Adiponectin receptor protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Haemolysin-III related, putative

Species:

Leishmania mexicana

UniProt:

E9ATY6_LEIMU

TriTrypDb:

LmxM.36.5510

Length:

497

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 17
NetGPI	no	yes: 0, no: 17

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	18
GO:0110165	cellular anatomical entity	1	18

Expansion

Sequence features

E9ATY6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATY6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0038023	signaling receptor activity	2	3
GO:0060089	molecular transducer activity	1	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	110	114	PF00656	0.705
CLV_C14_Caspase3-7	9	13	PF00656	0.612
CLV_NRD_NRD_1	16	18	PF00675	0.433
CLV_NRD_NRD_1	189	191	PF00675	0.516
CLV_NRD_NRD_1	388	390	PF00675	0.172
CLV_PCSK_KEX2_1	16	18	PF00082	0.433
CLV_PCSK_KEX2_1	189	191	PF00082	0.524
CLV_PCSK_SKI1_1	252	256	PF00082	0.337
CLV_PCSK_SKI1_1	288	292	PF00082	0.462
DEG_ODPH_VHL_1	407	419	PF01847	0.268
DEG_SPOP_SBC_1	135	139	PF00917	0.628
DOC_CKS1_1	85	90	PF01111	0.615
DOC_CYCLIN_yCln2_LP_2	170	176	PF00134	0.600
DOC_CYCLIN_yCln2_LP_2	74	80	PF00134	0.593
DOC_MAPK_gen_1	124	132	PF00069	0.588
DOC_MAPK_gen_1	189	195	PF00069	0.557
DOC_MAPK_gen_1	389	396	PF00069	0.395
DOC_MAPK_HePTP_8	392	404	PF00069	0.424
DOC_MAPK_MEF2A_6	336	344	PF00069	0.403
DOC_MAPK_MEF2A_6	389	398	PF00069	0.430
DOC_PP1_RVXF_1	334	340	PF00149	0.445
DOC_PP1_RVXF_1	387	394	PF00149	0.476
DOC_PP4_FxxP_1	350	353	PF00568	0.357
DOC_USP7_MATH_1	125	129	PF00917	0.678
DOC_USP7_MATH_1	135	139	PF00917	0.693
DOC_USP7_MATH_1	15	19	PF00917	0.642
DOC_USP7_MATH_1	410	414	PF00917	0.338
DOC_USP7_MATH_1	422	426	PF00917	0.221
DOC_USP7_MATH_1	78	82	PF00917	0.682
DOC_WW_Pin1_4	163	168	PF00397	0.697
DOC_WW_Pin1_4	181	186	PF00397	0.622
DOC_WW_Pin1_4	84	89	PF00397	0.683
LIG_14-3-3_CanoR_1	124	132	PF00244	0.680
LIG_14-3-3_CanoR_1	16	21	PF00244	0.727
LIG_14-3-3_CanoR_1	189	194	PF00244	0.692
LIG_14-3-3_CanoR_1	242	248	PF00244	0.504
LIG_14-3-3_CanoR_1	57	65	PF00244	0.637
LIG_BIR_II_1	1	5	PF00653	0.634
LIG_deltaCOP1_diTrp_1	458	467	PF00928	0.487
LIG_eIF4E_1	368	374	PF01652	0.295
LIG_FHA_1	143	149	PF00498	0.713
LIG_FHA_1	156	162	PF00498	0.713
LIG_FHA_1	259	265	PF00498	0.474
LIG_FHA_1	276	282	PF00498	0.333
LIG_FHA_1	341	347	PF00498	0.333
LIG_FHA_1	364	370	PF00498	0.277
LIG_FHA_1	375	381	PF00498	0.367
LIG_FHA_1	49	55	PF00498	0.623
LIG_FHA_1	80	86	PF00498	0.644
LIG_FHA_2	157	163	PF00498	0.600
LIG_FHA_2	7	13	PF00498	0.730
LIG_GBD_Chelix_1	211	219	PF00786	0.251
LIG_IBAR_NPY_1	234	236	PF08397	0.488
LIG_LIR_Apic_2	348	353	PF02991	0.359
LIG_LIR_Gen_1	188	198	PF02991	0.545
LIG_LIR_Gen_1	266	276	PF02991	0.342
LIG_LIR_LC3C_4	192	195	PF02991	0.539
LIG_LIR_Nem_3	188	194	PF02991	0.550
LIG_LIR_Nem_3	239	244	PF02991	0.561
LIG_LIR_Nem_3	248	254	PF02991	0.497
LIG_LIR_Nem_3	266	271	PF02991	0.305
LIG_LIR_Nem_3	316	322	PF02991	0.485
LIG_LIR_Nem_3	338	342	PF02991	0.334
LIG_LIR_Nem_3	385	391	PF02991	0.497
LIG_NRBOX	276	282	PF00104	0.293
LIG_PCNA_yPIPBox_3	315	329	PF02747	0.295
LIG_Pex14_1	384	388	PF04695	0.295
LIG_SH2_CRK	282	286	PF00017	0.257
LIG_SH2_STAP1	245	249	PF00017	0.451
LIG_SH2_STAP1	265	269	PF00017	0.163
LIG_SH2_STAP1	282	286	PF00017	0.319
LIG_SH2_STAT3	444	447	PF00017	0.300
LIG_SH2_STAT5	236	239	PF00017	0.578
LIG_SH2_STAT5	245	248	PF00017	0.529
LIG_SH2_STAT5	282	285	PF00017	0.278
LIG_SH2_STAT5	355	358	PF00017	0.314
LIG_SH2_STAT5	368	371	PF00017	0.374
LIG_SH2_STAT5	437	440	PF00017	0.402
LIG_SH2_STAT5	444	447	PF00017	0.317
LIG_SH2_STAT5	479	482	PF00017	0.355
LIG_SH3_3	192	198	PF00018	0.632
LIG_SH3_3	82	88	PF00018	0.670
LIG_Sin3_3	371	378	PF02671	0.249
LIG_SUMO_SIM_anti_2	343	349	PF11976	0.274
LIG_SUMO_SIM_anti_2	35	41	PF11976	0.560
LIG_SUMO_SIM_anti_2	370	377	PF11976	0.328
LIG_SUMO_SIM_anti_2	413	418	PF11976	0.340
LIG_SUMO_SIM_par_1	342	349	PF11976	0.254
LIG_SUMO_SIM_par_1	370	377	PF11976	0.352
LIG_TRFH_1	42	46	PF08558	0.574
LIG_TYR_ITIM	280	285	PF00017	0.295
LIG_Vh1_VBS_1	363	381	PF01044	0.210
LIG_WRC_WIRS_1	268	273	PF05994	0.295
LIG_WRC_WIRS_1	347	352	PF05994	0.333
LIG_WW_1	352	355	PF00397	0.295
MOD_CDK_SPK_2	163	168	PF00069	0.646
MOD_CK1_1	128	134	PF00069	0.749
MOD_CK1_1	139	145	PF00069	0.619
MOD_CK1_1	184	190	PF00069	0.590
MOD_CK1_1	423	429	PF00069	0.309
MOD_CK2_1	135	141	PF00069	0.595
MOD_CK2_1	15	21	PF00069	0.681
MOD_CK2_1	156	162	PF00069	0.661
MOD_GlcNHglycan	138	141	PF01048	0.597
MOD_GlcNHglycan	295	298	PF01048	0.424
MOD_GlcNHglycan	404	407	PF01048	0.297
MOD_GlcNHglycan	438	441	PF01048	0.281
MOD_GlcNHglycan	70	73	PF01048	0.455
MOD_GSK3_1	135	142	PF00069	0.677
MOD_GSK3_1	143	150	PF00069	0.701
MOD_GSK3_1	196	203	PF00069	0.531
MOD_GSK3_1	263	270	PF00069	0.295
MOD_GSK3_1	280	287	PF00069	0.295
MOD_GSK3_1	291	298	PF00069	0.252
MOD_GSK3_1	363	370	PF00069	0.318
MOD_N-GLC_1	258	263	PF02516	0.284
MOD_N-GLC_1	314	319	PF02516	0.252
MOD_NEK2_1	154	159	PF00069	0.607
MOD_NEK2_1	275	280	PF00069	0.381
MOD_NEK2_1	281	286	PF00069	0.330
MOD_NEK2_1	295	300	PF00069	0.294
MOD_NEK2_1	313	318	PF00069	0.317
MOD_NEK2_1	321	326	PF00069	0.489
MOD_NEK2_1	345	350	PF00069	0.370
MOD_NEK2_1	373	378	PF00069	0.372
MOD_NEK2_1	402	407	PF00069	0.303
MOD_NEK2_1	436	441	PF00069	0.471
MOD_NEK2_1	443	448	PF00069	0.359
MOD_NEK2_1	469	474	PF00069	0.296
MOD_PIKK_1	103	109	PF00454	0.654
MOD_PIKK_1	443	449	PF00454	0.249
MOD_PKA_1	16	22	PF00069	0.595
MOD_PKA_1	189	195	PF00069	0.621
MOD_PKA_2	126	132	PF00069	0.596
MOD_PKA_2	15	21	PF00069	0.631
MOD_PKA_2	189	195	PF00069	0.638
MOD_PKA_2	56	62	PF00069	0.767
MOD_Plk_1	258	264	PF00069	0.484
MOD_Plk_1	314	320	PF00069	0.252
MOD_Plk_1	6	12	PF00069	0.622
MOD_Plk_4	250	256	PF00069	0.544
MOD_Plk_4	267	273	PF00069	0.232
MOD_Plk_4	281	287	PF00069	0.365
MOD_Plk_4	306	312	PF00069	0.341
MOD_Plk_4	314	320	PF00069	0.394
MOD_Plk_4	346	352	PF00069	0.325
MOD_Plk_4	423	429	PF00069	0.294
MOD_Plk_4	481	487	PF00069	0.319
MOD_ProDKin_1	163	169	PF00069	0.699
MOD_ProDKin_1	181	187	PF00069	0.627
MOD_ProDKin_1	84	90	PF00069	0.684
TRG_AP2beta_CARGO_1	386	395	PF09066	0.372
TRG_DiLeu_BaEn_1	35	40	PF01217	0.583
TRG_DiLeu_BaEn_2	95	101	PF01217	0.655
TRG_ENDOCYTIC_2	241	244	PF00928	0.467
TRG_ENDOCYTIC_2	265	268	PF00928	0.271
TRG_ENDOCYTIC_2	282	285	PF00928	0.319
TRG_ENDOCYTIC_2	302	305	PF00928	0.297
TRG_ENDOCYTIC_2	319	322	PF00928	0.538
TRG_ENDOCYTIC_2	355	358	PF00928	0.300
TRG_ER_diArg_1	15	17	PF00400	0.620
TRG_ER_diArg_1	189	191	PF00400	0.659
TRG_ER_diArg_1	237	240	PF00400	0.464
TRG_Pf-PMV_PEXEL_1	168	172	PF00026	0.401

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEB9	Leptomonas seymouri	49%	92%
A0A3S7XBT4	Leishmania donovani	37%	100%
A0A3S7XBU6	Leishmania donovani	81%	98%
A0A3S7XC05	Leishmania donovani	38%	100%
A4HQ64	Leishmania braziliensis	66%	99%
A4HQ67	Leishmania braziliensis	34%	100%
A4HQ68	Leishmania braziliensis	39%	100%
A4IDW4	Leishmania infantum	37%	100%
A4IDW5	Leishmania infantum	81%	98%
A4IDW6	Leishmania infantum	38%	100%
E9ATY5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9ATY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
Q4Q0K9	Leishmania major	37%	100%
Q4Q0L0	Leishmania major	80%	100%
Q4Q0L1	Leishmania major	37%	100%
Q75F81	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	100%
Q8BQS5	Mus musculus	29%	100%
V5DK49	Trypanosoma cruzi	34%	100%