J domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9ATT1_LEIMU

TriTrypDb:

LmxM.36.4970

Length:

348

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATT1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATT1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	110	112	PF00675	0.579
CLV_NRD_NRD_1	118	120	PF00675	0.502
CLV_NRD_NRD_1	203	205	PF00675	0.389
CLV_NRD_NRD_1	222	224	PF00675	0.438
CLV_NRD_NRD_1	253	255	PF00675	0.699
CLV_NRD_NRD_1	257	259	PF00675	0.695
CLV_NRD_NRD_1	277	279	PF00675	0.543
CLV_NRD_NRD_1	43	45	PF00675	0.563
CLV_PCSK_FUR_1	115	119	PF00082	0.539
CLV_PCSK_KEX2_1	115	117	PF00082	0.546
CLV_PCSK_KEX2_1	118	120	PF00082	0.532
CLV_PCSK_KEX2_1	203	205	PF00082	0.389
CLV_PCSK_KEX2_1	222	224	PF00082	0.438
CLV_PCSK_KEX2_1	253	255	PF00082	0.652
CLV_PCSK_KEX2_1	257	259	PF00082	0.650
CLV_PCSK_KEX2_1	279	281	PF00082	0.580
CLV_PCSK_KEX2_1	342	344	PF00082	0.590
CLV_PCSK_KEX2_1	43	45	PF00082	0.562
CLV_PCSK_PC1ET2_1	222	224	PF00082	0.457
CLV_PCSK_PC1ET2_1	279	281	PF00082	0.662
CLV_PCSK_PC1ET2_1	342	344	PF00082	0.590
CLV_PCSK_PC7_1	111	117	PF00082	0.435
CLV_PCSK_PC7_1	253	259	PF00082	0.673
CLV_PCSK_SKI1_1	167	171	PF00082	0.500
CLV_PCSK_SKI1_1	196	200	PF00082	0.481
CLV_PCSK_SKI1_1	253	257	PF00082	0.691
CLV_PCSK_SKI1_1	4	8	PF00082	0.466
DEG_Nend_Nbox_1	1	3	PF02207	0.521
DOC_CKS1_1	273	278	PF01111	0.444
DOC_CYCLIN_RxL_1	18	26	PF00134	0.335
DOC_CYCLIN_yCln2_LP_2	194	200	PF00134	0.485
DOC_MAPK_gen_1	290	300	PF00069	0.614
DOC_PP4_FxxP_1	273	276	PF00568	0.521
DOC_USP7_MATH_1	233	237	PF00917	0.673
DOC_USP7_MATH_1	32	36	PF00917	0.599
DOC_WW_Pin1_4	242	247	PF00397	0.686
DOC_WW_Pin1_4	256	261	PF00397	0.739
DOC_WW_Pin1_4	272	277	PF00397	0.590
DOC_WW_Pin1_4	310	315	PF00397	0.682
DOC_WW_Pin1_4	323	328	PF00397	0.731
LIG_14-3-3_CanoR_1	182	188	PF00244	0.425
LIG_14-3-3_CanoR_1	223	230	PF00244	0.399
LIG_14-3-3_CanoR_1	30	39	PF00244	0.559
LIG_BRCT_BRCA1_1	165	169	PF00533	0.480
LIG_deltaCOP1_diTrp_1	281	289	PF00928	0.607
LIG_FHA_1	145	151	PF00498	0.564
LIG_FHA_2	134	140	PF00498	0.604
LIG_FHA_2	147	153	PF00498	0.680
LIG_FHA_2	168	174	PF00498	0.440
LIG_FHA_2	197	203	PF00498	0.405
LIG_FHA_2	297	303	PF00498	0.511
LIG_FHA_2	68	74	PF00498	0.369
LIG_LIR_Apic_2	288	292	PF02991	0.657
LIG_LIR_Gen_1	137	144	PF02991	0.509
LIG_LIR_Gen_1	70	80	PF02991	0.406
LIG_LIR_Nem_3	137	143	PF02991	0.527
LIG_LIR_Nem_3	166	171	PF02991	0.454
LIG_LIR_Nem_3	176	181	PF02991	0.427
LIG_LIR_Nem_3	337	341	PF02991	0.512
LIG_LIR_Nem_3	70	75	PF02991	0.374
LIG_MAD2	21	29	PF02301	0.516
LIG_MLH1_MIPbox_1	165	169	PF16413	0.466
LIG_NRBOX	305	311	PF00104	0.625
LIG_PCNA_yPIPBox_3	303	315	PF02747	0.633
LIG_PDZ_Class_1	343	348	PF00595	0.446
LIG_Pex14_1	282	286	PF04695	0.662
LIG_PTB_Apo_2	204	211	PF02174	0.392
LIG_PTB_Apo_2	66	73	PF02174	0.379
LIG_PTB_Phospho_1	66	72	PF10480	0.376
LIG_SH2_CRK	178	182	PF00017	0.423
LIG_SH2_CRK	341	345	PF00017	0.564
LIG_SH2_GRB2like	338	341	PF00017	0.491
LIG_SH2_NCK_1	72	76	PF00017	0.498
