LeishMANIAdb
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TMF_TATA_bd domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
TMF_TATA_bd domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ATQ1_LEIMU
TriTrypDb:
LmxM.36.4670
Length:
127

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9ATQ1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATQ1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 89 91 PF00675 0.412
CLV_PCSK_FUR_1 87 91 PF00082 0.375
CLV_PCSK_KEX2_1 36 38 PF00082 0.439
CLV_PCSK_KEX2_1 89 91 PF00082 0.511
CLV_PCSK_PC1ET2_1 36 38 PF00082 0.498
CLV_PCSK_SKI1_1 112 116 PF00082 0.447
CLV_PCSK_SKI1_1 36 40 PF00082 0.494
CLV_PCSK_SKI1_1 70 74 PF00082 0.400
DEG_APCC_DBOX_1 69 77 PF00400 0.414
DEG_Nend_Nbox_1 1 3 PF02207 0.595
DOC_CYCLIN_RxL_1 106 119 PF00134 0.415
DOC_MAPK_gen_1 68 75 PF00069 0.406
LIG_14-3-3_CanoR_1 37 45 PF00244 0.467
LIG_14-3-3_CanoR_1 6 11 PF00244 0.562
LIG_EH1_1 108 116 PF00400 0.397
LIG_eIF4E_1 109 115 PF01652 0.397
LIG_FHA_2 115 121 PF00498 0.403
LIG_FHA_2 37 43 PF00498 0.499
LIG_LIR_Gen_1 5 15 PF02991 0.397
LIG_LIR_Nem_3 5 10 PF02991 0.405
LIG_NRBOX 68 74 PF00104 0.400
LIG_TRAF2_1 117 120 PF00917 0.513
LIG_UBA3_1 114 123 PF00899 0.470
MOD_CK2_1 114 120 PF00069 0.495
MOD_CK2_1 36 42 PF00069 0.488
MOD_GlcNHglycan 10 13 PF01048 0.530
MOD_GlcNHglycan 39 42 PF01048 0.501
MOD_GSK3_1 2 9 PF00069 0.603
MOD_GSK3_1 20 27 PF00069 0.418
MOD_PIKK_1 99 105 PF00454 0.334
MOD_PKA_1 36 42 PF00069 0.488
MOD_PKA_2 36 42 PF00069 0.476
MOD_SUMO_for_1 105 108 PF00179 0.474
MOD_SUMO_for_1 50 53 PF00179 0.555
MOD_SUMO_for_1 63 66 PF00179 0.393
TRG_DiLeu_BaEn_1 71 76 PF01217 0.392
TRG_DiLeu_BaEn_4 95 101 PF01217 0.416
TRG_ER_diArg_1 86 89 PF00400 0.415
TRG_Pf-PMV_PEXEL_1 116 120 PF00026 0.400

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I6T4 Leptomonas seymouri 82% 100%
A0A0S4JQY9 Bodo saltans 57% 100%
A0A1X0P0D5 Trypanosomatidae 61% 100%
A0A3Q8IJL8 Leishmania donovani 89% 99%
A0A3S5ISR3 Trypanosoma rangeli 63% 100%
A4HPY4 Leishmania braziliensis 76% 100%
A4IDP5 Leishmania infantum 89% 99%
D0A4D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 60% 100%
Q4Q0U7 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS