DUF1508 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AUF9_LEIMU

TriTrypDb:

LmxM.20.0190

Length:

198

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUF9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	176	180	PF00656	0.565
CLV_NRD_NRD_1	136	138	PF00675	0.570
CLV_NRD_NRD_1	166	168	PF00675	0.545
CLV_NRD_NRD_1	2	4	PF00675	0.638
CLV_PCSK_KEX2_1	136	138	PF00082	0.605
CLV_PCSK_KEX2_1	166	168	PF00082	0.535
CLV_PCSK_KEX2_1	2	4	PF00082	0.632
DEG_Nend_UBRbox_1	1	4	PF02207	0.572
DEG_SCF_FBW7_1	27	33	PF00400	0.353
DEG_SPOP_SBC_1	44	48	PF00917	0.611
DOC_CKS1_1	27	32	PF01111	0.349
DOC_CYCLIN_yCln2_LP_2	38	44	PF00134	0.372
DOC_CYCLIN_yCln2_LP_2	50	56	PF00134	0.472
DOC_PP2B_LxvP_1	38	41	PF13499	0.423
DOC_SPAK_OSR1_1	80	84	PF12202	0.376
DOC_USP7_MATH_1	119	123	PF00917	0.598
DOC_USP7_MATH_1	17	21	PF00917	0.488
DOC_USP7_MATH_1	30	34	PF00917	0.654
DOC_USP7_MATH_1	45	49	PF00917	0.671
DOC_WW_Pin1_4	26	31	PF00397	0.364
DOC_WW_Pin1_4	49	54	PF00397	0.688
LIG_14-3-3_CanoR_1	39	45	PF00244	0.556
LIG_14-3-3_CanoR_1	61	66	PF00244	0.606
LIG_14-3-3_CterR_2	194	198	PF00244	0.588
LIG_BIR_III_4	113	117	PF00653	0.477
LIG_BIR_III_4	76	80	PF00653	0.409
LIG_BRCT_BRCA1_1	149	153	PF00533	0.485
LIG_deltaCOP1_diTrp_1	164	168	PF00928	0.430
LIG_FHA_1	173	179	PF00498	0.320
LIG_FHA_1	33	39	PF00498	0.482
LIG_FHA_1	8	14	PF00498	0.472
LIG_FHA_1	86	92	PF00498	0.538
LIG_FHA_2	122	128	PF00498	0.648
LIG_LIR_Gen_1	147	155	PF02991	0.520
LIG_LIR_Nem_3	147	152	PF02991	0.518
LIG_LIR_Nem_3	163	168	PF02991	0.402
LIG_Pex14_2	145	149	PF04695	0.387
LIG_SH2_STAP1	142	146	PF00017	0.460
LIG_SH2_STAT5	8	11	PF00017	0.541
LIG_SH3_3	24	30	PF00018	0.330
LIG_SH3_3	50	56	PF00018	0.558
MOD_CK1_1	147	153	PF00069	0.453
MOD_CK1_1	169	175	PF00069	0.573
MOD_CK1_1	52	58	PF00069	0.659
MOD_CK1_1	7	13	PF00069	0.568
MOD_CK2_1	121	127	PF00069	0.648
MOD_GlcNHglycan	129	132	PF01048	0.692
MOD_GlcNHglycan	168	171	PF01048	0.574
MOD_GlcNHglycan	187	190	PF01048	0.330
MOD_GlcNHglycan	85	88	PF01048	0.544
MOD_GSK3_1	140	147	PF00069	0.498
MOD_GSK3_1	181	188	PF00069	0.422
MOD_GSK3_1	26	33	PF00069	0.657
MOD_GSK3_1	40	47	PF00069	0.652
MOD_GSK3_1	57	64	PF00069	0.571
MOD_GSK3_1	9	16	PF00069	0.556
MOD_N-GLC_1	13	18	PF02516	0.446
MOD_NEK2_1	144	149	PF00069	0.386
MOD_NEK2_1	181	186	PF00069	0.318
MOD_PKA_1	166	172	PF00069	0.492
MOD_PKA_1	4	10	PF00069	0.529
MOD_PKA_2	166	172	PF00069	0.492
MOD_Plk_4	140	146	PF00069	0.418
MOD_Plk_4	181	187	PF00069	0.319
MOD_Plk_4	32	38	PF00069	0.544
MOD_Plk_4	4	10	PF00069	0.523
MOD_Plk_4	45	51	PF00069	0.688
MOD_ProDKin_1	26	32	PF00069	0.365
MOD_ProDKin_1	49	55	PF00069	0.687
MOD_SUMO_rev_2	169	175	PF00179	0.414
MOD_SUMO_rev_2	20	30	PF00179	0.486
TRG_ENDOCYTIC_2	142	145	PF00928	0.408
TRG_ER_diArg_1	1	3	PF00400	0.645
TRG_ER_diArg_1	135	137	PF00400	0.677
TRG_ER_diArg_1	165	167	PF00400	0.520
TRG_ER_diArg_1	78	81	PF00400	0.478
TRG_NLS_MonoExtN_4	2	7	PF00514	0.574

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWU9	Leptomonas seymouri	32%	100%
A0A1X0NWM2	Trypanosomatidae	26%	100%
A0A3Q8IBI0	Leishmania donovani	82%	99%
A0A422NEH1	Trypanosoma rangeli	29%	100%
A4HYL0	Leishmania infantum	85%	100%
Q4QD25	Leishmania major	79%	100%