Galactose oxidase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Galactose oxidase

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AU52_LEIMU

TriTrypDb:

LmxM.36.6170

Length:

485

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AU52

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AU52

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	123	125	PF00675	0.708
CLV_PCSK_KEX2_1	123	125	PF00082	0.708
CLV_PCSK_KEX2_1	22	24	PF00082	0.807
CLV_PCSK_KEX2_1	478	480	PF00082	0.791
CLV_PCSK_PC1ET2_1	22	24	PF00082	0.807
CLV_PCSK_PC1ET2_1	478	480	PF00082	0.791
CLV_PCSK_SKI1_1	442	446	PF00082	0.589
DEG_SPOP_SBC_1	34	38	PF00917	0.409
DEG_SPOP_SBC_1	40	44	PF00917	0.338
DOC_CKS1_1	352	357	PF01111	0.397
DOC_CYCLIN_RxL_1	439	449	PF00134	0.674
DOC_MAPK_gen_1	169	179	PF00069	0.347
DOC_MAPK_MEF2A_6	261	270	PF00069	0.341
DOC_MAPK_MEF2A_6	461	469	PF00069	0.747
DOC_PP1_RVXF_1	440	447	PF00149	0.670
DOC_PP4_FxxP_1	195	198	PF00568	0.346
DOC_USP7_MATH_1	211	215	PF00917	0.643
DOC_USP7_MATH_1	224	228	PF00917	0.532
DOC_USP7_MATH_1	376	380	PF00917	0.723
DOC_USP7_MATH_1	410	414	PF00917	0.730
DOC_USP7_MATH_1	415	419	PF00917	0.757
DOC_USP7_MATH_1	89	93	PF00917	0.499
DOC_USP7_MATH_1	98	102	PF00917	0.519
DOC_USP7_UBL2_3	18	22	PF12436	0.795
DOC_WW_Pin1_4	133	138	PF00397	0.718
DOC_WW_Pin1_4	148	153	PF00397	0.572
DOC_WW_Pin1_4	16	21	PF00397	0.571
DOC_WW_Pin1_4	202	207	PF00397	0.676
DOC_WW_Pin1_4	278	283	PF00397	0.408
DOC_WW_Pin1_4	332	337	PF00397	0.570
DOC_WW_Pin1_4	351	356	PF00397	0.383
LIG_14-3-3_CanoR_1	147	152	PF00244	0.724
LIG_14-3-3_CanoR_1	156	164	PF00244	0.715
LIG_14-3-3_CanoR_1	178	184	PF00244	0.529
LIG_14-3-3_CanoR_1	201	206	PF00244	0.627
LIG_14-3-3_CanoR_1	23	33	PF00244	0.759
LIG_14-3-3_CanoR_1	349	355	PF00244	0.545
LIG_14-3-3_CanoR_1	392	401	PF00244	0.608
LIG_14-3-3_CanoR_1	414	420	PF00244	0.766
LIG_Actin_WH2_2	265	281	PF00022	0.579
LIG_BIR_II_1	1	5	PF00653	0.610
LIG_CSL_BTD_1	333	336	PF09270	0.580
LIG_CtBP_PxDLS_1	137	141	PF00389	0.797
LIG_deltaCOP1_diTrp_1	258	263	PF00928	0.539
LIG_FHA_1	251	257	PF00498	0.553
LIG_FHA_1	279	285	PF00498	0.417
LIG_FHA_1	310	316	PF00498	0.590
LIG_FHA_1	34	40	PF00498	0.599
LIG_FHA_1	59	65	PF00498	0.623
LIG_FHA_2	236	242	PF00498	0.663
LIG_LIR_Gen_1	2	13	PF02991	0.491
LIG_LIR_Gen_1	367	376	PF02991	0.616
LIG_LIR_Gen_1	75	86	PF02991	0.452
LIG_LIR_Nem_3	2	8	PF02991	0.488
LIG_LIR_Nem_3	333	337	PF02991	0.576
LIG_LIR_Nem_3	367	372	PF02991	0.493
LIG_LIR_Nem_3	430	435	PF02991	0.707
LIG_LIR_Nem_3	75	81	PF02991	0.461
LIG_NRP_CendR_1	483	485	PF00754	0.808
LIG_Pex14_1	334	338	PF04695	0.582
LIG_SH2_CRK	5	9	PF00017	0.489
LIG_SH2_NCK_1	13	17	PF00017	0.775
LIG_SH2_SRC	13	16	PF00017	0.775
LIG_SH2_STAP1	13	17	PF00017	0.775
LIG_SH2_STAP1	164	168	PF00017	0.425
LIG_SH2_STAP1	67	71	PF00017	0.573
LIG_SH2_STAT5	245	248	PF00017	0.456
LIG_SH2_STAT5	369	372	PF00017	0.435
LIG_SH3_2	82	87	PF14604	0.608
LIG_SH3_3	119	125	PF00018	0.488
LIG_SH3_3	131	137	PF00018	0.674
LIG_SH3_3	203	209	PF00018	0.636
LIG_SH3_3	28	34	PF00018	0.662
LIG_SH3_3	333	339	PF00018	0.506
LIG_SH3_3	352	358	PF00018	0.343
LIG_SH3_3	79	85	PF00018	0.498
LIG_TYR_ITIM	65	70	PF00017	0.567
LIG_UBA3_1	444	448	PF00899	0.405
MOD_CDC14_SPxK_1	19	22	PF00782	0.524
MOD_CDK_SPxK_1	16	22	PF00069	0.520
MOD_CDK_SPxxK_3	16	23	PF00069	0.520
MOD_CK1_1	136	142	PF00069	0.796
MOD_CK1_1	196	202	PF00069	0.482
MOD_CK1_1	205	211	PF00069	0.794
MOD_CK1_1	309	315	PF00069	0.589
MOD_CK1_1	327	333	PF00069	0.596
MOD_CK1_1	413	419	PF00069	0.792
MOD_CK2_1	235	241	PF00069	0.685
MOD_CK2_1	35	41	PF00069	0.496
MOD_CK2_1	4	10	PF00069	0.759
MOD_CMANNOS	260	263	PF00535	0.536
MOD_GlcNHglycan	113	116	PF01048	0.357
MOD_GlcNHglycan	130	133	PF01048	0.619
MOD_GlcNHglycan	153	156	PF01048	0.640
MOD_GlcNHglycan	179	182	PF01048	0.557
MOD_GlcNHglycan	195	198	PF01048	0.367
MOD_GlcNHglycan	217	220	PF01048	0.736
MOD_GlcNHglycan	226	229	PF01048	0.644
MOD_GlcNHglycan	231	234	PF01048	0.620
MOD_GlcNHglycan	329	332	PF01048	0.604
MOD_GlcNHglycan	449	452	PF01048	0.605
MOD_GlcNHglycan	91	94	PF01048	0.555
MOD_GSK3_1	146	153	PF00069	0.691
MOD_GSK3_1	201	208	PF00069	0.681
MOD_GSK3_1	211	218	PF00069	0.734
MOD_GSK3_1	35	42	PF00069	0.668
MOD_GSK3_1	409	416	PF00069	0.696
MOD_GSK3_1	453	460	PF00069	0.701
MOD_GSK3_1	474	481	PF00069	0.726
MOD_GSK3_1	72	79	PF00069	0.463
MOD_N-GLC_1	249	254	PF02516	0.580
MOD_N-GLC_1	350	355	PF02516	0.699
MOD_NEK2_1	193	198	PF00069	0.606
MOD_NEK2_1	393	398	PF00069	0.511
MOD_NEK2_1	4	9	PF00069	0.487
MOD_NEK2_1	419	424	PF00069	0.555
MOD_NEK2_1	447	452	PF00069	0.597
MOD_NEK2_1	471	476	PF00069	0.725
MOD_NEK2_2	415	420	PF00069	0.800
MOD_PIKK_1	24	30	PF00454	0.665
MOD_PIKK_1	455	461	PF00454	0.787
MOD_PIKK_1	58	64	PF00454	0.534
MOD_PKA_1	478	484	PF00069	0.526
MOD_PKA_2	146	152	PF00069	0.726
MOD_PKA_2	157	163	PF00069	0.710
MOD_PKA_2	177	183	PF00069	0.329
MOD_PKA_2	386	392	PF00069	0.373
MOD_PKA_2	413	419	PF00069	0.759
MOD_PKA_2	478	484	PF00069	0.526
MOD_Plk_1	325	331	PF00069	0.528
MOD_Plk_1	40	46	PF00069	0.615
MOD_Plk_4	226	232	PF00069	0.755
MOD_Plk_4	319	325	PF00069	0.573
MOD_Plk_4	35	41	PF00069	0.496
MOD_Plk_4	364	370	PF00069	0.492
MOD_Plk_4	386	392	PF00069	0.373
MOD_Plk_4	98	104	PF00069	0.603
MOD_ProDKin_1	133	139	PF00069	0.719
MOD_ProDKin_1	148	154	PF00069	0.574
MOD_ProDKin_1	16	22	PF00069	0.574
MOD_ProDKin_1	202	208	PF00069	0.682
MOD_ProDKin_1	278	284	PF00069	0.410
MOD_ProDKin_1	332	338	PF00069	0.579
MOD_ProDKin_1	351	357	PF00069	0.371
MOD_SUMO_rev_2	402	411	PF00179	0.457
MOD_SUMO_rev_2	468	477	PF00179	0.667
TRG_DiLeu_BaEn_2	47	53	PF01217	0.605
TRG_ENDOCYTIC_2	369	372	PF00928	0.498
TRG_ENDOCYTIC_2	5	8	PF00928	0.545
TRG_ENDOCYTIC_2	67	70	PF00928	0.573
TRG_ER_diArg_1	122	124	PF00400	0.661

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7XC07	Leishmania donovani	83%	100%
A4IE28	Leishmania infantum	83%	100%
D0A3W0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
Q4Q0E3	Leishmania major	84%	100%