Protein YIF1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Protein YIF1

Gene product:

protein transport protein YIF1, putative

Species:

Leishmania mexicana

UniProt:

E9AUQ3_LEIMU

TriTrypDb:

LmxM.20.1140

Length:

320

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0000139	Golgi membrane	5	11
GO:0005789	endoplasmic reticulum membrane	4	12
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	5	12
GO:0016020	membrane	2	12
GO:0031090	organelle membrane	3	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0098588	bounding membrane of organelle	4	11
GO:0110165	cellular anatomical entity	1	12
GO:0030134	COPII-coated ER to Golgi transport vesicle	8	1
GO:0030135	coated vesicle	7	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0097708	intracellular vesicle	5	1

Expansion

Sequence features

E9AUQ3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUQ3

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	12
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	4	12
GO:0008104	protein localization	4	12
GO:0009987	cellular process	1	12
GO:0015031	protein transport	4	12
GO:0016192	vesicle-mediated transport	4	12
GO:0033036	macromolecule localization	2	12
GO:0045184	establishment of protein localization	3	12
GO:0046907	intracellular transport	3	12
GO:0048193	Golgi vesicle transport	5	12
GO:0051179	localization	1	12
GO:0051234	establishment of localization	2	12
GO:0051641	cellular localization	2	12
GO:0051649	establishment of localization in cell	3	12
GO:0070727	cellular macromolecule localization	3	12
GO:0071702	organic substance transport	4	12
GO:0071705	nitrogen compound transport	4	12

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	81	83	PF00675	0.239
CLV_NRD_NRD_1	96	98	PF00675	0.249
CLV_PCSK_KEX2_1	81	83	PF00082	0.238
CLV_PCSK_PC1ET2_1	81	83	PF00082	0.243
CLV_PCSK_SKI1_1	242	246	PF00082	0.279
DEG_Nend_UBRbox_3	1	3	PF02207	0.663
DOC_CDC14_PxL_1	86	94	PF14671	0.391
DOC_CKS1_1	1	6	PF01111	0.628
DOC_MAPK_gen_1	81	89	PF00069	0.409
DOC_MAPK_MEF2A_6	242	250	PF00069	0.244
DOC_MAPK_MEF2A_6	81	89	PF00069	0.420
DOC_MAPK_NFAT4_5	82	90	PF00069	0.455
DOC_PP2B_LxvP_1	167	170	PF13499	0.409
DOC_PP2B_LxvP_1	225	228	PF13499	0.424
DOC_PP2B_LxvP_1	87	90	PF13499	0.513
DOC_PP4_FxxP_1	152	155	PF00568	0.455
DOC_USP7_MATH_1	153	157	PF00917	0.517
DOC_USP7_MATH_1	170	174	PF00917	0.420
DOC_USP7_MATH_1	190	194	PF00917	0.255
DOC_USP7_UBL2_3	94	98	PF12436	0.513
DOC_WW_Pin1_4	126	131	PF00397	0.457
DOC_WW_Pin1_4	135	140	PF00397	0.453
DOC_WW_Pin1_4	16	21	PF00397	0.658
DOC_WW_Pin1_4	186	191	PF00397	0.313
DOC_WW_Pin1_4	291	296	PF00397	0.507
DOC_WW_Pin1_4	3	8	PF00397	0.642
DOC_WW_Pin1_4	96	101	PF00397	0.519
LIG_14-3-3_CanoR_1	298	303	PF00244	0.565
LIG_Actin_WH2_2	205	220	PF00022	0.287
LIG_BRCT_BRCA1_1	148	152	PF00533	0.373
LIG_BRCT_BRCA1_1	262	266	PF00533	0.389
LIG_eIF4E_1	79	85	PF01652	0.476
LIG_FHA_1	174	180	PF00498	0.271
LIG_FHA_1	189	195	PF00498	0.220
LIG_FHA_1	200	206	PF00498	0.270
LIG_FHA_1	276	282	PF00498	0.425
LIG_FHA_1	4	10	PF00498	0.691
LIG_FHA_1	91	97	PF00498	0.517
LIG_LIR_Apic_2	149	155	PF02991	0.449
LIG_LIR_Gen_1	176	185	PF02991	0.245
LIG_LIR_Gen_1	297	307	PF02991	0.446
LIG_LIR_Nem_3	132	137	PF02991	0.494
LIG_LIR_Nem_3	165	171	PF02991	0.413
LIG_LIR_Nem_3	176	180	PF02991	0.244
LIG_LIR_Nem_3	259	265	PF02991	0.253
LIG_LIR_Nem_3	275	279	PF02991	0.296
LIG_LYPXL_S_1	133	137	PF13949	0.177
LIG_LYPXL_yS_3	134	137	PF13949	0.377
LIG_PCNA_yPIPBox_3	229	242	PF02747	0.530
LIG_REV1ctd_RIR_1	24	31	PF16727	0.634
LIG_REV1ctd_RIR_1	274	284	PF16727	0.303
LIG_SH2_CRK	222	226	PF00017	0.265
LIG_SH2_CRK	241	245	PF00017	0.244
LIG_SH2_CRK	262	266	PF00017	0.389
LIG_SH2_CRK	269	273	PF00017	0.389
LIG_SH2_PTP2	168	171	PF00017	0.277
LIG_SH2_PTP2	177	180	PF00017	0.198
LIG_SH2_PTP2	243	246	PF00017	0.278
LIG_SH2_STAP1	222	226	PF00017	0.450
LIG_SH2_STAP1	269	273	PF00017	0.409
LIG_SH2_STAP1	300	304	PF00017	0.183
LIG_SH2_STAT5	168	171	PF00017	0.244
LIG_SH2_STAT5	177	180	PF00017	0.244
LIG_SH2_STAT5	183	186	PF00017	0.244
LIG_SH2_STAT5	243	246	PF00017	0.244
LIG_SH2_STAT5	300	303	PF00017	0.311
LIG_SH2_STAT5	72	75	PF00017	0.455
LIG_SH2_STAT5	79	82	PF00017	0.462
LIG_SH2_STAT5	95	98	PF00017	0.517
LIG_SH3_3	1	7	PF00018	0.628
LIG_SH3_3	152	158	PF00018	0.481
LIG_SH3_3	225	231	PF00018	0.451
LIG_SUMO_SIM_anti_2	213	218	PF11976	0.337
LIG_SUMO_SIM_par_1	83	88	PF11976	0.513
LIG_TYR_ITIM	175	180	PF00017	0.244
LIG_UBA3_1	235	242	PF00899	0.333
LIG_UBA3_1	85	94	PF00899	0.508
MOD_CDK_SPK_2	291	296	PF00069	0.338
MOD_CDK_SPxxK_3	291	298	PF00069	0.338
MOD_CK1_1	129	135	PF00069	0.483
MOD_CK1_1	138	144	PF00069	0.447
MOD_CK1_1	173	179	PF00069	0.389
MOD_CK1_1	189	195	PF00069	0.287
MOD_CK1_1	198	204	PF00069	0.300
MOD_CK1_1	21	27	PF00069	0.701
MOD_CK1_1	275	281	PF00069	0.406
MOD_CK1_1	294	300	PF00069	0.567
MOD_GlcNHglycan	109	112	PF01048	0.214
MOD_GlcNHglycan	16	19	PF01048	0.569
MOD_GlcNHglycan	20	23	PF01048	0.492
MOD_GlcNHglycan	262	265	PF01048	0.371
MOD_GSK3_1	102	109	PF00069	0.508
MOD_GSK3_1	14	21	PF00069	0.672
MOD_GSK3_1	186	193	PF00069	0.315
MOD_GSK3_1	195	202	PF00069	0.266
MOD_GSK3_1	256	263	PF00069	0.295
MOD_GSK3_1	294	301	PF00069	0.515
MOD_NEK2_1	107	112	PF00069	0.567
MOD_NEK2_1	123	128	PF00069	0.368
MOD_NEK2_1	199	204	PF00069	0.256
MOD_NEK2_1	272	277	PF00069	0.327
MOD_NEK2_1	39	44	PF00069	0.491
MOD_PIKK_1	250	256	PF00454	0.308
MOD_PKB_1	296	304	PF00069	0.455
MOD_Plk_1	75	81	PF00069	0.513
MOD_Plk_4	129	135	PF00069	0.531
MOD_Plk_4	138	144	PF00069	0.364
MOD_Plk_4	170	176	PF00069	0.324
MOD_Plk_4	195	201	PF00069	0.282
MOD_Plk_4	272	278	PF00069	0.329
MOD_Plk_4	298	304	PF00069	0.419
MOD_Plk_4	75	81	PF00069	0.464
MOD_ProDKin_1	126	132	PF00069	0.457
MOD_ProDKin_1	135	141	PF00069	0.491
MOD_ProDKin_1	16	22	PF00069	0.660
MOD_ProDKin_1	186	192	PF00069	0.313
MOD_ProDKin_1	291	297	PF00069	0.507
MOD_ProDKin_1	3	9	PF00069	0.643
MOD_ProDKin_1	96	102	PF00069	0.519
TRG_DiLeu_BaLyEn_6	228	233	PF01217	0.455
TRG_DiLeu_BaLyEn_6	315	320	PF01217	0.414
TRG_ENDOCYTIC_2	134	137	PF00928	0.382
TRG_ENDOCYTIC_2	168	171	PF00928	0.244
TRG_ENDOCYTIC_2	177	180	PF00928	0.244
TRG_ENDOCYTIC_2	222	225	PF00928	0.265
TRG_ENDOCYTIC_2	241	244	PF00928	0.244
TRG_ENDOCYTIC_2	262	265	PF00928	0.268
TRG_ENDOCYTIC_2	269	272	PF00928	0.233
TRG_ENDOCYTIC_2	300	303	PF00928	0.144
TRG_ENDOCYTIC_2	62	65	PF00928	0.425
TRG_ENDOCYTIC_2	72	75	PF00928	0.389
TRG_ER_diArg_1	295	298	PF00400	0.455
TRG_Pf-PMV_PEXEL_1	280	285	PF00026	0.185

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEI6	Leptomonas seymouri	61%	99%
A0A0S4KG55	Bodo saltans	34%	100%
A0A1X0NW97	Trypanosomatidae	38%	100%
A0A3Q8IDN8	Leishmania donovani	94%	100%
A0A3R7RL55	Trypanosoma rangeli	35%	100%
A4HYV6	Leishmania infantum	94%	100%
C9ZID7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
E9AIG3	Leishmania braziliensis	85%	100%
Q4FZQ0	Xenopus laevis	23%	100%
Q4QCT2	Leishmania major	92%	100%
Q5U3G6	Danio rerio	26%	100%
Q6GN58	Xenopus laevis	22%	100%
Q6P301	Xenopus tropicalis	23%	100%
Q6PC24	Danio rerio	26%	100%
Q91XB7	Mus musculus	27%	100%
V5C052	Trypanosoma cruzi	38%	100%