LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AUH6_LEIMU
TriTrypDb:
LmxM.20.0343
Length:
124

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUH6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUH6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 119 121 PF00675 0.739
CLV_PCSK_KEX2_1 119 121 PF00082 0.739
CLV_PCSK_PC7_1 115 121 PF00082 0.523
DOC_CYCLIN_yCln2_LP_2 34 40 PF00134 0.505
DOC_PP2B_LxvP_1 34 37 PF13499 0.524
DOC_WW_Pin1_4 114 119 PF00397 0.766
LIG_BIR_II_1 1 5 PF00653 0.499
LIG_BIR_III_2 10 14 PF00653 0.502
LIG_BIR_III_3 1 5 PF00653 0.499
LIG_deltaCOP1_diTrp_1 92 100 PF00928 0.511
LIG_LIR_Nem_3 101 107 PF02991 0.476
LIG_MYND_1 13 17 PF01753 0.508
LIG_SH2_SRC 6 9 PF00017 0.485
LIG_SH2_STAT5 6 9 PF00017 0.485
LIG_SH3_3 11 17 PF00018 0.537
LIG_SH3_3 2 8 PF00018 0.487
LIG_SH3_3 53 59 PF00018 0.677
LIG_SH3_3 82 88 PF00018 0.546
MOD_CDC14_SPxK_1 117 120 PF00782 0.600
MOD_CDK_SPK_2 114 119 PF00069 0.600
MOD_CDK_SPxK_1 114 120 PF00069 0.600
MOD_CK1_1 30 36 PF00069 0.548
MOD_GSK3_1 15 22 PF00069 0.604
MOD_GSK3_1 63 70 PF00069 0.596
MOD_NEK2_1 72 77 PF00069 0.538
MOD_PKA_2 45 51 PF00069 0.590
MOD_PKA_2 63 69 PF00069 0.519
MOD_PKA_2 73 79 PF00069 0.624
MOD_Plk_1 30 36 PF00069 0.529
MOD_ProDKin_1 114 120 PF00069 0.766
TRG_ER_diArg_1 118 120 PF00400 0.745
TRG_ER_diArg_1 50 53 PF00400 0.505

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WVU3 Leishmania donovani 71% 98%
A4HYS1 Leishmania infantum 71% 98%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS