Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AUL2_LEIMU

TriTrypDb:

LmxM.20.0690

Length:

1336

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1
GO:0000123	histone acetyltransferase complex	4	1
GO:0000124	SAGA complex	4	1
GO:0031248	protein acetyltransferase complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0070461	SAGA-type complex	5	1
GO:0140535	intracellular protein-containing complex	2	1
GO:1902493	acetyltransferase complex	4	1
GO:1902494	catalytic complex	2	1
GO:1905368	peptidase complex	3	1
GO:1990234	transferase complex	3	1

Expansion

Sequence features

E9AUL2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003712	transcription coregulator activity	2	1
GO:0140110	transcription regulator activity	1	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	486	490	PF00656	0.590
CLV_C14_Caspase3-7	559	563	PF00656	0.752
CLV_C14_Caspase3-7	567	571	PF00656	0.562
CLV_NRD_NRD_1	1106	1108	PF00675	0.627
CLV_NRD_NRD_1	126	128	PF00675	0.499
CLV_NRD_NRD_1	241	243	PF00675	0.597
CLV_NRD_NRD_1	301	303	PF00675	0.350
CLV_NRD_NRD_1	36	38	PF00675	0.451
CLV_NRD_NRD_1	44	46	PF00675	0.449
CLV_NRD_NRD_1	587	589	PF00675	0.594
CLV_NRD_NRD_1	590	592	PF00675	0.595
CLV_NRD_NRD_1	594	596	PF00675	0.608
CLV_NRD_NRD_1	609	611	PF00675	0.539
CLV_NRD_NRD_1	672	674	PF00675	0.561
CLV_NRD_NRD_1	679	681	PF00675	0.595
CLV_NRD_NRD_1	720	722	PF00675	0.635
CLV_PCSK_FUR_1	166	170	PF00082	0.494
CLV_PCSK_FUR_1	588	592	PF00082	0.595
CLV_PCSK_KEX2_1	1106	1108	PF00082	0.627
CLV_PCSK_KEX2_1	126	128	PF00082	0.479
CLV_PCSK_KEX2_1	168	170	PF00082	0.604
CLV_PCSK_KEX2_1	241	243	PF00082	0.657
CLV_PCSK_KEX2_1	301	303	PF00082	0.350
CLV_PCSK_KEX2_1	36	38	PF00082	0.451
CLV_PCSK_KEX2_1	44	46	PF00082	0.449
CLV_PCSK_KEX2_1	549	551	PF00082	0.594
CLV_PCSK_KEX2_1	587	589	PF00082	0.594
CLV_PCSK_KEX2_1	590	592	PF00082	0.595
CLV_PCSK_KEX2_1	593	595	PF00082	0.607
CLV_PCSK_KEX2_1	672	674	PF00082	0.561
CLV_PCSK_KEX2_1	679	681	PF00082	0.595
CLV_PCSK_KEX2_1	720	722	PF00082	0.635
CLV_PCSK_PC1ET2_1	126	128	PF00082	0.479
CLV_PCSK_PC1ET2_1	168	170	PF00082	0.604
CLV_PCSK_PC1ET2_1	549	551	PF00082	0.594
CLV_PCSK_PC1ET2_1	720	722	PF00082	0.581
CLV_PCSK_PC7_1	590	596	PF00082	0.602
CLV_PCSK_SKI1_1	44	48	PF00082	0.453
CLV_PCSK_SKI1_1	545	549	PF00082	0.570
CLV_PCSK_SKI1_1	573	577	PF00082	0.670
CLV_PCSK_SKI1_1	642	646	PF00082	0.419
CLV_PCSK_SKI1_1	852	856	PF00082	0.583
DEG_COP1_1	261	270	PF00400	0.573
DEG_COP1_1	578	585	PF00400	0.502
DEG_SPOP_SBC_1	1243	1247	PF00917	0.504
DOC_CYCLIN_yCln2_LP_2	364	370	PF00134	0.312
DOC_CYCLIN_yCln2_LP_2	854	860	PF00134	0.584
DOC_MAPK_DCC_7	360	370	PF00069	0.312
DOC_MAPK_gen_1	414	422	PF00069	0.355
DOC_PP2B_LxvP_1	196	199	PF13499	0.560
DOC_PP2B_LxvP_1	265	268	PF13499	0.579
DOC_PP2B_LxvP_1	854	857	PF13499	0.595
DOC_PP2B_LxvP_1	955	958	PF13499	0.502
DOC_PP4_FxxP_1	312	315	PF00568	0.414
DOC_PP4_FxxP_1	55	58	PF00568	0.438
DOC_PP4_MxPP_1	216	219	PF00568	0.555
DOC_USP7_MATH_1	1142	1146	PF00917	0.582
DOC_USP7_MATH_1	1234	1238	PF00917	0.616
DOC_USP7_MATH_1	201	205	PF00917	0.548
DOC_USP7_MATH_1	236	240	PF00917	0.548
DOC_USP7_MATH_1	560	564	PF00917	0.643
DOC_USP7_MATH_1	575	579	PF00917	0.530
DOC_USP7_MATH_1	583	587	PF00917	0.562
DOC_USP7_MATH_1	617	621	PF00917	0.525
DOC_USP7_MATH_1	747	751	PF00917	0.620
DOC_USP7_MATH_1	831	835	PF00917	0.421
DOC_USP7_MATH_1	84	88	PF00917	0.587
DOC_USP7_MATH_1	848	852	PF00917	0.426
DOC_USP7_MATH_1	884	888	PF00917	0.507
DOC_USP7_MATH_1	903	907	PF00917	0.545
DOC_USP7_MATH_1	958	962	PF00917	0.618
DOC_USP7_UBL2_3	164	168	PF12436	0.508
DOC_USP7_UBL2_3	174	178	PF12436	0.560
DOC_USP7_UBL2_3	545	549	PF12436	0.570
DOC_WW_Pin1_4	1160	1165	PF00397	0.628
DOC_WW_Pin1_4	178	183	PF00397	0.632
DOC_WW_Pin1_4	214	219	PF00397	0.610
DOC_WW_Pin1_4	249	254	PF00397	0.662
DOC_WW_Pin1_4	289	294	PF00397	0.515
DOC_WW_Pin1_4	389	394	PF00397	0.481
DOC_WW_Pin1_4	76	81	PF00397	0.472
DOC_WW_Pin1_4	783	788	PF00397	0.431
DOC_WW_Pin1_4	892	897	PF00397	0.622
DOC_WW_Pin1_4	921	926	PF00397	0.458
LIG_14-3-3_CanoR_1	1162	1168	PF00244	0.663
LIG_14-3-3_CanoR_1	207	216	PF00244	0.579
LIG_14-3-3_CanoR_1	610	617	PF00244	0.557
LIG_14-3-3_CanoR_1	852	857	PF00244	0.585
LIG_BIR_III_2	574	578	PF00653	0.627
LIG_BRCT_BRCA1_1	115	119	PF00533	0.504
LIG_BRCT_BRCA1_1	1322	1326	PF00533	0.533
LIG_BRCT_BRCA1_1	372	376	PF00533	0.314
LIG_eIF4E_1	359	365	PF01652	0.333
LIG_eIF4E_1	400	406	PF01652	0.404
LIG_FHA_1	148	154	PF00498	0.430
LIG_FHA_1	24	30	PF00498	0.484
LIG_FHA_1	462	468	PF00498	0.587
LIG_FHA_1	532	538	PF00498	0.436
LIG_FHA_1	59	65	PF00498	0.518
LIG_FHA_1	77	83	PF00498	0.394
LIG_FHA_2	1258	1264	PF00498	0.555
LIG_FHA_2	464	470	PF00498	0.495
LIG_FHA_2	484	490	PF00498	0.546
LIG_FHA_2	565	571	PF00498	0.675
LIG_FHA_2	613	619	PF00498	0.490
LIG_FHA_2	76	82	PF00498	0.477
LIG_IBAR_NPY_1	1278	1280	PF08397	0.661
LIG_IBAR_NPY_1	997	999	PF08397	0.436
LIG_Integrin_RGD_1	512	514	PF01839	0.633
LIG_LIR_Apic_2	310	315	PF02991	0.416
LIG_LIR_Gen_1	292	303	PF02991	0.418
LIG_LIR_Gen_1	348	359	PF02991	0.327
LIG_LIR_Gen_1	650	661	PF02991	0.439
LIG_LIR_Nem_3	1281	1285	PF02991	0.610
LIG_LIR_Nem_3	292	298	PF02991	0.458
LIG_LIR_Nem_3	348	354	PF02991	0.334
LIG_LIR_Nem_3	356	362	PF02991	0.319
LIG_LIR_Nem_3	650	656	PF02991	0.432
LIG_MAD2	852	860	PF02301	0.580
LIG_MLH1_MIPbox_1	1322	1326	PF16413	0.533
LIG_MYND_1	222	226	PF01753	0.593
LIG_PCNA_yPIPBox_3	421	433	PF02747	0.384
LIG_Pex14_2	351	355	PF04695	0.350
LIG_PTB_Apo_2	1325	1332	PF02174	0.454
LIG_PTB_Apo_2	394	401	PF02174	0.376
LIG_PTB_Phospho_1	394	400	PF10480	0.380
LIG_REV1ctd_RIR_1	1329	1336	PF16727	0.419
LIG_SH2_CRK	1181	1185	PF00017	0.636
LIG_SH2_CRK	359	363	PF00017	0.213
LIG_SH2_CRK	911	915	PF00017	0.479
LIG_SH2_CRK	995	999	PF00017	0.534
LIG_SH2_GRB2like	995	998	PF00017	0.475
LIG_SH2_NCK_1	1181	1185	PF00017	0.647
LIG_SH2_NCK_1	155	159	PF00017	0.531
LIG_SH2_NCK_1	911	915	PF00017	0.479
LIG_SH2_PTP2	361	364	PF00017	0.256
LIG_SH2_PTP2	844	847	PF00017	0.405
LIG_SH2_STAP1	155	159	PF00017	0.411
LIG_SH2_STAT3	1039	1042	PF00017	0.562
LIG_SH2_STAT5	308	311	PF00017	0.357
LIG_SH2_STAT5	361	364	PF00017	0.477
LIG_SH2_STAT5	380	383	PF00017	0.384
LIG_SH2_STAT5	54	57	PF00017	0.446
LIG_SH2_STAT5	838	841	PF00017	0.371
LIG_SH2_STAT5	844	847	PF00017	0.384
LIG_SH2_STAT5	868	871	PF00017	0.495
LIG_SH2_STAT5	927	930	PF00017	0.533
LIG_SH3_3	1174	1180	PF00018	0.636
LIG_SH3_3	1187	1193	PF00018	0.601
LIG_SH3_3	185	191	PF00018	0.479
LIG_SH3_3	215	221	PF00018	0.630
LIG_SH3_3	287	293	PF00018	0.590
LIG_SH3_3	387	393	PF00018	0.571
LIG_SH3_3	501	507	PF00018	0.547
LIG_SH3_3	749	755	PF00018	0.604
LIG_SH3_3	842	848	PF00018	0.412
LIG_SH3_3	854	860	PF00018	0.499
LIG_SH3_3	866	872	PF00018	0.495
LIG_SH3_3	893	899	PF00018	0.607
LIG_SUMO_SIM_par_1	462	469	PF11976	0.449
LIG_TRAF2_1	682	685	PF00917	0.601
LIG_TRAF2_1	715	718	PF00917	0.587
LIG_TYR_ITIM	842	847	PF00017	0.445
LIG_UBA3_1	639	645	PF00899	0.406
LIG_WW_2	1190	1193	PF00397	0.635
MOD_CDK_SPK_2	178	183	PF00069	0.588
MOD_CK1_1	1003	1009	PF00069	0.375
MOD_CK1_1	122	128	PF00069	0.553
MOD_CK1_1	1222	1228	PF00069	0.634
MOD_CK1_1	1242	1248	PF00069	0.477
MOD_CK1_1	146	152	PF00069	0.488
MOD_CK1_1	206	212	PF00069	0.726
MOD_CK1_1	280	286	PF00069	0.559
MOD_CK1_1	288	294	PF00069	0.456
MOD_CK1_1	310	316	PF00069	0.352
MOD_CK1_1	460	466	PF00069	0.459
MOD_CK1_1	531	537	PF00069	0.452
MOD_CK1_1	578	584	PF00069	0.602
MOD_CK1_1	586	592	PF00069	0.595
MOD_CK1_1	75	81	PF00069	0.537
MOD_CK1_1	83	89	PF00069	0.600
MOD_CK1_1	887	893	PF00069	0.525
MOD_CK1_1	961	967	PF00069	0.631
MOD_CK2_1	1222	1228	PF00069	0.704
MOD_CK2_1	288	294	PF00069	0.492
MOD_CK2_1	612	618	PF00069	0.536
MOD_CK2_1	622	628	PF00069	0.379
MOD_CK2_1	675	681	PF00069	0.571
MOD_Cter_Amidation	239	242	PF01082	0.566
MOD_GlcNHglycan	100	103	PF01048	0.581
MOD_GlcNHglycan	113	116	PF01048	0.495
MOD_GlcNHglycan	1158	1161	PF01048	0.656
MOD_GlcNHglycan	1172	1175	PF01048	0.620
MOD_GlcNHglycan	1186	1189	PF01048	0.548
MOD_GlcNHglycan	120	124	PF01048	0.516
MOD_GlcNHglycan	1224	1227	PF01048	0.668
MOD_GlcNHglycan	1231	1234	PF01048	0.583
MOD_GlcNHglycan	1236	1239	PF01048	0.560
MOD_GlcNHglycan	1241	1244	PF01048	0.520
MOD_GlcNHglycan	1246	1249	PF01048	0.562
MOD_GlcNHglycan	1253	1256	PF01048	0.462
MOD_GlcNHglycan	156	159	PF01048	0.561
MOD_GlcNHglycan	237	241	PF01048	0.554
MOD_GlcNHglycan	244	247	PF01048	0.640
MOD_GlcNHglycan	279	282	PF01048	0.566
MOD_GlcNHglycan	287	290	PF01048	0.464
MOD_GlcNHglycan	445	448	PF01048	0.381
MOD_GlcNHglycan	469	473	PF01048	0.633
MOD_GlcNHglycan	530	533	PF01048	0.596
MOD_GlcNHglycan	578	581	PF01048	0.606
MOD_GlcNHglycan	625	628	PF01048	0.477
MOD_GlcNHglycan	783	786	PF01048	0.518
MOD_GlcNHglycan	81	85	PF01048	0.547
MOD_GlcNHglycan	886	889	PF01048	0.623
MOD_GlcNHglycan	890	893	PF01048	0.654
MOD_GlcNHglycan	960	963	PF01048	0.628
MOD_GSK3_1	109	116	PF00069	0.691
MOD_GSK3_1	1156	1163	PF00069	0.630
MOD_GSK3_1	1218	1225	PF00069	0.649
MOD_GSK3_1	1234	1241	PF00069	0.624
MOD_GSK3_1	1274	1281	PF00069	0.605
MOD_GSK3_1	1320	1327	PF00069	0.605
MOD_GSK3_1	143	150	PF00069	0.370
MOD_GSK3_1	202	209	PF00069	0.593
MOD_GSK3_1	285	292	PF00069	0.487
MOD_GSK3_1	310	317	PF00069	0.460
MOD_GSK3_1	375	382	PF00069	0.328
MOD_GSK3_1	457	464	PF00069	0.652
MOD_GSK3_1	483	490	PF00069	0.595
MOD_GSK3_1	560	567	PF00069	0.792
MOD_GSK3_1	652	659	PF00069	0.435
MOD_GSK3_1	71	78	PF00069	0.472
MOD_GSK3_1	781	788	PF00069	0.501
MOD_GSK3_1	80	87	PF00069	0.497
MOD_GSK3_1	813	820	PF00069	0.578
MOD_GSK3_1	823	830	PF00069	0.503
MOD_GSK3_1	848	855	PF00069	0.475
MOD_GSK3_1	883	890	PF00069	0.607
MOD_GSK3_1	94	101	PF00069	0.431
MOD_GSK3_1	958	965	PF00069	0.496
MOD_N-GLC_1	109	114	PF02516	0.539
MOD_N-GLC_1	1222	1227	PF02516	0.668
MOD_N-GLC_1	1239	1244	PF02516	0.535
MOD_N-GLC_1	248	253	PF02516	0.684
MOD_N-GLC_1	258	263	PF02516	0.516
MOD_N-GLC_1	39	44	PF02516	0.432
MOD_N-GLC_1	565	570	PF02516	0.686
MOD_N-GLC_1	59	64	PF02516	0.372
MOD_N-GLC_1	675	680	PF02516	0.655
MOD_N-GLC_1	89	94	PF02516	0.410
MOD_N-GLC_2	340	342	PF02516	0.412
MOD_NEK2_1	109	114	PF00069	0.491
MOD_NEK2_1	1198	1203	PF00069	0.634
MOD_NEK2_1	13	18	PF00069	0.520
MOD_NEK2_1	147	152	PF00069	0.416
MOD_NEK2_1	154	159	PF00069	0.473
MOD_NEK2_1	176	181	PF00069	0.551
MOD_NEK2_1	277	282	PF00069	0.559
MOD_NEK2_1	370	375	PF00069	0.314
MOD_NEK2_1	381	386	PF00069	0.387
MOD_NEK2_1	39	44	PF00069	0.432
MOD_NEK2_1	443	448	PF00069	0.608
MOD_NEK2_1	461	466	PF00069	0.411
MOD_NEK2_1	493	498	PF00069	0.598
MOD_NEK2_1	675	680	PF00069	0.590
MOD_NEK2_1	697	702	PF00069	0.535
MOD_NEK2_1	781	786	PF00069	0.521
MOD_NEK2_1	91	96	PF00069	0.492
MOD_NEK2_2	307	312	PF00069	0.355
MOD_NEK2_2	617	622	PF00069	0.459
MOD_NEK2_2	652	657	PF00069	0.431
MOD_NEK2_2	84	89	PF00069	0.579
MOD_NMyristoyl	1	7	PF02799	0.468
MOD_OFUCOSY	305	311	PF10250	0.353
MOD_PIKK_1	1207	1213	PF00454	0.604
MOD_PIKK_1	1320	1326	PF00454	0.546
MOD_PIKK_1	209	215	PF00454	0.599
MOD_PIKK_1	375	381	PF00454	0.357
MOD_PIKK_1	737	743	PF00454	0.627
MOD_PIKK_1	858	864	PF00454	0.507
MOD_PIKK_1	937	943	PF00454	0.440
MOD_PIKK_1	962	968	PF00454	0.504
MOD_PK_1	169	175	PF00069	0.573
MOD_PK_1	314	320	PF00069	0.279
MOD_PKA_1	241	247	PF00069	0.678
MOD_PKA_2	206	212	PF00069	0.562
MOD_PKA_2	241	247	PF00069	0.676
MOD_PKA_2	564	570	PF00069	0.680
MOD_PKA_2	586	592	PF00069	0.663
MOD_PKA_2	609	615	PF00069	0.509
MOD_Plk_1	109	115	PF00069	0.565
MOD_Plk_1	143	149	PF00069	0.420
MOD_Plk_1	258	264	PF00069	0.607
MOD_Plk_1	461	467	PF00069	0.454
MOD_Plk_1	59	65	PF00069	0.518
