Guanylate cyclase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Guanylate cyclase

Gene product:

serine/threonine protein kinase, putative

Species:

Leishmania mexicana

UniProt:

E9AUY0_LEIMU

TriTrypDb:

LmxM.21.0130

Length:

1692

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5
GO:0005737	cytoplasm	2	1

Expansion

Sequence features

E9AUY0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	6
GO:0006163	purine nucleotide metabolic process	5	6
GO:0006164	purine nucleotide biosynthetic process	6	6
GO:0006171	cAMP biosynthetic process	8	6
GO:0006182	cGMP biosynthetic process	8	6
GO:0006468	protein phosphorylation	5	6
GO:0006725	cellular aromatic compound metabolic process	3	6
GO:0006753	nucleoside phosphate metabolic process	4	6
GO:0006793	phosphorus metabolic process	3	6
GO:0006796	phosphate-containing compound metabolic process	4	6
GO:0006807	nitrogen compound metabolic process	2	6
GO:0008152	metabolic process	1	6
GO:0009058	biosynthetic process	2	6
GO:0009117	nucleotide metabolic process	5	6
GO:0009150	purine ribonucleotide metabolic process	6	6
GO:0009152	purine ribonucleotide biosynthetic process	7	6
GO:0009165	nucleotide biosynthetic process	6	6
GO:0009187	cyclic nucleotide metabolic process	6	6
GO:0009190	cyclic nucleotide biosynthetic process	7	6
GO:0009259	ribonucleotide metabolic process	5	6
GO:0009260	ribonucleotide biosynthetic process	6	6
GO:0009987	cellular process	1	6
GO:0016310	phosphorylation	5	6
GO:0018130	heterocycle biosynthetic process	4	6
GO:0019438	aromatic compound biosynthetic process	4	6
GO:0019538	protein metabolic process	3	6
GO:0019637	organophosphate metabolic process	3	6
GO:0019693	ribose phosphate metabolic process	4	6
GO:0034641	cellular nitrogen compound metabolic process	3	6
GO:0034654	nucleobase-containing compound biosynthetic process	4	6
GO:0036211	protein modification process	4	6
GO:0043170	macromolecule metabolic process	3	6
GO:0043412	macromolecule modification	4	6
GO:0044237	cellular metabolic process	2	6
GO:0044238	primary metabolic process	2	6
GO:0044249	cellular biosynthetic process	3	6
GO:0044271	cellular nitrogen compound biosynthetic process	4	6
GO:0044281	small molecule metabolic process	2	6
GO:0046058	cAMP metabolic process	7	6
GO:0046068	cGMP metabolic process	7	6
GO:0046390	ribose phosphate biosynthetic process	5	6
GO:0046483	heterocycle metabolic process	3	6
GO:0052652	cyclic purine nucleotide metabolic process	6	6
GO:0055086	nucleobase-containing small molecule metabolic process	3	6
GO:0071704	organic substance metabolic process	2	6
GO:0072521	purine-containing compound metabolic process	4	6
GO:0072522	purine-containing compound biosynthetic process	5	6
GO:0090407	organophosphate biosynthetic process	4	6
GO:1901135	carbohydrate derivative metabolic process	3	6
GO:1901137	carbohydrate derivative biosynthetic process	4	6
GO:1901293	nucleoside phosphate biosynthetic process	5	6
GO:1901360	organic cyclic compound metabolic process	3	6
GO:1901362	organic cyclic compound biosynthetic process	4	6
GO:1901564	organonitrogen compound metabolic process	3	6
GO:1901566	organonitrogen compound biosynthetic process	4	6
GO:1901576	organic substance biosynthetic process	3	6

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	6
GO:0003824	catalytic activity	1	6
GO:0004672	protein kinase activity	3	6
GO:0005488	binding	1	6
GO:0005524	ATP binding	5	6
GO:0016301	kinase activity	4	6
GO:0016740	transferase activity	2	6
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	6
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	6
GO:0017076	purine nucleotide binding	4	6
GO:0030554	adenyl nucleotide binding	5	6
GO:0032553	ribonucleotide binding	3	6
GO:0032555	purine ribonucleotide binding	4	6
GO:0032559	adenyl ribonucleotide binding	5	6
GO:0035639	purine ribonucleoside triphosphate binding	4	6
GO:0036094	small molecule binding	2	6
GO:0043167	ion binding	2	6
GO:0043168	anion binding	3	6
GO:0097159	organic cyclic compound binding	2	6
GO:0097367	carbohydrate derivative binding	2	6
GO:0140096	catalytic activity, acting on a protein	2	6
GO:1901265	nucleoside phosphate binding	3	6
GO:1901363	heterocyclic compound binding	2	6
GO:0004674	protein serine/threonine kinase activity	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1378	1382	PF00656	0.685
CLV_C14_Caspase3-7	1660	1664	PF00656	0.612
CLV_C14_Caspase3-7	260	264	PF00656	0.679
CLV_C14_Caspase3-7	740	744	PF00656	0.773
CLV_NRD_NRD_1	1114	1116	PF00675	0.369
CLV_NRD_NRD_1	1202	1204	PF00675	0.495
CLV_NRD_NRD_1	131	133	PF00675	0.431
CLV_NRD_NRD_1	149	151	PF00675	0.500
CLV_NRD_NRD_1	1583	1585	PF00675	0.303
CLV_NRD_NRD_1	161	163	PF00675	0.390
CLV_NRD_NRD_1	535	537	PF00675	0.262
CLV_NRD_NRD_1	667	669	PF00675	0.363
CLV_NRD_NRD_1	719	721	PF00675	0.378
CLV_NRD_NRD_1	806	808	PF00675	0.421
CLV_NRD_NRD_1	875	877	PF00675	0.389
CLV_NRD_NRD_1	906	908	PF00675	0.388
CLV_NRD_NRD_1	917	919	PF00675	0.310
CLV_PCSK_FUR_1	915	919	PF00082	0.364
CLV_PCSK_KEX2_1	1114	1116	PF00082	0.369
CLV_PCSK_KEX2_1	1202	1204	PF00082	0.495
CLV_PCSK_KEX2_1	131	133	PF00082	0.520
CLV_PCSK_KEX2_1	161	163	PF00082	0.494
CLV_PCSK_KEX2_1	1677	1679	PF00082	0.342
CLV_PCSK_KEX2_1	718	720	PF00082	0.377
CLV_PCSK_KEX2_1	762	764	PF00082	0.498
CLV_PCSK_KEX2_1	806	808	PF00082	0.421
CLV_PCSK_KEX2_1	875	877	PF00082	0.389
CLV_PCSK_KEX2_1	906	908	PF00082	0.388
CLV_PCSK_KEX2_1	917	919	PF00082	0.324
CLV_PCSK_PC1ET2_1	1677	1679	PF00082	0.342
CLV_PCSK_PC1ET2_1	762	764	PF00082	0.498
CLV_PCSK_PC7_1	127	133	PF00082	0.560
CLV_PCSK_SKI1_1	1023	1027	PF00082	0.431
CLV_PCSK_SKI1_1	1191	1195	PF00082	0.437
CLV_PCSK_SKI1_1	1536	1540	PF00082	0.411
CLV_PCSK_SKI1_1	1553	1557	PF00082	0.234
CLV_PCSK_SKI1_1	314	318	PF00082	0.625
CLV_PCSK_SKI1_1	45	49	PF00082	0.271
CLV_PCSK_SKI1_1	590	594	PF00082	0.228
CLV_PCSK_SKI1_1	762	766	PF00082	0.503
CLV_PCSK_SKI1_1	910	914	PF00082	0.359
CLV_PCSK_SKI1_1	920	924	PF00082	0.317
CLV_PCSK_SKI1_1	987	991	PF00082	0.376
CLV_PCSK_SKI1_1	999	1003	PF00082	0.381
DEG_APCC_DBOX_1	1535	1543	PF00400	0.612
DEG_APCC_DBOX_1	48	56	PF00400	0.678
DEG_APCC_DBOX_1	675	683	PF00400	0.517
DEG_APCC_DBOX_1	909	917	PF00400	0.591
DEG_Nend_UBRbox_3	1	3	PF02207	0.626
DEG_SCF_FBW7_1	1286	1293	PF00400	0.578
DEG_SCF_FBW7_2	558	565	PF00400	0.670
DEG_SPOP_SBC_1	1307	1311	PF00917	0.516
DOC_CDC14_PxL_1	1177	1185	PF14671	0.675
DOC_CKS1_1	403	408	PF01111	0.477
DOC_CKS1_1	559	564	PF01111	0.676
DOC_CYCLIN_RxL_1	1457	1470	PF00134	0.612
DOC_CYCLIN_RxL_1	276	287	PF00134	0.559
DOC_CYCLIN_yCln2_LP_2	1241	1247	PF00134	0.715
DOC_MAPK_gen_1	1114	1121	PF00069	0.567
DOC_MAPK_gen_1	150	156	PF00069	0.724
DOC_MAPK_gen_1	1553	1562	PF00069	0.542
DOC_MAPK_gen_1	161	170	PF00069	0.558
DOC_MAPK_gen_1	541	548	PF00069	0.465
DOC_MAPK_gen_1	668	679	PF00069	0.620
DOC_MAPK_gen_1	7	15	PF00069	0.562
DOC_MAPK_gen_1	762	770	PF00069	0.509
DOC_MAPK_gen_1	906	913	PF00069	0.598
DOC_MAPK_MEF2A_6	1287	1294	PF00069	0.737
DOC_MAPK_MEF2A_6	1556	1564	PF00069	0.542
DOC_MAPK_MEF2A_6	45	52	PF00069	0.597
DOC_MAPK_MEF2A_6	687	696	PF00069	0.546
DOC_MAPK_MEF2A_6	906	913	PF00069	0.598
DOC_MAPK_MEF2A_6	963	971	PF00069	0.577
DOC_PP1_RVXF_1	283	289	PF00149	0.542
DOC_PP1_RVXF_1	388	394	PF00149	0.450
DOC_PP1_RVXF_1	667	674	PF00149	0.555
DOC_PP2B_LxvP_1	1067	1070	PF13499	0.630
DOC_PP2B_LxvP_1	1241	1244	PF13499	0.712
DOC_PP2B_LxvP_1	1464	1467	PF13499	0.542
DOC_PP4_FxxP_1	239	242	PF00568	0.766
DOC_PP4_FxxP_1	477	480	PF00568	0.636
DOC_PP4_FxxP_1	593	596	PF00568	0.515
DOC_USP7_MATH_1	104	108	PF00917	0.642
DOC_USP7_MATH_1	1058	1062	PF00917	0.739
DOC_USP7_MATH_1	121	125	PF00917	0.693
DOC_USP7_MATH_1	1235	1239	PF00917	0.754
DOC_USP7_MATH_1	1263	1267	PF00917	0.556
DOC_USP7_MATH_1	1279	1283	PF00917	0.763
DOC_USP7_MATH_1	1308	1312	PF00917	0.521
DOC_USP7_MATH_1	1339	1343	PF00917	0.649
DOC_USP7_MATH_1	1392	1396	PF00917	0.642
DOC_USP7_MATH_1	1465	1469	PF00917	0.542
DOC_USP7_MATH_1	24	28	PF00917	0.562
DOC_USP7_MATH_1	242	246	PF00917	0.703
DOC_USP7_MATH_1	247	251	PF00917	0.747
DOC_USP7_MATH_1	61	65	PF00917	0.663
DOC_USP7_MATH_1	656	660	PF00917	0.644
DOC_USP7_MATH_1	781	785	PF00917	0.691
DOC_USP7_MATH_1	810	814	PF00917	0.691
DOC_USP7_MATH_1	961	965	PF00917	0.646
DOC_USP7_UBL2_3	390	394	PF12436	0.515
DOC_WW_Pin1_4	1054	1059	PF00397	0.695
DOC_WW_Pin1_4	1203	1208	PF00397	0.718
DOC_WW_Pin1_4	1213	1218	PF00397	0.664
DOC_WW_Pin1_4	1236	1241	PF00397	0.651
DOC_WW_Pin1_4	1286	1291	PF00397	0.598
DOC_WW_Pin1_4	1326	1331	PF00397	0.758
DOC_WW_Pin1_4	1359	1364	PF00397	0.626
DOC_WW_Pin1_4	149	154	PF00397	0.722
DOC_WW_Pin1_4	1591	1596	PF00397	0.536
DOC_WW_Pin1_4	1603	1608	PF00397	0.542
DOC_WW_Pin1_4	1628	1633	PF00397	0.576
DOC_WW_Pin1_4	20	25	PF00397	0.733
DOC_WW_Pin1_4	225	230	PF00397	0.721
DOC_WW_Pin1_4	238	243	PF00397	0.534
DOC_WW_Pin1_4	402	407	PF00397	0.474
DOC_WW_Pin1_4	501	506	PF00397	0.700
DOC_WW_Pin1_4	522	527	PF00397	0.566
DOC_WW_Pin1_4	558	563	PF00397	0.598
DOC_WW_Pin1_4	59	64	PF00397	0.685
DOC_WW_Pin1_4	661	666	PF00397	0.649
DOC_WW_Pin1_4	71	76	PF00397	0.784
DOC_WW_Pin1_4	745	750	PF00397	0.787
DOC_WW_Pin1_4	797	802	PF00397	0.711
DOC_WW_Pin1_4	92	97	PF00397	0.666
LIG_14-3-3_CanoR_1	105	112	PF00244	0.645
LIG_14-3-3_CanoR_1	1102	1112	PF00244	0.622
LIG_14-3-3_CanoR_1	1343	1351	PF00244	0.535
LIG_14-3-3_CanoR_1	167	175	PF00244	0.552
LIG_14-3-3_CanoR_1	1678	1685	PF00244	0.542
LIG_14-3-3_CanoR_1	203	209	PF00244	0.544
LIG_14-3-3_CanoR_1	220	226	PF00244	0.720
LIG_14-3-3_CanoR_1	234	240	PF00244	0.800
LIG_14-3-3_CanoR_1	285	289	PF00244	0.393
LIG_14-3-3_CanoR_1	499	505	PF00244	0.534
LIG_14-3-3_CanoR_1	536	545	PF00244	0.633
LIG_14-3-3_CanoR_1	672	676	PF00244	0.606
LIG_14-3-3_CanoR_1	789	796	PF00244	0.715
LIG_Actin_WH2_2	1274	1289	PF00022	0.649
LIG_APCC_ABBA_1	1504	1509	PF00400	0.612
LIG_APCC_ABBA_1	382	387	PF00400	0.514
LIG_APCC_ABBAyCdc20_2	1173	1179	PF00400	0.499
LIG_BRCT_BRCA1_1	1495	1499	PF00533	0.542
LIG_BRCT_BRCA1_1	204	208	PF00533	0.659
LIG_BRCT_BRCA1_1	415	419	PF00533	0.458
LIG_BRCT_BRCA1_1	692	696	PF00533	0.536
LIG_Clathr_ClatBox_1	1047	1051	PF01394	0.608
LIG_deltaCOP1_diTrp_1	1612	1620	PF00928	0.542
LIG_eIF4E_1	340	346	PF01652	0.504
LIG_eIF4E_1	648	654	PF01652	0.524
LIG_FHA_1	1011	1017	PF00498	0.556
LIG_FHA_1	1161	1167	PF00498	0.681
LIG_FHA_1	1287	1293	PF00498	0.610
LIG_FHA_1	1360	1366	PF00498	0.659
LIG_FHA_1	1378	1384	PF00498	0.617
LIG_FHA_1	1417	1423	PF00498	0.621
LIG_FHA_1	1428	1434	PF00498	0.599
LIG_FHA_1	1487	1493	PF00498	0.542
LIG_FHA_1	1501	1507	PF00498	0.482
LIG_FHA_1	1528	1534	PF00498	0.534
LIG_FHA_1	1623	1629	PF00498	0.542
LIG_FHA_1	213	219	PF00498	0.664
LIG_FHA_1	285	291	PF00498	0.393
LIG_FHA_1	319	325	PF00498	0.501
LIG_FHA_1	386	392	PF00498	0.556
LIG_FHA_1	465	471	PF00498	0.542
LIG_FHA_1	482	488	PF00498	0.515
LIG_FHA_1	529	535	PF00498	0.476
LIG_FHA_1	554	560	PF00498	0.597
LIG_FHA_1	614	620	PF00498	0.568
LIG_FHA_1	641	647	PF00498	0.407
LIG_FHA_1	672	678	PF00498	0.548
LIG_FHA_1	878	884	PF00498	0.639
LIG_FHA_1	986	992	PF00498	0.645
LIG_FHA_2	1069	1075	PF00498	0.681
LIG_FHA_2	1376	1382	PF00498	0.684
LIG_FHA_2	364	370	PF00498	0.565
LIG_FHA_2	403	409	PF00498	0.563
LIG_FHA_2	446	452	PF00498	0.698
LIG_FHA_2	7	13	PF00498	0.679
LIG_FHA_2	732	738	PF00498	0.693
LIG_FHA_2	778	784	PF00498	0.646
LIG_FHA_2	793	799	PF00498	0.683
LIG_FHA_2	810	816	PF00498	0.708
LIG_IRF3_LxIS_1	1249	1254	PF10401	0.607
LIG_LIR_Apic_2	1594	1600	PF02991	0.542
LIG_LIR_Apic_2	237	242	PF02991	0.780
LIG_LIR_Apic_2	373	379	PF02991	0.519
LIG_LIR_Apic_2	474	480	PF02991	0.627
LIG_LIR_Gen_1	139	148	PF02991	0.727
LIG_LIR_Gen_1	155	165	PF02991	0.496
LIG_LIR_Gen_1	16	26	PF02991	0.680
LIG_LIR_Gen_1	343	354	PF02991	0.426
LIG_LIR_Gen_1	416	425	PF02991	0.518
LIG_LIR_Gen_1	442	451	PF02991	0.623
LIG_LIR_Gen_1	488	498	PF02991	0.668
LIG_LIR_Gen_1	514	523	PF02991	0.587
LIG_LIR_Gen_1	811	819	PF02991	0.628
LIG_LIR_Nem_3	139	143	PF02991	0.730
LIG_LIR_Nem_3	1443	1447	PF02991	0.512
LIG_LIR_Nem_3	155	160	PF02991	0.504
LIG_LIR_Nem_3	16	22	PF02991	0.682
LIG_LIR_Nem_3	287	291	PF02991	0.393
LIG_LIR_Nem_3	416	422	PF02991	0.558
LIG_LIR_Nem_3	424	428	PF02991	0.535
LIG_LIR_Nem_3	488	494	PF02991	0.592
LIG_LIR_Nem_3	514	520	PF02991	0.598
LIG_LIR_Nem_3	597	603	PF02991	0.511
LIG_LIR_Nem_3	811	817	PF02991	0.624
LIG_MYND_1	1284	1288	PF01753	0.760
LIG_NRBOX	285	291	PF00104	0.407
LIG_PCNA_PIPBox_1	339	348	PF02747	0.504
LIG_PCNA_yPIPBox_3	1191	1205	PF02747	0.728
LIG_PCNA_yPIPBox_3	339	353	PF02747	0.422
LIG_PDZ_Class_2	1687	1692	PF00595	0.550
LIG_Pex14_2	136	140	PF04695	0.734
LIG_Pex14_2	478	482	PF04695	0.631
LIG_Pex14_2	990	994	PF04695	0.588
LIG_PTB_Apo_2	1085	1092	PF02174	0.577
LIG_Rb_pABgroove_1	1024	1032	PF01858	0.560
LIG_SH2_CRK	291	295	PF00017	0.504
LIG_SH2_CRK	376	380	PF00017	0.518
LIG_SH2_CRK	400	404	PF00017	0.499
LIG_SH2_NCK_1	1079	1083	PF00017	0.578
LIG_SH2_NCK_1	1144	1148	PF00017	0.595
LIG_SH2_NCK_1	400	404	PF00017	0.581
LIG_SH2_NCK_1	465	469	PF00017	0.658
LIG_SH2_PTP2	639	642	PF00017	0.257
LIG_SH2_SRC	1177	1180	PF00017	0.490
LIG_SH2_SRC	1644	1647	PF00017	0.612
LIG_SH2_STAP1	1030	1034	PF00017	0.559
LIG_SH2_STAP1	1079	1083	PF00017	0.578
LIG_SH2_STAP1	1144	1148	PF00017	0.630
LIG_SH2_STAP1	350	354	PF00017	0.461
LIG_SH2_STAP1	814	818	PF00017	0.634
LIG_SH2_STAP1	878	882	PF00017	0.642
LIG_SH2_STAP1	985	989	PF00017	0.565
LIG_SH2_STAT3	1123	1126	PF00017	0.652
LIG_SH2_STAT5	1271	1274	PF00017	0.682
LIG_SH2_STAT5	1432	1435	PF00017	0.574
LIG_SH2_STAT5	1448	1451	PF00017	0.450
LIG_SH2_STAT5	1597	1600	PF00017	0.542
LIG_SH2_STAT5	444	447	PF00017	0.646
LIG_SH2_STAT5	527	530	PF00017	0.600
LIG_SH2_STAT5	605	608	PF00017	0.530
LIG_SH2_STAT5	639	642	PF00017	0.407
LIG_SH2_STAT5	648	651	PF00017	0.420
LIG_SH2_STAT5	690	693	PF00017	0.572
LIG_SH2_STAT5	702	705	PF00017	0.516
LIG_SH2_STAT5	894	897	PF00017	0.524
LIG_SH3_2	226	231	PF14604	0.588
LIG_SH3_3	1015	1021	PF00018	0.578
LIG_SH3_3	1282	1288	PF00018	0.764
LIG_SH3_3	1329	1335	PF00018	0.813
LIG_SH3_3	1626	1632	PF00018	0.576
LIG_SH3_3	1650	1656	PF00018	0.542
LIG_SH3_3	223	229	PF00018	0.711
LIG_SH3_3	241	247	PF00018	0.730
LIG_SH3_3	502	508	PF00018	0.620
LIG_SH3_3	520	526	PF00018	0.497
LIG_SH3_3	529	535	PF00018	0.567
LIG_SH3_3	60	66	PF00018	0.662
LIG_SH3_3	813	819	PF00018	0.687
LIG_SH3_CIN85_PxpxPR_1	1127	1132	PF14604	0.654
LIG_SUMO_SIM_anti_2	107	113	PF11976	0.716
LIG_SUMO_SIM_anti_2	1479	1484	PF11976	0.542
LIG_SUMO_SIM_anti_2	1657	1663	PF11976	0.522
LIG_SUMO_SIM_anti_2	615	621	PF11976	0.504
LIG_SUMO_SIM_par_1	1045	1051	PF11976	0.597
LIG_SUMO_SIM_par_1	1249	1254	PF11976	0.714
LIG_SUMO_SIM_par_1	152	158	PF11976	0.635
LIG_SUMO_SIM_par_1	544	550	PF11976	0.471
LIG_SUMO_SIM_par_1	95	102	PF11976	0.740
LIG_SxIP_EBH_1	131	143	PF03271	0.738
LIG_TRAF2_1	1403	1406	PF00917	0.625
LIG_TRAF2_1	851	854	PF00917	0.619
LIG_TRAF2_1	98	101	PF00917	0.741
LIG_TRFH_1	208	212	PF08558	0.707
LIG_TYR_ITIM	1142	1147	PF00017	0.591
LIG_TYR_ITIM	289	294	PF00017	0.407
LIG_TYR_ITIM	423	428	PF00017	0.528
LIG_TYR_ITIM	637	642	PF00017	0.407
LIG_TYR_ITSM	810	817	PF00017	0.622
LIG_UBA3_1	156	163	PF00899	0.635
LIG_UBA3_1	345	353	PF00899	0.621
LIG_UBA3_1	490	496	PF00899	0.598
LIG_UBA3_1	912	920	PF00899	0.574
LIG_WRC_WIRS_1	133	138	PF05994	0.740
LIG_WRC_WIRS_1	1383	1388	PF05994	0.485
LIG_WRC_WIRS_1	1561	1566	PF05994	0.612
LIG_WRC_WIRS_1	432	437	PF05994	0.582
MOD_CDC14_SPxK_1	1206	1209	PF00782	0.774
MOD_CDC14_SPxK_1	1606	1609	PF00782	0.612
MOD_CDC14_SPxK_1	228	231	PF00782	0.663
MOD_CDK_SPxK_1	1054	1060	PF00069	0.666
MOD_CDK_SPxK_1	1203	1209	PF00069	0.772
MOD_CDK_SPxK_1	1603	1609	PF00069	0.612
MOD_CDK_SPxK_1	225	231	PF00069	0.658
MOD_CDK_SPxxK_3	661	668	PF00069	0.646
MOD_CK1_1	1165	1171	PF00069	0.534
MOD_CK1_1	1222	1228	PF00069	0.586
MOD_CK1_1	1262	1268	PF00069	0.727
MOD_CK1_1	1342	1348	PF00069	0.541
MOD_CK1_1	1350	1356	PF00069	0.617
MOD_CK1_1	1375	1381	PF00069	0.645
MOD_CK1_1	1382	1388	PF00069	0.665
MOD_CK1_1	1416	1422	PF00069	0.635
MOD_CK1_1	1468	1474	PF00069	0.542
MOD_CK1_1	152	158	PF00069	0.698
MOD_CK1_1	1676	1682	PF00069	0.612
MOD_CK1_1	171	177	PF00069	0.503
MOD_CK1_1	204	210	PF00069	0.646
MOD_CK1_1	224	230	PF00069	0.670
MOD_CK1_1	237	243	PF00069	0.737
MOD_CK1_1	249	255	PF00069	0.695
MOD_CK1_1	258	264	PF00069	0.680
MOD_CK1_1	36	42	PF00069	0.594
MOD_CK1_1	466	472	PF00069	0.577
MOD_CK1_1	500	506	PF00069	0.613
MOD_CK1_1	544	550	PF00069	0.582
MOD_CK1_1	612	618	PF00069	0.612
MOD_CK1_1	74	80	PF00069	0.739
MOD_CK2_1	1068	1074	PF00069	0.690
MOD_CK2_1	1158	1164	PF00069	0.720
MOD_CK2_1	138	144	PF00069	0.730
MOD_CK2_1	1400	1406	PF00069	0.626
MOD_CK2_1	1468	1474	PF00069	0.542
MOD_CK2_1	1584	1590	PF00069	0.612
MOD_CK2_1	184	190	PF00069	0.681
MOD_CK2_1	22	28	PF00069	0.667
MOD_CK2_1	224	230	PF00069	0.681
MOD_CK2_1	316	322	PF00069	0.495
MOD_CK2_1	402	408	PF00069	0.561
MOD_CK2_1	445	451	PF00069	0.659
MOD_CK2_1	731	737	PF00069	0.678
MOD_CK2_1	739	745	PF00069	0.695
MOD_CK2_1	777	783	PF00069	0.643
MOD_CK2_1	792	798	PF00069	0.685
MOD_CK2_1	809	815	PF00069	0.704
MOD_CK2_1	95	101	PF00069	0.673
MOD_GlcNHglycan	1026	1029	PF01048	0.359
MOD_GlcNHglycan	1042	1045	PF01048	0.289
MOD_GlcNHglycan	1051	1055	PF01048	0.419
MOD_GlcNHglycan	106	109	PF01048	0.443
MOD_GlcNHglycan	1123	1126	PF01048	0.452
MOD_GlcNHglycan	124	127	PF01048	0.504
MOD_GlcNHglycan	1245	1248	PF01048	0.453
MOD_GlcNHglycan	1252	1256	PF01048	0.434
MOD_GlcNHglycan	1261	1264	PF01048	0.457
MOD_GlcNHglycan	1265	1268	PF01048	0.345
MOD_GlcNHglycan	1310	1313	PF01048	0.449
MOD_GlcNHglycan	1344	1347	PF01048	0.422
MOD_GlcNHglycan	1368	1371	PF01048	0.386
MOD_GlcNHglycan	1374	1377	PF01048	0.441
MOD_GlcNHglycan	1398	1401	PF01048	0.336
MOD_GlcNHglycan	1454	1457	PF01048	0.342
MOD_GlcNHglycan	1469	1473	PF01048	0.300
MOD_GlcNHglycan	1575	1578	PF01048	0.326
MOD_GlcNHglycan	1647	1650	PF01048	0.385
MOD_GlcNHglycan	1679	1682	PF01048	0.412
MOD_GlcNHglycan	170	173	PF01048	0.450
MOD_GlcNHglycan	186	189	PF01048	0.564
MOD_GlcNHglycan	197	200	PF01048	0.500
MOD_GlcNHglycan	223	226	PF01048	0.574
MOD_GlcNHglycan	24	27	PF01048	0.501
MOD_GlcNHglycan	259	263	PF01048	0.512
MOD_GlcNHglycan	318	321	PF01048	0.699
MOD_GlcNHglycan	35	38	PF01048	0.398
MOD_GlcNHglycan	508	511	PF01048	0.451
MOD_GlcNHglycan	71	74	PF01048	0.531
MOD_GlcNHglycan	783	786	PF01048	0.519
MOD_GlcNHglycan	898	901	PF01048	0.344
MOD_GlcNHglycan	926	929	PF01048	0.330
MOD_GSK3_1	1050	1057	PF00069	0.647
MOD_GSK3_1	1058	1065	PF00069	0.654
MOD_GSK3_1	1100	1107	PF00069	0.636
MOD_GSK3_1	1156	1163	PF00069	0.712
MOD_GSK3_1	1203	1210	PF00069	0.695
MOD_GSK3_1	1215	1222	PF00069	0.629
MOD_GSK3_1	122	129	PF00069	0.770
MOD_GSK3_1	1251	1258	PF00069	0.668
MOD_GSK3_1	1259	1266	PF00069	0.641
MOD_GSK3_1	1286	1293	PF00069	0.681
MOD_GSK3_1	132	139	PF00069	0.610
MOD_GSK3_1	1375	1382	PF00069	0.678
MOD_GSK3_1	1392	1399	PF00069	0.454
MOD_GSK3_1	1400	1407	PF00069	0.551
MOD_GSK3_1	1416	1423	PF00069	0.635
MOD_GSK3_1	1428	1435	PF00069	0.619
MOD_GSK3_1	1522	1529	PF00069	0.554
MOD_GSK3_1	1540	1547	PF00069	0.412
MOD_GSK3_1	1608	1615	PF00069	0.542
MOD_GSK3_1	1673	1680	PF00069	0.542
MOD_GSK3_1	2	9	PF00069	0.606
MOD_GSK3_1	20	27	PF00069	0.505
MOD_GSK3_1	220	227	PF00069	0.761
MOD_GSK3_1	234	241	PF00069	0.744
MOD_GSK3_1	242	249	PF00069	0.700
MOD_GSK3_1	258	265	PF00069	0.619
MOD_GSK3_1	306	313	PF00069	0.446
MOD_GSK3_1	314	321	PF00069	0.410
MOD_GSK3_1	327	334	PF00069	0.360
MOD_GSK3_1	352	359	PF00069	0.440
MOD_GSK3_1	398	405	PF00069	0.545
MOD_GSK3_1	409	416	PF00069	0.486
MOD_GSK3_1	445	452	PF00069	0.587
MOD_GSK3_1	481	488	PF00069	0.590
MOD_GSK3_1	497	504	PF00069	0.562
MOD_GSK3_1	609	616	PF00069	0.583
MOD_GSK3_1	67	74	PF00069	0.778
MOD_GSK3_1	681	688	PF00069	0.560
MOD_GSK3_1	777	784	PF00069	0.720
MOD_GSK3_1	788	795	PF00069	0.649
MOD_GSK3_1	861	868	PF00069	0.615
MOD_GSK3_1	979	986	PF00069	0.558
MOD_N-GLC_1	1062	1067	PF02516	0.479
MOD_N-GLC_1	1220	1225	PF02516	0.466
MOD_N-GLC_1	1366	1371	PF02516	0.315
MOD_N-GLC_1	1416	1421	PF02516	0.483
MOD_N-GLC_1	1427	1432	PF02516	0.398
MOD_N-GLC_1	1486	1491	PF02516	0.342
MOD_N-GLC_1	201	206	PF02516	0.452
MOD_N-GLC_1	463	468	PF02516	0.326
MOD_N-GLC_1	482	487	PF02516	0.326
MOD_N-GLC_1	67	72	PF02516	0.447
MOD_N-GLC_1	896	901	PF02516	0.341
MOD_N-GLC_2	164	166	PF02516	0.498
MOD_N-GLC_2	54	56	PF02516	0.304
MOD_N-GLC_2	577	579	PF02516	0.423
MOD_NEK2_1	1050	1055	PF00069	0.628
MOD_NEK2_1	1062	1067	PF00069	0.686
MOD_NEK2_1	1121	1126	PF00069	0.648
MOD_NEK2_1	1158	1163	PF00069	0.786
MOD_NEK2_1	1219	1224	PF00069	0.693
MOD_NEK2_1	1230	1235	PF00069	0.760
MOD_NEK2_1	1257	1262	PF00069	0.675
MOD_NEK2_1	1372	1377	PF00069	0.692
MOD_NEK2_1	1404	1409	PF00069	0.573
MOD_NEK2_1	1433	1438	PF00069	0.586
MOD_NEK2_1	1512	1517	PF00069	0.542
MOD_NEK2_1	1573	1578	PF00069	0.515
MOD_NEK2_1	168	173	PF00069	0.629
MOD_NEK2_1	284	289	PF00069	0.532
MOD_NEK2_1	316	321	PF00069	0.496
MOD_NEK2_1	331	336	PF00069	0.407
MOD_NEK2_1	349	354	PF00069	0.449
MOD_NEK2_1	358	363	PF00069	0.504
MOD_NEK2_1	453	458	PF00069	0.663
MOD_NEK2_1	490	495	PF00069	0.640
MOD_NEK2_1	552	557	PF00069	0.463
MOD_NEK2_1	802	807	PF00069	0.647
MOD_NEK2_1	846	851	PF00069	0.672
MOD_NEK2_2	431	436	PF00069	0.559
MOD_PIKK_1	1068	1074	PF00454	0.601
MOD_PIKK_1	1158	1164	PF00454	0.784
MOD_PIKK_1	1271	1277	PF00454	0.558
MOD_PIKK_1	242	248	PF00454	0.732
MOD_PIKK_1	482	488	PF00454	0.540
MOD_PK_1	177	183	PF00069	0.593
MOD_PK_1	582	588	PF00069	0.430
MOD_PKA_1	1584	1590	PF00069	0.612
MOD_PKA_1	1677	1683	PF00069	0.542
MOD_PKA_1	536	542	PF00069	0.451
MOD_PKA_1	7	13	PF00069	0.568
MOD_PKA_2	104	110	PF00069	0.621
MOD_PKA_2	1208	1214	PF00069	0.690
MOD_PKA_2	126	132	PF00069	0.687
MOD_PKA_2	1342	1348	PF00069	0.582
MOD_PKA_2	1433	1439	PF00069	0.500
MOD_PKA_2	166	172	PF00069	0.546
MOD_PKA_2	1677	1683	PF00069	0.542
MOD_PKA_2	184	190	PF00069	0.681
MOD_PKA_2	2	8	PF00069	0.610
MOD_PKA_2	202	208	PF00069	0.610
MOD_PKA_2	284	290	PF00069	0.532
MOD_PKA_2	535	541	PF00069	0.453
MOD_PKA_2	671	677	PF00069	0.606
MOD_PKA_2	788	794	PF00069	0.723
MOD_Plk_1	1058	1064	PF00069	0.744
MOD_Plk_1	1073	1079	PF00069	0.577
MOD_Plk_1	1279	1285	PF00069	0.704
MOD_Plk_1	1366	1372	PF00069	0.496
MOD_Plk_1	1416	1422	PF00069	0.682
MOD_Plk_1	1486	1492	PF00069	0.514
MOD_Plk_1	177	183	PF00069	0.682
MOD_Plk_1	310	316	PF00069	0.363
MOD_Plk_1	482	488	PF00069	0.540
MOD_Plk_1	603	609	PF00069	0.549
MOD_Plk_1	680	686	PF00069	0.534
MOD_Plk_1	731	737	PF00069	0.648
MOD_Plk_1	846	852	PF00069	0.649
MOD_Plk_1	853	859	PF00069	0.595
MOD_Plk_1	878	884	PF00069	0.569
MOD_Plk_2-3	255	261	PF00069	0.666
MOD_Plk_2-3	737	743	PF00069	0.777
MOD_Plk_2-3	792	798	PF00069	0.706
MOD_Plk_4	132	138	PF00069	0.741
MOD_Plk_4	1392	1398	PF00069	0.615
MOD_Plk_4	14	20	PF00069	0.540
MOD_Plk_4	1428	1434	PF00069	0.617
MOD_Plk_4	1500	1506	PF00069	0.612
MOD_Plk_4	152	158	PF00069	0.635
MOD_Plk_4	284	290	PF00069	0.532
MOD_Plk_4	327	333	PF00069	0.400
MOD_Plk_4	371	377	PF00069	0.596
MOD_Plk_4	398	404	PF00069	0.498
MOD_Plk_4	440	446	PF00069	0.606
MOD_Plk_4	485	491	PF00069	0.508
MOD_Plk_4	528	534	PF00069	0.571
MOD_Plk_4	541	547	PF00069	0.512
MOD_Plk_4	621	627	PF00069	0.511
MOD_Plk_4	731	737	PF00069	0.648
MOD_Plk_4	878	884	PF00069	0.569
MOD_Plk_4	974	980	PF00069	0.633
MOD_ProDKin_1	1054	1060	PF00069	0.702
MOD_ProDKin_1	1203	1209	PF00069	0.718
MOD_ProDKin_1	1213	1219	PF00069	0.665
MOD_ProDKin_1	1236	1242	PF00069	0.647
MOD_ProDKin_1	1286	1292	PF00069	0.598
MOD_ProDKin_1	1326	1332	PF00069	0.758
MOD_ProDKin_1	1359	1365	PF00069	0.624
MOD_ProDKin_1	149	155	PF00069	0.722
MOD_ProDKin_1	1591	1597	PF00069	0.536
MOD_ProDKin_1	1603	1609	PF00069	0.542
MOD_ProDKin_1	1628	1634	PF00069	0.576
MOD_ProDKin_1	20	26	PF00069	0.732
MOD_ProDKin_1	225	231	PF00069	0.723
MOD_ProDKin_1	238	244	PF00069	0.528
MOD_ProDKin_1	402	408	PF00069	0.475
MOD_ProDKin_1	501	507	PF00069	0.698
MOD_ProDKin_1	522	528	PF00069	0.569
MOD_ProDKin_1	558	564	PF00069	0.599
MOD_ProDKin_1	59	65	PF00069	0.689
MOD_ProDKin_1	661	667	PF00069	0.647
MOD_ProDKin_1	71	77	PF00069	0.781
MOD_ProDKin_1	745	751	PF00069	0.788
MOD_ProDKin_1	797	803	PF00069	0.712
MOD_ProDKin_1	92	98	PF00069	0.667
MOD_SUMO_for_1	1193	1196	PF00179	0.634
MOD_SUMO_rev_2	347	355	PF00179	0.623
TRG_DiLeu_BaEn_1	1477	1482	PF01217	0.542
TRG_DiLeu_BaEn_1	327	332	PF01217	0.215
TRG_DiLeu_BaEn_1	891	896	PF01217	0.528
TRG_DiLeu_BaEn_4	92	98	PF01217	0.647
TRG_DiLeu_BaLyEn_6	1043	1048	PF01217	0.573
TRG_DiLeu_BaLyEn_6	746	751	PF01217	0.594
TRG_ENDOCYTIC_2	1144	1147	PF00928	0.593
TRG_ENDOCYTIC_2	1177	1180	PF00928	0.617
TRG_ENDOCYTIC_2	1448	1451	PF00928	0.542
TRG_ENDOCYTIC_2	291	294	PF00928	0.407
TRG_ENDOCYTIC_2	400	403	PF00928	0.496
TRG_ENDOCYTIC_2	425	428	PF00928	0.627
TRG_ENDOCYTIC_2	432	435	PF00928	0.536
TRG_ENDOCYTIC_2	444	447	PF00928	0.588
TRG_ENDOCYTIC_2	639	642	PF00928	0.407
TRG_ENDOCYTIC_2	651	654	PF00928	0.561
TRG_ENDOCYTIC_2	814	817	PF00928	0.632
TRG_ENDOCYTIC_2	843	846	PF00928	0.701
TRG_ER_diArg_1	1113	1115	PF00400	0.575
TRG_ER_diArg_1	1201	1203	PF00400	0.686
TRG_ER_diArg_1	1212	1215	PF00400	0.726
TRG_ER_diArg_1	131	133	PF00400	0.663
TRG_ER_diArg_1	160	162	PF00400	0.696
TRG_ER_diArg_1	717	720	PF00400	0.576
TRG_ER_diArg_1	874	876	PF00400	0.595
TRG_ER_diArg_1	906	908	PF00400	0.588
TRG_ER_diArg_1	915	918	PF00400	0.566
TRG_NES_CRM1_1	1006	1020	PF08389	0.575
TRG_Pf-PMV_PEXEL_1	1060	1064	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	273	277	PF00026	0.304
TRG_Pf-PMV_PEXEL_1	89	93	PF00026	0.354

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4I1	Leptomonas seymouri	51%	94%
A0A3S7WWE3	Leishmania donovani	87%	99%
A4HZA0	Leishmania infantum	87%	99%
Q4QCK2	Leishmania major	85%	100%