pin1_4 | 8 | 13 | PF00397 | 0.343 |
| LIG_14-3-3_CanoR_1 | 91 | 98 | PF00244 | 0.594 |
| LIG_BRCT_BRCA1_1 | 42 | 46 | PF00533 | 0.572 |
| LIG_Clathr_ClatBox_1 | 77 | 81 | PF01394 | 0.659 |
| LIG_FHA_1 | 19 | 25 | PF00498 | 0.178 |
| LIG_FHA_2 | 64 | 70 | PF00498 | 0.491 |
| LIG_MLH1_MIPbox_1 | 42 | 46 | PF16413 | 0.544 |
| LIG_PALB2_WD40_1 | 5 | 13 | PF16756 | 0.395 |
| LIG_PDZ_Class_3 | 137 | 142 | PF00595 | 0.628 |
| LIG_SH2_SRC | 40 | 43 | PF00017 | 0.590 |
| LIG_SH2_STAT5 | 23 | 26 | PF00017 | 0.317 |
| LIG_SH2_STAT5 | 4 | 7 | PF00017 | 0.386 |
| LIG_SH2_STAT5 | 45 | 48 | PF00017 | 0.578 |
| LIG_SH2_STAT5 | 65 | 68 | PF00017 | 0.485 |
| LIG_SH3_3 | 2 | 8 | PF00018 | 0.388 |
| LIG_SUMO_SIM_par_1 | 93 | 101 | PF11976 | 0.635 |
| LIG_UBA3_1 | 126 | 134 | PF00899 | 0.606 |
| MOD_CK1_1 | 18 | 24 | PF00069 | 0.320 |
| MOD_CK1_1 | 97 | 103 | PF00069 | 0.633 |
| MOD_CK2_1 | 63 | 69 | PF00069 | 0.538 |
| MOD_GlcNHglycan | 92 | 95 | PF01048 | 0.429 |
| MOD_GSK3_1 | 90 | 97 | PF00069 | 0.678 |
| MOD_NEK2_1 | 15 | 20 | PF00069 | 0.397 |
| MOD_PIKK_1 | 98 | 104 | PF00454 | 0.562 |
| MOD_PKA_2 | 90 | 96 | PF00069 | 0.598 |
| MOD_ProDKin_1 | 16 | 22 | PF00069 | 0.333 |
| MOD_ProDKin_1 | 8 | 14 | PF00069 | 0.338 |
| MOD_SUMO_rev_2 | 129 | 135 | PF00179 | 0.649 |
| TRG_ENDOCYTIC_2 | 23 | 26 | PF00928 | 0.392 |
| TRG_ENDOCYTIC_2 | 65 | 68 | PF00928 | 0.548 |
| TRG_ER_diArg_1 | 57 | 59 | PF00400 | 0.593 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P3R0 | Leptomonas seymouri | 74% | 100% |
| A0A1X0NYD4 | Trypanosomatidae | 62% | 100% |
| A0A3Q8IBW9 | Leishmania donovani | 95% | 100% |
| A4HBV9 | Leishmania braziliensis | 90% | 100% |
| D0A199 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 59% | 96% |
| E9AGW7 | Leishmania infantum | 95% | 100% |
| Q4QC97 | Leishmania major | 94% | 100% |