Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AUT9_LEIMU

TriTrypDb:

LmxM.20.1500

Length:

974

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUT9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	416	420	PF00656	0.623
CLV_C14_Caspase3-7	642	646	PF00656	0.393
CLV_C14_Caspase3-7	848	852	PF00656	0.625
CLV_C14_Caspase3-7	894	898	PF00656	0.593
CLV_NRD_NRD_1	154	156	PF00675	0.759
CLV_NRD_NRD_1	332	334	PF00675	0.506
CLV_NRD_NRD_1	538	540	PF00675	0.398
CLV_NRD_NRD_1	718	720	PF00675	0.723
CLV_NRD_NRD_1	863	865	PF00675	0.629
CLV_NRD_NRD_1	873	875	PF00675	0.652
CLV_NRD_NRD_1	960	962	PF00675	0.677
CLV_NRD_NRD_1	971	973	PF00675	0.570
CLV_PCSK_FUR_1	450	454	PF00082	0.422
CLV_PCSK_KEX2_1	154	156	PF00082	0.759
CLV_PCSK_KEX2_1	332	334	PF00082	0.506
CLV_PCSK_KEX2_1	452	454	PF00082	0.576
CLV_PCSK_KEX2_1	718	720	PF00082	0.759
CLV_PCSK_KEX2_1	865	867	PF00082	0.645
CLV_PCSK_KEX2_1	960	962	PF00082	0.620
CLV_PCSK_KEX2_1	971	973	PF00082	0.539
CLV_PCSK_PC1ET2_1	452	454	PF00082	0.427
CLV_PCSK_PC1ET2_1	865	867	PF00082	0.645
CLV_PCSK_PC1ET2_1	960	962	PF00082	0.620
CLV_PCSK_SKI1_1	244	248	PF00082	0.396
CLV_PCSK_SKI1_1	438	442	PF00082	0.362
CLV_PCSK_SKI1_1	62	66	PF00082	0.413
CLV_PCSK_SKI1_1	636	640	PF00082	0.448
CLV_PCSK_SKI1_1	647	651	PF00082	0.399
CLV_PCSK_SKI1_1	676	680	PF00082	0.440
CLV_PCSK_SKI1_1	86	90	PF00082	0.413
CLV_PCSK_SKI1_1	875	879	PF00082	0.673
CLV_PCSK_SKI1_1	961	965	PF00082	0.557
DEG_APCC_DBOX_1	437	445	PF00400	0.357
DEG_COP1_1	467	476	PF00400	0.495
DEG_Nend_Nbox_1	1	3	PF02207	0.453
DEG_SCF_FBW7_2	110	117	PF00400	0.381
DEG_SPOP_SBC_1	258	262	PF00917	0.323
DEG_SPOP_SBC_1	505	509	PF00917	0.445
DOC_CDC14_PxL_1	264	272	PF14671	0.364
DOC_CDC14_PxL_1	431	439	PF14671	0.261
DOC_CKS1_1	111	116	PF01111	0.376
DOC_CKS1_1	797	802	PF01111	0.601
DOC_CYCLIN_RxL_1	435	443	PF00134	0.346
DOC_CYCLIN_RxL_1	633	643	PF00134	0.535
DOC_CYCLIN_RxL_1	83	90	PF00134	0.408
DOC_CYCLIN_RxL_1	872	882	PF00134	0.670
DOC_CYCLIN_yClb1_LxF_4	454	460	PF00134	0.443
DOC_MAPK_DCC_7	86	96	PF00069	0.476
DOC_MAPK_FxFP_2	432	435	PF00069	0.248
DOC_MAPK_gen_1	139	148	PF00069	0.425
DOC_MAPK_gen_1	202	212	PF00069	0.489
DOC_MAPK_gen_1	450	460	PF00069	0.485
DOC_MAPK_gen_1	536	545	PF00069	0.477
DOC_MAPK_gen_1	615	623	PF00069	0.456
DOC_MAPK_gen_1	62	70	PF00069	0.392
DOC_MAPK_gen_1	84	91	PF00069	0.422
DOC_MAPK_MEF2A_6	205	212	PF00069	0.405
DOC_MAPK_MEF2A_6	536	545	PF00069	0.504
DOC_MAPK_NFAT4_5	205	213	PF00069	0.378
DOC_PP1_RVXF_1	242	248	PF00149	0.390
DOC_PP1_RVXF_1	803	810	PF00149	0.577
DOC_PP2B_LxvP_1	252	255	PF13499	0.407
DOC_PP2B_LxvP_1	638	641	PF13499	0.459
DOC_PP2B_LxvP_1	89	92	PF13499	0.475
DOC_PP4_FxxP_1	432	435	PF00568	0.248
DOC_PP4_FxxP_1	544	547	PF00568	0.529
DOC_USP7_MATH_1	102	106	PF00917	0.609
DOC_USP7_MATH_1	142	146	PF00917	0.433
DOC_USP7_MATH_1	229	233	PF00917	0.402
DOC_USP7_MATH_1	259	263	PF00917	0.401
DOC_USP7_MATH_1	344	348	PF00917	0.653
DOC_USP7_MATH_1	367	371	PF00917	0.709
DOC_USP7_MATH_1	411	415	PF00917	0.746
DOC_USP7_MATH_1	488	492	PF00917	0.556
DOC_USP7_MATH_1	496	500	PF00917	0.469
DOC_USP7_MATH_1	505	509	PF00917	0.539
DOC_USP7_MATH_1	526	530	PF00917	0.371
DOC_USP7_MATH_1	656	660	PF00917	0.530
DOC_USP7_MATH_1	701	705	PF00917	0.474
DOC_USP7_MATH_1	717	721	PF00917	0.552
DOC_USP7_MATH_1	834	838	PF00917	0.668
DOC_USP7_MATH_1	859	863	PF00917	0.689
DOC_USP7_MATH_1	886	890	PF00917	0.534
DOC_USP7_MATH_1	912	916	PF00917	0.571
DOC_USP7_MATH_1	940	944	PF00917	0.619
DOC_USP7_MATH_1	955	959	PF00917	0.498
DOC_USP7_MATH_2	641	647	PF00917	0.538
DOC_USP7_UBL2_3	815	819	PF12436	0.650
DOC_USP7_UBL2_3	962	966	PF12436	0.565
DOC_WW_Pin1_4	110	115	PF00397	0.394
DOC_WW_Pin1_4	189	194	PF00397	0.481
DOC_WW_Pin1_4	47	52	PF00397	0.381
DOC_WW_Pin1_4	679	684	PF00397	0.503
DOC_WW_Pin1_4	718	723	PF00397	0.512
DOC_WW_Pin1_4	796	801	PF00397	0.614
DOC_WW_Pin1_4	868	873	PF00397	0.718
DOC_WW_Pin1_4	938	943	PF00397	0.685
LIG_14-3-3_CanoR_1	202	212	PF00244	0.466
LIG_14-3-3_CanoR_1	332	338	PF00244	0.476
LIG_14-3-3_CanoR_1	497	501	PF00244	0.491
LIG_14-3-3_CanoR_1	539	544	PF00244	0.382
LIG_14-3-3_CanoR_1	718	722	PF00244	0.595
LIG_14-3-3_CanoR_1	866	872	PF00244	0.717
LIG_14-3-3_CanoR_1	961	970	PF00244	0.597
LIG_APCC_ABBA_1	396	401	PF00400	0.491
LIG_APCC_ABBA_1	541	546	PF00400	0.413
LIG_APCC_ABBAyCdc20_2	540	546	PF00400	0.414
LIG_BRCT_BRCA1_1	490	494	PF00533	0.513
LIG_eIF4E_1	434	440	PF01652	0.367
LIG_FHA_1	10	16	PF00498	0.503
LIG_FHA_1	20	26	PF00498	0.402
LIG_FHA_1	475	481	PF00498	0.627
LIG_FHA_1	505	511	PF00498	0.574
LIG_FHA_1	693	699	PF00498	0.468
LIG_FHA_1	845	851	PF00498	0.741
LIG_FHA_1	952	958	PF00498	0.576
LIG_FHA_2	318	324	PF00498	0.518
LIG_FHA_2	424	430	PF00498	0.449
LIG_FHA_2	462	468	PF00498	0.363
LIG_FHA_2	615	621	PF00498	0.455
LIG_LIR_Apic_2	429	435	PF02991	0.251
LIG_LIR_Apic_2	542	547	PF02991	0.421
LIG_LIR_Gen_1	105	114	PF02991	0.463
LIG_LIR_Gen_1	16	25	PF02991	0.390
LIG_LIR_Gen_1	499	505	PF02991	0.404
LIG_LIR_Gen_1	52	61	PF02991	0.513
LIG_LIR_Gen_1	588	595	PF02991	0.374
LIG_LIR_Gen_1	66	74	PF02991	0.267
LIG_LIR_Nem_3	105	109	PF02991	0.495
LIG_LIR_Nem_3	16	20	PF02991	0.395
LIG_LIR_Nem_3	388	393	PF02991	0.454
LIG_LIR_Nem_3	499	504	PF02991	0.409
LIG_LIR_Nem_3	52	57	PF02991	0.416
LIG_LIR_Nem_3	588	592	PF02991	0.371
LIG_LIR_Nem_3	66	70	PF02991	0.361
LIG_LYPXL_S_1	433	437	PF13949	0.426
LIG_LYPXL_yS_3	390	393	PF13949	0.417
LIG_LYPXL_yS_3	434	437	PF13949	0.428
LIG_NRBOX	392	398	PF00104	0.562
LIG_NRBOX	436	442	PF00104	0.451
LIG_NRBOX	526	532	PF00104	0.488
LIG_PCNA_yPIPBox_3	524	536	PF02747	0.486
LIG_REV1ctd_RIR_1	335	343	PF16727	0.531
LIG_REV1ctd_RIR_1	457	466	PF16727	0.456
LIG_SH2_CRK	2	6	PF00017	0.401
LIG_SH2_NCK_1	46	50	PF00017	0.397
LIG_SH2_NCK_1	758	762	PF00017	0.464
LIG_SH2_PTP2	67	70	PF00017	0.341
LIG_SH2_SRC	226	229	PF00017	0.254
LIG_SH2_SRC	758	761	PF00017	0.546
LIG_SH2_STAP1	301	305	PF00017	0.380
LIG_SH2_STAT3	664	667	PF00017	0.423
LIG_SH2_STAT5	136	139	PF00017	0.377
LIG_SH2_STAT5	226	229	PF00017	0.254
LIG_SH2_STAT5	436	439	PF00017	0.577
LIG_SH2_STAT5	603	606	PF00017	0.490
LIG_SH2_STAT5	664	667	PF00017	0.423
LIG_SH2_STAT5	67	70	PF00017	0.341
LIG_SH2_STAT5	948	951	PF00017	0.521
LIG_SH3_1	719	725	PF00018	0.649
LIG_SH3_3	104	110	PF00018	0.455
LIG_SH3_3	159	165	PF00018	0.555
LIG_SH3_3	190	196	PF00018	0.483
LIG_SH3_3	719	725	PF00018	0.649
LIG_SH3_3	794	800	PF00018	0.632
LIG_SH3_3	873	879	PF00018	0.748
LIG_SH3_3	939	945	PF00018	0.577
LIG_SUMO_SIM_anti_2	16	22	PF11976	0.459
LIG_SUMO_SIM_anti_2	570	575	PF11976	0.309
LIG_SUMO_SIM_anti_2	66	72	PF11976	0.346
LIG_SUMO_SIM_anti_2	704	710	PF11976	0.462
LIG_SUMO_SIM_anti_2	900	905	PF11976	0.696
LIG_SUMO_SIM_par_1	208	213	PF11976	0.348
LIG_TRAF2_1	487	490	PF00917	0.626
LIG_TRAF2_1	515	518	PF00917	0.482
LIG_TRAF2_1	595	598	PF00917	0.490
LIG_UBA3_1	918	926	PF00899	0.574
LIG_WRC_WIRS_1	334	339	PF05994	0.560
LIG_WW_1	724	727	PF00397	0.667
LIG_WW_3	723	727	PF00397	0.606
LIG_WW_3	968	972	PF00397	0.505
MOD_CDC14_SPxK_1	871	874	PF00782	0.591
MOD_CDK_SPK_2	110	115	PF00069	0.394
MOD_CDK_SPK_2	718	723	PF00069	0.512
MOD_CDK_SPxK_1	868	874	PF00069	0.593
MOD_CDK_SPxxK_3	868	875	PF00069	0.679
MOD_CK1_1	105	111	PF00069	0.497
MOD_CK1_1	150	156	PF00069	0.538
MOD_CK1_1	192	198	PF00069	0.545
MOD_CK1_1	231	237	PF00069	0.458
MOD_CK1_1	342	348	PF00069	0.579
MOD_CK1_1	45	51	PF00069	0.474
MOD_CK1_1	503	509	PF00069	0.535
MOD_CK1_1	682	688	PF00069	0.543
MOD_CK1_1	7	13	PF00069	0.409
MOD_CK1_1	730	736	PF00069	0.768
MOD_CK1_1	855	861	PF00069	0.827
MOD_CK1_1	889	895	PF00069	0.661
MOD_CK1_1	917	923	PF00069	0.679
MOD_CK1_1	934	940	PF00069	0.524
MOD_CK1_1	941	947	PF00069	0.557
MOD_CK1_1	951	957	PF00069	0.537
MOD_CK2_1	317	323	PF00069	0.492
MOD_CK2_1	368	374	PF00069	0.678
MOD_CK2_1	614	620	PF00069	0.441
MOD_CK2_1	701	707	PF00069	0.476
MOD_CK2_1	888	894	PF00069	0.521
MOD_Cter_Amidation	330	333	PF01082	0.469
MOD_GlcNHglycan	158	161	PF01048	0.574
MOD_GlcNHglycan	196	199	PF01048	0.444
MOD_GlcNHglycan	220	223	PF01048	0.418
MOD_GlcNHglycan	231	234	PF01048	0.364
MOD_GlcNHglycan	284	287	PF01048	0.500
MOD_GlcNHglycan	344	347	PF01048	0.597
MOD_GlcNHglycan	403	406	PF01048	0.608
MOD_GlcNHglycan	489	493	PF01048	0.599
MOD_GlcNHglycan	647	650	PF01048	0.465
MOD_GlcNHglycan	667	670	PF01048	0.315
MOD_GlcNHglycan	7	10	PF01048	0.392
MOD_GlcNHglycan	703	706	PF01048	0.470
MOD_GlcNHglycan	729	732	PF01048	0.644
MOD_GlcNHglycan	748	754	PF01048	0.490
MOD_GlcNHglycan	783	786	PF01048	0.534
MOD_GlcNHglycan	832	835	PF01048	0.730
MOD_GlcNHglycan	836	839	PF01048	0.764
MOD_GlcNHglycan	857	860	PF01048	0.706
MOD_GlcNHglycan	914	917	PF01048	0.705
MOD_GlcNHglycan	936	939	PF01048	0.707
MOD_GlcNHglycan	951	954	PF01048	0.546
MOD_GlcNHglycan	957	960	PF01048	0.542
MOD_GSK3_1	142	149	PF00069	0.496
MOD_GSK3_1	228	235	PF00069	0.407
MOD_GSK3_1	278	285	PF00069	0.452
MOD_GSK3_1	301	308	PF00069	0.474
MOD_GSK3_1	385	392	PF00069	0.556
MOD_GSK3_1	496	503	PF00069	0.485
MOD_GSK3_1	5	12	PF00069	0.441
MOD_GSK3_1	639	646	PF00069	0.449
MOD_GSK3_1	830	837	PF00069	0.720
MOD_GSK3_1	840	847	PF00069	0.569
MOD_GSK3_1	855	862	PF00069	0.688
MOD_GSK3_1	864	871	PF00069	0.612
MOD_GSK3_1	884	891	PF00069	0.678
MOD_GSK3_1	930	937	PF00069	0.812
MOD_GSK3_1	951	958	PF00069	0.534
MOD_N-GLC_1	123	128	PF02516	0.416
MOD_N-GLC_1	150	155	PF02516	0.566
MOD_N-GLC_1	55	60	PF02516	0.490
MOD_N-GLC_1	884	889	PF02516	0.535
MOD_N-GLC_1	934	939	PF02516	0.541
MOD_NEK2_1	123	128	PF00069	0.513
MOD_NEK2_1	147	152	PF00069	0.564
MOD_NEK2_1	156	161	PF00069	0.570
MOD_NEK2_1	271	276	PF00069	0.448
MOD_NEK2_1	42	47	PF00069	0.381
MOD_NEK2_1	500	505	PF00069	0.433
MOD_NEK2_1	614	619	PF00069	0.510
MOD_NEK2_2	496	501	PF00069	0.524
