Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATL9_LEIMU

TriTrypDb:

LmxM.36.4350

Length:

892

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATL9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATL9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	10	14	PF00656	0.501
CLV_C14_Caspase3-7	141	145	PF00656	0.798
CLV_C14_Caspase3-7	424	428	PF00656	0.653
CLV_C14_Caspase3-7	503	507	PF00656	0.550
CLV_C14_Caspase3-7	741	745	PF00656	0.742
CLV_MEL_PAP_1	599	605	PF00089	0.756
CLV_NRD_NRD_1	149	151	PF00675	0.808
CLV_NRD_NRD_1	459	461	PF00675	0.721
CLV_NRD_NRD_1	686	688	PF00675	0.613
CLV_NRD_NRD_1	756	758	PF00675	0.722
CLV_NRD_NRD_1	763	765	PF00675	0.664
CLV_NRD_NRD_1	889	891	PF00675	0.747
CLV_PCSK_FUR_1	754	758	PF00082	0.677
CLV_PCSK_KEX2_1	149	151	PF00082	0.808
CLV_PCSK_KEX2_1	590	592	PF00082	0.724
CLV_PCSK_KEX2_1	688	690	PF00082	0.611
CLV_PCSK_KEX2_1	753	755	PF00082	0.692
CLV_PCSK_KEX2_1	756	758	PF00082	0.689
CLV_PCSK_KEX2_1	762	764	PF00082	0.689
CLV_PCSK_PC1ET2_1	590	592	PF00082	0.724
CLV_PCSK_PC1ET2_1	688	690	PF00082	0.668
CLV_PCSK_PC1ET2_1	753	755	PF00082	0.692
CLV_PCSK_SKI1_1	374	378	PF00082	0.816
CLV_PCSK_SKI1_1	429	433	PF00082	0.783
CLV_PCSK_SKI1_1	591	595	PF00082	0.725
DEG_APCC_DBOX_1	761	769	PF00400	0.796
DEG_SCF_FBW7_1	876	882	PF00400	0.807
DEG_SCF_FBW7_1	884	889	PF00400	0.720
DEG_SPOP_SBC_1	565	569	PF00917	0.747
DEG_SPOP_SBC_1	791	795	PF00917	0.535
DOC_CKS1_1	24	29	PF01111	0.784
DOC_CKS1_1	610	615	PF01111	0.527
DOC_CKS1_1	876	881	PF01111	0.823
DOC_CKS1_1	94	99	PF01111	0.707
DOC_CYCLIN_RxL_1	584	598	PF00134	0.724
DOC_CYCLIN_yClb1_LxF_4	589	594	PF00134	0.817
DOC_CYCLIN_yCln2_LP_2	359	365	PF00134	0.537
DOC_PP1_RVXF_1	33	40	PF00149	0.797
DOC_PP1_RVXF_1	588	595	PF00149	0.717
DOC_PP2B_LxvP_1	359	362	PF13499	0.641
DOC_PP4_FxxP_1	21	24	PF00568	0.800
DOC_USP7_MATH_1	124	128	PF00917	0.724
DOC_USP7_MATH_1	159	163	PF00917	0.722
DOC_USP7_MATH_1	166	170	PF00917	0.767
DOC_USP7_MATH_1	179	183	PF00917	0.512
DOC_USP7_MATH_1	22	26	PF00917	0.631
DOC_USP7_MATH_1	247	251	PF00917	0.756
DOC_USP7_MATH_1	4	8	PF00917	0.532
DOC_USP7_MATH_1	416	420	PF00917	0.819
DOC_USP7_MATH_1	482	486	PF00917	0.651
DOC_USP7_MATH_1	505	509	PF00917	0.719
DOC_USP7_MATH_1	672	676	PF00917	0.521
DOC_USP7_MATH_1	715	719	PF00917	0.698
DOC_USP7_MATH_1	74	78	PF00917	0.689
DOC_USP7_MATH_1	792	796	PF00917	0.633
DOC_USP7_MATH_1	842	846	PF00917	0.807
DOC_USP7_MATH_1	886	890	PF00917	0.837
DOC_WW_Pin1_4	131	136	PF00397	0.684
DOC_WW_Pin1_4	200	205	PF00397	0.635
DOC_WW_Pin1_4	215	220	PF00397	0.536
DOC_WW_Pin1_4	23	28	PF00397	0.792
DOC_WW_Pin1_4	281	286	PF00397	0.725
DOC_WW_Pin1_4	42	47	PF00397	0.490
DOC_WW_Pin1_4	467	472	PF00397	0.697
DOC_WW_Pin1_4	542	547	PF00397	0.727
DOC_WW_Pin1_4	583	588	PF00397	0.692
DOC_WW_Pin1_4	605	610	PF00397	0.672
DOC_WW_Pin1_4	837	842	PF00397	0.817
DOC_WW_Pin1_4	875	880	PF00397	0.817
DOC_WW_Pin1_4	882	887	PF00397	0.723
DOC_WW_Pin1_4	90	95	PF00397	0.713
LIG_14-3-3_CanoR_1	149	155	PF00244	0.724
LIG_14-3-3_CanoR_1	167	171	PF00244	0.626
LIG_14-3-3_CanoR_1	185	190	PF00244	0.462
LIG_14-3-3_CanoR_1	211	215	PF00244	0.614
LIG_14-3-3_CanoR_1	275	285	PF00244	0.757
LIG_14-3-3_CanoR_1	295	300	PF00244	0.691
LIG_14-3-3_CanoR_1	335	343	PF00244	0.679
LIG_14-3-3_CanoR_1	38	46	PF00244	0.510
LIG_14-3-3_CanoR_1	702	708	PF00244	0.593
LIG_BIR_III_4	714	718	PF00653	0.527
LIG_BRCT_BRCA1_1	17	21	PF00533	0.812
LIG_FHA_1	149	155	PF00498	0.689
LIG_FHA_1	185	191	PF00498	0.681
LIG_FHA_1	211	217	PF00498	0.735
LIG_FHA_1	220	226	PF00498	0.621
LIG_FHA_1	438	444	PF00498	0.715
LIG_FHA_1	610	616	PF00498	0.529
LIG_FHA_2	232	238	PF00498	0.611
LIG_FHA_2	302	308	PF00498	0.734
LIG_FHA_2	418	424	PF00498	0.693
LIG_FHA_2	531	537	PF00498	0.533
LIG_FHA_2	567	573	PF00498	0.783
LIG_FHA_2	731	737	PF00498	0.733
LIG_FHA_2	773	779	PF00498	0.744
LIG_FHA_2	820	826	PF00498	0.794
LIG_Integrin_isoDGR_2	372	374	PF01839	0.752
LIG_Integrin_RGD_1	366	368	PF01839	0.522
LIG_LIR_Apic_2	18	24	PF02991	0.804
LIG_LIR_Gen_1	375	384	PF02991	0.515
LIG_LIR_Gen_1	451	459	PF02991	0.567
LIG_LIR_Gen_1	733	742	PF02991	0.798
LIG_LIR_Gen_1	829	836	PF02991	0.739
LIG_LIR_Nem_3	311	315	PF02991	0.715
LIG_LIR_Nem_3	375	380	PF02991	0.729
LIG_LIR_Nem_3	451	455	PF02991	0.689
LIG_LIR_Nem_3	733	738	PF02991	0.794
LIG_LIR_Nem_3	829	833	PF02991	0.700
LIG_MYND_1	609	613	PF01753	0.811
LIG_Pex14_1	660	664	PF04695	0.804
LIG_SH2_CRK	186	190	PF00017	0.504
LIG_SH2_NCK_1	125	129	PF00017	0.496
LIG_SH2_STAP1	125	129	PF00017	0.496
LIG_SH2_STAP1	186	190	PF00017	0.504
LIG_SH2_STAT3	259	262	PF00017	0.798
LIG_SH2_STAT5	186	189	PF00017	0.500
LIG_SH2_STAT5	259	262	PF00017	0.742
LIG_SH3_3	21	27	PF00018	0.796
LIG_SH3_3	282	288	PF00018	0.738
LIG_SH3_3	337	343	PF00018	0.680
LIG_SH3_3	52	58	PF00018	0.521
LIG_SH3_3	550	556	PF00018	0.823
LIG_SH3_3	873	879	PF00018	0.687
LIG_SH3_3	91	97	PF00018	0.705
LIG_TRAF2_1	234	237	PF00917	0.573
LIG_TRAF2_1	419	422	PF00917	0.756
LIG_TRAF2_1	57	60	PF00917	0.732
LIG_TRAF2_1	593	596	PF00917	0.725
LIG_TRAF2_1	66	69	PF00917	0.629
LIG_WRC_WIRS_1	391	396	PF05994	0.503
MOD_CDK_SPK_2	585	590	PF00069	0.799
MOD_CDK_SPK_2	93	98	PF00069	0.808
MOD_CDK_SPxK_1	585	591	PF00069	0.803
MOD_CDK_SPxxK_3	542	549	PF00069	0.830
MOD_CDK_SPxxK_3	583	590	PF00069	0.695
MOD_CDK_SPxxK_3	609	616	PF00069	0.528
MOD_CK1_1	120	126	PF00069	0.757
MOD_CK1_1	134	140	PF00069	0.591
MOD_CK1_1	155	161	PF00069	0.794
MOD_CK1_1	205	211	PF00069	0.656
MOD_CK1_1	277	283	PF00069	0.662
MOD_CK1_1	347	353	PF00069	0.805
MOD_CK1_1	525	531	PF00069	0.684
MOD_CK1_1	542	548	PF00069	0.498
MOD_CK1_1	567	573	PF00069	0.660
MOD_CK1_1	582	588	PF00069	0.542
MOD_CK1_1	7	13	PF00069	0.739
MOD_CK1_1	793	799	PF00069	0.672
MOD_CK1_1	831	837	PF00069	0.730
MOD_CK1_1	843	849	PF00069	0.717
MOD_CK1_1	869	875	PF00069	0.697
MOD_CK1_1	93	99	PF00069	0.739
MOD_CK2_1	172	178	PF00069	0.506
MOD_CK2_1	22	28	PF00069	0.687
MOD_CK2_1	231	237	PF00069	0.611
MOD_CK2_1	400	406	PF00069	0.577
MOD_CK2_1	416	422	PF00069	0.793
MOD_CK2_1	530	536	PF00069	0.530
MOD_CK2_1	566	572	PF00069	0.793
MOD_CK2_1	730	736	PF00069	0.805
MOD_GlcNHglycan	126	129	PF01048	0.659
MOD_GlcNHglycan	157	160	PF01048	0.788
MOD_GlcNHglycan	17	20	PF01048	0.627
MOD_GlcNHglycan	190	193	PF01048	0.679
MOD_GlcNHglycan	204	207	PF01048	0.649
MOD_GlcNHglycan	266	269	PF01048	0.648
MOD_GlcNHglycan	394	397	PF01048	0.740
MOD_GlcNHglycan	412	415	PF01048	0.701
MOD_GlcNHglycan	467	470	PF01048	0.769
MOD_GlcNHglycan	495	498	PF01048	0.768
MOD_GlcNHglycan	524	527	PF01048	0.731
MOD_GlcNHglycan	6	9	PF01048	0.787
MOD_GlcNHglycan	632	635	PF01048	0.738
MOD_GlcNHglycan	661	664	PF01048	0.712
MOD_GlcNHglycan	666	669	PF01048	0.645
MOD_GlcNHglycan	678	681	PF01048	0.520
MOD_GlcNHglycan	708	711	PF01048	0.574
MOD_GlcNHglycan	803	806	PF01048	0.717
MOD_GlcNHglycan	871	874	PF01048	0.699
MOD_GSK3_1	120	127	PF00069	0.784
MOD_GSK3_1	134	141	PF00069	0.565
MOD_GSK3_1	148	155	PF00069	0.778
MOD_GSK3_1	184	191	PF00069	0.763
MOD_GSK3_1	193	200	PF00069	0.597
MOD_GSK3_1	215	222	PF00069	0.719
MOD_GSK3_1	277	284	PF00069	0.675
MOD_GSK3_1	38	45	PF00069	0.639
MOD_GSK3_1	390	397	PF00069	0.792
MOD_GSK3_1	417	424	PF00069	0.737
MOD_GSK3_1	463	470	PF00069	0.708
MOD_GSK3_1	471	478	PF00069	0.725
MOD_GSK3_1	505	512	PF00069	0.727
MOD_GSK3_1	579	586	PF00069	0.684
MOD_GSK3_1	605	612	PF00069	0.671
MOD_GSK3_1	672	679	PF00069	0.796
MOD_GSK3_1	702	709	PF00069	0.646
MOD_GSK3_1	786	793	PF00069	0.694
MOD_GSK3_1	797	804	PF00069	0.728
MOD_GSK3_1	828	835	PF00069	0.736
MOD_GSK3_1	840	847	PF00069	0.713
MOD_GSK3_1	871	878	PF00069	0.667
MOD_GSK3_1	882	889	PF00069	0.789
MOD_GSK3_1	96	103	PF00069	0.798
MOD_N-GLC_1	289	294	PF02516	0.809
MOD_N-GLC_1	448	453	PF02516	0.695
MOD_N-GLC_1	882	887	PF02516	0.707
MOD_N-GLC_2	199	201	PF02516	0.763
MOD_NEK2_1	111	116	PF00069	0.695
MOD_NEK2_1	15	20	PF00069	0.738
MOD_NEK2_1	255	260	PF00069	0.707
MOD_NEK2_1	276	281	PF00069	0.694
MOD_NEK2_1	344	349	PF00069	0.715
MOD_NEK2_1	376	381	PF00069	0.604
MOD_NEK2_1	390	395	PF00069	0.720
MOD_NEK2_1	399	404	PF00069	0.673
MOD_NEK2_1	448	453	PF00069	0.555
MOD_NEK2_1	515	520	PF00069	0.754
MOD_NEK2_1	653	658	PF00069	0.700
MOD_NEK2_1	664	669	PF00069	0.700
MOD_NEK2_1	683	688	PF00069	0.456
MOD_NEK2_1	797	802	PF00069	0.667
MOD_NEK2_2	579	584	PF00069	0.782
MOD_PIKK_1	258	264	PF00454	0.793
MOD_PIKK_1	328	334	PF00454	0.700
MOD_PIKK_1	394	400	PF00454	0.689
MOD_PIKK_1	40	46	PF00454	0.529
MOD_PIKK_1	482	488	PF00454	0.539
MOD_PIKK_1	828	834	PF00454	0.689
MOD_PIKK_1	840	846	PF00454	0.713
MOD_PIKK_1	855	861	PF00454	0.609
MOD_PIKK_1	871	877	PF00454	0.568
MOD_PKA_2	148	154	PF00069	0.707
MOD_PKA_2	15	21	PF00069	0.775
MOD_PKA_2	166	172	PF00069	0.710
MOD_PKA_2	184	190	PF00069	0.461
MOD_PKA_2	210	216	PF00069	0.633
MOD_PKA_2	271	277	PF00069	0.680
MOD_PKA_2	294	300	PF00069	0.688
MOD_PKA_2	301	307	PF00069	0.696
MOD_PKA_2	334	340	PF00069	0.641
MOD_PKA_2	559	565	PF00069	0.758
MOD_PKA_2	715	721	PF00069	0.614
MOD_PKB_1	150	158	PF00069	0.808
MOD_PKB_1	687	695	PF00069	0.482
MOD_Plk_1	159	165	PF00069	0.654
MOD_Plk_1	289	295	PF00069	0.776
MOD_Plk_1	354	360	PF00069	0.825
MOD_Plk_4	134	140	PF00069	0.691
MOD_Plk_4	185	191	PF00069	0.783
MOD_Plk_4	354	360	PF00069	0.728
MOD_Plk_4	703	709	PF00069	0.723
MOD_Plk_4	793	799	PF00069	0.646
MOD_ProDKin_1	131	137	PF00069	0.686
MOD_ProDKin_1	200	206	PF00069	0.633
MOD_ProDKin_1	215	221	PF00069	0.533
MOD_ProDKin_1	23	29	PF00069	0.789
MOD_ProDKin_1	281	287	PF00069	0.724
MOD_ProDKin_1	42	48	PF00069	0.493
MOD_ProDKin_1	467	473	PF00069	0.697
MOD_ProDKin_1	542	548	PF00069	0.727
MOD_ProDKin_1	583	589	PF00069	0.692
MOD_ProDKin_1	605	611	PF00069	0.671
MOD_ProDKin_1	837	843	PF00069	0.816
MOD_ProDKin_1	875	881	PF00069	0.820
MOD_ProDKin_1	882	888	PF00069	0.720
MOD_ProDKin_1	90	96	PF00069	0.716
MOD_SUMO_rev_2	318	325	PF00179	0.738
TRG_DiLeu_BaEn_1	354	359	PF01217	0.761
TRG_DiLeu_BaEn_1	595	600	PF01217	0.781
TRG_DiLeu_BaEn_4	354	360	PF01217	0.763
TRG_DiLeu_BaLyEn_6	386	391	PF01217	0.508
TRG_ENDOCYTIC_2	186	189	PF00928	0.500
TRG_ER_diArg_1	148	150	PF00400	0.802
TRG_ER_diArg_1	299	302	PF00400	0.811
TRG_ER_diArg_1	684	687	PF00400	0.613
TRG_ER_diArg_1	754	757	PF00400	0.799
TRG_ER_diArg_1	762	764	PF00400	0.658
TRG_NLS_MonoExtC_3	752	757	PF00514	0.694
TRG_NLS_MonoExtN_4	685	691	PF00514	0.667
TRG_Pf-PMV_PEXEL_1	689	693	PF00026	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P766	Leptomonas seymouri	31%	100%
A0A3S7XBG5	Leishmania donovani	81%	100%
A4HPV2	Leishmania braziliensis	58%	99%
A4IE39	Leishmania infantum	81%	100%
Q4Q0X9	Leishmania major	80%	100%