LIG_SH2_SRC	261	264	PF00017	0.578
LIG_SH2_STAP1	85	89	PF00017	0.428
LIG_SH2_STAT3	294	297	PF00017	0.611
LIG_SH2_STAT5	216	219	PF00017	0.389
LIG_SH2_STAT5	46	49	PF00017	0.389
LIG_SH3_3	26	32	PF00018	0.500
LIG_SH3_3	281	287	PF00018	0.568
LIG_SH3_3	321	327	PF00018	0.636
LIG_TRAF2_1	151	154	PF00917	0.523
LIG_TRAF2_1	299	302	PF00917	0.462
LIG_TYR_ITSM	174	181	PF00017	0.437
LIG_TYR_ITSM	68	75	PF00017	0.495
LIG_WRC_WIRS_1	168	173	PF05994	0.395
MOD_CDK_SPK_2	310	315	PF00069	0.682
MOD_CDK_SPxK_1	272	278	PF00069	0.633
MOD_CDK_SPxxK_3	272	279	PF00069	0.635
MOD_CK1_1	130	136	PF00069	0.501
MOD_CK1_1	146	152	PF00069	0.527
MOD_CK1_1	235	241	PF00069	0.692
MOD_CK1_1	326	332	PF00069	0.700
MOD_CK2_1	146	152	PF00069	0.581
MOD_CK2_1	196	202	PF00069	0.398
MOD_CK2_1	256	262	PF00069	0.641
MOD_CK2_1	282	288	PF00069	0.640
MOD_CK2_1	296	302	PF00069	0.474
MOD_CK2_1	67	73	PF00069	0.375
MOD_Cter_Amidation	113	116	PF01082	0.500
MOD_GlcNHglycan	125	128	PF01048	0.674
MOD_GlcNHglycan	235	238	PF01048	0.624
MOD_GlcNHglycan	328	331	PF01048	0.707
MOD_GlcNHglycan	58	61	PF01048	0.469
MOD_GlcNHglycan	77	80	PF01048	0.556
MOD_GlcNHglycan	86	90	PF01048	0.564
MOD_GSK3_1	123	130	PF00069	0.598
MOD_GSK3_1	144	151	PF00069	0.587
MOD_GSK3_1	163	170	PF00069	0.498
MOD_GSK3_1	222	229	PF00069	0.559
MOD_GSK3_1	235	242	PF00069	0.655
MOD_GSK3_1	245	252	PF00069	0.621
MOD_GSK3_1	322	329	PF00069	0.665
MOD_LATS_1	165	171	PF00433	0.445
MOD_N-GLC_1	144	149	PF02516	0.560
MOD_NEK2_1	163	168	PF00069	0.495
MOD_NEK2_1	2	7	PF00069	0.561
MOD_NEK2_1	23	28	PF00069	0.475
MOD_NEK2_1	239	244	PF00069	0.791
MOD_NEK2_1	74	79	PF00069	0.423
MOD_NEK2_2	183	188	PF00069	0.420
MOD_PKA_1	222	228	PF00069	0.650
MOD_PKA_2	222	228	PF00069	0.601
MOD_Plk_1	127	133	PF00069	0.652
MOD_Plk_1	173	179	PF00069	0.376
MOD_Plk_2-3	148	154	PF00069	0.629
MOD_Plk_2-3	296	302	PF00069	0.594
MOD_Plk_4	173	179	PF00069	0.376
MOD_Plk_4	196	202	PF00069	0.398
MOD_ProDKin_1	242	248	PF00069	0.686
MOD_ProDKin_1	256	262	PF00069	0.739
MOD_ProDKin_1	272	278	PF00069	0.590
MOD_ProDKin_1	310	316	PF00069	0.684
MOD_ProDKin_1	323	329	PF00069	0.729
MOD_SUMO_rev_2	148	158	PF00179	0.585
TRG_DiLeu_BaEn_4	301	307	PF01217	0.578
TRG_ENDOCYTIC_2	178	181	PF00928	0.413
TRG_ENDOCYTIC_2	341	344	PF00928	0.495
TRG_ENDOCYTIC_2	46	49	PF00928	0.429
TRG_ENDOCYTIC_2	72	75	PF00928	0.360
TRG_ER_diArg_1	115	118	PF00400	0.544
TRG_ER_diArg_1	203	205	PF00400	0.389
TRG_ER_diArg_1	256	258	PF00400	0.689
TRG_ER_diArg_1	42	44	PF00400	0.527
TRG_Pf-PMV_PEXEL_1	118	122	PF00026	0.426
TRG_PTS1	345	348	PF00515	0.588

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P554	Leptomonas seymouri	67%	93%
A0A1X0P394	Trypanosomatidae	41%	88%
A0A3Q8IRL6	Leishmania donovani	91%	100%
A0A3R7NA51	Trypanosoma rangeli	51%	98%
A4HQ14	Leishmania braziliensis	83%	100%
A4ICE4	Leishmania infantum	91%	100%
D0A8V6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
Q4Q0R5	Leishmania major	91%	99%
V5BDN3	Trypanosoma cruzi	49%	100%