CID domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AU80_LEIMU

TriTrypDb:

LmxM.36.6440

Length:

308

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AU80

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AU80

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	136	140	PF00656	0.521
CLV_NRD_NRD_1	215	217	PF00675	0.582
CLV_NRD_NRD_1	221	223	PF00675	0.518
CLV_NRD_NRD_1	8	10	PF00675	0.449
CLV_PCSK_KEX2_1	215	217	PF00082	0.606
CLV_PCSK_KEX2_1	79	81	PF00082	0.429
CLV_PCSK_KEX2_1	8	10	PF00082	0.449
CLV_PCSK_PC1ET2_1	79	81	PF00082	0.429
CLV_PCSK_SKI1_1	175	179	PF00082	0.634
CLV_PCSK_SKI1_1	80	84	PF00082	0.405
DEG_APCC_DBOX_1	214	222	PF00400	0.510
DEG_APCC_DBOX_1	54	62	PF00400	0.365
DEG_APCC_DBOX_1	79	87	PF00400	0.430
DEG_Nend_UBRbox_3	1	3	PF02207	0.502
DEG_SPOP_SBC_1	263	267	PF00917	0.563
DOC_ANK_TNKS_1	221	228	PF00023	0.309
DOC_MAPK_gen_1	215	221	PF00069	0.591
DOC_PP1_SILK_1	80	85	PF00149	0.486
DOC_PP2B_LxvP_1	88	91	PF13499	0.511
DOC_USP7_MATH_1	203	207	PF00917	0.619
DOC_USP7_MATH_1	276	280	PF00917	0.770
DOC_USP7_MATH_1	78	82	PF00917	0.501
DOC_WW_Pin1_4	264	269	PF00397	0.784
LIG_14-3-3_CanoR_1	147	151	PF00244	0.710
LIG_14-3-3_CanoR_1	249	259	PF00244	0.766
LIG_14-3-3_CanoR_1	55	59	PF00244	0.418
LIG_14-3-3_CanoR_1	99	109	PF00244	0.598
LIG_deltaCOP1_diTrp_1	117	125	PF00928	0.553
LIG_EH1_1	59	67	PF00400	0.474
LIG_eIF4E_1	60	66	PF01652	0.432
LIG_FHA_1	104	110	PF00498	0.567
LIG_FHA_1	15	21	PF00498	0.561
LIG_FHA_1	69	75	PF00498	0.601
LIG_FHA_2	134	140	PF00498	0.592
LIG_FHA_2	279	285	PF00498	0.505
LIG_GBD_Chelix_1	58	66	PF00786	0.502
LIG_LIR_Gen_1	25	34	PF02991	0.463
LIG_LIR_Nem_3	116	122	PF02991	0.438
LIG_LIR_Nem_3	25	29	PF02991	0.466
LIG_Pex14_2	125	129	PF04695	0.407
LIG_SH2_SRC	164	167	PF00017	0.588
LIG_SH2_SRC	60	63	PF00017	0.502
LIG_SH2_STAT5	280	283	PF00017	0.509
LIG_SH2_STAT5	40	43	PF00017	0.543
LIG_SH2_STAT5	60	63	PF00017	0.428
LIG_SH3_3	265	271	PF00018	0.751
LIG_UBA3_1	109	114	PF00899	0.542
LIG_UBA3_1	218	223	PF00899	0.592
LIG_WRC_WIRS_1	303	308	PF05994	0.710
MOD_CK1_1	103	109	PF00069	0.565
MOD_CK1_1	278	284	PF00069	0.769
MOD_CK1_1	68	74	PF00069	0.586
MOD_CK2_1	278	284	PF00069	0.601
MOD_GlcNHglycan	151	154	PF01048	0.575
MOD_GlcNHglycan	185	188	PF01048	0.721
MOD_GlcNHglycan	189	192	PF01048	0.732
MOD_GlcNHglycan	206	209	PF01048	0.508
MOD_GlcNHglycan	253	256	PF01048	0.720
MOD_GlcNHglycan	292	295	PF01048	0.722
MOD_GlcNHglycan	91	94	PF01048	0.544
MOD_GSK3_1	141	148	PF00069	0.548
MOD_GSK3_1	183	190	PF00069	0.726
MOD_GSK3_1	247	254	PF00069	0.638
MOD_GSK3_1	274	281	PF00069	0.795
MOD_GSK3_1	68	75	PF00069	0.600
MOD_N-GLC_1	173	178	PF02516	0.584
MOD_N-GLC_1	48	53	PF02516	0.352
MOD_NEK2_1	133	138	PF00069	0.539
MOD_NEK2_1	262	267	PF00069	0.606
MOD_NEK2_1	65	70	PF00069	0.388
MOD_PKA_2	100	106	PF00069	0.577
MOD_PKA_2	146	152	PF00069	0.674
MOD_PKA_2	248	254	PF00069	0.740
MOD_PKA_2	47	53	PF00069	0.558
MOD_PKA_2	54	60	PF00069	0.480
MOD_Plk_1	103	109	PF00069	0.565
MOD_Plk_1	173	179	PF00069	0.376
MOD_Plk_4	302	308	PF00069	0.710
MOD_Plk_4	54	60	PF00069	0.475
MOD_ProDKin_1	264	270	PF00069	0.781
MOD_SUMO_for_1	177	180	PF00179	0.606
MOD_SUMO_for_1	282	285	PF00179	0.796
TRG_ER_diArg_1	8	10	PF00400	0.449
TRG_ER_diArg_1	98	101	PF00400	0.570

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IY70	Bodo saltans	29%	100%
A0A1X0NLM3	Trypanosomatidae	29%	100%
A0A3Q8IGT5	Leishmania donovani	92%	100%
A0A3R7NPS1	Trypanosoma rangeli	36%	100%
A4HQG4	Leishmania braziliensis	84%	100%
A4ICA0	Leishmania infantum	92%	100%
D0A3L5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
Q4Q0B4	Leishmania major	92%	100%
V5D8U2	Trypanosoma cruzi	33%	100%