Sucraseferredoxin-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Sucrase/ferredoxin-like, putative

Species:

Leishmania mexicana

UniProt:

E9AU53_LEIMU

TriTrypDb:

LmxM.36.6180

Length:

257

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	2
GO:0016020	membrane	2	1

Expansion

Sequence features

E9AU53

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AU53

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	175	179	PF00082	0.422
DOC_MAPK_gen_1	245	254	PF00069	0.299
LIG_14-3-3_CanoR_1	13	21	PF00244	0.548
LIG_14-3-3_CanoR_1	189	193	PF00244	0.401
LIG_eIF4E_1	165	171	PF01652	0.286
LIG_FHA_1	138	144	PF00498	0.449
LIG_FHA_1	16	22	PF00498	0.278
LIG_FHA_1	70	76	PF00498	0.312
LIG_FHA_2	18	24	PF00498	0.450
LIG_LIR_Apic_2	128	134	PF02991	0.424
LIG_LIR_Gen_1	148	157	PF02991	0.381
LIG_LIR_Gen_1	8	16	PF02991	0.549
LIG_LIR_Nem_3	122	127	PF02991	0.318
LIG_LIR_Nem_3	146	152	PF02991	0.293
LIG_LIR_Nem_3	8	12	PF02991	0.545
LIG_SH2_CRK	124	128	PF00017	0.317
LIG_SH2_STAT5	149	152	PF00017	0.371
LIG_SH2_STAT5	165	168	PF00017	0.183
LIG_SH3_3	124	130	PF00018	0.409
LIG_SUMO_SIM_par_1	139	144	PF11976	0.354
LIG_TYR_ITSM	120	127	PF00017	0.321
MOD_CK1_1	125	131	PF00069	0.343
MOD_CK1_1	155	161	PF00069	0.375
MOD_CK2_1	49	55	PF00069	0.525
MOD_GlcNHglycan	124	127	PF01048	0.324
MOD_GlcNHglycan	144	148	PF01048	0.320
MOD_GlcNHglycan	254	257	PF01048	0.383
MOD_GSK3_1	1	8	PF00069	0.556
MOD_N-GLC_1	94	99	PF02516	0.287
MOD_NEK2_1	152	157	PF00069	0.343
MOD_NEK2_1	252	257	PF00069	0.427
MOD_NEK2_1	58	63	PF00069	0.379
MOD_NEK2_1	94	99	PF00069	0.352
MOD_NEK2_2	49	54	PF00069	0.447
MOD_PIKK_1	119	125	PF00454	0.292
MOD_PIKK_1	15	21	PF00454	0.343
MOD_PKA_2	188	194	PF00069	0.373
MOD_Plk_1	103	109	PF00069	0.318
MOD_Plk_1	94	100	PF00069	0.440
MOD_Plk_2-3	100	106	PF00069	0.304
MOD_Plk_2-3	5	11	PF00069	0.553
MOD_Plk_4	103	109	PF00069	0.344
MOD_Plk_4	165	171	PF00069	0.388
MOD_SUMO_for_1	221	224	PF00179	0.424
MOD_SUMO_rev_2	113	119	PF00179	0.358
MOD_SUMO_rev_2	132	140	PF00179	0.389
MOD_SUMO_rev_2	231	239	PF00179	0.310
TRG_DiLeu_BaEn_2	147	153	PF01217	0.302
TRG_ENDOCYTIC_2	124	127	PF00928	0.317
TRG_ENDOCYTIC_2	149	152	PF00928	0.424
TRG_ENDOCYTIC_2	218	221	PF00928	0.436
TRG_NES_CRM1_1	132	144	PF08389	0.304

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8U1	Leptomonas seymouri	40%	97%
A0A0N1I8X6	Leptomonas seymouri	74%	100%
A0A0S4JXX0	Bodo saltans	44%	98%
A0A1X0NM84	Trypanosomatidae	47%	99%
A0A3Q8IGR7	Leishmania donovani	94%	95%
A0A422NAD6	Trypanosoma rangeli	46%	100%
A4HQD8	Leishmania braziliensis	82%	100%
A4IE29	Leishmania infantum	94%	95%
D0A3V9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	90%
Q4Q0E2	Leishmania major	92%	100%
V5DJZ4	Trypanosoma cruzi	48%	78%