LeishMANIAdb
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DUF4042 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF4042 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AV66_LEIMU
TriTrypDb:
LmxM.21.0875
Length:
1269

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AV66
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AV66

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 236 240 PF00656 0.537
CLV_C14_Caspase3-7 368 372 PF00656 0.817
CLV_C14_Caspase3-7 461 465 PF00656 0.700
CLV_C14_Caspase3-7 952 956 PF00656 0.596
CLV_NRD_NRD_1 1122 1124 PF00675 0.492
CLV_NRD_NRD_1 911 913 PF00675 0.522
CLV_PCSK_FUR_1 909 913 PF00082 0.515
CLV_PCSK_KEX2_1 1122 1124 PF00082 0.437
CLV_PCSK_KEX2_1 911 913 PF00082 0.522
CLV_PCSK_SKI1_1 1004 1008 PF00082 0.463
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I1M1 Leptomonas seymouri 51% 99%
A0A3Q8IBY1 Leishmania donovani 89% 99%
A4HBU4 Leishmania braziliensis 77% 99%
E9AGV0 Leishmania infantum 89% 99%
Q4QCB5 Leishmania major 88% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS