LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ATT2_LEIMU
TriTrypDb:
LmxM.36.4980
Length:
334

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATT2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATT2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 120 124 PF00656 0.620
CLV_MEL_PAP_1 174 180 PF00089 0.554
CLV_NRD_NRD_1 259 261 PF00675 0.593
CLV_NRD_NRD_1 269 271 PF00675 0.596
CLV_NRD_NRD_1 70 72 PF00675 0.760
CLV_NRD_NRD_1 74 76 PF00675 0.701
CLV_PCSK_KEX2_1 259 261 PF00082 0.584
CLV_PCSK_KEX2_1 70 72 PF00082 0.816
CLV_PCSK_KEX2_1 74 76 PF00082 0.796
CLV_PCSK_PC7_1 70 76 PF00082 0.765
CLV_PCSK_SKI1_1 10 14 PF00082 0.498
CLV_PCSK_SKI1_1 130 134 PF00082 0.801
CLV_PCSK_SKI1_1 188 192 PF00082 0.585
CLV_PCSK_SKI1_1 217 221 PF00082 0.584
DEG_APCC_DBOX_1 259 267 PF00400 0.544
DEG_Nend_UBRbox_2 1 3 PF02207 0.691
DEG_SPOP_SBC_1 327 331 PF00917 0.457
DOC_CDC14_PxL_1 237 245 PF14671 0.628
DOC_MAPK_FxFP_2 324 327 PF00069 0.560
DOC_PP1_RVXF_1 215 222 PF00149 0.588
DOC_PP4_FxxP_1 13 16 PF00568 0.498
DOC_PP4_FxxP_1 183 186 PF00568 0.555
DOC_PP4_FxxP_1 324 327 PF00568 0.560
DOC_USP7_MATH_1 108 112 PF00917 0.814
DOC_USP7_MATH_1 149 153 PF00917 0.716
DOC_USP7_MATH_1 164 168 PF00917 0.613
DOC_USP7_MATH_1 327 331 PF00917 0.600
DOC_USP7_MATH_1 45 49 PF00917 0.591
DOC_USP7_MATH_1 8 12 PF00917 0.493
DOC_USP7_UBL2_3 81 85 PF12436 0.773
DOC_WW_Pin1_4 230 235 PF00397 0.593
DOC_WW_Pin1_4 60 65 PF00397 0.802
LIG_14-3-3_CanoR_1 170 175 PF00244 0.524
LIG_14-3-3_CanoR_1 44 52 PF00244 0.415
LIG_BRCT_BRCA1_1 172 176 PF00533 0.519
LIG_BRCT_BRCA1_1 179 183 PF00533 0.540
LIG_FHA_1 293 299 PF00498 0.495
LIG_FHA_1 323 329 PF00498 0.577
LIG_FHA_2 118 124 PF00498 0.715
LIG_FHA_2 252 258 PF00498 0.662
LIG_GBD_Chelix_1 306 314 PF00786 0.510
LIG_IBAR_NPY_1 30 32 PF08397 0.651
LIG_LIR_Apic_2 11 16 PF02991 0.495
LIG_LIR_Apic_2 180 186 PF02991 0.546
LIG_LIR_Apic_2 228 234 PF02991 0.609
LIG_LIR_Apic_2 321 327 PF02991 0.552
LIG_LIR_Nem_3 46 52 PF02991 0.561
LIG_Pex14_2 178 182 PF04695 0.553
LIG_Pex14_2 183 187 PF04695 0.566
LIG_SH2_CRK 171 175 PF00017 0.519
LIG_SH2_CRK 53 57 PF00017 0.614
LIG_SH2_NCK_1 171 175 PF00017 0.519
LIG_SH2_SRC 51 54 PF00017 0.709
LIG_SH2_STAP1 32 36 PF00017 0.647
LIG_SH2_STAT5 222 225 PF00017 0.641
LIG_SH2_STAT5 231 234 PF00017 0.553
LIG_SH2_STAT5 51 54 PF00017 0.709
LIG_SH3_1 61 67 PF00018 0.746
LIG_SH3_3 194 200 PF00018 0.586
LIG_SH3_3 61 67 PF00018 0.746
LIG_SUMO_SIM_par_1 286 292 PF11976 0.519
LIG_TRAF2_1 233 236 PF00917 0.611
LIG_TRAF2_1 315 318 PF00917 0.496
LIG_TRAF2_2 279 284 PF00917 0.526
LIG_TYR_ITIM 169 174 PF00017 0.529
LIG_WRC_WIRS_1 187 192 PF05994 0.582
MOD_CK1_1 118 124 PF00069 0.763
MOD_CK1_1 141 147 PF00069 0.804
MOD_CK1_1 152 158 PF00069 0.614
MOD_CK1_1 211 217 PF00069 0.570
MOD_CK1_1 292 298 PF00069 0.476
MOD_CK1_1 54 60 PF00069 0.744
MOD_CK2_1 230 236 PF00069 0.585
MOD_GlcNHglycan 10 13 PF01048 0.670
MOD_GlcNHglycan 104 107 PF01048 0.699
MOD_GlcNHglycan 123 126 PF01048 0.756
MOD_GlcNHglycan 152 155 PF01048 0.703
MOD_GlcNHglycan 179 182 PF01048 0.541
MOD_GlcNHglycan 210 213 PF01048 0.661
MOD_GlcNHglycan 22 25 PF01048 0.639
MOD_GlcNHglycan 290 294 PF01048 0.492
MOD_GSK3_1 115 122 PF00069 0.705
MOD_GSK3_1 138 145 PF00069 0.709
MOD_GSK3_1 152 159 PF00069 0.703
MOD_GSK3_1 18 25 PF00069 0.516
MOD_GSK3_1 2 9 PF00069 0.684
MOD_GSK3_1 208 215 PF00069 0.502
MOD_GSK3_1 322 329 PF00069 0.509
MOD_GSK3_1 81 88 PF00069 0.737
MOD_GSK3_1 98 105 PF00069 0.520
MOD_N-GLC_1 201 206 PF02516 0.594
MOD_NEK2_1 140 145 PF00069 0.691
MOD_NEK2_1 22 27 PF00069 0.478
MOD_NEK2_1 289 294 PF00069 0.521
MOD_NEK2_1 301 306 PF00069 0.526
MOD_NEK2_1 4 9 PF00069 0.611
MOD_NEK2_1 98 103 PF00069 0.691
MOD_NEK2_2 201 206 PF00069 0.594
MOD_NEK2_2 86 91 PF00069 0.743
MOD_PIKK_1 142 148 PF00454 0.738
MOD_PK_1 170 176 PF00069 0.523
MOD_PKA_2 43 49 PF00069 0.413
MOD_Plk_1 201 207 PF00069 0.551
MOD_Plk_1 261 267 PF00069 0.615
MOD_Plk_1 289 295 PF00069 0.485
MOD_Plk_1 98 104 PF00069 0.521
MOD_Plk_4 164 170 PF00069 0.610
MOD_Plk_4 292 298 PF00069 0.440
MOD_Plk_4 51 57 PF00069 0.716
MOD_ProDKin_1 230 236 PF00069 0.592
MOD_ProDKin_1 60 66 PF00069 0.804
MOD_SUMO_rev_2 249 256 PF00179 0.578
TRG_DiLeu_BaLyEn_6 239 244 PF01217 0.636
TRG_ENDOCYTIC_2 171 174 PF00928 0.508
TRG_ENDOCYTIC_2 53 56 PF00928 0.550
TRG_ER_diArg_1 258 260 PF00400 0.563
TRG_NLS_MonoExtC_3 70 75 PF00514 0.757
TRG_NLS_MonoExtN_4 70 75 PF00514 0.731
TRG_Pf-PMV_PEXEL_1 270 275 PF00026 0.528

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PBG8 Leptomonas seymouri 60% 100%
A0A3Q8IJQ3 Leishmania donovani 90% 100%
A4HQ15 Leishmania braziliensis 73% 99%
A4IDS1 Leishmania infantum 90% 100%
Q4Q0R4 Leishmania major 92% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS