Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AUH4_LEIMU

TriTrypDb:

LmxM.20.0330

Length:

313

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUH4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUH4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	284	288	PF00656	0.471
CLV_C14_Caspase3-7	53	57	PF00656	0.550
CLV_NRD_NRD_1	128	130	PF00675	0.545
CLV_NRD_NRD_1	280	282	PF00675	0.596
CLV_NRD_NRD_1	30	32	PF00675	0.456
CLV_NRD_NRD_1	310	312	PF00675	0.597
CLV_PCSK_KEX2_1	128	130	PF00082	0.545
CLV_PCSK_KEX2_1	280	282	PF00082	0.596
CLV_PCSK_KEX2_1	30	32	PF00082	0.456
CLV_PCSK_KEX2_1	310	312	PF00082	0.597
CLV_PCSK_SKI1_1	211	215	PF00082	0.447
CLV_PCSK_SKI1_1	286	290	PF00082	0.592
CLV_PCSK_SKI1_1	30	34	PF00082	0.518
CLV_PCSK_SKI1_1	67	71	PF00082	0.695
CLV_PCSK_SKI1_1	98	102	PF00082	0.502
DEG_COP1_1	116	127	PF00400	0.510
DEG_Nend_Nbox_1	1	3	PF02207	0.525
DOC_CYCLIN_RxL_1	26	38	PF00134	0.518
DOC_MAPK_gen_1	208	218	PF00069	0.444
DOC_MAPK_gen_1	27	35	PF00069	0.438
DOC_MAPK_MEF2A_6	211	218	PF00069	0.470
DOC_MAPK_NFAT4_5	211	219	PF00069	0.352
DOC_PP2B_LxvP_1	214	217	PF13499	0.547
DOC_USP7_MATH_1	177	181	PF00917	0.538
DOC_USP7_MATH_1	271	275	PF00917	0.543
DOC_USP7_MATH_1	298	302	PF00917	0.524
DOC_WW_Pin1_4	294	299	PF00397	0.511
DOC_WW_Pin1_4	305	310	PF00397	0.547
DOC_WW_Pin1_4	76	81	PF00397	0.732
LIG_14-3-3_CanoR_1	113	122	PF00244	0.520
LIG_14-3-3_CanoR_1	146	151	PF00244	0.556
LIG_14-3-3_CanoR_1	208	218	PF00244	0.356
LIG_14-3-3_CanoR_1	98	104	PF00244	0.529
LIG_FHA_1	225	231	PF00498	0.540
LIG_FHA_1	95	101	PF00498	0.580
LIG_FHA_2	100	106	PF00498	0.686
LIG_FHA_2	114	120	PF00498	0.653
LIG_FHA_2	190	196	PF00498	0.489
LIG_FHA_2	282	288	PF00498	0.454
LIG_FHA_2	51	57	PF00498	0.503
LIG_LIR_Gen_1	143	150	PF02991	0.551
LIG_LIR_Nem_3	143	147	PF02991	0.554
LIG_Pex14_2	110	114	PF04695	0.685
LIG_SH2_CRK	258	262	PF00017	0.640
LIG_SH2_STAT3	63	66	PF00017	0.507
LIG_SH2_STAT5	202	205	PF00017	0.400
LIG_SH2_STAT5	43	46	PF00017	0.613
LIG_SH3_1	128	134	PF00018	0.704
LIG_SH3_1	75	81	PF00018	0.705
LIG_SH3_3	119	125	PF00018	0.583
LIG_SH3_3	128	134	PF00018	0.634
LIG_SH3_3	185	191	PF00018	0.544
LIG_SH3_3	75	81	PF00018	0.717
LIG_SUMO_SIM_par_1	31	38	PF11976	0.453
LIG_TRAF2_1	10	13	PF00917	0.464
LIG_WW_3	130	134	PF00397	0.648
MOD_CDC14_SPxK_1	308	311	PF00782	0.525
MOD_CDK_SPK_2	305	310	PF00069	0.566
MOD_CDK_SPxK_1	305	311	PF00069	0.516
MOD_CK1_1	297	303	PF00069	0.690
MOD_CK1_1	38	44	PF00069	0.460
MOD_CK2_1	189	195	PF00069	0.495
MOD_CK2_1	34	40	PF00069	0.527
MOD_CK2_1	99	105	PF00069	0.779
MOD_GlcNHglycan	162	165	PF01048	0.686
MOD_GlcNHglycan	168	171	PF01048	0.786
MOD_GlcNHglycan	174	177	PF01048	0.518
MOD_GSK3_1	160	167	PF00069	0.708
MOD_GSK3_1	177	184	PF00069	0.585
MOD_GSK3_1	231	238	PF00069	0.399
MOD_GSK3_1	294	301	PF00069	0.536
MOD_GSK3_1	34	41	PF00069	0.496
MOD_GSK3_1	94	101	PF00069	0.777
MOD_N-GLC_1	164	169	PF02516	0.703
MOD_NEK2_1	160	165	PF00069	0.585
MOD_NEK2_1	183	188	PF00069	0.599
MOD_NEK2_1	233	238	PF00069	0.533
MOD_PIKK_1	231	237	PF00454	0.392
MOD_PKA_2	145	151	PF00069	0.580
MOD_PKB_1	96	104	PF00069	0.523
MOD_Plk_1	286	292	PF00069	0.496
MOD_Plk_1	298	304	PF00069	0.486
MOD_Plk_1	35	41	PF00069	0.448
MOD_Plk_2-3	189	195	PF00069	0.496
MOD_Plk_4	189	195	PF00069	0.496
MOD_Plk_4	38	44	PF00069	0.492
MOD_ProDKin_1	294	300	PF00069	0.515
MOD_ProDKin_1	305	311	PF00069	0.551
MOD_ProDKin_1	76	82	PF00069	0.734
TRG_DiLeu_BaLyEn_6	225	230	PF01217	0.464
TRG_ENDOCYTIC_2	258	261	PF00928	0.634
TRG_ER_diArg_1	127	129	PF00400	0.618
TRG_ER_diArg_1	225	228	PF00400	0.441
TRG_ER_diArg_1	30	32	PF00400	0.462
TRG_ER_diArg_1	309	311	PF00400	0.593
TRG_ER_diArg_1	95	98	PF00400	0.514
TRG_Pf-PMV_PEXEL_1	31	36	PF00026	0.515

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P529	Leptomonas seymouri	43%	97%
A0A3S7WVT8	Leishmania donovani	85%	99%
A4HYR9	Leishmania infantum	85%	99%
E9AI89	Leishmania braziliensis	65%	100%
Q4QD10	Leishmania major	80%	100%