ANK_REP_REGION domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved,calphotin-like protein

Species:

Leishmania mexicana

UniProt:

E9AUC2_LEIMU

TriTrypDb:

LmxM.36.6860

Length:

429

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AUC2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AUC2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	245	249	PF00656	0.758
CLV_NRD_NRD_1	16	18	PF00675	0.665
CLV_NRD_NRD_1	221	223	PF00675	0.628
CLV_NRD_NRD_1	250	252	PF00675	0.681
CLV_NRD_NRD_1	282	284	PF00675	0.643
CLV_NRD_NRD_1	299	301	PF00675	0.451
CLV_PCSK_KEX2_1	188	190	PF00082	0.762
CLV_PCSK_KEX2_1	221	223	PF00082	0.628
CLV_PCSK_KEX2_1	282	284	PF00082	0.646
CLV_PCSK_KEX2_1	298	300	PF00082	0.480
CLV_PCSK_KEX2_1	305	307	PF00082	0.617
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.762
CLV_PCSK_PC1ET2_1	282	284	PF00082	0.631
CLV_PCSK_PC1ET2_1	305	307	PF00082	0.641
CLV_PCSK_SKI1_1	17	21	PF00082	0.691
CLV_PCSK_SKI1_1	221	225	PF00082	0.780
CLV_PCSK_SKI1_1	351	355	PF00082	0.621
DEG_APCC_DBOX_1	410	418	PF00400	0.726
DEG_SPOP_SBC_1	182	186	PF00917	0.499
DOC_CKS1_1	4	9	PF01111	0.539
DOC_MAPK_MEF2A_6	330	338	PF00069	0.590
DOC_PP1_RVXF_1	15	22	PF00149	0.656
DOC_PP1_RVXF_1	199	205	PF00149	0.595
DOC_PP2B_LxvP_1	56	59	PF13499	0.819
DOC_PP4_FxxP_1	270	273	PF00568	0.611
DOC_USP7_MATH_1	229	233	PF00917	0.597
DOC_USP7_MATH_1	393	397	PF00917	0.554
DOC_WW_Pin1_4	117	122	PF00397	0.774
DOC_WW_Pin1_4	129	134	PF00397	0.573
DOC_WW_Pin1_4	269	274	PF00397	0.617
DOC_WW_Pin1_4	3	8	PF00397	0.739
DOC_WW_Pin1_4	31	36	PF00397	0.764
DOC_WW_Pin1_4	317	322	PF00397	0.525
DOC_WW_Pin1_4	409	414	PF00397	0.750
DOC_WW_Pin1_4	61	66	PF00397	0.743
DOC_WW_Pin1_4	87	92	PF00397	0.658
DOC_WW_Pin1_4	9	14	PF00397	0.806
LIG_14-3-3_CanoR_1	143	150	PF00244	0.718
LIG_14-3-3_CanoR_1	17	22	PF00244	0.666
LIG_14-3-3_CanoR_1	228	234	PF00244	0.825
LIG_14-3-3_CanoR_1	73	80	PF00244	0.748
LIG_BIR_II_1	1	5	PF00653	0.820
LIG_EVH1_2	121	125	PF00568	0.790
LIG_FHA_1	130	136	PF00498	0.601
LIG_FHA_1	18	24	PF00498	0.816
LIG_FHA_1	188	194	PF00498	0.663
LIG_FHA_1	241	247	PF00498	0.728
LIG_FHA_1	308	314	PF00498	0.560
LIG_FHA_1	392	398	PF00498	0.604
LIG_FHA_2	243	249	PF00498	0.755
LIG_FHA_2	73	79	PF00498	0.827
LIG_LIR_Gen_1	160	169	PF02991	0.687
LIG_LIR_Nem_3	160	164	PF02991	0.594
LIG_LIR_Nem_3	291	297	PF02991	0.617
LIG_LIR_Nem_3	344	350	PF02991	0.559
LIG_LYPXL_S_1	108	112	PF13949	0.757
LIG_LYPXL_yS_3	109	112	PF13949	0.761
LIG_MYND_1	39	43	PF01753	0.680
LIG_PCNA_PIPBox_1	208	217	PF02747	0.650
LIG_Pex14_1	265	269	PF04695	0.581
LIG_PTAP_UEV_1	58	63	PF05743	0.538
LIG_SH2_STAT5	161	164	PF00017	0.590
LIG_SH2_STAT5	215	218	PF00017	0.693
LIG_SH2_STAT5	269	272	PF00017	0.603
LIG_SH2_STAT5	294	297	PF00017	0.614
LIG_SH3_2	13	18	PF14604	0.532
LIG_SH3_3	1	7	PF00018	0.760
LIG_SH3_3	10	16	PF00018	0.773
LIG_SH3_3	174	180	PF00018	0.726
LIG_SH3_3	30	36	PF00018	0.642
LIG_SH3_3	362	368	PF00018	0.623
LIG_SH3_3	40	46	PF00018	0.656
LIG_SH3_3	56	62	PF00018	0.545
LIG_SH3_3	64	70	PF00018	0.657
LIG_SUMO_SIM_anti_2	173	178	PF11976	0.556
LIG_SUMO_SIM_anti_2	332	340	PF11976	0.452
LIG_SUMO_SIM_par_1	179	186	PF11976	0.780
LIG_SUMO_SIM_par_1	332	340	PF11976	0.452
LIG_TRAF2_1	74	77	PF00917	0.832
LIG_Vh1_VBS_1	324	342	PF01044	0.523
LIG_WW_1	158	161	PF00397	0.730
MOD_CDC14_SPxK_1	90	93	PF00782	0.561
MOD_CDK_SPxK_1	87	93	PF00069	0.621
MOD_CK1_1	117	123	PF00069	0.672
MOD_CK1_1	170	176	PF00069	0.601
MOD_CK1_1	231	237	PF00069	0.810
MOD_CK1_1	24	30	PF00069	0.574
MOD_CK1_1	3	9	PF00069	0.636
MOD_CK1_1	317	323	PF00069	0.521
MOD_CK1_1	355	361	PF00069	0.634
MOD_CK1_1	396	402	PF00069	0.625
MOD_CK2_1	142	148	PF00069	0.577
MOD_CK2_1	72	78	PF00069	0.838
MOD_GlcNHglycan	116	119	PF01048	0.625
MOD_GlcNHglycan	137	140	PF01048	0.604
MOD_GlcNHglycan	169	172	PF01048	0.658
MOD_GlcNHglycan	185	188	PF01048	0.491
MOD_GlcNHglycan	23	26	PF01048	0.743
MOD_GlcNHglycan	290	293	PF01048	0.551
MOD_GlcNHglycan	339	342	PF01048	0.553
MOD_GlcNHglycan	354	357	PF01048	0.391
MOD_GlcNHglycan	59	62	PF01048	0.579
MOD_GSK3_1	113	120	PF00069	0.765
MOD_GSK3_1	17	24	PF00069	0.787
MOD_GSK3_1	183	190	PF00069	0.567
MOD_GSK3_1	227	234	PF00069	0.816
MOD_GSK3_1	240	247	PF00069	0.595
MOD_GSK3_1	393	400	PF00069	0.713
MOD_GSK3_1	57	64	PF00069	0.584
MOD_NEK2_1	113	118	PF00069	0.761
MOD_NEK2_1	181	186	PF00069	0.701
MOD_NEK2_1	21	26	PF00069	0.743
MOD_NEK2_1	288	293	PF00069	0.562
MOD_NEK2_1	337	342	PF00069	0.485
MOD_NEK2_2	393	398	PF00069	0.498
MOD_PK_1	330	336	PF00069	0.468
MOD_PKA_1	17	23	PF00069	0.817
MOD_PKA_1	221	227	PF00069	0.639
MOD_PKA_2	142	148	PF00069	0.724
MOD_PKA_2	167	173	PF00069	0.565
MOD_PKA_2	221	227	PF00069	0.743
MOD_PKA_2	342	348	PF00069	0.531
MOD_PKA_2	72	78	PF00069	0.763
MOD_Plk_4	330	336	PF00069	0.536
MOD_Plk_4	361	367	PF00069	0.577
MOD_Plk_4	393	399	PF00069	0.539
MOD_ProDKin_1	117	123	PF00069	0.777
MOD_ProDKin_1	129	135	PF00069	0.573
MOD_ProDKin_1	269	275	PF00069	0.618
MOD_ProDKin_1	3	9	PF00069	0.738
MOD_ProDKin_1	31	37	PF00069	0.765
MOD_ProDKin_1	317	323	PF00069	0.521
MOD_ProDKin_1	409	415	PF00069	0.751
MOD_ProDKin_1	61	67	PF00069	0.741
MOD_ProDKin_1	87	93	PF00069	0.657
MOD_SUMO_for_1	216	219	PF00179	0.658
TRG_DiLeu_BaLyEn_6	67	72	PF01217	0.763
TRG_ENDOCYTIC_2	109	112	PF00928	0.636
TRG_ENDOCYTIC_2	161	164	PF00928	0.623
TRG_ENDOCYTIC_2	215	218	PF00928	0.684
TRG_ER_diArg_1	221	223	PF00400	0.628
TRG_ER_diArg_1	297	300	PF00400	0.445

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGY1	Leishmania donovani	88%	100%
A4HQK7	Leishmania braziliensis	69%	100%
A4ICC7	Leishmania infantum	88%	100%
Q4Q068	Leishmania major	88%	100%