Kinetoplast_ribosomal_PPR-repeat_-_putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplast ribosomal PPR-repeat containing protein 3, putative

Species:

Leishmania mexicana

UniProt:

E9AUJ2_LEIMU

TriTrypDb:

LmxM.20.0480

Length:

535

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0000315	organellar large ribosomal subunit	5	1
GO:0005762	mitochondrial large ribosomal subunit	3	1
GO:0015934	large ribosomal subunit	4	1
GO:0032991	protein-containing complex	1	1
GO:0044391	ribosomal subunit	3	1
GO:0098798	mitochondrial protein-containing complex	2	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

E9AUJ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUJ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	210	212	PF00675	0.462
CLV_NRD_NRD_1	25	27	PF00675	0.568
CLV_NRD_NRD_1	267	269	PF00675	0.444
CLV_NRD_NRD_1	295	297	PF00675	0.491
CLV_NRD_NRD_1	471	473	PF00675	0.331
CLV_NRD_NRD_1	483	485	PF00675	0.242
CLV_NRD_NRD_1	5	7	PF00675	0.595
CLV_PCSK_KEX2_1	24	26	PF00082	0.611
CLV_PCSK_KEX2_1	267	269	PF00082	0.510
CLV_PCSK_KEX2_1	295	297	PF00082	0.382
CLV_PCSK_KEX2_1	302	304	PF00082	0.389
CLV_PCSK_KEX2_1	471	473	PF00082	0.329
CLV_PCSK_KEX2_1	482	484	PF00082	0.248
CLV_PCSK_KEX2_1	7	9	PF00082	0.604
CLV_PCSK_PC1ET2_1	302	304	PF00082	0.416
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.452
CLV_PCSK_PC7_1	3	9	PF00082	0.572
CLV_PCSK_SKI1_1	106	110	PF00082	0.605
CLV_PCSK_SKI1_1	336	340	PF00082	0.338
CLV_PCSK_SKI1_1	343	347	PF00082	0.382
CLV_PCSK_SKI1_1	471	475	PF00082	0.310
CLV_PCSK_SKI1_1	497	501	PF00082	0.371
CLV_PCSK_SKI1_1	531	535	PF00082	0.559
DEG_Nend_UBRbox_3	1	3	PF02207	0.678
DEG_SPOP_SBC_1	325	329	PF00917	0.445
DOC_CKS1_1	282	287	PF01111	0.526
DOC_CKS1_1	417	422	PF01111	0.491
DOC_CKS1_1	63	68	PF01111	0.573
DOC_CYCLIN_RxL_1	332	342	PF00134	0.359
DOC_CYCLIN_RxL_1	494	502	PF00134	0.344
DOC_CYCLIN_yCln2_LP_2	380	386	PF00134	0.501
DOC_MAPK_DCC_7	303	313	PF00069	0.487
DOC_MAPK_gen_1	6	17	PF00069	0.442
DOC_MAPK_HePTP_8	516	528	PF00069	0.416
DOC_MAPK_MEF2A_6	519	528	PF00069	0.415
DOC_PP2B_LxvP_1	380	383	PF13499	0.518
DOC_PP4_FxxP_1	305	308	PF00568	0.451
DOC_SPAK_OSR1_1	98	102	PF12202	0.437
DOC_USP7_MATH_1	117	121	PF00917	0.342
DOC_USP7_MATH_1	130	134	PF00917	0.389
DOC_USP7_MATH_1	270	274	PF00917	0.352
DOC_USP7_MATH_1	33	37	PF00917	0.588
DOC_WW_Pin1_4	111	116	PF00397	0.457
DOC_WW_Pin1_4	219	224	PF00397	0.414
DOC_WW_Pin1_4	275	280	PF00397	0.648
DOC_WW_Pin1_4	281	286	PF00397	0.605
DOC_WW_Pin1_4	304	309	PF00397	0.355
DOC_WW_Pin1_4	416	421	PF00397	0.487
DOC_WW_Pin1_4	62	67	PF00397	0.649
LIG_14-3-3_CanoR_1	11	16	PF00244	0.612
LIG_14-3-3_CanoR_1	129	135	PF00244	0.416
LIG_14-3-3_CanoR_1	295	305	PF00244	0.380
LIG_14-3-3_CanoR_1	350	359	PF00244	0.316
LIG_14-3-3_CanoR_1	372	380	PF00244	0.466
LIG_14-3-3_CanoR_1	471	480	PF00244	0.309
LIG_14-3-3_CanoR_1	503	508	PF00244	0.420
LIG_14-3-3_CanoR_1	62	66	PF00244	0.624
LIG_14-3-3_CanoR_1	70	76	PF00244	0.690
LIG_FAT_LD_1	313	321	PF03623	0.325
LIG_FHA_1	12	18	PF00498	0.510
LIG_FHA_1	159	165	PF00498	0.603
LIG_FHA_1	276	282	PF00498	0.636
LIG_FHA_1	317	323	PF00498	0.374
LIG_FHA_1	372	378	PF00498	0.446
LIG_FHA_1	388	394	PF00498	0.190
LIG_FHA_1	417	423	PF00498	0.428
LIG_FHA_1	426	432	PF00498	0.348
LIG_FHA_1	454	460	PF00498	0.270
LIG_FHA_1	472	478	PF00498	0.270
LIG_FHA_1	489	495	PF00498	0.312
LIG_FHA_2	147	153	PF00498	0.671
LIG_FHA_2	282	288	PF00498	0.599
LIG_LIR_Gen_1	19	28	PF02991	0.533
LIG_LIR_Gen_1	342	348	PF02991	0.357
LIG_LIR_Gen_1	440	450	PF02991	0.307
LIG_LIR_Gen_1	455	463	PF02991	0.196
LIG_LIR_Nem_3	19	23	PF02991	0.548
LIG_LIR_Nem_3	264	269	PF02991	0.250
LIG_LIR_Nem_3	342	347	PF02991	0.366
LIG_LIR_Nem_3	351	356	PF02991	0.303
LIG_LIR_Nem_3	437	442	PF02991	0.286
LIG_LIR_Nem_3	455	460	PF02991	0.311
LIG_LIR_Nem_3	467	473	PF02991	0.256
LIG_NRBOX	215	221	PF00104	0.461
LIG_NRBOX	388	394	PF00104	0.412
LIG_NRBOX	425	431	PF00104	0.380
LIG_NRBOX	491	497	PF00104	0.270
LIG_PCNA_yPIPBox_3	486	500	PF02747	0.270
LIG_Pex3_1	496	507	PF04882	0.466
LIG_REV1ctd_RIR_1	263	272	PF16727	0.258
LIG_SH2_CRK	457	461	PF00017	0.312
LIG_SH2_NCK_1	260	264	PF00017	0.384
LIG_SH2_SRC	172	175	PF00017	0.397
LIG_SH2_SRC	75	78	PF00017	0.674
LIG_SH2_STAP1	242	246	PF00017	0.457
LIG_SH2_STAP1	353	357	PF00017	0.297
LIG_SH2_STAP1	373	377	PF00017	0.206
LIG_SH2_STAP1	457	461	PF00017	0.282
LIG_SH2_STAT3	298	301	PF00017	0.413
LIG_SH2_STAT5	134	137	PF00017	0.468
LIG_SH2_STAT5	172	175	PF00017	0.403
LIG_SH2_STAT5	298	301	PF00017	0.315
LIG_SH2_STAT5	353	356	PF00017	0.350
LIG_SH2_STAT5	373	376	PF00017	0.201
LIG_SH2_STAT5	401	404	PF00017	0.412
LIG_SH2_STAT5	457	460	PF00017	0.345
LIG_SH2_STAT5	75	78	PF00017	0.674
LIG_SH3_1	518	524	PF00018	0.514
LIG_SH3_3	193	199	PF00018	0.529
LIG_SH3_3	276	282	PF00018	0.593
LIG_SH3_3	342	348	PF00018	0.357
LIG_SH3_3	381	387	PF00018	0.502
LIG_SH3_3	414	420	PF00018	0.526
LIG_SH3_3	518	524	PF00018	0.514
LIG_SH3_3	63	69	PF00018	0.647
LIG_SUMO_SIM_anti_2	254	261	PF11976	0.390
LIG_SUMO_SIM_anti_2	318	324	PF11976	0.474
LIG_SUMO_SIM_anti_2	403	410	PF11976	0.285
LIG_SUMO_SIM_anti_2	458	463	PF11976	0.285
LIG_SUMO_SIM_par_1	309	314	PF11976	0.340
LIG_SUMO_SIM_par_1	318	324	PF11976	0.360
LIG_SUMO_SIM_par_1	427	433	PF11976	0.339
LIG_TRAF2_1	124	127	PF00917	0.531
LIG_TRFH_1	344	348	PF08558	0.428
LIG_TYR_ITIM	511	516	PF00017	0.233
LIG_UBA3_1	388	394	PF00899	0.412
LIG_UBA3_1	459	466	PF00899	0.404
LIG_WRC_WIRS_1	17	22	PF05994	0.446
LIG_WRC_WIRS_1	504	509	PF05994	0.414
MOD_CDK_SPK_2	65	70	PF00069	0.681
MOD_CK1_1	261	267	PF00069	0.445
MOD_CK1_1	321	327	PF00069	0.426
MOD_CK1_1	36	42	PF00069	0.662
MOD_CK1_1	407	413	PF00069	0.467
MOD_CK1_1	425	431	PF00069	0.289
MOD_CK1_1	437	443	PF00069	0.362
MOD_CK2_1	117	123	PF00069	0.308
MOD_CK2_1	172	178	PF00069	0.406
MOD_GlcNHglycan	273	276	PF01048	0.614
MOD_GlcNHglycan	39	42	PF01048	0.622
MOD_GlcNHglycan	398	401	PF01048	0.383
MOD_GSK3_1	168	175	PF00069	0.457
MOD_GSK3_1	271	278	PF00069	0.553
MOD_GSK3_1	32	39	PF00069	0.582
MOD_GSK3_1	321	328	PF00069	0.379
MOD_GSK3_1	351	358	PF00069	0.384
MOD_GSK3_1	425	432	PF00069	0.409
MOD_GSK3_1	61	68	PF00069	0.623
MOD_LATS_1	501	507	PF00433	0.263
MOD_N-GLC_1	396	401	PF02516	0.412
MOD_N-GLC_1	422	427	PF02516	0.332
MOD_NEK2_1	168	173	PF00069	0.495
MOD_NEK2_1	236	241	PF00069	0.254
MOD_NEK2_1	258	263	PF00069	0.386
MOD_NEK2_1	31	36	PF00069	0.599
MOD_NEK2_1	316	321	PF00069	0.343
MOD_NEK2_1	396	401	PF00069	0.412
MOD_NEK2_1	445	450	PF00069	0.326
MOD_PIKK_1	464	470	PF00454	0.347
MOD_PIKK_1	75	81	PF00454	0.649
MOD_PIKK_1	83	89	PF00454	0.592
MOD_PK_1	446	452	PF00069	0.308
MOD_PKA_1	471	477	PF00069	0.399
MOD_PKA_2	10	16	PF00069	0.545
MOD_PKA_2	128	134	PF00069	0.413
MOD_PKA_2	271	277	PF00069	0.550
MOD_PKA_2	349	355	PF00069	0.316
MOD_PKA_2	371	377	PF00069	0.452
MOD_PKA_2	445	451	PF00069	0.399
MOD_PKA_2	471	477	PF00069	0.329
MOD_PKA_2	61	67	PF00069	0.553
MOD_PKA_2	69	75	PF00069	0.593
MOD_PKB_1	24	32	PF00069	0.723
MOD_Plk_1	422	428	PF00069	0.330
MOD_Plk_1	446	452	PF00069	0.264
MOD_Plk_1	488	494	PF00069	0.475
MOD_Plk_4	130	136	PF00069	0.416
MOD_Plk_4	168	174	PF00069	0.542
MOD_Plk_4	252	258	PF00069	0.514
MOD_Plk_4	261	267	PF00069	0.437
MOD_Plk_4	318	324	PF00069	0.407
MOD_Plk_4	404	410	PF00069	0.308
MOD_Plk_4	425	431	PF00069	0.414
MOD_Plk_4	455	461	PF00069	0.304
MOD_ProDKin_1	111	117	PF00069	0.450
MOD_ProDKin_1	219	225	PF00069	0.417
MOD_ProDKin_1	275	281	PF00069	0.641
MOD_ProDKin_1	304	310	PF00069	0.355
MOD_ProDKin_1	416	422	PF00069	0.481
MOD_ProDKin_1	62	68	PF00069	0.649
MOD_SUMO_for_1	228	231	PF00179	0.534
TRG_DiLeu_BaEn_1	254	259	PF01217	0.462
TRG_DiLeu_BaEn_1	404	409	PF01217	0.286
TRG_DiLeu_BaEn_1	455	460	PF01217	0.304
TRG_DiLeu_BaEn_3	231	237	PF01217	0.321
TRG_DiLeu_BaLyEn_6	333	338	PF01217	0.328
TRG_DiLeu_BaLyEn_6	417	422	PF01217	0.491
TRG_DiLeu_BaLyEn_6	529	534	PF01217	0.547
TRG_ENDOCYTIC_2	356	359	PF00928	0.384
TRG_ENDOCYTIC_2	442	445	PF00928	0.326
TRG_ENDOCYTIC_2	457	460	PF00928	0.183
TRG_ENDOCYTIC_2	512	515	PF00928	0.334
TRG_ER_diArg_1	23	26	PF00400	0.717
TRG_ER_diArg_1	266	268	PF00400	0.437
TRG_ER_diArg_1	294	296	PF00400	0.496
TRG_ER_diArg_1	470	472	PF00400	0.334
TRG_ER_diArg_1	482	484	PF00400	0.243
TRG_ER_diArg_1	5	8	PF00400	0.505
TRG_NLS_MonoExtN_4	3	10	PF00514	0.454
TRG_Pf-PMV_PEXEL_1	106	110	PF00026	0.419
TRG_Pf-PMV_PEXEL_1	193	197	PF00026	0.404
TRG_Pf-PMV_PEXEL_1	214	218	PF00026	0.380
TRG_Pf-PMV_PEXEL_1	336	340	PF00026	0.323
TRG_Pf-PMV_PEXEL_1	394	398	PF00026	0.364
TRG_Pf-PMV_PEXEL_1	531	535	PF00026	0.413

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7Z9	Leptomonas seymouri	68%	97%
A0A0S4J3K2	Bodo saltans	38%	74%
A0A1X0NWF6	Trypanosomatidae	52%	100%
A0A3Q8IBN5	Leishmania donovani	90%	97%
A0A3R7K7U1	Trypanosoma rangeli	50%	100%
A4HYR3	Leishmania infantum	91%	100%
C9ZI67	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
Q4QCZ2	Leishmania major	89%	100%
V5BQU6	Trypanosoma cruzi	55%	100%