LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ATY3_LEIMU
TriTrypDb:
LmxM.36.5480
Length:
663

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0005829 cytosol 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9ATY3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATY3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 122 126 PF00656 0.678
CLV_NRD_NRD_1 286 288 PF00675 0.576
CLV_NRD_NRD_1 293 295 PF00675 0.433
CLV_PCSK_FUR_1 284 288 PF00082 0.522
CLV_PCSK_KEX2_1 286 288 PF00082 0.576
CLV_PCSK_KEX2_1 293 295 PF00082 0.433
CLV_PCSK_KEX2_1 301 303 PF00082 0.359
CLV_PCSK_KEX2_1 411 413 PF00082 0.641
CLV_PCSK_PC1ET2_1 301 303 PF00082 0.509
CLV_PCSK_PC1ET2_1 411 413 PF00082 0.528
CLV_PCSK_SKI1_1 391 395 PF00082 0.561
DEG_Nend_UBRbox_2 1 3 PF02207 0.688
DOC_CKS1_1 483 488 PF01111 0.539
DOC_CKS1_1 560 565 PF01111 0.671
DOC_MAPK_gen_1 298 305 PF00069 0.510
DOC_MAPK_MEF2A_6 166 173 PF00069 0.465
DOC_PP2B_LxvP_1 624 627 PF13499 0.692
DOC_PP4_FxxP_1 21 24 PF00568 0.688
DOC_PP4_FxxP_1 237 240 PF00568 0.647
DOC_PP4_FxxP_1 653 656 PF00568 0.613
DOC_USP7_MATH_1 120 124 PF00917 0.737
DOC_USP7_MATH_1 143 147 PF00917 0.736
DOC_USP7_MATH_1 211 215 PF00917 0.580
DOC_USP7_MATH_1 251 255 PF00917 0.672
DOC_USP7_MATH_1 32 36 PF00917 0.728
DOC_USP7_MATH_1 368 372 PF00917 0.519
DOC_USP7_MATH_1 532 536 PF00917 0.666
DOC_USP7_MATH_1 558 562 PF00917 0.650
DOC_USP7_MATH_1 606 610 PF00917 0.615
DOC_USP7_MATH_1 625 629 PF00917 0.533
DOC_WW_Pin1_4 149 154 PF00397 0.668
DOC_WW_Pin1_4 160 165 PF00397 0.558
DOC_WW_Pin1_4 235 240 PF00397 0.687
DOC_WW_Pin1_4 247 252 PF00397 0.629
DOC_WW_Pin1_4 476 481 PF00397 0.670
DOC_WW_Pin1_4 482 487 PF00397 0.632
DOC_WW_Pin1_4 53 58 PF00397 0.541
DOC_WW_Pin1_4 559 564 PF00397 0.672
DOC_WW_Pin1_4 66 71 PF00397 0.691
DOC_WW_Pin1_4 79 84 PF00397 0.596
LIG_14-3-3_CanoR_1 127 136 PF00244 0.630
LIG_14-3-3_CanoR_1 187 191 PF00244 0.514
LIG_14-3-3_CanoR_1 243 251 PF00244 0.660
LIG_14-3-3_CanoR_1 319 327 PF00244 0.592
LIG_Actin_WH2_2 172 189 PF00022 0.467
LIG_BRCT_BRCA1_1 260 264 PF00533 0.604
LIG_BRCT_BRCA1_1 649 653 PF00533 0.628
LIG_Clathr_ClatBox_1 170 174 PF01394 0.451
LIG_Clathr_ClatBox_1 5 9 PF01394 0.623
LIG_FHA_1 187 193 PF00498 0.495
LIG_FHA_1 339 345 PF00498 0.438
LIG_FHA_1 35 41 PF00498 0.847
LIG_FHA_1 388 394 PF00498 0.595
LIG_FHA_1 516 522 PF00498 0.664
LIG_FHA_1 531 537 PF00498 0.562
LIG_FHA_2 111 117 PF00498 0.735
LIG_FHA_2 120 126 PF00498 0.524
LIG_FHA_2 199 205 PF00498 0.507
LIG_FHA_2 294 300 PF00498 0.502
LIG_FHA_2 362 368 PF00498 0.502
LIG_LIR_Apic_2 20 24 PF02991 0.572
LIG_LIR_Apic_2 234 240 PF02991 0.598
LIG_LIR_Apic_2 650 656 PF02991 0.618
LIG_LIR_Gen_1 400 407 PF02991 0.514
LIG_LIR_Gen_1 634 641 PF02991 0.749
LIG_LIR_Gen_1 643 654 PF02991 0.610
LIG_LIR_Nem_3 375 379 PF02991 0.482
