PABS domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATR4_LEIMU

TriTrypDb:

LmxM.36.4800

Length:

511

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATR4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATR4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.618
CLV_NRD_NRD_1	101	103	PF00675	0.596
CLV_NRD_NRD_1	211	213	PF00675	0.407
CLV_NRD_NRD_1	23	25	PF00675	0.651
CLV_NRD_NRD_1	402	404	PF00675	0.315
CLV_PCSK_FUR_1	7	11	PF00082	0.572
CLV_PCSK_KEX2_1	10	12	PF00082	0.623
CLV_PCSK_KEX2_1	21	23	PF00082	0.643
CLV_PCSK_KEX2_1	286	288	PF00082	0.508
CLV_PCSK_KEX2_1	7	9	PF00082	0.611
CLV_PCSK_KEX2_1	78	80	PF00082	0.389
CLV_PCSK_PC1ET2_1	21	23	PF00082	0.631
CLV_PCSK_PC1ET2_1	286	288	PF00082	0.508
CLV_PCSK_PC1ET2_1	78	80	PF00082	0.389
CLV_PCSK_SKI1_1	323	327	PF00082	0.414
CLV_PCSK_SKI1_1	403	407	PF00082	0.486
CLV_PCSK_SKI1_1	52	56	PF00082	0.418
CLV_PCSK_SKI1_1	75	79	PF00082	0.416
DEG_ODPH_VHL_1	4	17	PF01847	0.618
DEG_SPOP_SBC_1	268	272	PF00917	0.645
DOC_MAPK_DCC_7	86	96	PF00069	0.368
DOC_MAPK_gen_1	403	413	PF00069	0.250
DOC_MAPK_gen_1	7	17	PF00069	0.592
DOC_MAPK_JIP1_4	407	413	PF00069	0.429
DOC_MAPK_MEF2A_6	46	53	PF00069	0.450
DOC_MAPK_NFAT4_5	46	54	PF00069	0.458
DOC_USP7_MATH_1	109	113	PF00917	0.717
DOC_USP7_MATH_1	117	121	PF00917	0.589
DOC_USP7_MATH_1	160	164	PF00917	0.486
DOC_USP7_MATH_1	228	232	PF00917	0.384
DOC_WW_Pin1_4	131	136	PF00397	0.622
DOC_WW_Pin1_4	451	456	PF00397	0.301
LIG_14-3-3_CanoR_1	110	114	PF00244	0.640
LIG_14-3-3_CanoR_1	212	217	PF00244	0.430
LIG_14-3-3_CanoR_1	22	30	PF00244	0.483
LIG_14-3-3_CanoR_1	245	254	PF00244	0.701
LIG_14-3-3_CanoR_1	276	280	PF00244	0.655
LIG_14-3-3_CanoR_1	287	294	PF00244	0.453
LIG_14-3-3_CanoR_1	443	451	PF00244	0.468
LIG_14-3-3_CanoR_1	495	500	PF00244	0.284
LIG_14-3-3_CanoR_1	64	72	PF00244	0.352
LIG_14-3-3_CanoR_1	8	17	PF00244	0.596
LIG_14-3-3_CterR_2	507	511	PF00244	0.372
LIG_Actin_WH2_2	190	206	PF00022	0.345
LIG_Actin_WH2_2	76	94	PF00022	0.367
LIG_FHA_1	10	16	PF00498	0.571
LIG_FHA_1	254	260	PF00498	0.542
LIG_FHA_1	263	269	PF00498	0.542
LIG_FHA_1	303	309	PF00498	0.446
LIG_FHA_1	400	406	PF00498	0.461
LIG_FHA_1	53	59	PF00498	0.539
LIG_FHA_1	64	70	PF00498	0.291
LIG_FHA_2	137	143	PF00498	0.648
LIG_FHA_2	163	169	PF00498	0.525
LIG_FHA_2	213	219	PF00498	0.347
LIG_FHA_2	235	241	PF00498	0.563
LIG_FHA_2	348	354	PF00498	0.423
LIG_FHA_2	452	458	PF00498	0.404
LIG_FHA_2	468	474	PF00498	0.431
LIG_FHA_2	96	102	PF00498	0.650
LIG_GBD_Chelix_1	474	482	PF00786	0.375
LIG_LIR_Apic_2	112	116	PF02991	0.667
LIG_LIR_Gen_1	194	203	PF02991	0.333
LIG_LIR_Gen_1	292	302	PF02991	0.278
LIG_LIR_Gen_1	378	388	PF02991	0.338
LIG_LIR_Nem_3	194	198	PF02991	0.333
LIG_LIR_Nem_3	292	297	PF02991	0.305
LIG_LIR_Nem_3	378	384	PF02991	0.328
LIG_LIR_Nem_3	473	479	PF02991	0.421
LIG_MYND_1	2	6	PF01753	0.623
LIG_Pex14_1	486	490	PF04695	0.331
LIG_Pex14_2	44	48	PF04695	0.431
LIG_SH2_CRK	113	117	PF00017	0.566
LIG_SH2_CRK	200	204	PF00017	0.414
LIG_SH2_CRK	377	381	PF00017	0.326
LIG_SH2_CRK	428	432	PF00017	0.441
LIG_SH2_NCK_1	428	432	PF00017	0.441
LIG_SH2_STAP1	377	381	PF00017	0.326
LIG_SH2_STAP1	428	432	PF00017	0.441
LIG_SH2_STAP1	463	467	PF00017	0.376
LIG_SH2_STAP1	479	483	PF00017	0.353
LIG_SH2_STAT5	148	151	PF00017	0.362
LIG_SH2_STAT5	200	203	PF00017	0.409
LIG_SH3_1	103	109	PF00018	0.579
LIG_SH3_2	3	8	PF14604	0.619
LIG_SH3_3	103	109	PF00018	0.539
LIG_SUMO_SIM_par_1	329	336	PF11976	0.356
LIG_TRAF2_1	215	218	PF00917	0.304
LIG_TRAF2_1	98	101	PF00917	0.602
LIG_TYR_ITIM	198	203	PF00017	0.409
LIG_WRC_WIRS_1	192	197	PF05994	0.333
LIG_WRC_WIRS_1	291	296	PF05994	0.318
LIG_WW_3	107	111	PF00397	0.669
MOD_CK1_1	141	147	PF00069	0.381
MOD_CK1_1	167	173	PF00069	0.443
MOD_CK1_1	191	197	PF00069	0.468
MOD_CK1_1	231	237	PF00069	0.677
MOD_CK1_1	289	295	PF00069	0.558
MOD_CK2_1	212	218	PF00069	0.431
MOD_CK2_1	234	240	PF00069	0.542
MOD_CK2_1	247	253	PF00069	0.532
MOD_CK2_1	95	101	PF00069	0.642
MOD_GlcNHglycan	119	122	PF01048	0.565
MOD_GlcNHglycan	162	165	PF01048	0.423
MOD_GlcNHglycan	250	253	PF01048	0.767
MOD_GlcNHglycan	260	263	PF01048	0.692
MOD_GlcNHglycan	420	423	PF01048	0.398
MOD_GSK3_1	160	167	PF00069	0.516
MOD_GSK3_1	228	235	PF00069	0.633
MOD_GSK3_1	248	255	PF00069	0.532
MOD_GSK3_1	258	265	PF00069	0.569
MOD_GSK3_1	267	274	PF00069	0.802
MOD_GSK3_1	285	292	PF00069	0.474
MOD_GSK3_1	347	354	PF00069	0.499
MOD_GSK3_1	457	464	PF00069	0.398
MOD_N-GLC_1	131	136	PF02516	0.591
MOD_N-GLC_1	246	251	PF02516	0.613
MOD_NEK2_1	17	22	PF00069	0.641
MOD_NEK2_1	38	43	PF00069	0.367
MOD_NEK2_1	388	393	PF00069	0.365
MOD_NEK2_1	465	470	PF00069	0.355
MOD_PIKK_1	262	268	PF00454	0.635
MOD_PIKK_1	269	275	PF00454	0.684
MOD_PIKK_1	63	69	PF00454	0.411
MOD_PKA_1	212	218	PF00069	0.359
MOD_PKA_1	23	29	PF00069	0.555
MOD_PKA_1	286	292	PF00069	0.467
MOD_PKA_1	9	15	PF00069	0.577
MOD_PKA_2	109	115	PF00069	0.685
MOD_PKA_2	23	29	PF00069	0.522
MOD_PKA_2	275	281	PF00069	0.655
MOD_PKA_2	286	292	PF00069	0.487
MOD_PKA_2	63	69	PF00069	0.364
MOD_PKA_2	9	15	PF00069	0.573
MOD_PKB_1	7	15	PF00069	0.594
MOD_Plk_1	141	147	PF00069	0.386
MOD_Plk_1	167	173	PF00069	0.443
MOD_Plk_1	289	295	PF00069	0.334
MOD_Plk_1	38	44	PF00069	0.371
MOD_Plk_2-3	461	467	PF00069	0.361
MOD_Plk_4	172	178	PF00069	0.384
MOD_Plk_4	188	194	PF00069	0.353
MOD_Plk_4	275	281	PF00069	0.500
MOD_Plk_4	445	451	PF00069	0.369
MOD_Plk_4	478	484	PF00069	0.434
MOD_ProDKin_1	131	137	PF00069	0.621
MOD_ProDKin_1	451	457	PF00069	0.304
MOD_SUMO_rev_2	13	17	PF00179	0.667
MOD_SUMO_rev_2	278	288	PF00179	0.608
MOD_SUMO_rev_2	353	358	PF00179	0.521
TRG_ENDOCYTIC_2	200	203	PF00928	0.409
TRG_ENDOCYTIC_2	377	380	PF00928	0.327
TRG_ENDOCYTIC_2	381	384	PF00928	0.341
TRG_ENDOCYTIC_2	428	431	PF00928	0.371
TRG_ENDOCYTIC_2	479	482	PF00928	0.352
TRG_ER_diArg_1	22	24	PF00400	0.656
TRG_ER_diArg_1	494	497	PF00400	0.377
TRG_ER_diArg_1	504	507	PF00400	0.431
TRG_ER_diArg_1	6	9	PF00400	0.597
TRG_NLS_Bipartite_1	7	25	PF00514	0.563
TRG_NLS_MonoCore_2	20	25	PF00514	0.580

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDJ0	Leptomonas seymouri	55%	100%
A0A3S7XBN4	Leishmania donovani	88%	100%
A4HPZ7	Leishmania braziliensis	78%	100%
A4IDQ8	Leishmania infantum	88%	100%
Q4Q0T3	Leishmania major	87%	100%