LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9AUP6_LEIMU
TriTrypDb:
LmxM.20.1070
Length:
276

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUP6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUP6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 113 115 PF00675 0.636
CLV_NRD_NRD_1 160 162 PF00675 0.718
CLV_NRD_NRD_1 167 169 PF00675 0.674
CLV_NRD_NRD_1 183 185 PF00675 0.655
CLV_NRD_NRD_1 198 200 PF00675 0.601
CLV_NRD_NRD_1 207 209 PF00675 0.692
CLV_NRD_NRD_1 228 230 PF00675 0.642
CLV_NRD_NRD_1 233 235 PF00675 0.674
CLV_NRD_NRD_1 83 85 PF00675 0.571
CLV_NRD_NRD_1 97 99 PF00675 0.518
CLV_PCSK_KEX2_1 113 115 PF00082 0.636
CLV_PCSK_KEX2_1 158 160 PF00082 0.716
CLV_PCSK_KEX2_1 167 169 PF00082 0.643
CLV_PCSK_KEX2_1 182 184 PF00082 0.672
CLV_PCSK_KEX2_1 207 209 PF00082 0.706
CLV_PCSK_KEX2_1 233 235 PF00082 0.665
CLV_PCSK_KEX2_1 262 264 PF00082 0.694
CLV_PCSK_KEX2_1 83 85 PF00082 0.534
CLV_PCSK_KEX2_1 97 99 PF00082 0.555
CLV_PCSK_PC1ET2_1 158 160 PF00082 0.716
CLV_PCSK_PC1ET2_1 262 264 PF00082 0.694
CLV_PCSK_PC1ET2_1 83 85 PF00082 0.519
CLV_PCSK_PC7_1 229 235 PF00082 0.539
CLV_PCSK_PC7_1 79 85 PF00082 0.509
CLV_PCSK_SKI1_1 155 159 PF00082 0.718
CLV_PCSK_SKI1_1 161 165 PF00082 0.647
CLV_PCSK_SKI1_1 211 215 PF00082 0.551
CLV_PCSK_SKI1_1 262 266 PF00082 0.498
CLV_PCSK_SKI1_1 84 88 PF00082 0.593
DEG_Nend_UBRbox_3 1 3 PF02207 0.649
DOC_CKS1_1 163 168 PF01111 0.560
DOC_CKS1_1 47 52 PF01111 0.617
DOC_CYCLIN_yClb1_LxF_4 34 40 PF00134 0.492
DOC_MAPK_gen_1 30 39 PF00069 0.597
DOC_PP2B_LxvP_1 122 125 PF13499 0.648
DOC_PP4_FxxP_1 33 36 PF00568 0.626
DOC_USP7_MATH_1 10 14 PF00917 0.522
DOC_USP7_MATH_1 125 129 PF00917 0.644
DOC_USP7_MATH_1 209 213 PF00917 0.579
DOC_USP7_MATH_1 217 221 PF00917 0.596
DOC_USP7_MATH_1 28 32 PF00917 0.654
DOC_USP7_UBL2_3 144 148 PF12436 0.737
DOC_USP7_UBL2_3 158 162 PF12436 0.710
DOC_USP7_UBL2_3 249 253 PF12436 0.625
DOC_USP7_UBL2_3 53 57 PF12436 0.561
DOC_USP7_UBL2_3 83 87 PF12436 0.536
DOC_WW_Pin1_4 15 20 PF00397 0.621
DOC_WW_Pin1_4 162 167 PF00397 0.639
DOC_WW_Pin1_4 46 51 PF00397 0.625
LIG_14-3-3_CanoR_1 142 148 PF00244 0.657
LIG_14-3-3_CanoR_1 176 180 PF00244 0.570
LIG_14-3-3_CanoR_1 208 216 PF00244 0.615
LIG_BIR_III_2 25 29 PF00653 0.600
LIG_FHA_1 124 130 PF00498 0.709
LIG_FHA_1 175 181 PF00498 0.604
LIG_FHA_1 88 94 PF00498 0.593
LIG_FHA_2 266 272 PF00498 0.520
