Amastin_surface_glycoprotein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Amastin surface glycoprotein, putative

Species:

Leishmania mexicana

UniProt:

E9ATJ6_LEIMU

TriTrypDb:

LmxM.36.4130

Length:

237

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

E9ATJ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATJ6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	6	8	PF00675	0.491
CLV_PCSK_KEX2_1	11	13	PF00082	0.556
CLV_PCSK_KEX2_1	6	8	PF00082	0.491
CLV_PCSK_PC1ET2_1	11	13	PF00082	0.556
CLV_PCSK_PC7_1	7	13	PF00082	0.543
CLV_PCSK_SKI1_1	133	137	PF00082	0.633
CLV_PCSK_SKI1_1	164	168	PF00082	0.435
CLV_PCSK_SKI1_1	29	33	PF00082	0.423
CLV_PCSK_SKI1_1	6	10	PF00082	0.370
DEG_APCC_DBOX_1	163	171	PF00400	0.512
DEG_APCC_DBOX_1	28	36	PF00400	0.423
DOC_CKS1_1	52	57	PF01111	0.528
DOC_MAPK_DCC_7	164	172	PF00069	0.550
DOC_MAPK_MEF2A_6	102	109	PF00069	0.443
DOC_MAPK_MEF2A_6	164	172	PF00069	0.512
DOC_PP2B_LxvP_1	210	213	PF13499	0.241
DOC_PP2B_PxIxI_1	54	60	PF00149	0.530
DOC_PP4_FxxP_1	52	55	PF00568	0.443
DOC_USP7_MATH_1	206	210	PF00917	0.401
DOC_WW_Pin1_4	51	56	PF00397	0.442
LIG_Actin_WH2_2	15	31	PF00022	0.550
LIG_BRCT_BRCA1_1	158	162	PF00533	0.384
LIG_EH1_1	226	234	PF00400	0.423
LIG_eIF4E_1	227	233	PF01652	0.376
LIG_FHA_1	147	153	PF00498	0.467
LIG_FHA_1	224	230	PF00498	0.423
LIG_FHA_1	52	58	PF00498	0.531
LIG_FHA_1	89	95	PF00498	0.437
LIG_LIR_Gen_1	159	170	PF02991	0.446
LIG_LIR_Nem_3	108	114	PF02991	0.497
LIG_LIR_Nem_3	131	135	PF02991	0.466
LIG_LIR_Nem_3	146	151	PF02991	0.305
LIG_LIR_Nem_3	163	169	PF02991	0.668
LIG_LIR_Nem_3	76	81	PF02991	0.528
LIG_MLH1_MIPbox_1	158	162	PF16413	0.423
LIG_NRBOX	38	44	PF00104	0.491
LIG_PDZ_Class_2	232	237	PF00595	0.423
LIG_Pex14_2	132	136	PF04695	0.468
LIG_Pex14_2	162	166	PF04695	0.659
LIG_Pex14_2	217	221	PF04695	0.491
LIG_REV1ctd_RIR_1	133	141	PF16727	0.519
LIG_REV1ctd_RIR_1	159	167	PF16727	0.582
LIG_SH2_CRK	111	115	PF00017	0.526
LIG_SH2_STAT3	122	125	PF00017	0.468
LIG_SH2_STAT5	227	230	PF00017	0.423
LIG_SH2_STAT5	36	39	PF00017	0.423
LIG_SH3_3	104	110	PF00018	0.435
LIG_SUMO_SIM_par_1	143	149	PF11976	0.423
LIG_TYR_ITIM	109	114	PF00017	0.514
LIG_TYR_ITIM	34	39	PF00017	0.491
MOD_CDK_SPxxK_3	51	58	PF00069	0.531
MOD_CK1_1	143	149	PF00069	0.423
MOD_CK1_1	231	237	PF00069	0.393
MOD_CK1_1	53	59	PF00069	0.500
MOD_GSK3_1	156	163	PF00069	0.423
MOD_GSK3_1	174	181	PF00069	0.166
MOD_GSK3_1	223	230	PF00069	0.306
MOD_N-GLC_1	116	121	PF02516	0.723
MOD_N-GLC_1	88	93	PF02516	0.605
MOD_NEK2_1	156	161	PF00069	0.388
MOD_NEK2_1	174	179	PF00069	0.166
MOD_NEK2_1	180	185	PF00069	0.398
MOD_NEK2_1	228	233	PF00069	0.423
MOD_NEK2_1	98	103	PF00069	0.475
MOD_NEK2_2	21	26	PF00069	0.472
MOD_PIKK_1	116	122	PF00454	0.523
MOD_Plk_1	116	122	PF00069	0.513
MOD_Plk_1	62	68	PF00069	0.376
MOD_Plk_1	81	87	PF00069	0.286
MOD_Plk_4	143	149	PF00069	0.423
MOD_Plk_4	21	27	PF00069	0.393
MOD_Plk_4	223	229	PF00069	0.423
MOD_Plk_4	231	237	PF00069	0.423
MOD_Plk_4	69	75	PF00069	0.447
MOD_Plk_4	81	87	PF00069	0.395
MOD_ProDKin_1	51	57	PF00069	0.441
TRG_DiLeu_BaLyEn_6	165	170	PF01217	0.550
TRG_ENDOCYTIC_2	111	114	PF00928	0.503
TRG_ENDOCYTIC_2	198	201	PF00928	0.513
TRG_ENDOCYTIC_2	36	39	PF00928	0.423
TRG_NES_CRM1_1	202	215	PF08389	0.350
TRG_Pf-PMV_PEXEL_1	190	194	PF00026	0.741

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA59	Leptomonas seymouri	64%	100%
A0A1X0P3I9	Trypanosomatidae	34%	100%
A0A3S7XBG4	Leishmania donovani	92%	100%
A4IE61	Leishmania infantum	92%	100%
Q4Q102	Leishmania major	91%	100%