Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Phosphoseryl-tRNA Kinase, putative

Species:

Leishmania mexicana

UniProt:

E9ATY9_LEIMU

TriTrypDb:

LmxM.36.5540

Length:

453

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 8
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATY9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATY9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0000049	tRNA binding	5	1
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0003824	catalytic activity	1	1
GO:0005488	binding	1	1
GO:0016301	kinase activity	4	1
GO:0016740	transferase activity	2	1
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	118	122	PF00656	0.423
CLV_NRD_NRD_1	102	104	PF00675	0.403
CLV_NRD_NRD_1	201	203	PF00675	0.446
CLV_NRD_NRD_1	380	382	PF00675	0.553
CLV_NRD_NRD_1	89	91	PF00675	0.618
CLV_NRD_NRD_1	98	100	PF00675	0.468
CLV_PCSK_KEX2_1	102	104	PF00082	0.521
CLV_PCSK_KEX2_1	201	203	PF00082	0.493
CLV_PCSK_KEX2_1	382	384	PF00082	0.480
CLV_PCSK_KEX2_1	98	100	PF00082	0.525
CLV_PCSK_PC1ET2_1	382	384	PF00082	0.312
CLV_PCSK_PC7_1	197	203	PF00082	0.340
CLV_PCSK_PC7_1	98	104	PF00082	0.520
CLV_PCSK_SKI1_1	109	113	PF00082	0.252
CLV_PCSK_SKI1_1	186	190	PF00082	0.503
CLV_PCSK_SKI1_1	376	380	PF00082	0.594
CLV_PCSK_SKI1_1	98	102	PF00082	0.449
DEG_APCC_DBOX_1	175	183	PF00400	0.435
DOC_CKS1_1	187	192	PF01111	0.403
DOC_CYCLIN_RxL_1	98	110	PF00134	0.507
DOC_MAPK_gen_1	98	107	PF00069	0.375
DOC_MAPK_MEF2A_6	176	183	PF00069	0.433
DOC_MAPK_MEF2A_6	186	195	PF00069	0.454
DOC_PP4_FxxP_1	187	190	PF00568	0.475
DOC_USP7_MATH_1	11	15	PF00917	0.552
DOC_USP7_MATH_1	172	176	PF00917	0.558
DOC_USP7_MATH_1	213	217	PF00917	0.634
DOC_USP7_MATH_1	26	30	PF00917	0.423
DOC_USP7_MATH_1	281	285	PF00917	0.443
DOC_USP7_MATH_1	337	341	PF00917	0.483
DOC_USP7_MATH_1	83	87	PF00917	0.492
DOC_WW_Pin1_4	186	191	PF00397	0.386
DOC_WW_Pin1_4	370	375	PF00397	0.674
DOC_WW_Pin1_4	4	9	PF00397	0.692
DOC_WW_Pin1_4	90	95	PF00397	0.536
LIG_14-3-3_CanoR_1	176	180	PF00244	0.435
LIG_14-3-3_CanoR_1	400	409	PF00244	0.512
LIG_BIR_II_1	1	5	PF00653	0.752
LIG_BIR_III_3	1	5	PF00653	0.674
LIG_CSL_BTD_1	217	220	PF09270	0.547
LIG_deltaCOP1_diTrp_1	439	444	PF00928	0.267
LIG_eIF4E_1	235	241	PF01652	0.354
LIG_FHA_1	112	118	PF00498	0.349
LIG_FHA_1	176	182	PF00498	0.366
LIG_FHA_1	235	241	PF00498	0.480
LIG_FHA_1	326	332	PF00498	0.505
LIG_FHA_1	340	346	PF00498	0.406
LIG_FHA_1	408	414	PF00498	0.610
LIG_FHA_1	99	105	PF00498	0.469
LIG_FHA_2	75	81	PF00498	0.695
LIG_HCF-1_HBM_1	232	235	PF13415	0.512
LIG_LIR_Apic_2	184	190	PF02991	0.458
LIG_LIR_Apic_2	216	221	PF02991	0.616
LIG_LIR_Nem_3	260	266	PF02991	0.423
LIG_LIR_Nem_3	439	444	PF02991	0.426
LIG_Pex14_2	183	187	PF04695	0.484
LIG_Rb_pABgroove_1	225	233	PF01858	0.513
LIG_SH2_NCK_1	235	239	PF00017	0.521
LIG_SH2_STAP1	160	164	PF00017	0.355
LIG_SH2_STAT3	160	163	PF00017	0.587
LIG_SH2_STAT3	428	431	PF00017	0.266
LIG_SH2_STAT5	428	431	PF00017	0.266
LIG_SH3_3	2	8	PF00018	0.715
LIG_SH3_3	216	222	PF00018	0.565
LIG_SH3_3	242	248	PF00018	0.679
LIG_SUMO_SIM_anti_2	178	184	PF11976	0.295
LIG_SUMO_SIM_par_1	103	108	PF11976	0.490
LIG_SUMO_SIM_par_1	178	184	PF11976	0.413
LIG_SUMO_SIM_par_1	410	416	PF11976	0.544
LIG_SxIP_EBH_1	16	28	PF03271	0.463
LIG_WW_3	373	377	PF00397	0.366
MOD_CDC14_SPxK_1	373	376	PF00782	0.374
MOD_CDK_SPK_2	90	95	PF00069	0.554
MOD_CDK_SPxK_1	370	376	PF00069	0.614
MOD_CK1_1	175	181	PF00069	0.350
MOD_CK1_1	7	13	PF00069	0.605
MOD_CK2_1	140	146	PF00069	0.497
MOD_CK2_1	205	211	PF00069	0.635
MOD_CK2_1	74	80	PF00069	0.524
MOD_CK2_1	83	89	PF00069	0.494
MOD_CMANNOS	251	254	PF00535	0.556
MOD_GlcNHglycan	109	112	PF01048	0.512
MOD_GlcNHglycan	13	16	PF01048	0.459
MOD_GlcNHglycan	206	210	PF01048	0.658
MOD_GlcNHglycan	215	218	PF01048	0.502
MOD_GlcNHglycan	402	405	PF01048	0.383
MOD_GlcNHglycan	45	48	PF01048	0.501
MOD_GlcNHglycan	85	88	PF01048	0.719
MOD_GSK3_1	107	114	PF00069	0.515
MOD_GSK3_1	154	161	PF00069	0.433
MOD_GSK3_1	3	10	PF00069	0.703
MOD_GSK3_1	365	372	PF00069	0.583
MOD_NEK2_1	105	110	PF00069	0.492
MOD_NEK2_1	18	23	PF00069	0.467
MOD_NEK2_1	325	330	PF00069	0.581
MOD_NEK2_1	409	414	PF00069	0.470
MOD_PIKK_1	257	263	PF00454	0.509
MOD_PIKK_1	267	273	PF00454	0.569
MOD_PIKK_1	443	449	PF00454	0.376
MOD_PKA_1	98	104	PF00069	0.361
MOD_PKA_2	175	181	PF00069	0.392
MOD_PKA_2	41	47	PF00069	0.549
MOD_PKA_2	98	104	PF00069	0.361
MOD_Plk_1	158	164	PF00069	0.551
MOD_Plk_1	326	332	PF00069	0.610
MOD_Plk_2-3	74	80	PF00069	0.540
MOD_Plk_4	175	181	PF00069	0.299
MOD_Plk_4	27	33	PF00069	0.493
MOD_ProDKin_1	186	192	PF00069	0.396
MOD_ProDKin_1	370	376	PF00069	0.664
MOD_ProDKin_1	4	10	PF00069	0.678
MOD_ProDKin_1	90	96	PF00069	0.522
MOD_SUMO_for_1	387	390	PF00179	0.550
MOD_SUMO_for_1	405	408	PF00179	0.528
MOD_SUMO_rev_2	86	93	PF00179	0.589
TRG_DiLeu_BaLyEn_6	100	105	PF01217	0.472
TRG_ENDOCYTIC_2	141	144	PF00928	0.404
TRG_ENDOCYTIC_2	148	151	PF00928	0.356
TRG_ER_diArg_1	102	104	PF00400	0.519
TRG_ER_diArg_1	313	316	PF00400	0.563
TRG_ER_diArg_1	380	383	PF00400	0.499
TRG_ER_diArg_1	97	99	PF00400	0.534
TRG_Pf-PMV_PEXEL_1	102	106	PF00026	0.509
TRG_Pf-PMV_PEXEL_1	153	158	PF00026	0.396

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFJ4	Leptomonas seymouri	36%	98%
A0A1X0P061	Trypanosomatidae	23%	100%
A0A3Q8ILN7	Leishmania donovani	85%	100%
A0A422NKD5	Trypanosoma rangeli	25%	100%
A4HQ70	Leishmania braziliensis	72%	100%
A4IDW8	Leishmania infantum	86%	100%
D0A449	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
Q4Q0K7	Leishmania major	85%	100%