Histone H2A

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Histone H2A

Gene product:

histone H2A

Species:

Leishmania mexicana

UniProt:

E9AV76_LEIMU

TriTrypDb:

LmxM.21.0915

Length:

179

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 3
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AV76

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AV76

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	150	152	PF00675	0.562
CLV_NRD_NRD_1	40	42	PF00675	0.619
CLV_NRD_NRD_1	90	92	PF00675	0.525
CLV_PCSK_KEX2_1	150	152	PF00082	0.554
CLV_PCSK_KEX2_1	154	156	PF00082	0.649
CLV_PCSK_KEX2_1	90	92	PF00082	0.529
CLV_PCSK_PC1ET2_1	154	156	PF00082	0.544
CLV_PCSK_PC7_1	150	156	PF00082	0.541
CLV_PCSK_PC7_1	86	92	PF00082	0.645
CLV_PCSK_SKI1_1	9	13	PF00082	0.490
DEG_Nend_UBRbox_4	1	3	PF02207	0.568
DEG_SCF_FBW7_1	33	38	PF00400	0.534
DOC_PP1_RVXF_1	84	90	PF00149	0.492
DOC_PP4_FxxP_1	36	39	PF00568	0.557
DOC_USP7_MATH_1	80	84	PF00917	0.479
DOC_WW_Pin1_4	173	178	PF00397	0.597
DOC_WW_Pin1_4	21	26	PF00397	0.525
DOC_WW_Pin1_4	29	34	PF00397	0.515
DOC_WW_Pin1_4	35	40	PF00397	0.493
LIG_14-3-3_CanoR_1	5	13	PF00244	0.510
LIG_14-3-3_CanoR_1	79	89	PF00244	0.485
LIG_FHA_1	32	38	PF00498	0.544
LIG_FHA_2	112	118	PF00498	0.557
LIG_LIR_Apic_2	34	39	PF02991	0.534
LIG_LIR_Gen_1	15	25	PF02991	0.521
LIG_LIR_Nem_3	15	21	PF02991	0.516
LIG_MYND_1	35	39	PF01753	0.617
LIG_SH2_STAT3	45	48	PF00017	0.654
LIG_SH3_3	118	124	PF00018	0.786
LIG_SH3_3	172	178	PF00018	0.595
LIG_SH3_3	22	28	PF00018	0.639
LIG_SH3_3	62	68	PF00018	0.626
LIG_TRAF2_1	140	143	PF00917	0.695
MOD_CDC14_SPxK_1	38	41	PF00782	0.531
MOD_CDK_SPxK_1	35	41	PF00069	0.534
MOD_CDK_SPxxK_3	35	42	PF00069	0.532
MOD_CK2_1	111	117	PF00069	0.560
MOD_CK2_1	155	161	PF00069	0.541
MOD_GSK3_1	23	30	PF00069	0.532
MOD_GSK3_1	31	38	PF00069	0.654
MOD_GSK3_1	9	16	PF00069	0.621
MOD_NEK2_1	13	18	PF00069	0.558
MOD_OFUCOSY	152	159	PF10250	0.540
MOD_PIKK_1	145	151	PF00454	0.685
MOD_PIKK_1	44	50	PF00454	0.655
MOD_PKA_1	150	156	PF00069	0.541
MOD_PKA_2	150	156	PF00069	0.629
MOD_PKA_2	4	10	PF00069	0.517
MOD_PKA_2	81	87	PF00069	0.482
MOD_Plk_4	13	19	PF00069	0.508
MOD_ProDKin_1	173	179	PF00069	0.602
MOD_ProDKin_1	21	27	PF00069	0.524
MOD_ProDKin_1	29	35	PF00069	0.515
TRG_DiLeu_BaLyEn_6	83	88	PF01217	0.485
TRG_ER_diArg_1	133	136	PF00400	0.766
TRG_ER_diArg_1	89	91	PF00400	0.516

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I4N2	Leishmania infantum	66%	75%
A4I4N3	Leishmania infantum	77%	100%
A4I4N4	Leishmania infantum	79%	93%