by homology
Contact email: avilan@ula.ve
Publication title: Plasminogen binding proteins in secreted membrane vesicles of Leishmania mexicana
Publication 1st author(s): Figuera
Publication Identifier(s): 23178693
Host organism: -1
Interaction detection method(s): enzymatic linked imunosorbent assay
Interaction type: direct interaction
Identification method participant A: identification by antibody
Identification method participant B: identification by antibody
ID(s) interactor A: E9AUS1
ID(s) interactor B: P00747
Taxid interactor A: Leishmania mexicana
Taxid interactor B: Homo sapiens
Biological role(s) interactor A: unspecified role
Biological role(s) interactor B: unspecified role
Experimental role(s) interactor A: bait
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 2 |
| Forrest at al. (metacyclic) | no | yes: 5 |
| Forrest at al. (procyclic) | no | yes: 7 |
| Silverman et al. | no | yes: 1 |
| Pissara et al. | yes | yes: 24 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 12 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 27 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 44 |
| NetGPI | no | yes: 0, no: 44 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005654 | nucleoplasm | 2 | 1 |
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0031974 | membrane-enclosed lumen | 2 | 1 |
| GO:0031981 | nuclear lumen | 5 | 1 |
| GO:0032838 | plasma membrane bounded cell projection cytoplasm | 4 | 1 |
| GO:0043233 | organelle lumen | 3 | 1 |
| GO:0070013 | intracellular organelle lumen | 4 | 1 |
| GO:0097014 | ciliary plasm | 5 | 1 |
| GO:0097542 | ciliary tip | 2 | 1 |
| GO:0099568 | cytoplasmic region | 3 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 3 |
| GO:0016020 | membrane | 2 | 2 |
| GO:0020018 | ciliary pocket membrane | 6 | 1 |
| GO:0031090 | organelle membrane | 3 | 2 |
| GO:0031253 | cell projection membrane | 4 | 2 |
| GO:0060170 | ciliary membrane | 5 | 2 |
| GO:0098588 | bounding membrane of organelle | 4 | 2 |
| GO:0098590 | plasma membrane region | 3 | 2 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0001539 | cilium or flagellum-dependent cell motility | 3 | 1 |
| GO:0009987 | cellular process | 1 | 2 |
| GO:0048870 | cell motility | 2 | 1 |
| GO:0060285 | cilium-dependent cell motility | 4 | 1 |
| GO:0006996 | organelle organization | 4 | 1 |
| GO:0016043 | cellular component organization | 3 | 1 |
| GO:0022607 | cellular component assembly | 4 | 1 |
| GO:0030030 | cell projection organization | 4 | 1 |
| GO:0030031 | cell projection assembly | 5 | 1 |
| GO:0044000 | movement in host | 4 | 1 |
| GO:0044403 | biological process involved in symbiotic interaction | 2 | 1 |
| GO:0044409 | entry into host | 5 | 1 |
| GO:0044419 | biological process involved in interspecies interaction between organisms | 1 | 1 |
| GO:0044782 | cilium organization | 5 | 1 |
| GO:0051701 | biological process involved in interaction with host | 3 | 1 |
| GO:0060271 | cilium assembly | 6 | 1 |
| GO:0070925 | organelle assembly | 5 | 1 |
| GO:0071840 | cellular component organization or biogenesis | 2 | 1 |
| GO:0120031 | plasma membrane bounded cell projection assembly | 6 | 1 |
| GO:0120036 | plasma membrane bounded cell projection organization | 5 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_PCSK_KEX2_1 | 54 | 56 | PF00082 | 0.435 |
| CLV_PCSK_PC1ET2_1 | 54 | 56 | PF00082 | 0.405 |
| CLV_PCSK_SKI1_1 | 131 | 135 | PF00082 | 0.754 |
| DOC_MAPK_gen_1 | 54 | 62 | PF00069 | 0.442 |
| DOC_MAPK_MEF2A_6 | 55 | 64 | PF00069 | 0.439 |
| DOC_PP1_RVXF_1 | 59 | 65 | PF00149 | 0.388 |
| DOC_USP7_UBL2_3 | 123 | 127 | PF12436 | 0.644 |
| DOC_USP7_UBL2_3 | 130 | 134 | PF12436 | 0.672 |
| LIG_14-3-3_CanoR_1 | 38 | 47 | PF00244 | 0.234 |
| LIG_APCC_ABBA_1 | 26 | 31 | PF00400 | 0.474 |
| LIG_APCC_ABBAyCdc20_2 | 25 | 31 | PF00400 | 0.258 |
| LIG_BRCT_BRCA1_1 | 45 | 49 | PF00533 | 0.247 |
| LIG_LIR_Apic_2 | 11 | 17 | PF02991 | 0.711 |
| LIG_LIR_Nem_3 | 46 | 50 | PF02991 | 0.412 |
| LIG_PCNA_yPIPBox_3 | 110 | 123 | PF02747 | 0.502 |
| LIG_PCNA_yPIPBox_3 | 32 | 40 | PF02747 | 0.429 |
| LIG_SH2_CRK | 14 | 18 | PF00017 | 0.676 |
| LIG_SH2_STAT5 | 78 | 81 | PF00017 | 0.407 |
| MOD_CK1_1 | 15 | 21 | PF00069 | 0.550 |
| MOD_GlcNHglycan | 14 | 17 | PF01048 | 0.559 |
| MOD_GSK3_1 | 39 | 46 | PF00069 | 0.386 |
| MOD_N-GLC_1 | 43 | 48 | PF02516 | 0.379 |
| MOD_N-GLC_2 | 51 | 53 | PF02516 | 0.247 |
| MOD_NEK2_1 | 12 | 17 | PF00069 | 0.642 |
| MOD_NEK2_1 | 146 | 151 | PF00069 | 0.532 |
| MOD_NEK2_1 | 74 | 79 | PF00069 | 0.376 |
| MOD_NMyristoyl | 1 | 7 | PF02799 | 0.659 |
| MOD_PKA_2 | 12 | 18 | PF00069 | 0.669 |
| MOD_Plk_4 | 108 | 114 | PF00069 | 0.215 |
| MOD_Plk_4 | 74 | 80 | PF00069 | 0.360 |
| MOD_Plk_4 | 88 | 94 | PF00069 | 0.348 |
| MOD_SUMO_rev_2 | 124 | 133 | PF00179 | 0.710 |
| MOD_SUMO_rev_2 | 46 | 56 | PF00179 | 0.509 |
| TRG_DiLeu_BaEn_1 | 31 | 36 | PF01217 | 0.309 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P6Y3 | Leptomonas seymouri | 43% | 100% |
| A0A0N1HYV4 | Leptomonas seymouri | 42% | 100% |
| A0A0N1I5S6 | Leptomonas seymouri | 69% | 98% |
| A0A0N1PCZ0 | Leptomonas seymouri | 42% | 100% |
| A0A0N1PE11 | Leptomonas seymouri | 36% | 100% |
| A0A1X0NW79 | Trypanosomatidae | 46% | 76% |
| A0A1X0NW95 | Trypanosomatidae | 43% | 100% |
| A0A1X0NWV3 | Trypanosomatidae | 46% | 100% |
| A0A1X0NXT9 | Trypanosomatidae | 36% | 100% |
| A0A1X0NYV3 | Trypanosomatidae | 41% | 100% |
| A0A3Q8I9V9 | Leishmania donovani | 41% | 100% |
| A0A3Q8IBM6 | Leishmania donovani | 31% | 100% |
| A0A3Q8IDP8 | Leishmania donovani | 92% | 100% |
| A0A3Q8IKN9 | Leishmania donovani | 44% | 100% |
| A0A3R7MB04 | Trypanosoma rangeli | 39% | 100% |
| A0A3R7MWC6 | Trypanosoma rangeli | 41% | 100% |
| A0A3S7WW23 | Leishmania donovani | 38% | 100% |
| A0A3S7WZ86 | Leishmania donovani | 34% | 100% |
| A0A422MSY8 | Trypanosoma rangeli | 40% | 90% |
| A0A422MSZ3 | Trypanosoma rangeli | 42% | 100% |
| A0A422MUY0 | Trypanosoma rangeli | 49% | 100% |
| A4H7N9 | Leishmania braziliensis | 45% | 100% |
| A4H7P0 | Leishmania braziliensis | 45% | 100% |
| A4HEG7 | Leishmania braziliensis | 36% | 100% |
| A4HW29 | Leishmania infantum | 41% | 100% |
| A4HYW6 | Leishmania infantum | 31% | 100% |
| A4HYX1 | Leishmania infantum | 92% | 100% |
| A4HYX3 | Leishmania infantum | 38% | 100% |
| A4HYX4 | Leishmania infantum | 44% | 100% |
| A4I1M3 | Leishmania infantum | 34% | 100% |
| E9AII3 | Leishmania braziliensis | 79% | 100% |
| E9AII5 | Leishmania braziliensis | 39% | 100% |
| E9AII6 | Leishmania braziliensis | 44% | 100% |
| E9APT0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 41% | 100% |
| E9AUS0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 38% | 100% |
| E9AUS1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 44% | 100% |
| E9AXQ7 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 33% | 100% |
| P84150 | Leishmania major | 34% | 100% |
| Q4Q9R4 | Leishmania major | 35% | 100% |
| Q4QFP8 | Leishmania major | 41% | 100% |
| Q5SDH3 | Leishmania major | 91% | 100% |
| Q5SDH4 | Leishmania major | 38% | 100% |
| Q5SDH5 | Leishmania major | 47% | 100% |