MOD_Plk_1	617	623	PF00069	0.522
MOD_Plk_2-3	685	691	PF00069	0.650
MOD_Plk_4	1000	1006	PF00069	0.374
MOD_Plk_4	143	149	PF00069	0.420
MOD_Plk_4	370	376	PF00069	0.320
MOD_Plk_4	381	387	PF00069	0.444
MOD_Plk_4	489	495	PF00069	0.717
MOD_Plk_4	617	623	PF00069	0.458
MOD_Plk_4	656	662	PF00069	0.450
MOD_Plk_4	697	703	PF00069	0.531
MOD_Plk_4	790	796	PF00069	0.444
MOD_Plk_4	804	810	PF00069	0.555
MOD_Plk_4	831	837	PF00069	0.370
MOD_Plk_4	903	909	PF00069	0.561
MOD_Plk_4	94	100	PF00069	0.496
MOD_ProDKin_1	1160	1166	PF00069	0.628
MOD_ProDKin_1	178	184	PF00069	0.634
MOD_ProDKin_1	214	220	PF00069	0.606
MOD_ProDKin_1	249	255	PF00069	0.659
MOD_ProDKin_1	289	295	PF00069	0.510
MOD_ProDKin_1	389	395	PF00069	0.478
MOD_ProDKin_1	76	82	PF00069	0.473
MOD_ProDKin_1	783	789	PF00069	0.427
MOD_ProDKin_1	892	898	PF00069	0.616
MOD_ProDKin_1	921	927	PF00069	0.457
MOD_SUMO_rev_2	324	333	PF00179	0.551
MOD_SUMO_rev_2	352	362	PF00179	0.318
MOD_SUMO_rev_2	570	578	PF00179	0.696
TRG_DiLeu_BaEn_1	1067	1072	PF01217	0.512
TRG_DiLeu_BaEn_2	365	371	PF01217	0.312
TRG_DiLeu_BaEn_4	1067	1073	PF01217	0.514
TRG_DiLeu_BaLyEn_6	30	35	PF01217	0.539
TRG_DiLeu_LyEn_5	425	430	PF01217	0.400
TRG_ENDOCYTIC_2	1059	1062	PF00928	0.557
TRG_ENDOCYTIC_2	1181	1184	PF00928	0.635
TRG_ENDOCYTIC_2	133	136	PF00928	0.460
TRG_ENDOCYTIC_2	359	362	PF00928	0.361
TRG_ENDOCYTIC_2	400	403	PF00928	0.346
TRG_ENDOCYTIC_2	653	656	PF00928	0.495
TRG_ENDOCYTIC_2	844	847	PF00928	0.384
TRG_ENDOCYTIC_2	944	947	PF00928	0.538
TRG_ER_diArg_1	301	304	PF00400	0.348
TRG_ER_diArg_1	35	37	PF00400	0.453
TRG_ER_diArg_1	44	46	PF00400	0.449
TRG_ER_diArg_1	587	590	PF00400	0.593
TRG_ER_diArg_1	591	594	PF00400	0.602
TRG_NES_CRM1_1	419	431	PF08389	0.471
TRG_NLS_Bipartite_1	587	601	PF00514	0.597
TRG_NLS_MonoExtN_4	594	601	PF00514	0.598
TRG_NLS_MonoExtN_4	720	725	PF00514	0.596
TRG_Pf-PMV_PEXEL_1	1073	1077	PF00026	0.533
TRG_Pf-PMV_PEXEL_1	152	156	PF00026	0.375
TRG_Pf-PMV_PEXEL_1	421	425	PF00026	0.445
TRG_Pf-PMV_PEXEL_1	44	48	PF00026	0.518
TRG_Pf-PMV_PEXEL_1	673	677	PF00026	0.580

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZR7	Leptomonas seymouri	46%	100%
A0A3Q8IA11	Leishmania donovani	91%	100%
A4HYP3	Leishmania infantum	91%	100%
E9AIC5	Leishmania braziliensis	71%	95%
Q4QCX2	Leishmania major	87%	99%