LeishMANIAdb
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SUZ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
SUZ domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AUT3_LEIMU
TriTrypDb:
LmxM.20.1440
Length:
145

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUT3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUT3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 100 102 PF00675 0.584
CLV_NRD_NRD_1 133 135 PF00675 0.643
CLV_NRD_NRD_1 39 41 PF00675 0.593
CLV_NRD_NRD_1 48 50 PF00675 0.665
CLV_PCSK_KEX2_1 100 102 PF00082 0.511
CLV_PCSK_KEX2_1 132 134 PF00082 0.643
CLV_PCSK_KEX2_1 82 84 PF00082 0.679
CLV_PCSK_PC1ET2_1 82 84 PF00082 0.679
CLV_PCSK_SKI1_1 82 86 PF00082 0.604
DEG_SIAH_1 113 121 PF03145 0.682
DOC_MAPK_gen_1 100 109 PF00069 0.553
DOC_USP7_MATH_1 42 46 PF00917 0.662
DOC_WW_Pin1_4 18 23 PF00397 0.753
LIG_14-3-3_CanoR_1 83 91 PF00244 0.634
LIG_BIR_II_1 1 5 PF00653 0.775
LIG_FHA_1 121 127 PF00498 0.653
LIG_FHA_1 19 25 PF00498 0.726
LIG_FHA_1 30 36 PF00498 0.696
LIG_FHA_1 83 89 PF00498 0.526
LIG_FHA_2 21 27 PF00498 0.694
LIG_GBD_Chelix_1 68 76 PF00786 0.649
LIG_SH3_3 111 117 PF00018 0.714
LIG_SH3_3 59 65 PF00018 0.729
LIG_TRAF2_1 10 13 PF00917 0.628
LIG_TRAF2_1 53 56 PF00917 0.759
LIG_TRAF2_1 77 80 PF00917 0.609
LIG_TRAF2_1 93 96 PF00917 0.622
LIG_UBA3_1 72 81 PF00899 0.670
LIG_WW_3 46 50 PF00397 0.699
MOD_CK2_1 20 26 PF00069 0.700
MOD_CK2_1 72 78 PF00069 0.570
MOD_GlcNHglycan 1 4 PF01048 0.768
MOD_GlcNHglycan 91 94 PF01048 0.680
MOD_GSK3_1 11 18 PF00069 0.603
MOD_GSK3_1 64 71 PF00069 0.632
MOD_N-GLC_1 109 114 PF02516 0.648
MOD_NEK2_1 72 77 PF00069 0.685
MOD_PIKK_1 91 97 PF00454 0.665
MOD_PKA_1 82 88 PF00069 0.438
MOD_PKA_2 82 88 PF00069 0.438
MOD_Plk_1 127 133 PF00069 0.571
MOD_Plk_4 120 126 PF00069 0.690
MOD_Plk_4 20 26 PF00069 0.597
MOD_Plk_4 64 70 PF00069 0.641
MOD_ProDKin_1 18 24 PF00069 0.751
MOD_SUMO_rev_2 75 84 PF00179 0.610
TRG_ER_diArg_1 131 134 PF00400 0.639
TRG_ER_diArg_1 99 101 PF00400 0.633
TRG_NLS_MonoCore_2 39 44 PF00514 0.606
TRG_NLS_MonoExtN_4 37 44 PF00514 0.603

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PD35 Leptomonas seymouri 70% 100%
A0A0S4ISW9 Bodo saltans 37% 74%
A0A1X0NW52 Trypanosomatidae 43% 78%
A0A3R7N8A8 Trypanosoma rangeli 40% 81%
A0A3S7WW97 Leishmania donovani 95% 100%
A4HYY7 Leishmania infantum 95% 100%
C9ZIJ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 45% 86%
E9AIK1 Leishmania braziliensis 82% 100%
Q4QCQ0 Leishmania major 95% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS