Ribosomal protein S11 homolog

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein S11 homolog

Species:

Leishmania mexicana

UniProt:

E9AUU6_LEIMU

TriTrypDb:

LmxM.20.1650 , LmxM.21.1550

Length:

141

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	14
GO:0032991	protein-containing complex	1	15
GO:0043226	organelle	2	15
GO:0043228	non-membrane-bounded organelle	3	15
GO:0043229	intracellular organelle	3	15
GO:0043232	intracellular non-membrane-bounded organelle	4	15
GO:0110165	cellular anatomical entity	1	15
GO:1990904	ribonucleoprotein complex	2	15
GO:0005730	nucleolus	5	1
GO:0005737	cytoplasm	2	1
GO:0015935	small ribosomal subunit	4	1
GO:0022627	cytosolic small ribosomal subunit	5	1
GO:0044391	ribosomal subunit	3	1

Expansion

Sequence features

E9AUU6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUU6

PDB structure(s): 6az1_U

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	15
GO:0006518	peptide metabolic process	4	15
GO:0006807	nitrogen compound metabolic process	2	15
GO:0008152	metabolic process	1	15
GO:0009058	biosynthetic process	2	15
GO:0009059	macromolecule biosynthetic process	4	15
GO:0009987	cellular process	1	15
GO:0019538	protein metabolic process	3	15
GO:0034641	cellular nitrogen compound metabolic process	3	15
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	15
GO:0043043	peptide biosynthetic process	5	15
GO:0043170	macromolecule metabolic process	3	15
GO:0043603	amide metabolic process	3	15
GO:0043604	amide biosynthetic process	4	15
GO:0044237	cellular metabolic process	2	15
GO:0044238	primary metabolic process	2	15
GO:0044249	cellular biosynthetic process	3	15
GO:0044260	obsolete cellular macromolecule metabolic process	3	15
GO:0044271	cellular nitrogen compound biosynthetic process	4	15
GO:0071704	organic substance metabolic process	2	15
GO:1901564	organonitrogen compound metabolic process	3	15
GO:1901566	organonitrogen compound biosynthetic process	4	15
GO:1901576	organic substance biosynthetic process	3	15

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	15
GO:0005198	structural molecule activity	1	15

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	38	40	PF00675	0.305
CLV_NRD_NRD_1	5	7	PF00675	0.670
CLV_NRD_NRD_1	70	72	PF00675	0.290
CLV_PCSK_KEX2_1	70	72	PF00082	0.298
CLV_PCSK_KEX2_1	85	87	PF00082	0.288
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.288
CLV_PCSK_SKI1_1	137	141	PF00082	0.658
DEG_APCC_DBOX_1	70	78	PF00400	0.488
DOC_CKS1_1	25	30	PF01111	0.488
DOC_CYCLIN_yClb1_LxF_4	71	77	PF00134	0.505
DOC_MAPK_gen_1	116	125	PF00069	0.479
DOC_MAPK_gen_1	16	25	PF00069	0.488
DOC_MAPK_gen_1	70	76	PF00069	0.505
DOC_MAPK_gen_1	82	92	PF00069	0.544
DOC_MAPK_MEF2A_6	16	25	PF00069	0.488
DOC_PP4_FxxP_1	25	28	PF00568	0.486
DOC_USP7_MATH_1	42	46	PF00917	0.505
DOC_USP7_UBL2_3	133	137	PF12436	0.559
DOC_USP7_UBL2_3	26	30	PF12436	0.401
DOC_USP7_UBL2_3	7	11	PF12436	0.477
DOC_WW_Pin1_4	24	29	PF00397	0.486
DOC_WW_Pin1_4	92	97	PF00397	0.483
LIG_14-3-3_CanoR_1	86	91	PF00244	0.507
LIG_Actin_WH2_2	40	57	PF00022	0.488
LIG_BRCT_BRCA1_1	94	98	PF00533	0.488
LIG_FHA_1	42	48	PF00498	0.481
LIG_FHA_1	64	70	PF00498	0.564
LIG_LIR_Gen_1	117	126	PF02991	0.485
LIG_LIR_Nem_3	117	123	PF02991	0.481
LIG_SH2_STAP1	17	21	PF00017	0.505
LIG_SH2_STAT5	36	39	PF00017	0.485
LIG_SH2_STAT5	73	76	PF00017	0.488
LIG_SUMO_SIM_par_1	121	127	PF11976	0.527
LIG_TYR_ITIM	118	123	PF00017	0.485
LIG_UBA3_1	53	62	PF00899	0.493
MOD_CDK_SPxK_1	24	30	PF00069	0.583
MOD_CK1_1	127	133	PF00069	0.652
MOD_Cter_Amidation	134	137	PF01082	0.558
MOD_GlcNHglycan	11	14	PF01048	0.288
MOD_GlcNHglycan	129	132	PF01048	0.530
MOD_N-GLC_1	9	14	PF02516	0.288
MOD_NEK2_1	114	119	PF00069	0.488
MOD_NEK2_1	63	68	PF00069	0.480
MOD_PKA_2	15	21	PF00069	0.439
MOD_PKA_2	2	8	PF00069	0.663
MOD_ProDKin_1	24	30	PF00069	0.486
MOD_ProDKin_1	92	98	PF00069	0.483
TRG_ENDOCYTIC_2	120	123	PF00928	0.485
TRG_ENDOCYTIC_2	73	76	PF00928	0.488
TRG_ER_diArg_1	49	52	PF00400	0.488
TRG_ER_diArg_1	69	71	PF00400	0.490
TRG_NLS_Bipartite_1	70	89	PF00514	0.488
TRG_NLS_MonoExtN_4	82	89	PF00514	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCZ8	Leptomonas seymouri	96%	82%
A0A0S4JLC5	Bodo saltans	77%	79%
A0A0S4JN36	Bodo saltans	77%	97%
A0A1D8PN83	Candida albicans (strain SC5314 / ATCC MYA-2876)	61%	91%
A0A1X0NW38	Trypanosomatidae	86%	82%
A0A3R7KSH5	Trypanosoma rangeli	84%	82%
A2SPL1	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	41%	100%
A3CT06	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	37%	100%
A4HC02	Leishmania braziliensis	98%	100%
A4HYZ5	Leishmania infantum	99%	100%
A7I5P8	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	41%	100%
A9A5I6	Nitrosopumilus maritimus (strain SCM1)	33%	100%
B0R665	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	40%	100%
B8GKE2	Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)	40%	100%
C9ZIN6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	84%	81%
D0A131	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	83%	81%
E9AIL3	Leishmania braziliensis	96%	100%
O24786	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	40%	100%
O26120	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	40%	100%
O28363	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	34%	100%
O59426	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	38%	100%
O65569	Arabidopsis thaliana	63%	89%
P0CT73	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	65%	93%
P0CT74	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	65%	93%
P0CX47	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	62%	90%
P0CX48	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	62%	90%
P12741	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	36%	100%
P14042	Methanococcus vannielii	40%	100%
P16181	Arabidopsis thaliana	62%	88%
P17093	Glycine max	65%	89%
P25460	Zea mays	66%	89%
P41115	Xenopus laevis	59%	89%
P42733	Arabidopsis thaliana	65%	89%
P42756	Dunaliella tertiolecta	60%	90%
P52812	Anopheles gambiae	58%	92%
P54036	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	39%	100%
P61270	Macaca fascicularis	60%	89%
P62280	Homo sapiens	60%	89%
P62281	Mus musculus	60%	89%
P62282	Rattus norvegicus	60%	89%
Q0E9B6	Drosophila melanogaster	54%	91%
Q0W1X9	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	42%	100%
Q12ZU2	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	42%	100%
Q18GF8	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	37%	100%
Q292D0	Drosophila pseudoobscura pseudoobscura	56%	91%
Q2FT32	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	42%	100%
Q2NFW6	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	37%	100%
Q3T0V4	Bos taurus	60%	89%
Q46GA4	Methanosarcina barkeri (strain Fusaro / DSM 804)	41%	100%
Q4JB49	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	32%	100%
Q4QCN7	Leishmania major	99%	100%
Q54S90	Dictyostelium discoideum	60%	91%
Q5JDH9	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	38%	100%
Q6L1B8	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	39%	100%
Q6LXE4	Methanococcus maripaludis (strain S2 / LL)	41%	100%
Q6XHX5	Drosophila yakuba	54%	91%
Q74NJ4	Nanoarchaeum equitans (strain Kin4-M)	34%	100%
Q8PV41	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	39%	100%
Q8TRT8	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	40%	100%
Q8TW21	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	39%	100%
Q8U008	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	37%	100%
Q8ZWL3	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	33%	100%
Q975I9	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	37%	100%
Q97BW7	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	36%	100%
Q9HIR8	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	34%	100%
Q9M5M1	Euphorbia esula	64%	89%
Q9TXA6	Leishmania donovani	99%	100%
Q9V1U5	Pyrococcus abyssi (strain GE5 / Orsay)	38%	100%
Q9XSU4	Canis lupus familiaris	60%	89%
Q9YF81	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	35%	100%
V5BHG4	Trypanosoma cruzi	81%	82%