Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATQ5_LEIMU

TriTrypDb:

LmxM.36.4710

Length:

727

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	7
GO:0032991	protein-containing complex	1	7
GO:0043226	organelle	2	7
GO:0043228	non-membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043232	intracellular non-membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7
GO:1990904	ribonucleoprotein complex	2	7

Expansion

Sequence features

E9ATQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATQ5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	425	429	PF00656	0.392
CLV_C14_Caspase3-7	481	485	PF00656	0.479
CLV_C14_Caspase3-7	547	551	PF00656	0.657
CLV_NRD_NRD_1	223	225	PF00675	0.445
CLV_NRD_NRD_1	273	275	PF00675	0.432
CLV_NRD_NRD_1	365	367	PF00675	0.415
CLV_NRD_NRD_1	402	404	PF00675	0.581
CLV_NRD_NRD_1	475	477	PF00675	0.483
CLV_NRD_NRD_1	55	57	PF00675	0.426
CLV_NRD_NRD_1	697	699	PF00675	0.525
CLV_NRD_NRD_1	710	712	PF00675	0.402
CLV_PCSK_FUR_1	221	225	PF00082	0.477
CLV_PCSK_FUR_1	473	477	PF00082	0.446
CLV_PCSK_FUR_1	708	712	PF00082	0.527
CLV_PCSK_KEX2_1	223	225	PF00082	0.516
CLV_PCSK_KEX2_1	273	275	PF00082	0.432
CLV_PCSK_KEX2_1	365	367	PF00082	0.415
CLV_PCSK_KEX2_1	402	404	PF00082	0.567
CLV_PCSK_KEX2_1	472	474	PF00082	0.497
CLV_PCSK_KEX2_1	475	477	PF00082	0.506
CLV_PCSK_KEX2_1	545	547	PF00082	0.642
CLV_PCSK_KEX2_1	55	57	PF00082	0.502
CLV_PCSK_KEX2_1	632	634	PF00082	0.648
CLV_PCSK_KEX2_1	683	685	PF00082	0.514
CLV_PCSK_KEX2_1	697	699	PF00082	0.527
CLV_PCSK_KEX2_1	707	709	PF00082	0.557
CLV_PCSK_KEX2_1	710	712	PF00082	0.396
CLV_PCSK_PC1ET2_1	472	474	PF00082	0.515
CLV_PCSK_PC1ET2_1	545	547	PF00082	0.642
CLV_PCSK_PC1ET2_1	55	57	PF00082	0.502
CLV_PCSK_PC1ET2_1	632	634	PF00082	0.648
CLV_PCSK_PC1ET2_1	683	685	PF00082	0.514
CLV_PCSK_PC1ET2_1	707	709	PF00082	0.525
CLV_PCSK_SKI1_1	529	533	PF00082	0.549
CLV_PCSK_SKI1_1	535	539	PF00082	0.585
CLV_PCSK_SKI1_1	582	586	PF00082	0.663
CLV_PCSK_SKI1_1	627	631	PF00082	0.522
CLV_PCSK_SKI1_1	633	637	PF00082	0.505
CLV_PCSK_SKI1_1	691	695	PF00082	0.519
DEG_APCC_DBOX_1	364	372	PF00400	0.395
DEG_Nend_UBRbox_2	1	3	PF02207	0.497
DEG_SCF_TRCP1_1	614	620	PF00400	0.523
DOC_ANK_TNKS_1	474	481	PF00023	0.426
DOC_MAPK_gen_1	221	228	PF00069	0.468
DOC_MAPK_gen_1	694	703	PF00069	0.487
DOC_PP1_RVXF_1	523	529	PF00149	0.488
DOC_PP1_RVXF_1	697	704	PF00149	0.495
DOC_USP7_MATH_1	660	664	PF00917	0.674
DOC_USP7_MATH_1	666	670	PF00917	0.728
DOC_USP7_MATH_1	98	102	PF00917	0.538
DOC_USP7_UBL2_3	167	171	PF12436	0.591
DOC_USP7_UBL2_3	567	571	PF12436	0.625
DOC_USP7_UBL2_3	627	631	PF12436	0.558
DOC_WW_Pin1_4	299	304	PF00397	0.387
DOC_WW_Pin1_4	593	598	PF00397	0.636
LIG_14-3-3_CanoR_1	121	126	PF00244	0.496
LIG_14-3-3_CanoR_1	143	152	PF00244	0.584
LIG_14-3-3_CanoR_1	178	186	PF00244	0.474
LIG_14-3-3_CanoR_1	412	422	PF00244	0.416
LIG_14-3-3_CanoR_1	455	461	PF00244	0.505
LIG_14-3-3_CanoR_1	56	60	PF00244	0.441
LIG_14-3-3_CanoR_1	589	595	PF00244	0.586
LIG_Actin_WH2_2	119	134	PF00022	0.537
LIG_APCC_ABBA_1	226	231	PF00400	0.447
LIG_BRCT_BRCA1_1	103	107	PF00533	0.475
LIG_BRCT_BRCA1_1	72	76	PF00533	0.516
LIG_FHA_1	120	126	PF00498	0.512
LIG_FHA_1	13	19	PF00498	0.592
LIG_FHA_1	42	48	PF00498	0.418
LIG_FHA_1	649	655	PF00498	0.551
LIG_FHA_2	206	212	PF00498	0.383
LIG_FHA_2	457	463	PF00498	0.467
LIG_FHA_2	512	518	PF00498	0.617
LIG_FHA_2	545	551	PF00498	0.562
LIG_LIR_Apic_2	314	318	PF02991	0.409
LIG_LIR_Gen_1	432	439	PF02991	0.394
LIG_LIR_Nem_3	432	436	PF02991	0.385
LIG_MAD2	589	597	PF02301	0.532
LIG_Pex14_1	315	319	PF04695	0.409
LIG_PTB_Apo_2	288	295	PF02174	0.490
LIG_SH2_NCK_1	378	382	PF00017	0.393
LIG_SH2_STAP1	260	264	PF00017	0.435
LIG_SH2_STAT3	235	238	PF00017	0.368
LIG_SH2_STAT3	89	92	PF00017	0.532
LIG_SH2_STAT5	113	116	PF00017	0.475
LIG_SH2_STAT5	235	238	PF00017	0.392
LIG_SH2_STAT5	241	244	PF00017	0.455
LIG_SH2_STAT5	376	379	PF00017	0.531
LIG_SH2_STAT5	399	402	PF00017	0.544
LIG_SH3_2	187	192	PF14604	0.433
LIG_SH3_3	15	21	PF00018	0.669
LIG_SH3_3	184	190	PF00018	0.482
LIG_SH3_3	34	40	PF00018	0.269
LIG_SH3_3	575	581	PF00018	0.530
LIG_SH3_3	591	597	PF00018	0.540
LIG_SH3_3	60	66	PF00018	0.549
LIG_SUMO_SIM_anti_2	122	127	PF11976	0.475
LIG_SUMO_SIM_par_1	120	127	PF11976	0.526
LIG_SUMO_SIM_par_1	210	219	PF11976	0.405
LIG_SUMO_SIM_par_1	420	425	PF11976	0.385
LIG_TRAF2_1	138	141	PF00917	0.493
LIG_WRC_WIRS_1	332	337	PF05994	0.415
MOD_CK1_1	101	107	PF00069	0.530
MOD_CK1_1	162	168	PF00069	0.646
MOD_CK1_1	181	187	PF00069	0.502
MOD_CK1_1	252	258	PF00069	0.369
MOD_CK1_1	287	293	PF00069	0.487
MOD_CK1_1	379	385	PF00069	0.562
MOD_CK1_1	496	502	PF00069	0.814
MOD_CK1_1	505	511	PF00069	0.693
MOD_CK1_1	549	555	PF00069	0.604
MOD_CK1_1	593	599	PF00069	0.616
MOD_CK1_1	640	646	PF00069	0.703
MOD_CK1_1	669	675	PF00069	0.669
MOD_CK2_1	100	106	PF00069	0.475
MOD_CK2_1	482	488	PF00069	0.571
MOD_CK2_1	511	517	PF00069	0.613
MOD_CK2_1	55	61	PF00069	0.440
MOD_CK2_1	659	665	PF00069	0.673
MOD_Cter_Amidation	147	150	PF01082	0.679
MOD_Cter_Amidation	169	172	PF01082	0.542
MOD_GlcNHglycan	115	118	PF01048	0.343
MOD_GlcNHglycan	160	164	PF01048	0.628
MOD_GlcNHglycan	251	254	PF01048	0.361
MOD_GlcNHglycan	26	29	PF01048	0.399
MOD_GlcNHglycan	286	289	PF01048	0.472
MOD_GlcNHglycan	371	374	PF01048	0.413
MOD_GlcNHglycan	389	392	PF01048	0.752
MOD_GlcNHglycan	424	427	PF01048	0.388
MOD_GlcNHglycan	479	483	PF01048	0.466
MOD_GlcNHglycan	501	504	PF01048	0.652
MOD_GlcNHglycan	614	617	PF01048	0.700
MOD_GlcNHglycan	638	642	PF01048	0.681
MOD_GlcNHglycan	76	79	PF01048	0.563
MOD_GlcNHglycan	98	101	PF01048	0.284
MOD_GSK3_1	115	122	PF00069	0.577
MOD_GSK3_1	12	19	PF00069	0.534
MOD_GSK3_1	162	169	PF00069	0.650
MOD_GSK3_1	173	180	PF00069	0.619
MOD_GSK3_1	248	255	PF00069	0.356
MOD_GSK3_1	283	290	PF00069	0.429
MOD_GSK3_1	41	48	PF00069	0.265
MOD_GSK3_1	478	485	PF00069	0.496
MOD_GSK3_1	493	500	PF00069	0.664
MOD_GSK3_1	505	512	PF00069	0.665
MOD_GSK3_1	544	551	PF00069	0.595
MOD_GSK3_1	636	643	PF00069	0.658
MOD_GSK3_1	655	662	PF00069	0.637
MOD_GSK3_1	70	77	PF00069	0.594
MOD_GSK3_1	96	103	PF00069	0.339
MOD_N-GLC_1	284	289	PF02516	0.433
MOD_N-GLC_1	290	295	PF02516	0.490
MOD_N-GLC_1	338	343	PF02516	0.539
MOD_N-GLC_1	701	706	PF02516	0.519
MOD_N-GLC_2	199	201	PF02516	0.370
MOD_N-GLC_2	367	369	PF02516	0.382
MOD_NEK2_1	248	253	PF00069	0.349
MOD_NEK2_1	283	288	PF00069	0.408
MOD_NEK2_1	346	351	PF00069	0.364
MOD_NEK2_1	422	427	PF00069	0.383
MOD_NEK2_1	617	622	PF00069	0.595
MOD_NEK2_1	636	641	PF00069	0.615
MOD_NEK2_2	331	336	PF00069	0.479
MOD_PIKK_1	234	240	PF00454	0.381
MOD_PIKK_1	503	509	PF00454	0.606
MOD_PIKK_1	622	628	PF00454	0.515
MOD_PK_1	121	127	PF00069	0.475
MOD_PK_1	178	184	PF00069	0.482
MOD_PK_1	268	274	PF00069	0.409
MOD_PK_1	55	61	PF00069	0.516
MOD_PKA_1	544	550	PF00069	0.639
MOD_PKA_1	55	61	PF00069	0.516
MOD_PKA_1	566	572	PF00069	0.670
MOD_PKA_1	607	613	PF00069	0.534
MOD_PKA_2	177	183	PF00069	0.666
MOD_PKA_2	413	419	PF00069	0.401
MOD_PKA_2	55	61	PF00069	0.440
MOD_Plk_1	119	125	PF00069	0.475
MOD_Plk_1	16	22	PF00069	0.464
MOD_Plk_1	268	274	PF00069	0.409
MOD_Plk_1	290	296	PF00069	0.478
MOD_Plk_1	337	343	PF00069	0.478
MOD_Plk_1	374	380	PF00069	0.448
MOD_Plk_1	69	75	PF00069	0.503
MOD_Plk_1	701	707	PF00069	0.517
MOD_Plk_2-3	511	517	PF00069	0.802
MOD_Plk_2-3	550	556	PF00069	0.672
MOD_Plk_4	181	187	PF00069	0.635
MOD_Plk_4	290	296	PF00069	0.478
MOD_Plk_4	379	385	PF00069	0.508
MOD_Plk_4	70	76	PF00069	0.513
MOD_ProDKin_1	299	305	PF00069	0.387
MOD_ProDKin_1	593	599	PF00069	0.633
MOD_SUMO_for_1	693	696	PF00179	0.474
TRG_ENDOCYTIC_2	319	322	PF00928	0.406
TRG_ER_diArg_1	142	145	PF00400	0.507
TRG_ER_diArg_1	223	225	PF00400	0.478
TRG_ER_diArg_1	272	274	PF00400	0.545
TRG_ER_diArg_1	364	366	PF00400	0.430
TRG_ER_diArg_1	401	403	PF00400	0.563
TRG_ER_diArg_1	412	415	PF00400	0.454
TRG_ER_diArg_1	448	451	PF00400	0.443
TRG_ER_diArg_1	475	477	PF00400	0.483
TRG_ER_diArg_1	708	711	PF00400	0.534
TRG_NES_CRM1_1	2	14	PF08389	0.517
TRG_NLS_Bipartite_1	682	702	PF00514	0.496
TRG_NLS_MonoCore_2	629	634	PF00514	0.600
TRG_NLS_MonoExtC_3	54	60	PF00514	0.456
TRG_NLS_MonoExtN_4	627	634	PF00514	0.616
TRG_NLS_MonoExtN_4	697	702	PF00514	0.492
TRG_Pf-PMV_PEXEL_1	366	370	PF00026	0.383
TRG_Pf-PMV_PEXEL_1	458	462	PF00026	0.467
TRG_Pf-PMV_PEXEL_1	465	469	PF00026	0.465
TRG_Pf-PMV_PEXEL_1	475	479	PF00026	0.523
TRG_Pf-PMV_PEXEL_1	691	695	PF00026	0.519

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I9Z8	Leptomonas seymouri	77%	100%
A0A3S7XBM3	Leishmania donovani	88%	100%
A4HPY8	Leishmania braziliensis	75%	99%
A4IDP9	Leishmania infantum	88%	100%
Q4Q0U2	Leishmania major	88%	100%