RanBD1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AU51_LEIMU

TriTrypDb:

LmxM.36.6160

Length:

325

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005643	nuclear pore	3	1
GO:0032991	protein-containing complex	1	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

E9AU51

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AU51

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0008104	protein localization	4	1
GO:0009987	cellular process	1	1
GO:0015031	protein transport	4	1
GO:0015931	nucleobase-containing compound transport	5	1
GO:0033036	macromolecule localization	2	1
GO:0045184	establishment of protein localization	3	1
GO:0046907	intracellular transport	3	1
GO:0050657	nucleic acid transport	6	1
GO:0050658	RNA transport	4	1
GO:0051028	mRNA transport	5	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0051236	establishment of RNA localization	3	1
GO:0051641	cellular localization	2	1
GO:0051649	establishment of localization in cell	3	1
GO:0070727	cellular macromolecule localization	3	1
GO:0071702	organic substance transport	4	1
GO:0071705	nitrogen compound transport	4	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.789
CLV_C14_Caspase3-7	187	191	PF00656	0.662
CLV_NRD_NRD_1	159	161	PF00675	0.767
CLV_PCSK_SKI1_1	204	208	PF00082	0.603
CLV_PCSK_SKI1_1	268	272	PF00082	0.595
DEG_SPOP_SBC_1	21	25	PF00917	0.726
DOC_CYCLIN_RxL_1	265	274	PF00134	0.647
DOC_MAPK_gen_1	243	251	PF00069	0.712
DOC_MAPK_MEF2A_6	243	251	PF00069	0.442
DOC_PP4_FxxP_1	18	21	PF00568	0.805
DOC_PP4_FxxP_1	298	301	PF00568	0.579
DOC_PP4_FxxP_1	32	35	PF00568	0.603
DOC_USP7_MATH_1	152	156	PF00917	0.691
DOC_USP7_MATH_1	21	25	PF00917	0.712
DOC_USP7_MATH_1	72	76	PF00917	0.687
DOC_USP7_UBL2_3	275	279	PF12436	0.560
DOC_WW_Pin1_4	105	110	PF00397	0.841
DOC_WW_Pin1_4	221	226	PF00397	0.714
DOC_WW_Pin1_4	57	62	PF00397	0.611
DOC_WW_Pin1_4	95	100	PF00397	0.739
LIG_14-3-3_CanoR_1	80	86	PF00244	0.541
LIG_BIR_III_4	188	192	PF00653	0.750
LIG_BRCT_BRCA1_1	145	149	PF00533	0.763
LIG_BRCT_BRCA1_1	28	32	PF00533	0.824
LIG_BRCT_BRCA1_1	83	87	PF00533	0.665
LIG_BRCT_BRCA1_1	99	103	PF00533	0.633
LIG_FHA_1	291	297	PF00498	0.553
LIG_FHA_1	58	64	PF00498	0.770
LIG_FHA_2	115	121	PF00498	0.669
LIG_LIR_Apic_2	17	21	PF02991	0.803
LIG_LIR_Apic_2	29	35	PF02991	0.691
LIG_LIR_Nem_3	66	70	PF02991	0.753
LIG_MLH1_MIPbox_1	28	32	PF16413	0.558
LIG_Pex14_2	103	107	PF04695	0.784
LIG_SH2_STAP1	260	264	PF00017	0.571
LIG_SH2_STAT5	215	218	PF00017	0.556
LIG_SH2_STAT5	294	297	PF00017	0.507
LIG_SH2_STAT5	31	34	PF00017	0.563
LIG_SH3_3	134	140	PF00018	0.718
LIG_SH3_3	58	64	PF00018	0.808
LIG_SUMO_SIM_par_1	281	289	PF11976	0.572
LIG_UBA3_1	270	275	PF00899	0.644
LIG_WRC_WIRS_1	153	158	PF05994	0.692
MOD_CDK_SPK_2	57	62	PF00069	0.698
MOD_CDK_SPxK_1	105	111	PF00069	0.561
MOD_CDK_SPxK_1	221	227	PF00069	0.713
MOD_CK1_1	112	118	PF00069	0.797
MOD_CK1_1	23	29	PF00069	0.792
MOD_CK1_1	41	47	PF00069	0.771
MOD_CK1_1	48	54	PF00069	0.764
MOD_CK1_1	57	63	PF00069	0.541
MOD_CK1_1	76	82	PF00069	0.715
MOD_CK1_1	83	89	PF00069	0.691
MOD_CK1_1	9	15	PF00069	0.700
MOD_CK1_1	97	103	PF00069	0.646
MOD_CK2_1	114	120	PF00069	0.668
MOD_CK2_1	152	158	PF00069	0.696
MOD_CK2_1	271	277	PF00069	0.569
MOD_GlcNHglycan	132	135	PF01048	0.825
MOD_GlcNHglycan	200	204	PF01048	0.742
MOD_GlcNHglycan	40	43	PF01048	0.678
MOD_GlcNHglycan	51	54	PF01048	0.643
MOD_GlcNHglycan	75	78	PF01048	0.698
MOD_GlcNHglycan	99	102	PF01048	0.669
MOD_GSK3_1	101	108	PF00069	0.633
MOD_GSK3_1	189	196	PF00069	0.721
MOD_GSK3_1	21	28	PF00069	0.753
MOD_GSK3_1	269	276	PF00069	0.557
MOD_GSK3_1	304	311	PF00069	0.564
MOD_GSK3_1	34	41	PF00069	0.630
MOD_GSK3_1	45	52	PF00069	0.710
MOD_GSK3_1	72	79	PF00069	0.698
MOD_GSK3_1	90	97	PF00069	0.731
MOD_N-GLC_1	262	267	PF02516	0.552
MOD_N-GLC_1	305	310	PF02516	0.564
MOD_N-GLC_1	89	94	PF02516	0.545
MOD_NEK2_1	262	267	PF00069	0.515
MOD_NEK2_1	271	276	PF00069	0.464
MOD_NEK2_1	296	301	PF00069	0.571
MOD_NEK2_1	45	50	PF00069	0.777
MOD_PIKK_1	23	29	PF00454	0.818
MOD_PIKK_1	35	41	PF00454	0.601
MOD_PKA_2	79	85	PF00069	0.687
MOD_Plk_1	262	268	PF00069	0.561
MOD_Plk_1	89	95	PF00069	0.567
MOD_Plk_4	152	158	PF00069	0.689
MOD_Plk_4	26	32	PF00069	0.550
MOD_Plk_4	290	296	PF00069	0.510
MOD_ProDKin_1	105	111	PF00069	0.844
MOD_ProDKin_1	221	227	PF00069	0.713
MOD_ProDKin_1	57	63	PF00069	0.608
MOD_ProDKin_1	95	101	PF00069	0.739
MOD_SUMO_rev_2	172	182	PF00179	0.604
MOD_SUMO_rev_2	230	239	PF00179	0.661
MOD_SUMO_rev_2	241	245	PF00179	0.642
MOD_SUMO_rev_2	274	281	PF00179	0.551
TRG_DiLeu_BaEn_1	277	282	PF01217	0.551
TRG_DiLeu_BaLyEn_6	250	255	PF01217	0.545
TRG_NLS_MonoExtC_3	159	165	PF00514	0.782

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFC6	Leptomonas seymouri	55%	77%
A0A0S4IHX6	Bodo saltans	28%	92%
A0A3Q8IWI8	Leishmania donovani	89%	100%
A4HQD5	Leishmania braziliensis	69%	100%
A4IE27	Leishmania infantum	89%	100%
Q4Q0E4	Leishmania major	89%	99%