LIG_LIR_Nem_3 400 406 PF02991 0.636
LIG_LIR_Nem_3 585 591 PF02991 0.675
LIG_LIR_Nem_3 634 638 PF02991 0.754
LIG_LIR_Nem_3 643 649 PF02991 0.607
LIG_LIR_Nem_3 650 654 PF02991 0.523
LIG_LYPXL_yS_3 543 546 PF13949 0.674
LIG_LYPXL_yS_3 651 654 PF13949 0.674
LIG_MAD2 243 251 PF02301 0.601
LIG_PCNA_yPIPBox_3 307 318 PF02747 0.426
LIG_Pex14_2 173 177 PF04695 0.472
LIG_RPA_C_Fungi 302 314 PF08784 0.489
LIG_SH2_CRK 403 407 PF00017 0.514
LIG_SH2_CRK 646 650 PF00017 0.672
LIG_SH2_NCK_1 403 407 PF00017 0.514
LIG_SH2_NCK_1 497 501 PF00017 0.686
LIG_SH2_PTP2 483 486 PF00017 0.539
LIG_SH2_STAP1 403 407 PF00017 0.514
LIG_SH2_STAT3 504 507 PF00017 0.688
LIG_SH2_STAT3 58 61 PF00017 0.711
LIG_SH2_STAT5 200 203 PF00017 0.467
LIG_SH2_STAT5 304 307 PF00017 0.509
LIG_SH2_STAT5 343 346 PF00017 0.597
LIG_SH2_STAT5 465 468 PF00017 0.690
LIG_SH2_STAT5 483 486 PF00017 0.589
LIG_SH2_STAT5 497 500 PF00017 0.611
LIG_SH2_STAT5 504 507 PF00017 0.688
LIG_SH2_STAT5 590 593 PF00017 0.692
LIG_SH3_1 483 489 PF00018 0.538
LIG_SH3_2 563 568 PF14604 0.613
LIG_SH3_3 101 107 PF00018 0.703
LIG_SH3_3 130 136 PF00018 0.674
LIG_SH3_3 428 434 PF00018 0.667
LIG_SH3_3 483 489 PF00018 0.601
LIG_SH3_3 500 506 PF00018 0.672
LIG_SH3_3 538 544 PF00018 0.686
LIG_SH3_3 557 563 PF00018 0.509
LIG_SH3_3 580 586 PF00018 0.627
LIG_SH3_3 627 633 PF00018 0.657
LIG_SH3_3 646 652 PF00018 0.502
LIG_SUMO_SIM_anti_2 535 540 PF11976 0.644
LIG_SUMO_SIM_par_1 168 174 PF11976 0.541
LIG_SUMO_SIM_par_1 2 9 PF11976 0.700
LIG_SUMO_SIM_par_1 33 44 PF11976 0.588
LIG_SUMO_SIM_par_1 517 523 PF11976 0.668
LIG_TRAF2_1 113 116 PF00917 0.681
LIG_TRFH_1 497 501 PF08558 0.686
LIG_TYR_ITIM 401 406 PF00017 0.629
LIG_TYR_ITIM 541 546 PF00017 0.678
LIG_TYR_ITIM 649 654 PF00017 0.675
LIG_TYR_ITSM 585 592 PF00017 0.549
MOD_CDC14_SPxK_1 163 166 PF00782 0.462
MOD_CDC14_SPxK_1 82 85 PF00782 0.701
MOD_CDK_SPxK_1 160 166 PF00069 0.512
MOD_CDK_SPxK_1 79 85 PF00069 0.712
MOD_CDK_SPxxK_3 485 492 PF00069 0.532
MOD_CK1_1 226 232 PF00069 0.607
MOD_CK1_1 457 463 PF00069 0.673
MOD_CK1_1 56 62 PF00069 0.550
MOD_CK1_1 645 651 PF00069 0.622
MOD_CK1_1 657 663 PF00069 0.561
MOD_CK1_1 97 103 PF00069 0.703
MOD_CK2_1 110 116 PF00069 0.738
MOD_CK2_1 198 204 PF00069 0.507
MOD_CK2_1 251 257 PF00069 0.620
MOD_CK2_1 36 42 PF00069 0.593
MOD_GlcNHglycan 108 111 PF01048 0.656
MOD_GlcNHglycan 115 120 PF01048 0.589
MOD_GlcNHglycan 122 125 PF01048 0.667
MOD_GlcNHglycan 260 263 PF01048 0.629
MOD_GlcNHglycan 276 279 PF01048 0.447
MOD_GlcNHglycan 329 332 PF01048 0.462
MOD_GlcNHglycan 353 356 PF01048 0.501
MOD_GlcNHglycan 413 416 PF01048 0.599
MOD_GlcNHglycan 473 476 PF01048 0.685
MOD_GlcNHglycan 580 583 PF01048 0.647
MOD_GlcNHglycan 593 596 PF01048 0.585
MOD_GlcNHglycan 609 612 PF01048 0.610
MOD_GlcNHglycan 96 99 PF01048 0.787
MOD_GSK3_1 106 113 PF00069 0.691
MOD_GSK3_1 115 122 PF00069 0.684
MOD_GSK3_1 143 150 PF00069 0.672
MOD_GSK3_1 247 254 PF00069 0.673
MOD_GSK3_1 265 272 PF00069 0.445
MOD_GSK3_1 32 39 PF00069 0.770
MOD_GSK3_1 387 394 PF00069 0.604
MOD_GSK3_1 456 463 PF00069 0.631
MOD_GSK3_1 511 518 PF00069 0.787
MOD_GSK3_1 520 527 PF00069 0.691
MOD_GSK3_1 530 537 PF00069 0.530
MOD_GSK3_1 574 581 PF00069 0.611
MOD_GSK3_1 654 661 PF00069 0.584
MOD_GSK3_1 92 99 PF00069 0.659
MOD_LATS_1 409 415 PF00433 0.579
MOD_N-GLC_1 40 45 PF02516 0.705
MOD_N-GLC_1 558 563 PF02516 0.647
MOD_N-GLC_1 657 662 PF02516 0.549
MOD_NEK2_1 1 6 PF00069 0.775
MOD_NEK2_1 186 191 PF00069 0.542
MOD_NEK2_1 19 24 PF00069 0.635
MOD_NEK2_1 264 269 PF00069 0.645
MOD_NEK2_1 361 366 PF00069 0.595
MOD_NEK2_1 387 392 PF00069 0.642
MOD_NEK2_1 40 45 PF00069 0.663
MOD_NEK2_1 454 459 PF00069 0.542
MOD_NEK2_1 495 500 PF00069 0.623
MOD_NEK2_1 619 624 PF00069 0.539
MOD_NEK2_2 338 343 PF00069 0.392
MOD_PIKK_1 346 352 PF00454 0.531
MOD_PIKK_1 438 444 PF00454 0.700
MOD_PIKK_1 454 460 PF00454 0.524
MOD_PIKK_1 520 526 PF00454 0.620
MOD_PIKK_1 530 536 PF00454 0.615
MOD_PIKK_1 544 550 PF00454 0.559
MOD_PIKK_1 56 62 PF00454 0.533
MOD_PKA_1 293 299 PF00069 0.501
MOD_PKA_1 411 417 PF00069 0.579
MOD_PKA_2 186 192 PF00069 0.488
MOD_PKA_2 293 299 PF00069 0.501
MOD_PKA_2 411 417 PF00069 0.579
MOD_Plk_1 1 7 PF00069 0.805
MOD_Plk_1 211 217 PF00069 0.496
MOD_Plk_1 32 38 PF00069 0.655
MOD_Plk_1 657 663 PF00069 0.489
MOD_Plk_4 1 7 PF00069 0.723
MOD_Plk_4 205 211 PF00069 0.456
MOD_Plk_4 212 218 PF00069 0.436
MOD_Plk_4 251 257 PF00069 0.620
MOD_Plk_4 322 328 PF00069 0.513
MOD_Plk_4 338 344 PF00069 0.432
MOD_Plk_4 361 367 PF00069 0.497
MOD_Plk_4 457 463 PF00069 0.628
MOD_Plk_4 466 472 PF00069 0.655
MOD_Plk_4 534 540 PF00069 0.695
MOD_Plk_4 584 590 PF00069 0.545
MOD_Plk_4 631 637 PF00069 0.542
MOD_ProDKin_1 149 155 PF00069 0.670
MOD_ProDKin_1 160 166 PF00069 0.539
MOD_ProDKin_1 235 241 PF00069 0.683
MOD_ProDKin_1 247 253 PF00069 0.629
MOD_ProDKin_1 476 482 PF00069 0.671
MOD_ProDKin_1 485 491 PF00069 0.610
MOD_ProDKin_1 53 59 PF00069 0.541
MOD_ProDKin_1 559 565 PF00069 0.672
MOD_ProDKin_1 66 72 PF00069 0.693
MOD_ProDKin_1 79 85 PF00069 0.594
TRG_ENDOCYTIC_2 403 406 PF00928 0.635
TRG_ENDOCYTIC_2 543 546 PF00928 0.674
TRG_ENDOCYTIC_2 588 591 PF00928 0.687
TRG_ENDOCYTIC_2 646 649 PF00928 0.699
TRG_ENDOCYTIC_2 651 654 PF00928 0.637
TRG_ER_diArg_1 284 287 PF00400 0.587
TRG_ER_diArg_1 292 294 PF00400 0.442
TRG_NES_CRM1_1 388 400 PF08389 0.437
TRG_Pf-PMV_PEXEL_1 319 324 PF00026 0.636

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IJZ7 Leishmania donovani 89% 99%
A4HQ65 Leishmania braziliensis 70% 98%
A4IDW2 Leishmania infantum 88% 100%
Q4Q0L3 Leishmania major 87% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS