Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AV73_LEIMU

TriTrypDb:

LmxM.21.0901

Length:

415

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AV73

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AV73

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	273	277	PF00656	0.568
CLV_C14_Caspase3-7	83	87	PF00656	0.533
CLV_NRD_NRD_1	13	15	PF00675	0.582
CLV_NRD_NRD_1	327	329	PF00675	0.543
CLV_NRD_NRD_1	54	56	PF00675	0.657
CLV_PCSK_KEX2_1	13	15	PF00082	0.587
CLV_PCSK_KEX2_1	209	211	PF00082	0.631
CLV_PCSK_KEX2_1	326	328	PF00082	0.544
CLV_PCSK_KEX2_1	54	56	PF00082	0.657
CLV_PCSK_PC1ET2_1	209	211	PF00082	0.631
CLV_PCSK_SKI1_1	108	112	PF00082	0.547
CLV_PCSK_SKI1_1	255	259	PF00082	0.644
CLV_PCSK_SKI1_1	321	325	PF00082	0.484
CLV_PCSK_SKI1_1	390	394	PF00082	0.610
DEG_APCC_DBOX_1	103	111	PF00400	0.653
DEG_APCC_DBOX_1	235	243	PF00400	0.647
DEG_Nend_Nbox_1	1	3	PF02207	0.590
DOC_CYCLIN_RxL_1	163	171	PF00134	0.624
DOC_MAPK_MEF2A_6	355	364	PF00069	0.488
DOC_PP1_RVXF_1	164	171	PF00149	0.571
DOC_PP2B_LxvP_1	115	118	PF13499	0.494
DOC_USP7_MATH_1	149	153	PF00917	0.555
DOC_USP7_MATH_1	24	28	PF00917	0.635
DOC_USP7_MATH_1	250	254	PF00917	0.601
DOC_USP7_MATH_1	275	279	PF00917	0.686
DOC_USP7_MATH_1	287	291	PF00917	0.650
DOC_USP7_MATH_1	344	348	PF00917	0.537
DOC_USP7_MATH_1	56	60	PF00917	0.593
DOC_USP7_MATH_1	61	65	PF00917	0.620
DOC_USP7_MATH_1	82	86	PF00917	0.491
DOC_WW_Pin1_4	191	196	PF00397	0.627
DOC_WW_Pin1_4	20	25	PF00397	0.533
DOC_WW_Pin1_4	283	288	PF00397	0.584
DOC_WW_Pin1_4	348	353	PF00397	0.462
LIG_14-3-3_CanoR_1	14	24	PF00244	0.591
LIG_14-3-3_CanoR_1	143	150	PF00244	0.526
LIG_14-3-3_CanoR_1	255	265	PF00244	0.601
LIG_14-3-3_CanoR_1	390	398	PF00244	0.602
LIG_14-3-3_CanoR_1	72	76	PF00244	0.466
LIG_FHA_1	119	125	PF00498	0.594
LIG_FHA_1	149	155	PF00498	0.587
LIG_FHA_1	157	163	PF00498	0.604
LIG_FHA_1	75	81	PF00498	0.565
LIG_FHA_2	137	143	PF00498	0.581
LIG_FHA_2	271	277	PF00498	0.583
LIG_FHA_2	297	303	PF00498	0.568
LIG_LIR_Gen_1	312	320	PF02991	0.458
LIG_LIR_Gen_1	369	379	PF02991	0.652
LIG_LIR_Gen_1	411	415	PF02991	0.570
LIG_LIR_Nem_3	181	185	PF02991	0.548
LIG_LIR_Nem_3	199	204	PF02991	0.655
LIG_LIR_Nem_3	253	257	PF02991	0.595
LIG_LIR_Nem_3	312	316	PF02991	0.451
LIG_LIR_Nem_3	369	375	PF02991	0.520
LIG_LIR_Nem_3	411	415	PF02991	0.570
LIG_MYND_1	289	293	PF01753	0.641
LIG_NRBOX	106	112	PF00104	0.492
LIG_PCNA_PIPBox_1	100	109	PF02747	0.536
LIG_PCNA_yPIPBox_3	317	328	PF02747	0.487
LIG_SH2_CRK	201	205	PF00017	0.523
LIG_SH2_PTP2	313	316	PF00017	0.510
LIG_SH2_SRC	309	312	PF00017	0.545
LIG_SH2_STAP1	333	337	PF00017	0.585
LIG_SH2_STAP1	372	376	PF00017	0.521
LIG_SH2_STAT5	167	170	PF00017	0.631
LIG_SH2_STAT5	309	312	PF00017	0.490
LIG_SH2_STAT5	313	316	PF00017	0.455
LIG_SH2_STAT5	333	336	PF00017	0.569
LIG_SH2_STAT5	94	97	PF00017	0.555
LIG_SH3_3	279	285	PF00018	0.621
LIG_SH3_3	286	292	PF00018	0.579
LIG_SH3_3	346	352	PF00018	0.596
LIG_SH3_3	359	365	PF00018	0.449
LIG_SH3_3	87	93	PF00018	0.546
LIG_SH3_5	329	333	PF00018	0.594
MOD_CDK_SPxxK_3	348	355	PF00069	0.455
MOD_CK1_1	136	142	PF00069	0.624
MOD_CK1_1	189	195	PF00069	0.625
MOD_CK1_1	270	276	PF00069	0.646
MOD_CK1_1	59	65	PF00069	0.598
MOD_CK1_1	71	77	PF00069	0.520
MOD_CK2_1	296	302	PF00069	0.521
MOD_GlcNHglycan	151	154	PF01048	0.549
MOD_GlcNHglycan	162	165	PF01048	0.465
MOD_GlcNHglycan	196	199	PF01048	0.634
MOD_GlcNHglycan	26	29	PF01048	0.697
MOD_GlcNHglycan	265	268	PF01048	0.729
MOD_GlcNHglycan	269	272	PF01048	0.577
MOD_GlcNHglycan	278	281	PF01048	0.642
MOD_GlcNHglycan	338	341	PF01048	0.511
MOD_GlcNHglycan	65	68	PF01048	0.642
MOD_GlcNHglycan	7	10	PF01048	0.575
MOD_GlcNHglycan	86	89	PF01048	0.560
MOD_GSK3_1	154	161	PF00069	0.654
MOD_GSK3_1	20	27	PF00069	0.589
MOD_GSK3_1	263	270	PF00069	0.688
MOD_GSK3_1	283	290	PF00069	0.744
MOD_GSK3_1	305	312	PF00069	0.494
MOD_GSK3_1	327	334	PF00069	0.741
MOD_GSK3_1	344	351	PF00069	0.640
MOD_GSK3_1	35	42	PF00069	0.616
MOD_GSK3_1	366	373	PF00069	0.520
MOD_GSK3_1	56	63	PF00069	0.607
MOD_GSK3_1	84	91	PF00069	0.568
MOD_NEK2_1	120	125	PF00069	0.625
MOD_NEK2_1	168	173	PF00069	0.696
MOD_NEK2_1	269	274	PF00069	0.504
MOD_NEK2_1	39	44	PF00069	0.620
MOD_NEK2_1	402	407	PF00069	0.653
MOD_NEK2_1	5	10	PF00069	0.536
MOD_NEK2_1	60	65	PF00069	0.626
MOD_NEK2_2	250	255	PF00069	0.599
MOD_PIKK_1	156	162	PF00454	0.588
MOD_PIKK_1	384	390	PF00454	0.500
MOD_PKA_1	327	333	PF00069	0.531
MOD_PKA_2	142	148	PF00069	0.522
MOD_PKA_2	15	21	PF00069	0.682
MOD_PKA_2	261	267	PF00069	0.488
MOD_PKA_2	327	333	PF00069	0.531
MOD_PKA_2	5	11	PF00069	0.607
MOD_PKA_2	71	77	PF00069	0.458
MOD_Plk_1	186	192	PF00069	0.476
MOD_Plk_4	186	192	PF00069	0.538
MOD_Plk_4	221	227	PF00069	0.713
MOD_Plk_4	230	236	PF00069	0.584
MOD_Plk_4	296	302	PF00069	0.521
MOD_Plk_4	305	311	PF00069	0.494
MOD_ProDKin_1	191	197	PF00069	0.629
MOD_ProDKin_1	20	26	PF00069	0.530
MOD_ProDKin_1	283	289	PF00069	0.581
MOD_ProDKin_1	348	354	PF00069	0.458
TRG_DiLeu_BaLyEn_6	111	116	PF01217	0.560
TRG_DiLeu_LyEn_5	241	246	PF01217	0.604
TRG_ENDOCYTIC_2	167	170	PF00928	0.631
TRG_ENDOCYTIC_2	201	204	PF00928	0.667
TRG_ENDOCYTIC_2	313	316	PF00928	0.510
TRG_ENDOCYTIC_2	372	375	PF00928	0.468
TRG_ENDOCYTIC_2	412	415	PF00928	0.575
TRG_ER_diArg_1	13	16	PF00400	0.766
TRG_ER_diArg_1	325	328	PF00400	0.547
TRG_Pf-PMV_PEXEL_1	108	113	PF00026	0.550

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDR9	Leptomonas seymouri	37%	93%
A0A3Q8IAW3	Leishmania donovani	82%	98%
E9AGV7	Leishmania infantum	82%	98%
Q4QCA8	Leishmania major	80%	100%