Mkiaa0324 protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mkiaa0324 protein-like protein

Species:

Leishmania mexicana

UniProt:

E9AU16_LEIMU

TriTrypDb:

LmxM.36.5820

Length:

500

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AU16

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AU16

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	103	105	PF00675	0.667
CLV_NRD_NRD_1	110	112	PF00675	0.594
CLV_NRD_NRD_1	12	14	PF00675	0.477
CLV_NRD_NRD_1	132	134	PF00675	0.523
CLV_NRD_NRD_1	183	185	PF00675	0.579
CLV_NRD_NRD_1	193	195	PF00675	0.577
CLV_NRD_NRD_1	199	201	PF00675	0.599
CLV_NRD_NRD_1	211	213	PF00675	0.623
CLV_NRD_NRD_1	220	222	PF00675	0.617
CLV_NRD_NRD_1	254	256	PF00675	0.580
CLV_NRD_NRD_1	294	296	PF00675	0.722
CLV_NRD_NRD_1	302	304	PF00675	0.621
CLV_NRD_NRD_1	323	325	PF00675	0.732
CLV_NRD_NRD_1	33	35	PF00675	0.508
CLV_NRD_NRD_1	331	333	PF00675	0.667
CLV_NRD_NRD_1	376	378	PF00675	0.619
CLV_NRD_NRD_1	404	406	PF00675	0.644
CLV_NRD_NRD_1	484	486	PF00675	0.471
CLV_NRD_NRD_1	84	86	PF00675	0.519
CLV_PCSK_FUR_1	108	112	PF00082	0.517
CLV_PCSK_FUR_1	194	198	PF00082	0.570
CLV_PCSK_FUR_1	243	247	PF00082	0.555
CLV_PCSK_KEX2_1	103	105	PF00082	0.684
CLV_PCSK_KEX2_1	110	112	PF00082	0.731
CLV_PCSK_KEX2_1	12	14	PF00082	0.549
CLV_PCSK_KEX2_1	132	134	PF00082	0.523
CLV_PCSK_KEX2_1	144	146	PF00082	0.378
CLV_PCSK_KEX2_1	163	165	PF00082	0.430
CLV_PCSK_KEX2_1	192	194	PF00082	0.634
CLV_PCSK_KEX2_1	196	198	PF00082	0.577
CLV_PCSK_KEX2_1	219	221	PF00082	0.558
CLV_PCSK_KEX2_1	242	244	PF00082	0.536
CLV_PCSK_KEX2_1	245	247	PF00082	0.549
CLV_PCSK_KEX2_1	254	256	PF00082	0.549
CLV_PCSK_KEX2_1	258	260	PF00082	0.556
CLV_PCSK_KEX2_1	274	276	PF00082	0.505
CLV_PCSK_KEX2_1	301	303	PF00082	0.640
CLV_PCSK_KEX2_1	323	325	PF00082	0.649
CLV_PCSK_KEX2_1	330	332	PF00082	0.646
CLV_PCSK_KEX2_1	376	378	PF00082	0.619
CLV_PCSK_KEX2_1	387	389	PF00082	0.446
CLV_PCSK_KEX2_1	406	408	PF00082	0.588
CLV_PCSK_KEX2_1	484	486	PF00082	0.641
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.620
CLV_PCSK_PC1ET2_1	144	146	PF00082	0.502
CLV_PCSK_PC1ET2_1	163	165	PF00082	0.430
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.611
CLV_PCSK_PC1ET2_1	219	221	PF00082	0.558
CLV_PCSK_PC1ET2_1	242	244	PF00082	0.519
CLV_PCSK_PC1ET2_1	245	247	PF00082	0.503
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.558
CLV_PCSK_PC1ET2_1	274	276	PF00082	0.715
CLV_PCSK_PC1ET2_1	301	303	PF00082	0.633
CLV_PCSK_PC1ET2_1	323	325	PF00082	0.784
CLV_PCSK_PC1ET2_1	387	389	PF00082	0.490
CLV_PCSK_PC1ET2_1	406	408	PF00082	0.588
CLV_PCSK_PC7_1	140	146	PF00082	0.459
CLV_PCSK_PC7_1	192	198	PF00082	0.608
CLV_PCSK_PC7_1	254	260	PF00082	0.623
CLV_PCSK_PC7_1	327	333	PF00082	0.501
CLV_PCSK_SKI1_1	118	122	PF00082	0.584
CLV_PCSK_SKI1_1	144	148	PF00082	0.515
CLV_PCSK_SKI1_1	196	200	PF00082	0.609
CLV_PCSK_SKI1_1	201	205	PF00082	0.570
CLV_PCSK_SKI1_1	213	217	PF00082	0.696
CLV_PCSK_SKI1_1	220	224	PF00082	0.709
CLV_PCSK_SKI1_1	228	232	PF00082	0.522
CLV_PCSK_SKI1_1	242	246	PF00082	0.513
CLV_PCSK_SKI1_1	279	283	PF00082	0.654
CLV_PCSK_SKI1_1	359	363	PF00082	0.477
CLV_PCSK_SKI1_1	435	439	PF00082	0.442
CLV_PCSK_SKI1_1	485	489	PF00082	0.455
CLV_PCSK_SKI1_1	71	75	PF00082	0.442
CLV_PCSK_SKI1_1	79	83	PF00082	0.522
CLV_Separin_Metazoa	129	133	PF03568	0.504
DEG_APCC_DBOX_1	139	147	PF00400	0.462
DEG_Nend_Nbox_1	1	3	PF02207	0.539
DEG_SCF_FBW7_1	119	125	PF00400	0.359
DOC_CKS1_1	119	124	PF01111	0.363
DOC_MAPK_DCC_7	392	402	PF00069	0.413
DOC_MAPK_gen_1	103	109	PF00069	0.588
DOC_MAPK_gen_1	144	151	PF00069	0.501
DOC_MAPK_gen_1	163	171	PF00069	0.441
DOC_MAPK_gen_1	254	265	PF00069	0.618
DOC_MAPK_gen_1	330	339	PF00069	0.501
DOC_MAPK_MEF2A_6	163	171	PF00069	0.437
DOC_MAPK_MEF2A_6	258	267	PF00069	0.630
DOC_MAPK_MEF2A_6	330	339	PF00069	0.501
DOC_MAPK_MEF2A_6	394	402	PF00069	0.422
DOC_MAPK_RevD_3	261	275	PF00069	0.642
DOC_PP2B_LxvP_1	159	162	PF13499	0.598
DOC_PP4_FxxP_1	54	57	PF00568	0.418
DOC_USP7_MATH_1	122	126	PF00917	0.344
DOC_USP7_MATH_1	15	19	PF00917	0.421
DOC_USP7_MATH_1	203	207	PF00917	0.636
DOC_USP7_MATH_1	214	218	PF00917	0.575
DOC_USP7_MATH_1	233	237	PF00917	0.605
DOC_USP7_MATH_1	273	277	PF00917	0.692
DOC_USP7_MATH_1	297	301	PF00917	0.646
DOC_USP7_MATH_1	476	480	PF00917	0.377
DOC_USP7_MATH_1	8	12	PF00917	0.573
DOC_USP7_MATH_1	89	93	PF00917	0.622
DOC_USP7_UBL2_3	185	189	PF12436	0.517
DOC_USP7_UBL2_3	71	75	PF12436	0.472
DOC_USP7_UBL2_3	82	86	PF12436	0.514
DOC_WW_Pin1_4	118	123	PF00397	0.484
DOC_WW_Pin1_4	411	416	PF00397	0.737
LIG_14-3-3_CanoR_1	133	143	PF00244	0.380
LIG_14-3-3_CanoR_1	221	230	PF00244	0.580
LIG_14-3-3_CanoR_1	234	244	PF00244	0.604
LIG_14-3-3_CanoR_1	259	264	PF00244	0.639
LIG_14-3-3_CanoR_1	308	313	PF00244	0.556
LIG_14-3-3_CanoR_1	34	43	PF00244	0.453
LIG_14-3-3_CanoR_1	405	415	PF00244	0.563
LIG_14-3-3_CanoR_1	477	481	PF00244	0.524
LIG_14-3-3_CanoR_1	484	491	PF00244	0.428
LIG_14-3-3_CanoR_1	53	57	PF00244	0.424
LIG_14-3-3_CanoR_1	98	102	PF00244	0.528
LIG_BRCT_BRCA1_1	444	448	PF00533	0.460
LIG_EH_1	445	449	PF12763	0.414
LIG_FHA_1	197	203	PF00498	0.543
LIG_FHA_1	344	350	PF00498	0.451
LIG_FHA_1	356	362	PF00498	0.451
LIG_FHA_1	36	42	PF00498	0.444
LIG_FHA_1	366	372	PF00498	0.407
LIG_FHA_1	380	386	PF00498	0.423
LIG_FHA_1	72	78	PF00498	0.489
LIG_IBAR_NPY_1	334	336	PF08397	0.466
LIG_LIR_Gen_1	121	131	PF02991	0.448
LIG_LIR_Gen_1	451	459	PF02991	0.403
LIG_LIR_Nem_3	121	126	PF02991	0.476
LIG_LIR_Nem_3	18	23	PF02991	0.507
LIG_LIR_Nem_3	451	455	PF02991	0.384
LIG_LYPXL_S_1	23	27	PF13949	0.372
LIG_LYPXL_yS_3	24	27	PF13949	0.383
LIG_Pex14_2	16	20	PF04695	0.328
LIG_REV1ctd_RIR_1	17	24	PF16727	0.339
LIG_RPA_C_Fungi	290	302	PF08784	0.536
LIG_SH2_CRK	452	456	PF00017	0.397
LIG_SH2_STAP1	452	456	PF00017	0.397
LIG_SH2_STAT5	336	339	PF00017	0.440
LIG_SH3_1	254	260	PF00018	0.623
LIG_SH3_3	116	122	PF00018	0.402
LIG_SH3_3	20	26	PF00018	0.495
LIG_SH3_3	254	260	PF00018	0.623
LIG_SH3_3	283	289	PF00018	0.521
LIG_SH3_3	347	353	PF00018	0.491
LIG_SH3_3	392	398	PF00018	0.553
LIG_SH3_3	418	424	PF00018	0.739
LIG_SH3_4	82	89	PF00018	0.543
LIG_SUMO_SIM_anti_2	5	11	PF11976	0.387
LIG_SUMO_SIM_par_1	5	11	PF11976	0.387
LIG_WRC_WIRS_1	123	128	PF05994	0.318
LIG_WRC_WIRS_1	16	21	PF05994	0.470
LIG_WW_1	440	443	PF00397	0.455
MOD_CK1_1	125	131	PF00069	0.366
MOD_Cter_Amidation	83	86	PF01082	0.521
MOD_GlcNHglycan	205	208	PF01048	0.665
MOD_GlcNHglycan	237	240	PF01048	0.597
MOD_GlcNHglycan	275	278	PF01048	0.699
MOD_GlcNHglycan	402	405	PF01048	0.641
MOD_GlcNHglycan	485	488	PF01048	0.461
MOD_GlcNHglycan	54	57	PF01048	0.494
MOD_GSK3_1	118	125	PF00069	0.402
MOD_GSK3_1	131	138	PF00069	0.532
MOD_GSK3_1	180	187	PF00069	0.549
MOD_GSK3_1	192	199	PF00069	0.556
MOD_GSK3_1	203	210	PF00069	0.524
MOD_GSK3_1	304	311	PF00069	0.645
MOD_GSK3_1	319	326	PF00069	0.477
MOD_GSK3_1	363	370	PF00069	0.463
MOD_GSK3_1	386	393	PF00069	0.557
MOD_GSK3_1	407	414	PF00069	0.599
MOD_N-GLC_1	207	212	PF02516	0.500
MOD_NEK2_1	131	136	PF00069	0.465
MOD_NEK2_1	2	7	PF00069	0.528
MOD_NEK2_1	317	322	PF00069	0.507
MOD_NEK2_1	343	348	PF00069	0.436
MOD_NEK2_1	448	453	PF00069	0.383
MOD_NEK2_1	77	82	PF00069	0.544
MOD_NEK2_1	96	101	PF00069	0.497
MOD_NEK2_2	15	20	PF00069	0.467
MOD_NEK2_2	476	481	PF00069	0.389
MOD_PK_1	259	265	PF00069	0.651
MOD_PK_1	308	314	PF00069	0.531
MOD_PKA_1	184	190	PF00069	0.678
MOD_PKA_1	192	198	PF00069	0.657
MOD_PKA_1	220	226	PF00069	0.573
MOD_PKA_1	323	329	PF00069	0.594
MOD_PKA_1	406	412	PF00069	0.565
MOD_PKA_2	131	137	PF00069	0.559
MOD_PKA_2	192	198	PF00069	0.566
MOD_PKA_2	220	226	PF00069	0.594
MOD_PKA_2	233	239	PF00069	0.550
MOD_PKA_2	304	310	PF00069	0.558
MOD_PKA_2	317	323	PF00069	0.524
MOD_PKA_2	343	349	PF00069	0.401
MOD_PKA_2	379	385	PF00069	0.498
MOD_PKA_2	400	406	PF00069	0.645
MOD_PKA_2	476	482	PF00069	0.529
MOD_PKA_2	483	489	PF00069	0.441
MOD_PKA_2	52	58	PF00069	0.465
MOD_PKA_2	97	103	PF00069	0.627
MOD_PKB_1	405	413	PF00069	0.531
MOD_Plk_4	15	21	PF00069	0.473
MOD_ProDKin_1	118	124	PF00069	0.477
MOD_ProDKin_1	411	417	PF00069	0.737
TRG_DiLeu_BaLyEn_6	167	172	PF01217	0.433
TRG_DiLeu_BaLyEn_6	454	459	PF01217	0.555
TRG_ENDOCYTIC_2	24	27	PF00928	0.410
TRG_ENDOCYTIC_2	336	339	PF00928	0.473
TRG_ENDOCYTIC_2	340	343	PF00928	0.477
TRG_ENDOCYTIC_2	452	455	PF00928	0.390
TRG_ER_diArg_1	107	110	PF00400	0.464
TRG_ER_diArg_1	12	14	PF00400	0.438
TRG_ER_diArg_1	131	133	PF00400	0.520
TRG_ER_diArg_1	192	194	PF00400	0.572
TRG_ER_diArg_1	220	222	PF00400	0.536
TRG_ER_diArg_1	246	249	PF00400	0.619
TRG_ER_diArg_1	254	256	PF00400	0.601
TRG_ER_diArg_1	302	305	PF00400	0.653
TRG_ER_diArg_1	330	332	PF00400	0.680
TRG_ER_diArg_1	376	378	PF00400	0.619
TRG_ER_diArg_1	93	96	PF00400	0.559
TRG_NLS_Bipartite_1	200	222	PF00514	0.602
TRG_NLS_Bipartite_1	228	249	PF00514	0.595
TRG_NLS_Bipartite_1	295	309	PF00514	0.645
TRG_NLS_Bipartite_1	387	409	PF00514	0.502
TRG_NLS_Bipartite_1	85	107	PF00514	0.539
TRG_NLS_MonoCore_2	217	222	PF00514	0.597
TRG_NLS_MonoExtC_3	241	246	PF00514	0.544
TRG_NLS_MonoExtC_3	300	305	PF00514	0.656
TRG_NLS_MonoExtC_3	322	327	PF00514	0.484
TRG_NLS_MonoExtN_4	102	107	PF00514	0.606
TRG_NLS_MonoExtN_4	216	223	PF00514	0.576
TRG_NLS_MonoExtN_4	242	249	PF00514	0.562
TRG_NLS_MonoExtN_4	302	309	PF00514	0.497
TRG_NLS_MonoExtN_4	323	328	PF00514	0.548
TRG_NLS_MonoExtN_4	82	89	PF00514	0.543
TRG_Pf-PMV_PEXEL_1	170	175	PF00026	0.440

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3V1	Leptomonas seymouri	43%	100%
A0A3Q8IK24	Leishmania donovani	86%	100%
A4HQ98	Leishmania braziliensis	63%	100%
A4IDZ5	Leishmania infantum	86%	100%
Q4Q0H9	Leishmania major	85%	100%