LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ATM5_LEIMU
TriTrypDb:
LmxM.36.4410
Length:
192

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 7
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATM5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATM5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 179 183 PF00656 0.747
CLV_NRD_NRD_1 107 109 PF00675 0.567
CLV_NRD_NRD_1 146 148 PF00675 0.627
CLV_NRD_NRD_1 2 4 PF00675 0.710
CLV_NRD_NRD_1 63 65 PF00675 0.658
CLV_NRD_NRD_1 71 73 PF00675 0.352
CLV_PCSK_KEX2_1 106 108 PF00082 0.553
CLV_PCSK_KEX2_1 121 123 PF00082 0.421
CLV_PCSK_KEX2_1 129 131 PF00082 0.482
CLV_PCSK_KEX2_1 2 4 PF00082 0.710
CLV_PCSK_KEX2_1 70 72 PF00082 0.490
CLV_PCSK_PC1ET2_1 121 123 PF00082 0.573
CLV_PCSK_PC1ET2_1 129 131 PF00082 0.473
CLV_PCSK_PC1ET2_1 70 72 PF00082 0.540
CLV_PCSK_SKI1_1 115 119 PF00082 0.515
DEG_Nend_UBRbox_1 1 4 PF02207 0.664
DOC_MAPK_gen_1 2 9 PF00069 0.421
DOC_USP7_MATH_1 26 30 PF00917 0.731
DOC_WW_Pin1_4 24 29 PF00397 0.647
DOC_WW_Pin1_4 35 40 PF00397 0.456
LIG_14-3-3_CanoR_1 20 28 PF00244 0.750
LIG_BIR_III_4 182 186 PF00653 0.689
LIG_FHA_1 163 169 PF00498 0.751
LIG_FHA_2 148 154 PF00498 0.465
LIG_FHA_2 57 63 PF00498 0.591
LIG_FHA_2 82 88 PF00498 0.623
LIG_LIR_Apic_2 88 94 PF02991 0.569
LIG_TRAF2_1 93 96 PF00917 0.547
MOD_CK1_1 29 35 PF00069 0.647
MOD_CK1_1 38 44 PF00069 0.730
MOD_CK2_1 147 153 PF00069 0.505
MOD_CK2_1 163 169 PF00069 0.658
MOD_GlcNHglycan 40 43 PF01048 0.714
MOD_GSK3_1 184 191 PF00069 0.742
MOD_GSK3_1 24 31 PF00069 0.545
MOD_NEK2_1 53 58 PF00069 0.604
MOD_PIKK_1 19 25 PF00454 0.627
MOD_PKA_1 147 153 PF00069 0.462
MOD_PKA_2 19 25 PF00069 0.670
MOD_PKA_2 56 62 PF00069 0.612
MOD_PKB_1 145 153 PF00069 0.459
MOD_ProDKin_1 24 30 PF00069 0.648
MOD_ProDKin_1 35 41 PF00069 0.452
TRG_DiLeu_BaEn_4 95 101 PF01217 0.571
TRG_ER_diArg_1 1 3 PF00400 0.728
TRG_ER_diArg_1 106 108 PF00400 0.580
TRG_ER_diArg_1 55 58 PF00400 0.624
TRG_ER_diArg_1 71 74 PF00400 0.501
TRG_Pf-PMV_PEXEL_1 71 75 PF00026 0.651

Homologs

Protein Taxonomy Sequence identity Coverage
A0A1X0P0M8 Trypanosomatidae 57% 100%
A0A3Q8IGG6 Leishmania donovani 87% 99%
A0A3R7P526 Trypanosoma rangeli 53% 100%
A4HPV8 Leishmania braziliensis 75% 100%
A4IDM0 Leishmania infantum 87% 99%
D0A4A7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 48% 100%
Q4Q0X3 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS