LeishMANIAdb
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Proteasome regulatory ATPase subunit

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Proteasome regulatory ATPase subunit
Gene product:
Regulatory particle triple-A ATPase subunit 6
Species:
Leishmania mexicana
UniProt:
E9ATM0_LEIMU
TriTrypDb:
LmxM.36.4360
Length:
409

Annotations

LeishMANIAdb annotations

A large and likely artifical grouping of protease domain carrying proteins related to proteasomal proteases. Only a tiny subgroup (the AFG3-related mitochondrail proteins) seem to have a TM segment.. Localization: Cytoplasmic (by homology) / Mitochondrial (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 6
Silverman et al. no yes: 0
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 6
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 12
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0000502 proteasome complex 3 11
GO:0005737 cytoplasm 2 12
GO:0032991 protein-containing complex 1 12
GO:0110165 cellular anatomical entity 1 12
GO:0140535 intracellular protein-containing complex 2 11
GO:1902494 catalytic complex 2 11
GO:1905368 peptidase complex 3 11
GO:1905369 endopeptidase complex 4 11
GO:0005654 nucleoplasm 2 1
GO:0005838 proteasome regulatory particle 2 1
GO:0008540 proteasome regulatory particle, base subcomplex 2 1

Expansion

Sequence features

E9ATM0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATM0

Function

Biological processes
Term Name Level Count
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009056 catabolic process 2 12
GO:0009057 macromolecule catabolic process 4 12
GO:0019538 protein metabolic process 3 12
GO:0030163 protein catabolic process 4 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044238 primary metabolic process 2 12
GO:0071704 organic substance metabolic process 2 12
GO:1901564 organonitrogen compound metabolic process 3 12
GO:1901565 organonitrogen compound catabolic process 4 12
GO:1901575 organic substance catabolic process 3 12
GO:0006508 proteolysis 4 1
GO:0006511 ubiquitin-dependent protein catabolic process 7 1
GO:0009987 cellular process 1 1
GO:0010498 proteasomal protein catabolic process 5 1
GO:0019941 modification-dependent protein catabolic process 6 1
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 6 1
GO:0043632 modification-dependent macromolecule catabolic process 5 1
GO:0044237 cellular metabolic process 2 1
GO:0044248 cellular catabolic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0044265 obsolete cellular macromolecule catabolic process 4 1
GO:0051603 proteolysis involved in protein catabolic process 5 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0016462 pyrophosphatase activity 5 12
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 12
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 12
GO:0016887 ATP hydrolysis activity 7 12
GO:0017076 purine nucleotide binding 4 12
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 12
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0036402 proteasome-activating activity 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0140657 ATP-dependent activity 1 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 252 256 PF00656 0.345
CLV_C14_Caspase3-7 266 270 PF00656 0.442
CLV_NRD_NRD_1 315 317 PF00675 0.345
CLV_NRD_NRD_1 336 338 PF00675 0.453
CLV_NRD_NRD_1 377 379 PF00675 0.345
CLV_NRD_NRD_1 55 57 PF00675 0.490
CLV_PCSK_FUR_1 375 379 PF00082 0.345
CLV_PCSK_KEX2_1 37 39 PF00082 0.487
CLV_PCSK_KEX2_1 377 379 PF00082 0.345
CLV_PCSK_KEX2_1 55 57 PF00082 0.476
CLV_PCSK_PC1ET2_1 37 39 PF00082 0.487
CLV_PCSK_PC7_1 33 39 PF00082 0.491
CLV_PCSK_SKI1_1 108 112 PF00082 0.379
CLV_PCSK_SKI1_1 115 119 PF00082 0.293
CLV_PCSK_SKI1_1 159 163 PF00082 0.438
CLV_PCSK_SKI1_1 187 191 PF00082 0.345
CLV_PCSK_SKI1_1 199 203 PF00082 0.345
CLV_PCSK_SKI1_1 235 239 PF00082 0.332
CLV_PCSK_SKI1_1 274 278 PF00082 0.342
CLV_PCSK_SKI1_1 290 294 PF00082 0.295
CLV_PCSK_SKI1_1 58 62 PF00082 0.495
DEG_APCC_DBOX_1 273 281 PF00400 0.345
DEG_Nend_Nbox_1 1 3 PF02207 0.744
DEG_SPOP_SBC_1 8 12 PF00917 0.725
DOC_MAPK_gen_1 162 172 PF00069 0.429
DOC_MAPK_gen_1 173 183 PF00069 0.469
DOC_MAPK_gen_1 310 320 PF00069 0.333
DOC_MAPK_MEF2A_6 132 139 PF00069 0.477
DOC_MAPK_MEF2A_6 165 172 PF00069 0.428
DOC_MAPK_MEF2A_6 242 250 PF00069 0.345
DOC_MAPK_NFAT4_5 165 173 PF00069 0.432
DOC_PP1_RVXF_1 101 108 PF00149 0.598
DOC_PP1_RVXF_1 314 321 PF00149 0.345
DOC_PP4_FxxP_1 320 323 PF00568 0.428
DOC_SPAK_OSR1_1 328 332 PF12202 0.441
DOC_USP7_MATH_1 117 121 PF00917 0.534
DOC_USP7_MATH_1 135 139 PF00917 0.481
DOC_USP7_MATH_1 9 13 PF00917 0.649
DOC_USP7_UBL2_3 348 352 PF12436 0.466
DOC_USP7_UBL2_3 392 396 PF12436 0.470
DOC_USP7_UBL2_3 405 409 PF12436 0.591
DOC_USP7_UBL2_3 85 89 PF12436 0.568
DOC_WW_Pin1_4 108 113 PF00397 0.564
DOC_WW_Pin1_4 242 247 PF00397 0.345
LIG_14-3-3_CanoR_1 119 129 PF00244 0.518
LIG_14-3-3_CanoR_1 33 40 PF00244 0.597
LIG_14-3-3_CanoR_1 378 388 PF00244 0.345
LIG_Actin_WH2_2 103 121 PF00022 0.504
LIG_Actin_WH2_2 297 312 PF00022 0.345
LIG_BRCT_BRCA1_1 103 107 PF00533 0.542
LIG_BRCT_BRCA1_1 21 25 PF00533 0.513
LIG_BRCT_BRCA1_1 246 250 PF00533 0.361
LIG_Clathr_ClatBox_1 139 143 PF01394 0.502
LIG_FHA_1 120 126 PF00498 0.518
LIG_FHA_1 340 346 PF00498 0.477
LIG_FHA_2 129 135 PF00498 0.573
LIG_FHA_2 148 154 PF00498 0.472
LIG_FHA_2 273 279 PF00498 0.372
LIG_FHA_2 380 386 PF00498 0.345
LIG_HP1_1 135 139 PF01393 0.487
LIG_LIR_Apic_2 319 323 PF02991 0.334
LIG_LIR_Gen_1 148 157 PF02991 0.473
LIG_LIR_Gen_1 211 222 PF02991 0.345
LIG_LIR_Gen_1 41 48 PF02991 0.486
LIG_LIR_LC3C_4 70 75 PF02991 0.589
LIG_LIR_Nem_3 104 110 PF02991 0.606
LIG_LIR_Nem_3 148 154 PF02991 0.486
LIG_LIR_Nem_3 211 217 PF02991 0.345
LIG_LIR_Nem_3 41 46 PF02991 0.492
LIG_MLH1_MIPbox_1 21 25 PF16413 0.513
LIG_PCNA_yPIPBox_3 18 28 PF02747 0.569
LIG_PCNA_yPIPBox_3 396 408 PF02747 0.636
LIG_SH2_CRK 192 196 PF00017 0.345
LIG_SH2_NCK_1 151 155 PF00017 0.464
LIG_SH2_PTP2 127 130 PF00017 0.493
LIG_SH2_SRC 151 154 PF00017 0.472
LIG_SH2_STAT3 24 27 PF00017 0.485
LIG_SH2_STAT5 127 130 PF00017 0.493
LIG_SH2_STAT5 226 229 PF00017 0.345
LIG_SH2_STAT5 24 27 PF00017 0.472
LIG_SH3_3 169 175 PF00018 0.438
LIG_SH3_3 2 8 PF00018 0.772
LIG_SUMO_SIM_anti_2 275 281 PF11976 0.332
LIG_SUMO_SIM_par_1 97 102 PF11976 0.493
LIG_UBA3_1 331 338 PF00899 0.437
MOD_CDK_SPxxK_3 108 115 PF00069 0.579
MOD_CK1_1 10 16 PF00069 0.708
MOD_CK1_1 120 126 PF00069 0.564
MOD_CK1_1 256 262 PF00069 0.338
MOD_CK1_1 355 361 PF00069 0.466
MOD_CK2_1 147 153 PF00069 0.494
MOD_CK2_1 215 221 PF00069 0.345
MOD_CK2_1 257 263 PF00069 0.358
MOD_CK2_1 272 278 PF00069 0.301
MOD_CK2_1 355 361 PF00069 0.376
MOD_GlcNHglycan 119 122 PF01048 0.334
MOD_GlcNHglycan 217 220 PF01048 0.345
MOD_GlcNHglycan 263 266 PF01048 0.410
MOD_GlcNHglycan 357 360 PF01048 0.334
MOD_GlcNHglycan 69 72 PF01048 0.491
MOD_GlcNHglycan 91 94 PF01048 0.335
MOD_GSK3_1 10 17 PF00069 0.641
MOD_GSK3_1 253 260 PF00069 0.345
MOD_GSK3_1 32 39 PF00069 0.582
MOD_GSK3_1 351 358 PF00069 0.345
MOD_N-GLC_1 339 344 PF02516 0.463
MOD_N-GLC_1 355 360 PF02516 0.338
MOD_N-GLC_1 400 405 PF02516 0.612
MOD_NEK2_1 286 291 PF00069 0.345
MOD_NEK2_1 32 37 PF00069 0.571
MOD_NEK2_1 339 344 PF00069 0.475
MOD_NEK2_1 67 72 PF00069 0.504
MOD_PIKK_1 32 38 PF00454 0.539
MOD_PKA_1 352 358 PF00069 0.466
MOD_PKA_2 215 221 PF00069 0.343
MOD_PKA_2 32 38 PF00069 0.593
MOD_Plk_1 101 107 PF00069 0.504
MOD_Plk_1 147 153 PF00069 0.519
MOD_Plk_1 210 216 PF00069 0.332
MOD_Plk_1 400 406 PF00069 0.561
MOD_Plk_4 135 141 PF00069 0.476
MOD_Plk_4 197 203 PF00069 0.345
MOD_Plk_4 210 216 PF00069 0.345
MOD_Plk_4 244 250 PF00069 0.345
MOD_Plk_4 69 75 PF00069 0.507
MOD_ProDKin_1 108 114 PF00069 0.564
MOD_ProDKin_1 242 248 PF00069 0.345
MOD_SUMO_for_1 140 143 PF00179 0.497
MOD_SUMO_for_1 60 63 PF00179 0.499
MOD_SUMO_rev_2 100 110 PF00179 0.561
MOD_SUMO_rev_2 158 167 PF00179 0.440
MOD_SUMO_rev_2 355 365 PF00179 0.359
TRG_AP2beta_CARGO_1 41 50 PF09066 0.605
TRG_DiLeu_BaEn_1 69 74 PF01217 0.604
TRG_DiLeu_BaEn_4 62 68 PF01217 0.541
TRG_ENDOCYTIC_2 151 154 PF00928 0.472
TRG_ER_diArg_1 377 379 PF00400 0.345
TRG_ER_diArg_1 55 58 PF00400 0.492
TRG_ER_diLys_1 405 409 PF00400 0.607
TRG_Pf-PMV_PEXEL_1 58 62 PF00026 0.499

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4E9 Leptomonas seymouri 46% 100%
A0A0N0P5B8 Leptomonas seymouri 53% 92%
A0A0N0P7K1 Leptomonas seymouri 95% 100%
A0A0N1IGY9 Leptomonas seymouri 44% 98%
A0A0N1IM81 Leptomonas seymouri 54% 93%
A0A0N1PAS8 Leptomonas seymouri 50% 94%
A0A0S4IJE6 Bodo saltans 51% 94%
A0A0S4ITX1 Bodo saltans 51% 92%
A0A0S4IY28 Bodo saltans 50% 100%
A0A0S4JDU3 Bodo saltans 84% 100%
A0A0S4JSD8 Bodo saltans 46% 100%
A0A0S4KLG9 Bodo saltans 35% 81%
A0A1X0NMZ3 Trypanosomatidae 52% 94%
A0A1X0NNS1 Trypanosomatidae 42% 99%
A0A1X0NT86 Trypanosomatidae 49% 93%
A0A1X0NUX3 Trypanosomatidae 50% 94%
A0A1X0P1T5 Trypanosomatidae 85% 100%
A0A1X0P749 Trypanosomatidae 35% 72%
A0A1X0P8T7 Trypanosomatidae 46% 100%
A0A3Q8IJS0 Leishmania donovani 100% 100%
A0A3R7LUG9 Trypanosoma rangeli 52% 93%
A0A3R7N4Y5 Trypanosoma rangeli 85% 100%
A0A3S5H547 Leishmania donovani 46% 100%
A0A3S7WRY0 Leishmania donovani 44% 100%
A0A3S7WSK7 Leishmania donovani 54% 93%
A0A3S7WX14 Leishmania donovani 53% 92%
A0A3S7WX46 Leishmania donovani 51% 94%
A0A422NDS9 Trypanosoma rangeli 51% 94%
A0A422NLD8 Trypanosoma rangeli 52% 94%
A0A422NMN6 Trypanosoma rangeli 47% 100%
A0A422NUD9 Trypanosoma rangeli 46% 100%
A0A422P1K0 Trypanosoma rangeli 35% 73%
A1A0U4 Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) 36% 79%
A1SK07 Nocardioides sp. (strain ATCC BAA-499 / JS614) 38% 70%
A3CV35 Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) 45% 99%
A4FBX6 Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) 37% 69%
A4G0S4 Methanococcus maripaludis (strain C5 / ATCC BAA-1333) 48% 100%
A4H3L6 Leishmania braziliensis 48% 100%
A4H6T6 Leishmania braziliensis 44% 100%
A4H795 Leishmania braziliensis 54% 100%
A4HCA3 Leishmania braziliensis 51% 100%
A4HCA7 Leishmania braziliensis 53% 92%
A4HG81 Leishmania braziliensis 35% 78%
A4HPV3 Leishmania braziliensis 98% 100%
A4HVN7 Leishmania infantum 54% 93%
A4HZT4 Leishmania infantum 51% 94%
A4HZT9 Leishmania infantum 53% 92%
A4I3C0 Leishmania infantum 35% 68%
A4IE38 Leishmania infantum 100% 100%
A4QE83 Corynebacterium glutamicum (strain R) 36% 78%
A6UQT3 Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) 48% 100%
A6VHR1 Methanococcus maripaludis (strain C7 / ATCC BAA-1331) 48% 100%
A7I8B8 Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8) 49% 94%
A9A916 Methanococcus maripaludis (strain C6 / ATCC BAA-1332) 48% 100%
B1VDV2 Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) 38% 76%
B3EX35 Sorex araneus 39% 83%
B6YXR2 Thermococcus onnurineus (strain NA1) 46% 100%
B8GGN4 Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) 47% 99%
C3MRF1 Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) 47% 100%
C3MY47 Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) 47% 100%
C3MZI6 Sulfolobus islandicus (strain M.16.27) 47% 100%
C3N7K8 Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) 47% 100%
C3NFW6 Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) 47% 100%
C4KIR6 Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) 47% 100%
C5A6P8 Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) 50% 100%
C7R400 Jonesia denitrificans (strain ATCC 14870 / DSM 20603 / BCRC 15368 / CIP 55.134 / JCM 11481 / NBRC 15587 / NCTC 10816 / Prevot 55134) 36% 74%
C9ZQC1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
C9ZRM0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 51% 94%
C9ZRM8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 50% 92%
C9ZZX3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 72%
D0A259 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 47% 100%
D0A4A2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 83% 100%
D0A6K9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 53% 94%
D0A6N0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 72%
D2NT89 Rothia mucilaginosa (strain DY-18) 36% 67%
D2Q9C6 Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1) 33% 77%
D4GUJ7 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) 42% 100%
E9ACJ9 Leishmania major 45% 100%
E9AG43 Leishmania infantum 46% 100%
E9AGB0 Leishmania infantum 44% 100%
E9AJT7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 45% 100%
E9ANU8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 44% 100%
E9APD3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%
E9AVN9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 51% 94%
E9AVP4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 52% 92%
E9AZK1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 76%
O04019 Arabidopsis thaliana 51% 97%
O14126 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 43% 93%
O16368 Caenorhabditis elegans 52% 92%
O17071 Caenorhabditis elegans 45% 100%
O18413 Drosophila melanogaster 73% 100%
O23894 Brassica campestris 44% 96%
O26824 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 52% 100%
O28303 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) 51% 100%
O42586 Xenopus laevis 46% 100%
O42587 Xenopus laevis 46% 97%
O42931 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 54% 93%
O57940 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 52% 100%
O64982 Prunus persica 51% 96%
O74445 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 47% 100%
O74894 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 43% 100%
O76371 Caenorhabditis elegans 42% 95%
O88685 Mus musculus 46% 93%
P0DKJ9 Oryza sativa subsp. japonica 51% 96%
P0DKK0 Oryza sativa subsp. japonica 51% 96%
P17980 Homo sapiens 46% 93%
P33297 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 42% 94%
P33298 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 42% 96%
P33299 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 55% 88%
P34123 Dictyostelium discoideum 46% 100%
P34124 Dictyostelium discoideum 70% 100%
P35998 Homo sapiens 56% 94%
P36612 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 46% 91%
P40327 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 52% 94%
P41836 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 70% 100%
P43686 Homo sapiens 40% 98%
P46465 Oryza sativa subsp. japonica 45% 95%
P46466 Oryza sativa subsp. japonica 47% 91%
P46470 Xenopus laevis 73% 89%
P46471 Mus musculus 56% 94%
P46472 Xenopus laevis 56% 94%
P46502 Caenorhabditis elegans 41% 99%
P46507 Manduca sexta 43% 99%
P48601 Drosophila melanogaster 46% 93%
P53549 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 47% 94%
P54775 Mus musculus 40% 98%
P54776 Solanum lycopersicum 45% 97%
P54778 Solanum tuberosum 46% 99%
P54814 Manduca sexta 73% 100%
P62191 Homo sapiens 49% 93%
P62192 Mus musculus 49% 93%
P62193 Rattus norvegicus 49% 93%
P62194 Bos taurus 74% 100%
P62195 Homo sapiens 74% 100%
P62196 Mus musculus 74% 100%
P62197 Sus scrofa 74% 100%
P62198 Rattus norvegicus 74% 100%
P62333 Homo sapiens 50% 100%
P62334 Mus musculus 50% 100%
P62335 Ictidomys tridecemlineatus 50% 100%
P78578 Aspergillus niger 45% 97%
P85200 Helianthus annuus 44% 99%
Q01939 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 67% 100%
Q0W257 Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) 49% 98%
Q18787 Caenorhabditis elegans 56% 94%
Q25544 Naegleria fowleri 70% 99%
Q2FQ56 Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) 49% 99%
Q2KIW6 Bos taurus 50% 100%
Q3T030 Bos taurus 40% 98%
Q41365 Spinacia oleracea 51% 96%
Q4Q0X8 Leishmania major 99% 100%
Q4Q8N0 Leishmania major 33% 75%
Q4QBT5 Leishmania major 52% 92%
Q4QBU0 Leishmania major 51% 100%
Q4QG45 Leishmania major 54% 100%
Q4QGS2 Leishmania major 44% 100%
Q4R4R0 Macaca fascicularis 56% 94%
Q4R7L3 Macaca fascicularis 40% 98%
Q54PJ1 Dictyostelium discoideum 48% 100%
Q54PN7 Dictyostelium discoideum 46% 97%
Q55BV5 Dictyostelium discoideum 46% 93%
Q58576 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 53% 95%
Q5E9F9 Bos taurus 56% 94%
Q5JHS5 Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) 52% 100%
Q5R8D7 Pongo abelii 56% 94%
Q5UT56 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) 40% 99%
Q63347 Rattus norvegicus 56% 94%
Q63569 Rattus norvegicus 46% 93%
Q63570 Rattus norvegicus 40% 98%
Q6LWR0 Methanococcus maripaludis (strain S2 / LL) 49% 100%
Q6NH92 Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) 37% 80%
Q86JA1 Dictyostelium discoideum 50% 96%
Q8FTE3 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) 36% 78%
Q8NQD8 Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) 36% 78%
Q8PY58 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) 47% 97%
Q8SQI9 Encephalitozoon cuniculi (strain GB-M1) 45% 100%
Q8SQK0 Encephalitozoon cuniculi (strain GB-M1) 67% 100%
Q8SR13 Encephalitozoon cuniculi (strain GB-M1) 44% 100%
Q8SRH0 Encephalitozoon cuniculi (strain GB-M1) 53% 96%
Q8TI88 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) 48% 97%
Q8TX03 Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) 51% 94%
Q8U4H3 Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) 52% 100%
Q90732 Gallus gallus 48% 93%
Q94BQ2 Arabidopsis thaliana 75% 98%
Q975U2 Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) 47% 100%
Q980M1 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) 46% 100%
Q9C5U3 Arabidopsis thaliana 74% 98%
Q9HNP9 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 48% 100%
Q9HRW6 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 44% 100%
Q9MAK9 Arabidopsis thaliana 47% 100%
Q9SEI2 Arabidopsis thaliana 45% 96%
Q9SEI3 Arabidopsis thaliana 47% 100%
Q9SEI4 Arabidopsis thaliana 44% 100%
Q9SL67 Arabidopsis thaliana 46% 92%
Q9SSB4 Arabidopsis thaliana 50% 88%
Q9SSB5 Arabidopsis thaliana 51% 96%
Q9SZD4 Arabidopsis thaliana 46% 92%
Q9V287 Pyrococcus abyssi (strain GE5 / Orsay) 51% 100%
Q9XTT9 Caenorhabditis elegans 68% 98%
Q9YAC7 Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) 50% 100%
V5AV12 Trypanosoma cruzi 52% 94%
V5B5X1 Trypanosoma cruzi 50% 94%
V5B5X6 Trypanosoma cruzi 52% 93%
V5BKL6 Trypanosoma cruzi 86% 100%
V5BSS5 Trypanosoma cruzi 46% 100%
V5DBR1 Trypanosoma cruzi 35% 69%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS