Separase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Separase

Gene product:

Peptidase C50 separase, putative

Species:

Leishmania mexicana

UniProt:

E9AUU9_LEIMU

TriTrypDb:

LmxM.20.1680

Length:

1279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	8
GO:0043226	organelle	2	8
GO:0043227	membrane-bounded organelle	3	8
GO:0043229	intracellular organelle	3	8
GO:0043231	intracellular membrane-bounded organelle	4	8
GO:0110165	cellular anatomical entity	1	8
GO:0005737	cytoplasm	2	1
GO:0005813	centrosome	3	1
GO:0005815	microtubule organizing center	2	1
GO:0005819	spindle	5	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0072686	mitotic spindle	6	1

Expansion

Sequence features

E9AUU9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUU9

Function

Biological processes
Term	Name	Level	Count
GO:0000280	nuclear division	6	7
GO:0006508	proteolysis	4	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0006996	organelle organization	4	7
GO:0007059	chromosome segregation	2	7
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0016043	cellular component organization	3	7
GO:0019538	protein metabolic process	3	8
GO:0022402	cell cycle process	2	8
GO:0043170	macromolecule metabolic process	3	8
GO:0044238	primary metabolic process	2	8
GO:0048285	organelle fission	5	7
GO:0071704	organic substance metabolic process	2	8
GO:0071840	cellular component organization or biogenesis	2	7
GO:0098813	nuclear chromosome segregation	3	7
GO:1901564	organonitrogen compound metabolic process	3	8
GO:0022414	reproductive process	1	1
GO:0051304	chromosome separation	3	1
GO:0051307	meiotic chromosome separation	3	1
GO:1903046	meiotic cell cycle process	2	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0004175	endopeptidase activity	4	8
GO:0004197	cysteine-type endopeptidase activity	5	8
GO:0008233	peptidase activity	3	8
GO:0008234	cysteine-type peptidase activity	4	8
GO:0016787	hydrolase activity	2	8
GO:0140096	catalytic activity, acting on a protein	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1033	1037	PF00656	0.386
CLV_C14_Caspase3-7	1132	1136	PF00656	0.386
CLV_C14_Caspase3-7	1208	1212	PF00656	0.500
CLV_C14_Caspase3-7	196	200	PF00656	0.502
CLV_C14_Caspase3-7	234	238	PF00656	0.407
CLV_C14_Caspase3-7	609	613	PF00656	0.449
CLV_C14_Caspase3-7	614	618	PF00656	0.418
CLV_C14_Caspase3-7	791	795	PF00656	0.592
CLV_C14_Caspase3-7	822	826	PF00656	0.469
CLV_NRD_NRD_1	1121	1123	PF00675	0.269
CLV_NRD_NRD_1	1245	1247	PF00675	0.414
CLV_NRD_NRD_1	182	184	PF00675	0.461
CLV_NRD_NRD_1	205	207	PF00675	0.556
CLV_NRD_NRD_1	218	220	PF00675	0.338
CLV_NRD_NRD_1	340	342	PF00675	0.507
CLV_NRD_NRD_1	433	435	PF00675	0.438
CLV_NRD_NRD_1	642	644	PF00675	0.461
CLV_NRD_NRD_1	652	654	PF00675	0.572
CLV_NRD_NRD_1	698	700	PF00675	0.427
CLV_NRD_NRD_1	799	801	PF00675	0.415
CLV_PCSK_FUR_1	338	342	PF00082	0.483
CLV_PCSK_FUR_1	640	644	PF00082	0.312
CLV_PCSK_FUR_1	797	801	PF00082	0.466
CLV_PCSK_KEX2_1	1121	1123	PF00082	0.283
CLV_PCSK_KEX2_1	1245	1247	PF00082	0.416
CLV_PCSK_KEX2_1	182	184	PF00082	0.517
CLV_PCSK_KEX2_1	205	207	PF00082	0.559
CLV_PCSK_KEX2_1	218	220	PF00082	0.336
CLV_PCSK_KEX2_1	340	342	PF00082	0.507
CLV_PCSK_KEX2_1	433	435	PF00082	0.438
CLV_PCSK_KEX2_1	642	644	PF00082	0.405
CLV_PCSK_KEX2_1	652	654	PF00082	0.595
CLV_PCSK_KEX2_1	698	700	PF00082	0.427
CLV_PCSK_KEX2_1	799	801	PF00082	0.530
CLV_PCSK_KEX2_1	917	919	PF00082	0.445
CLV_PCSK_PC1ET2_1	917	919	PF00082	0.451
CLV_PCSK_SKI1_1	1121	1125	PF00082	0.272
CLV_PCSK_SKI1_1	1151	1155	PF00082	0.304
CLV_PCSK_SKI1_1	206	210	PF00082	0.547
CLV_PCSK_SKI1_1	218	222	PF00082	0.447
CLV_PCSK_SKI1_1	341	345	PF00082	0.535
CLV_PCSK_SKI1_1	572	576	PF00082	0.513
CLV_PCSK_SKI1_1	605	609	PF00082	0.500
CLV_PCSK_SKI1_1	770	774	PF00082	0.529
CLV_PCSK_SKI1_1	921	925	PF00082	0.518
CLV_Separin_Metazoa	331	335	PF03568	0.434
DEG_APCC_DBOX_1	920	928	PF00400	0.438
DEG_COP1_1	1040	1049	PF00400	0.483
DEG_MDM2_SWIB_1	288	296	PF02201	0.443
DEG_SCF_FBW7_1	442	447	PF00400	0.500
DEG_SCF_FBW7_1	680	687	PF00400	0.316
DEG_SPOP_SBC_1	324	328	PF00917	0.303
DEG_SPOP_SBC_1	576	580	PF00917	0.465
DOC_CDC14_PxL_1	880	888	PF14671	0.424
DOC_CYCLIN_RxL_1	1118	1128	PF00134	0.472
DOC_CYCLIN_RxL_1	203	211	PF00134	0.394
DOC_CYCLIN_RxL_1	216	225	PF00134	0.403
DOC_CYCLIN_RxL_1	917	928	PF00134	0.441
DOC_CYCLIN_yCln2_LP_2	66	72	PF00134	0.390
DOC_MAPK_gen_1	917	924	PF00069	0.403
DOC_MAPK_MEF2A_6	1016	1023	PF00069	0.500
DOC_MAPK_MEF2A_6	394	403	PF00069	0.428
DOC_MAPK_MEF2A_6	90	99	PF00069	0.451
DOC_PP1_RVXF_1	623	630	PF00149	0.562
DOC_PP2B_LxvP_1	97	100	PF13499	0.474
DOC_PP2B_PxIxI_1	398	404	PF00149	0.402
DOC_PP4_FxxP_1	1188	1191	PF00568	0.504
DOC_PP4_FxxP_1	321	324	PF00568	0.453
DOC_SPAK_OSR1_1	544	548	PF12202	0.406
DOC_USP7_MATH_1	1060	1064	PF00917	0.434
DOC_USP7_MATH_1	1197	1201	PF00917	0.500
DOC_USP7_MATH_1	138	142	PF00917	0.673
DOC_USP7_MATH_1	257	261	PF00917	0.506
DOC_USP7_MATH_1	343	347	PF00917	0.710
DOC_USP7_MATH_1	43	47	PF00917	0.488
DOC_USP7_MATH_1	444	448	PF00917	0.604
DOC_USP7_MATH_1	621	625	PF00917	0.618
DOC_USP7_MATH_1	630	634	PF00917	0.498
DOC_USP7_MATH_1	684	688	PF00917	0.553
DOC_USP7_MATH_1	71	75	PF00917	0.518
DOC_USP7_MATH_1	730	734	PF00917	0.410
DOC_USP7_MATH_1	783	787	PF00917	0.530
DOC_USP7_MATH_1	838	842	PF00917	0.448
DOC_USP7_MATH_1	93	97	PF00917	0.356
DOC_USP7_MATH_1	941	945	PF00917	0.520
DOC_USP7_MATH_1	949	953	PF00917	0.498
DOC_WW_Pin1_4	1114	1119	PF00397	0.457
DOC_WW_Pin1_4	1161	1166	PF00397	0.472
DOC_WW_Pin1_4	309	314	PF00397	0.618
DOC_WW_Pin1_4	371	376	PF00397	0.517
DOC_WW_Pin1_4	440	445	PF00397	0.472
DOC_WW_Pin1_4	65	70	PF00397	0.449
DOC_WW_Pin1_4	666	671	PF00397	0.654
DOC_WW_Pin1_4	680	685	PF00397	0.315
DOC_WW_Pin1_4	74	79	PF00397	0.473
DOC_WW_Pin1_4	836	841	PF00397	0.326
DOC_WW_Pin1_4	888	893	PF00397	0.624
LIG_14-3-3_CanoR_1	1178	1188	PF00244	0.599
LIG_14-3-3_CanoR_1	1216	1224	PF00244	0.289
LIG_14-3-3_CanoR_1	149	159	PF00244	0.325
LIG_14-3-3_CanoR_1	182	189	PF00244	0.374
LIG_14-3-3_CanoR_1	205	209	PF00244	0.539
LIG_14-3-3_CanoR_1	42	51	PF00244	0.433
LIG_14-3-3_CanoR_1	544	550	PF00244	0.404
LIG_14-3-3_CanoR_1	572	577	PF00244	0.429
LIG_14-3-3_CanoR_1	603	608	PF00244	0.448
LIG_14-3-3_CanoR_1	631	639	PF00244	0.507
LIG_14-3-3_CanoR_1	643	649	PF00244	0.354
LIG_14-3-3_CanoR_1	818	824	PF00244	0.440
LIG_14-3-3_CanoR_1	894	903	PF00244	0.578
LIG_14-3-3_CanoR_1	904	913	PF00244	0.418
LIG_Actin_WH2_2	5	23	PF00022	0.430
LIG_APCC_ABBA_1	1067	1072	PF00400	0.483
LIG_APCC_ABBAyCdc20_2	1066	1072	PF00400	0.500
LIG_BIR_III_4	825	829	PF00653	0.444
LIG_BRCT_BRCA1_1	248	252	PF00533	0.527
LIG_BRCT_BRCA1_1	311	315	PF00533	0.501
LIG_deltaCOP1_diTrp_1	803	810	PF00928	0.446
LIG_DLG_GKlike_1	1045	1052	PF00625	0.483
LIG_FHA_1	1114	1120	PF00498	0.472
LIG_FHA_1	1165	1171	PF00498	0.472
LIG_FHA_1	15	21	PF00498	0.423
LIG_FHA_1	151	157	PF00498	0.442
LIG_FHA_1	222	228	PF00498	0.411
LIG_FHA_1	509	515	PF00498	0.446
LIG_FHA_1	526	532	PF00498	0.397
LIG_FHA_1	577	583	PF00498	0.492
LIG_FHA_1	632	638	PF00498	0.502
LIG_FHA_1	674	680	PF00498	0.570
LIG_FHA_1	874	880	PF00498	0.439
LIG_FHA_2	1208	1214	PF00498	0.457
LIG_FHA_2	1234	1240	PF00498	0.366
LIG_FHA_2	194	200	PF00498	0.377
LIG_FHA_2	232	238	PF00498	0.428
LIG_FHA_2	478	484	PF00498	0.447
LIG_FHA_2	485	491	PF00498	0.393
LIG_FHA_2	559	565	PF00498	0.347
LIG_FHA_2	604	610	PF00498	0.520
LIG_FHA_2	789	795	PF00498	0.465
LIG_FHA_2	9	15	PF00498	0.510
LIG_GBD_Chelix_1	401	409	PF00786	0.404
LIG_GBD_Chelix_1	569	577	PF00786	0.419
LIG_HCF-1_HBM_1	1017	1020	PF13415	0.500
LIG_HP1_1	93	97	PF01393	0.306
LIG_LIR_Apic_2	1186	1191	PF02991	0.500
LIG_LIR_Apic_2	395	399	PF02991	0.345
LIG_LIR_Apic_2	46	51	PF02991	0.438
LIG_LIR_Apic_2	584	590	PF02991	0.536
LIG_LIR_Apic_2	897	903	PF02991	0.538
LIG_LIR_Gen_1	1017	1027	PF02991	0.457
LIG_LIR_Gen_1	1182	1193	PF02991	0.504
LIG_LIR_Gen_1	1218	1225	PF02991	0.414
LIG_LIR_Gen_1	263	273	PF02991	0.432
LIG_LIR_Gen_1	312	322	PF02991	0.489
LIG_LIR_Nem_3	1017	1023	PF02991	0.457
LIG_LIR_Nem_3	1048	1054	PF02991	0.472
LIG_LIR_Nem_3	1182	1188	PF02991	0.506
LIG_LIR_Nem_3	1218	1224	PF02991	0.434
LIG_LIR_Nem_3	1258	1263	PF02991	0.374
LIG_LIR_Nem_3	178	184	PF02991	0.399
LIG_LIR_Nem_3	187	192	PF02991	0.348
LIG_LIR_Nem_3	263	269	PF02991	0.382
LIG_LIR_Nem_3	312	318	PF02991	0.501
LIG_LIR_Nem_3	38	44	PF02991	0.545
LIG_LIR_Nem_3	404	410	PF02991	0.529
LIG_LIR_Nem_3	516	521	PF02991	0.407
LIG_LIR_Nem_3	958	964	PF02991	0.460
LIG_MYND_1	309	313	PF01753	0.476
LIG_MYND_3	1046	1050	PF01753	0.472
LIG_NRBOX	562	568	PF00104	0.390
LIG_PCNA_yPIPBox_3	259	272	PF02747	0.415
LIG_PCNA_yPIPBox_3	968	978	PF02747	0.453
LIG_Pex14_1	1093	1097	PF04695	0.500
LIG_Pex14_1	806	810	PF04695	0.428
LIG_Pex14_2	288	292	PF04695	0.528
LIG_Pex14_2	518	522	PF04695	0.390
LIG_PTB_Apo_2	980	987	PF02174	0.387
LIG_PTB_Phospho_1	980	986	PF10480	0.377
LIG_Rb_pABgroove_1	7	15	PF01858	0.307
LIG_SH2_CRK	41	45	PF00017	0.512
LIG_SH2_NCK_1	587	591	PF00017	0.559
LIG_SH2_NCK_1	682	686	PF00017	0.361
LIG_SH2_PTP2	396	399	PF00017	0.388
LIG_SH2_PTP2	546	549	PF00017	0.398
LIG_SH2_STAT5	1020	1023	PF00017	0.457
LIG_SH2_STAT5	1051	1054	PF00017	0.534
LIG_SH2_STAT5	1194	1197	PF00017	0.500
LIG_SH2_STAT5	1252	1255	PF00017	0.375
LIG_SH2_STAT5	1266	1269	PF00017	0.434
LIG_SH2_STAT5	396	399	PF00017	0.388
LIG_SH2_STAT5	467	470	PF00017	0.421
LIG_SH2_STAT5	546	549	PF00017	0.482
LIG_SH2_STAT5	682	685	PF00017	0.394
LIG_SH2_STAT5	885	888	PF00017	0.446
LIG_SH3_1	552	558	PF00018	0.384
LIG_SH3_3	1112	1118	PF00018	0.526
LIG_SH3_3	380	386	PF00018	0.454
LIG_SH3_3	552	558	PF00018	0.401
LIG_SH3_3	624	630	PF00018	0.559
LIG_SH3_3	720	726	PF00018	0.568
LIG_SH3_3	92	98	PF00018	0.444
LIG_SUMO_SIM_anti_2	1010	1015	PF11976	0.564
LIG_SUMO_SIM_anti_2	111	118	PF11976	0.458
LIG_SUMO_SIM_anti_2	1167	1173	PF11976	0.483
LIG_SUMO_SIM_anti_2	231	237	PF11976	0.462
LIG_SUMO_SIM_anti_2	480	487	PF11976	0.388
LIG_SUMO_SIM_anti_2	561	567	PF11976	0.300
LIG_SUMO_SIM_anti_2	676	681	PF11976	0.370
LIG_SUMO_SIM_par_1	1010	1015	PF11976	0.465
LIG_SUMO_SIM_par_1	115	122	PF11976	0.522
LIG_SUMO_SIM_par_1	399	404	PF11976	0.461
LIG_SUMO_SIM_par_1	717	722	PF11976	0.438
LIG_TRAF2_1	1037	1040	PF00917	0.386
LIG_TYR_ITIM	39	44	PF00017	0.466
LIG_WRC_WIRS_1	645	650	PF05994	0.357
LIG_WW_3	891	895	PF00397	0.548
MOD_CDK_SPK_2	371	376	PF00069	0.342
MOD_CDK_SPxK_1	888	894	PF00069	0.632
MOD_CDK_SPxxK_3	1114	1121	PF00069	0.328
MOD_CK1_1	1081	1087	PF00069	0.363
MOD_CK1_1	109	115	PF00069	0.510
MOD_CK1_1	1113	1119	PF00069	0.282
MOD_CK1_1	1226	1232	PF00069	0.519
MOD_CK1_1	177	183	PF00069	0.562
MOD_CK1_1	231	237	PF00069	0.418
MOD_CK1_1	243	249	PF00069	0.460
MOD_CK1_1	260	266	PF00069	0.474
MOD_CK1_1	3	9	PF00069	0.460
MOD_CK1_1	347	353	PF00069	0.595
MOD_CK1_1	357	363	PF00069	0.431
MOD_CK1_1	525	531	PF00069	0.349
MOD_CK1_1	662	668	PF00069	0.570
MOD_CK1_1	74	80	PF00069	0.459
MOD_CK1_1	944	950	PF00069	0.594
MOD_CK1_1	966	972	PF00069	0.308
MOD_CK2_1	1122	1128	PF00069	0.313
MOD_CK2_1	1233	1239	PF00069	0.437
MOD_CK2_1	325	331	PF00069	0.560
MOD_CK2_1	558	564	PF00069	0.454
MOD_CK2_1	603	609	PF00069	0.516
MOD_CK2_1	684	690	PF00069	0.605
MOD_GlcNHglycan	1175	1178	PF01048	0.292
MOD_GlcNHglycan	1181	1184	PF01048	0.292
MOD_GlcNHglycan	1195	1198	PF01048	0.171
MOD_GlcNHglycan	184	187	PF01048	0.413
MOD_GlcNHglycan	224	227	PF01048	0.580
MOD_GlcNHglycan	230	233	PF01048	0.481
MOD_GlcNHglycan	259	262	PF01048	0.531
MOD_GlcNHglycan	288	291	PF01048	0.409
MOD_GlcNHglycan	359	362	PF01048	0.427
MOD_GlcNHglycan	447	450	PF01048	0.635
MOD_GlcNHglycan	524	527	PF01048	0.359
MOD_GlcNHglycan	55	58	PF01048	0.418
MOD_GlcNHglycan	707	710	PF01048	0.626
MOD_GlcNHglycan	754	757	PF01048	0.629
MOD_GlcNHglycan	785	788	PF01048	0.490
MOD_GSK3_1	1041	1048	PF00069	0.292
MOD_GSK3_1	105	112	PF00069	0.617
MOD_GSK3_1	1109	1116	PF00069	0.358
MOD_GSK3_1	1193	1200	PF00069	0.351
MOD_GSK3_1	1229	1236	PF00069	0.399
MOD_GSK3_1	1251	1258	PF00069	0.365
MOD_GSK3_1	150	157	PF00069	0.398
MOD_GSK3_1	204	211	PF00069	0.575
MOD_GSK3_1	240	247	PF00069	0.497
MOD_GSK3_1	251	258	PF00069	0.612
MOD_GSK3_1	286	293	PF00069	0.469
MOD_GSK3_1	309	316	PF00069	0.666
MOD_GSK3_1	343	350	PF00069	0.563
MOD_GSK3_1	4	11	PF00069	0.365
MOD_GSK3_1	440	447	PF00069	0.482
MOD_GSK3_1	53	60	PF00069	0.395
MOD_GSK3_1	572	579	PF00069	0.502
MOD_GSK3_1	659	666	PF00069	0.596
MOD_GSK3_1	680	687	PF00069	0.378
MOD_GSK3_1	770	777	PF00069	0.528
MOD_N-GLC_2	656	658	PF02516	0.520
MOD_NEK2_1	1	6	PF00069	0.456
MOD_NEK2_1	115	120	PF00069	0.452
MOD_NEK2_1	1172	1177	PF00069	0.292
MOD_NEK2_1	1179	1184	PF00069	0.292
MOD_NEK2_1	208	213	PF00069	0.417
MOD_NEK2_1	221	226	PF00069	0.374
MOD_NEK2_1	244	249	PF00069	0.534
MOD_NEK2_1	325	330	PF00069	0.555
MOD_NEK2_1	344	349	PF00069	0.494
MOD_NEK2_1	474	479	PF00069	0.452
MOD_NEK2_1	514	519	PF00069	0.460
MOD_NEK2_1	522	527	PF00069	0.390
MOD_NEK2_1	53	58	PF00069	0.383
MOD_NEK2_1	545	550	PF00069	0.547
MOD_NEK2_1	577	582	PF00069	0.576
MOD_NEK2_1	697	702	PF00069	0.379
MOD_NEK2_1	719	724	PF00069	0.375
MOD_NEK2_1	750	755	PF00069	0.477
MOD_NEK2_1	772	777	PF00069	0.545
MOD_NEK2_1	8	13	PF00069	0.418
MOD_NEK2_2	1255	1260	PF00069	0.408
MOD_NEK2_2	912	917	PF00069	0.399
MOD_PIKK_1	1098	1104	PF00454	0.294
MOD_PIKK_1	1122	1128	PF00454	0.302
MOD_PIKK_1	1223	1229	PF00454	0.471
MOD_PIKK_1	347	353	PF00454	0.546
MOD_PIKK_1	426	432	PF00454	0.335
MOD_PIKK_1	558	564	PF00454	0.413
MOD_PIKK_1	57	63	PF00454	0.438
MOD_PIKK_1	684	690	PF00454	0.556
MOD_PIKK_1	763	769	PF00454	0.594
MOD_PKA_1	182	188	PF00069	0.436
MOD_PKA_2	1215	1221	PF00069	0.343
MOD_PKA_2	148	154	PF00069	0.425
MOD_PKA_2	182	188	PF00069	0.371
MOD_PKA_2	193	199	PF00069	0.407
MOD_PKA_2	204	210	PF00069	0.338
MOD_PKA_2	426	432	PF00069	0.401
MOD_PKA_2	630	636	PF00069	0.471
MOD_PKA_2	697	703	PF00069	0.401
MOD_PKA_2	750	756	PF00069	0.499
MOD_Plk_1	1039	1045	PF00069	0.357
MOD_Plk_1	177	183	PF00069	0.438
MOD_Plk_1	942	948	PF00069	0.539
MOD_Plk_1	966	972	PF00069	0.459
MOD_Plk_2-3	1233	1239	PF00069	0.398
MOD_Plk_2-3	130	136	PF00069	0.465
MOD_Plk_4	1110	1116	PF00069	0.193
MOD_Plk_4	1164	1170	PF00069	0.308
MOD_Plk_4	1255	1261	PF00069	0.363
MOD_Plk_4	155	161	PF00069	0.396