MOD_PIKK_1	317	323	PF00454	0.539
MOD_PIKK_1	339	345	PF00454	0.561
MOD_PIKK_1	9	15	PF00454	0.449
MOD_PKA_1	539	545	PF00069	0.384
MOD_PKA_1	864	870	PF00069	0.579
MOD_PKA_1	961	967	PF00069	0.579
MOD_PKA_2	183	189	PF00069	0.413
MOD_PKA_2	496	502	PF00069	0.489
MOD_PKA_2	701	707	PF00069	0.612
MOD_PKA_2	717	723	PF00069	0.598
MOD_PKA_2	727	733	PF00069	0.664
MOD_PKA_2	735	741	PF00069	0.629
MOD_PKA_2	830	836	PF00069	0.631
MOD_PKA_2	855	861	PF00069	0.739
MOD_PKA_2	867	873	PF00069	0.599
MOD_PKB_1	864	872	PF00069	0.649
MOD_Plk_1	123	129	PF00069	0.414
MOD_Plk_1	142	148	PF00069	0.317
MOD_Plk_4	102	108	PF00069	0.500
MOD_Plk_4	123	129	PF00069	0.414
MOD_Plk_4	142	148	PF00069	0.317
MOD_Plk_4	16	22	PF00069	0.555
MOD_Plk_4	266	272	PF00069	0.438
MOD_Plk_4	278	284	PF00069	0.368
MOD_Plk_4	301	307	PF00069	0.483
MOD_Plk_4	333	339	PF00069	0.483
MOD_Plk_4	36	42	PF00069	0.472
MOD_Plk_4	376	382	PF00069	0.627
MOD_Plk_4	496	502	PF00069	0.511
MOD_Plk_4	526	532	PF00069	0.485
MOD_Plk_4	539	545	PF00069	0.535
MOD_Plk_4	914	920	PF00069	0.644
MOD_Plk_4	943	949	PF00069	0.520
MOD_ProDKin_1	110	116	PF00069	0.387
MOD_ProDKin_1	189	195	PF00069	0.478
MOD_ProDKin_1	47	53	PF00069	0.382
MOD_ProDKin_1	679	685	PF00069	0.504
MOD_ProDKin_1	718	724	PF00069	0.514
MOD_ProDKin_1	796	802	PF00069	0.613
MOD_ProDKin_1	868	874	PF00069	0.721
MOD_ProDKin_1	938	944	PF00069	0.683
MOD_SUMO_rev_2	891	901	PF00179	0.696
TRG_DiLeu_BaEn_1	66	71	PF01217	0.345
TRG_DiLeu_BaEn_2	116	122	PF01217	0.340
TRG_DiLeu_BaEn_2	455	461	PF01217	0.449
TRG_DiLeu_BaLyEn_6	435	440	PF01217	0.376
TRG_DiLeu_BaLyEn_6	609	614	PF01217	0.468
TRG_DiLeu_BaLyEn_6	873	878	PF01217	0.680
TRG_ENDOCYTIC_2	2	5	PF00928	0.408
TRG_ENDOCYTIC_2	390	393	PF00928	0.417
TRG_ENDOCYTIC_2	434	437	PF00928	0.361
TRG_ENDOCYTIC_2	67	70	PF00928	0.341
TRG_ER_diArg_1	154	156	PF00400	0.759
TRG_ER_diArg_1	332	334	PF00400	0.506
TRG_ER_diArg_1	717	719	PF00400	0.573
TRG_ER_diArg_1	83	86	PF00400	0.399
TRG_ER_diArg_1	970	972	PF00400	0.696
TRG_NES_CRM1_1	117	131	PF08389	0.319
TRG_NLS_MonoExtC_3	863	868	PF00514	0.538
TRG_NLS_MonoExtN_4	864	869	PF00514	0.542
TRG_Pf-PMV_PEXEL_1	438	442	PF00026	0.362
TRG_Pf-PMV_PEXEL_1	86	90	PF00026	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB01	Leptomonas seymouri	49%	100%
A0A3S5H790	Leishmania donovani	91%	100%
A4HZ05	Leishmania infantum	91%	100%
E9AIK7	Leishmania braziliensis	77%	100%
Q4QCP4	Leishmania major	90%	100%