Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AUP1_LEIMU

TriTrypDb:

LmxM.20.1030

Length:

218

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUP1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUP1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	162	166	PF00656	0.529
CLV_NRD_NRD_1	126	128	PF00675	0.665
CLV_NRD_NRD_1	182	184	PF00675	0.615
CLV_NRD_NRD_1	195	197	PF00675	0.577
CLV_PCSK_KEX2_1	101	103	PF00082	0.587
CLV_PCSK_KEX2_1	126	128	PF00082	0.550
CLV_PCSK_KEX2_1	181	183	PF00082	0.573
CLV_PCSK_PC1ET2_1	101	103	PF00082	0.506
CLV_PCSK_PC1ET2_1	126	128	PF00082	0.442
CLV_PCSK_PC1ET2_1	181	183	PF00082	0.573
CLV_PCSK_SKI1_1	142	146	PF00082	0.535
CLV_PCSK_SKI1_1	156	160	PF00082	0.527
CLV_PCSK_SKI1_1	168	172	PF00082	0.508
CLV_PCSK_SKI1_1	213	217	PF00082	0.468
CLV_PCSK_SKI1_1	94	98	PF00082	0.520
DOC_MAPK_gen_1	125	131	PF00069	0.504
DOC_MAPK_gen_1	97	108	PF00069	0.501
DOC_PP2B_LxvP_1	6	9	PF13499	0.559
DOC_PP4_FxxP_1	116	119	PF00568	0.520
DOC_PP4_MxPP_1	2	5	PF00568	0.534
DOC_USP7_MATH_1	119	123	PF00917	0.598
DOC_USP7_UBL2_3	121	125	PF12436	0.488
DOC_USP7_UBL2_3	181	185	PF12436	0.620
DOC_USP7_UBL2_3	94	98	PF12436	0.502
DOC_WW_Pin1_4	163	168	PF00397	0.535
LIG_14-3-3_CanoR_1	102	108	PF00244	0.547
LIG_EVH1_2	8	12	PF00568	0.503
LIG_FHA_1	203	209	PF00498	0.497
LIG_FHA_2	160	166	PF00498	0.528
LIG_FHA_2	81	87	PF00498	0.475
LIG_MYND_1	4	8	PF01753	0.604
LIG_SH2_STAP1	160	164	PF00017	0.595
LIG_SH3_3	1	7	PF00018	0.583
LIG_SH3_3	105	111	PF00018	0.511
LIG_SH3_3	161	167	PF00018	0.594
LIG_SH3_3	17	23	PF00018	0.645
LIG_SH3_3	27	33	PF00018	0.601
LIG_WW_2	30	33	PF00397	0.499
LIG_WW_2	4	7	PF00397	0.522
MOD_CDK_SPK_2	163	168	PF00069	0.535
MOD_CK1_1	14	20	PF00069	0.637
MOD_CK2_1	80	86	PF00069	0.512
MOD_Cter_Amidation	194	197	PF01082	0.588
MOD_Cter_Amidation	92	95	PF01082	0.505
MOD_GlcNHglycan	121	124	PF01048	0.602
MOD_GlcNHglycan	48	51	PF01048	0.694
MOD_GlcNHglycan	54	57	PF01048	0.574
MOD_GSK3_1	11	18	PF00069	0.512
MOD_GSK3_1	159	166	PF00069	0.536
MOD_GSK3_1	32	39	PF00069	0.612
MOD_GSK3_1	57	64	PF00069	0.569
MOD_GSK3_1	81	88	PF00069	0.581
MOD_N-GLC_1	36	41	PF02516	0.620
MOD_N-GLC_2	13	15	PF02516	0.518
MOD_NEK2_1	158	163	PF00069	0.565
MOD_NEK2_1	202	207	PF00069	0.600
MOD_NEK2_1	36	41	PF00069	0.602
MOD_PIKK_1	101	107	PF00454	0.633
MOD_PIKK_1	62	68	PF00454	0.654
MOD_PKA_1	101	107	PF00069	0.512
MOD_PKA_2	101	107	PF00069	0.591
MOD_PKA_2	195	201	PF00069	0.657
MOD_Plk_1	150	156	PF00069	0.555
MOD_Plk_1	36	42	PF00069	0.616
MOD_Plk_4	150	156	PF00069	0.530
MOD_Plk_4	159	165	PF00069	0.539
MOD_Plk_4	203	209	PF00069	0.578
MOD_ProDKin_1	163	169	PF00069	0.536
MOD_SUMO_for_1	109	112	PF00179	0.500
TRG_ER_diArg_1	182	184	PF00400	0.589
TRG_NLS_Bipartite_1	181	200	PF00514	0.656
TRG_NLS_MonoCore_2	124	129	PF00514	0.430
TRG_NLS_MonoExtC_3	180	185	PF00514	0.565
TRG_NLS_MonoExtC_3	93	98	PF00514	0.498
TRG_NLS_MonoExtN_4	125	130	PF00514	0.430
TRG_NLS_MonoExtN_4	179	185	PF00514	0.564
TRG_NLS_MonoExtN_4	194	200	PF00514	0.634
TRG_Pf-PMV_PEXEL_1	213	217	PF00026	0.399

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I456	Leptomonas seymouri	48%	68%
E9AIF3	Leishmania braziliensis	60%	100%
Q4QCU3	Leishmania major	83%	100%