MOD_Plk_4	184	190	PF00069	0.384
MOD_Plk_4	208	214	PF00069	0.451
MOD_Plk_4	231	237	PF00069	0.544
MOD_Plk_4	4	10	PF00069	0.366
MOD_Plk_4	545	551	PF00069	0.511
MOD_Plk_4	572	578	PF00069	0.499
MOD_Plk_4	589	595	PF00069	0.377
MOD_Plk_4	603	609	PF00069	0.417
MOD_Plk_4	673	679	PF00069	0.510
MOD_ProDKin_1	1114	1120	PF00069	0.292
MOD_ProDKin_1	1161	1167	PF00069	0.313
MOD_ProDKin_1	309	315	PF00069	0.611
MOD_ProDKin_1	371	377	PF00069	0.514
MOD_ProDKin_1	440	446	PF00069	0.478
MOD_ProDKin_1	65	71	PF00069	0.447
MOD_ProDKin_1	666	672	PF00069	0.643
MOD_ProDKin_1	680	686	PF00069	0.322
MOD_ProDKin_1	74	80	PF00069	0.466
MOD_ProDKin_1	836	842	PF00069	0.320
MOD_ProDKin_1	888	894	PF00069	0.632
TRG_DiLeu_BaEn_1	1017	1022	PF01217	0.328
TRG_DiLeu_BaEn_1	25	30	PF01217	0.400
TRG_DiLeu_BaEn_1	412	417	PF01217	0.397
TRG_DiLeu_BaEn_1	690	695	PF01217	0.475
TRG_DiLeu_BaLyEn_6	1119	1124	PF01217	0.301
TRG_DiLeu_BaLyEn_6	306	311	PF01217	0.467
TRG_DiLeu_BaLyEn_6	363	368	PF01217	0.414
TRG_DiLeu_BaLyEn_6	396	401	PF01217	0.510
TRG_DiLeu_BaLyEn_6	526	531	PF01217	0.390
TRG_DiLeu_BaLyEn_6	549	554	PF01217	0.453
TRG_ENDOCYTIC_2	1020	1023	PF00928	0.292
TRG_ENDOCYTIC_2	1155	1158	PF00928	0.343
TRG_ENDOCYTIC_2	1185	1188	PF00928	0.308
TRG_ENDOCYTIC_2	162	165	PF00928	0.422
TRG_ENDOCYTIC_2	41	44	PF00928	0.501
TRG_ENDOCYTIC_2	546	549	PF00928	0.393
TRG_ENDOCYTIC_2	986	989	PF00928	0.471
TRG_ER_diArg_1	1120	1122	PF00400	0.328
TRG_ER_diArg_1	181	183	PF00400	0.464
TRG_ER_diArg_1	204	206	PF00400	0.556
TRG_ER_diArg_1	217	219	PF00400	0.336
TRG_ER_diArg_1	281	284	PF00400	0.413
TRG_ER_diArg_1	338	341	PF00400	0.483
TRG_ER_diArg_1	433	435	PF00400	0.438
TRG_ER_diArg_1	458	461	PF00400	0.412
TRG_ER_diArg_1	502	505	PF00400	0.469
TRG_ER_diArg_1	639	642	PF00400	0.357
TRG_ER_diArg_1	697	699	PF00400	0.426
TRG_ER_diArg_1	797	800	PF00400	0.472
TRG_Pf-PMV_PEXEL_1	10	14	PF00026	0.436
TRG_Pf-PMV_PEXEL_1	1121	1126	PF00026	0.324
TRG_Pf-PMV_PEXEL_1	762	767	PF00026	0.649
TRG_Pf-PMV_PEXEL_1	921	925	PF00026	0.450
TRG_Pf-PMV_PEXEL_1	987	992	PF00026	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCC3	Leptomonas seymouri	40%	98%
A0A3Q8IDS1	Leishmania donovani	88%	100%
A4HYZ7	Leishmania infantum	88%	100%
C9ZIN0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
E9AIL6	Leishmania braziliensis	76%	100%
Q4QCN4	Leishmania major	88%	100%