LIG_FHA_2 47 53 PF00498 0.615
LIG_LIR_Apic_2 31 36 PF02991 0.626
LIG_RPA_C_Fungi 74 86 PF08784 0.507
LIG_SH2_STAT5 21 24 PF00017 0.620
LIG_SH3_1 130 136 PF00018 0.694
LIG_SH3_3 130 136 PF00018 0.679
LIG_SH3_3 240 246 PF00018 0.733
LIG_SUMO_SIM_par_1 119 126 PF11976 0.544
LIG_SUMO_SIM_par_1 41 49 PF11976 0.642
LIG_TRAF2_1 49 52 PF00917 0.616
LIG_TRAF2_1 6 9 PF00917 0.651
LIG_TRAF2_1 65 68 PF00917 0.375
LIG_WW_3 137 141 PF00397 0.530
MOD_CDK_SPK_2 162 167 PF00069 0.522
MOD_CDK_SPxK_1 162 168 PF00069 0.524
MOD_CDK_SPxxK_3 46 53 PF00069 0.618
MOD_CK1_1 123 129 PF00069 0.546
MOD_CK1_1 13 19 PF00069 0.517
MOD_CK1_1 178 184 PF00069 0.721
MOD_CK1_1 248 254 PF00069 0.602
MOD_CK2_1 3 9 PF00069 0.542
MOD_CK2_1 38 44 PF00069 0.651
MOD_CK2_1 46 52 PF00069 0.530
MOD_Cter_Amidation 111 114 PF01082 0.582
MOD_Cter_Amidation 159 162 PF01082 0.667
MOD_Cter_Amidation 227 230 PF01082 0.544
MOD_Cter_Amidation 231 234 PF01082 0.665
MOD_GlcNHglycan 211 214 PF01048 0.582
MOD_GlcNHglycan 5 8 PF01048 0.609
MOD_GlcNHglycan 9 13 PF01048 0.563
MOD_GSK3_1 13 20 PF00069 0.651
MOD_GSK3_1 174 181 PF00069 0.735
MOD_GSK3_1 185 192 PF00069 0.622
MOD_NEK2_1 247 252 PF00069 0.655
MOD_NEK2_2 125 130 PF00069 0.643
MOD_PIKK_1 10 16 PF00454 0.521
MOD_PIKK_1 183 189 PF00454 0.564
MOD_PKA_1 183 189 PF00069 0.630
MOD_PKA_1 262 268 PF00069 0.503
MOD_PKA_2 175 181 PF00069 0.665
MOD_PKA_2 183 189 PF00069 0.734
MOD_PKA_2 262 268 PF00069 0.503
MOD_Plk_4 17 23 PF00069 0.620
MOD_Plk_4 175 181 PF00069 0.560
MOD_Plk_4 238 244 PF00069 0.670
MOD_ProDKin_1 15 21 PF00069 0.619
MOD_ProDKin_1 162 168 PF00069 0.641
MOD_ProDKin_1 46 52 PF00069 0.621
TRG_ER_diArg_1 139 142 PF00400 0.636
TRG_ER_diArg_1 166 168 PF00400 0.671
TRG_ER_diArg_1 182 184 PF00400 0.675
TRG_ER_diArg_1 207 209 PF00400 0.701
TRG_ER_diArg_1 29 32 PF00400 0.598
TRG_ER_diArg_1 97 99 PF00400 0.675
TRG_ER_diLys_1 272 276 PF00400 0.582
TRG_NLS_MonoExtC_3 157 162 PF00514 0.720
TRG_NLS_MonoExtC_3 82 87 PF00514 0.523
TRG_NLS_MonoExtN_4 155 162 PF00514 0.718
TRG_NLS_MonoExtN_4 83 88 PF00514 0.536
TRG_Pf-PMV_PEXEL_1 170 175 PF00026 0.662

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WW27 Leishmania donovani 80% 100%
A4HYU9 Leishmania infantum 80% 100%
E9AIF6 Leishmania braziliensis 51% 100%
Q4QCT9 Leishmania major 75% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS