Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATJ2_LEIMU

TriTrypDb:

LmxM.36.4090

Length:

432

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATJ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATJ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	56	60	PF00656	0.802
CLV_NRD_NRD_1	133	135	PF00675	0.558
CLV_NRD_NRD_1	237	239	PF00675	0.715
CLV_NRD_NRD_1	334	336	PF00675	0.675
CLV_NRD_NRD_1	390	392	PF00675	0.525
CLV_NRD_NRD_1	396	398	PF00675	0.571
CLV_PCSK_FUR_1	278	282	PF00082	0.762
CLV_PCSK_KEX2_1	133	135	PF00082	0.633
CLV_PCSK_KEX2_1	28	30	PF00082	0.462
CLV_PCSK_KEX2_1	280	282	PF00082	0.837
CLV_PCSK_KEX2_1	334	336	PF00082	0.574
CLV_PCSK_KEX2_1	396	398	PF00082	0.697
CLV_PCSK_PC1ET2_1	28	30	PF00082	0.462
CLV_PCSK_PC1ET2_1	280	282	PF00082	0.837
CLV_PCSK_SKI1_1	255	259	PF00082	0.753
CLV_PCSK_SKI1_1	29	33	PF00082	0.747
CLV_PCSK_SKI1_1	419	423	PF00082	0.629
DEG_MDM2_SWIB_1	158	165	PF02201	0.596
DEG_Nend_UBRbox_1	1	4	PF02207	0.787
DEG_SPOP_SBC_1	51	55	PF00917	0.727
DOC_CYCLIN_yCln2_LP_2	135	141	PF00134	0.648
DOC_CYCLIN_yCln2_LP_2	31	34	PF00134	0.750
DOC_MAPK_DCC_7	293	303	PF00069	0.718
DOC_PP2B_LxvP_1	135	138	PF13499	0.650
DOC_PP2B_LxvP_1	265	268	PF13499	0.821
DOC_PP2B_LxvP_1	31	34	PF13499	0.750
DOC_USP7_MATH_1	120	124	PF00917	0.648
DOC_USP7_MATH_1	126	130	PF00917	0.534
DOC_USP7_MATH_1	139	143	PF00917	0.329
DOC_USP7_MATH_1	197	201	PF00917	0.690
DOC_USP7_MATH_1	289	293	PF00917	0.754
DOC_USP7_MATH_1	341	345	PF00917	0.778
DOC_USP7_MATH_1	351	355	PF00917	0.719
DOC_USP7_MATH_1	359	363	PF00917	0.594
DOC_USP7_MATH_1	364	368	PF00917	0.590
DOC_USP7_MATH_1	51	55	PF00917	0.805
DOC_USP7_MATH_1	82	86	PF00917	0.364
DOC_WW_Pin1_4	189	194	PF00397	0.536
DOC_WW_Pin1_4	205	210	PF00397	0.769
DOC_WW_Pin1_4	213	218	PF00397	0.637
DOC_WW_Pin1_4	32	37	PF00397	0.726
LIG_14-3-3_CanoR_1	199	209	PF00244	0.707
LIG_14-3-3_CanoR_1	2	9	PF00244	0.652
LIG_14-3-3_CanoR_1	86	92	PF00244	0.516
LIG_BRCT_BRCA1_1	154	158	PF00533	0.595
LIG_EVH1_2	68	72	PF00568	0.744
LIG_FHA_1	114	120	PF00498	0.632
LIG_FHA_1	17	23	PF00498	0.585
LIG_FHA_1	298	304	PF00498	0.698
LIG_FHA_2	35	41	PF00498	0.690
LIG_FHA_2	54	60	PF00498	0.803
LIG_LIR_Gen_1	155	166	PF02991	0.601
LIG_LIR_Nem_3	159	165	PF02991	0.544
LIG_NRBOX	40	46	PF00104	0.701
LIG_PCNA_yPIPBox_3	408	422	PF02747	0.696
LIG_Pex14_2	127	131	PF04695	0.622
LIG_Pex14_2	154	158	PF04695	0.595
LIG_SH2_NCK_1	9	13	PF00017	0.481
LIG_SH2_STAT3	149	152	PF00017	0.474
LIG_SH2_STAT5	410	413	PF00017	0.695
LIG_SH3_3	116	122	PF00018	0.646
LIG_SH3_3	211	217	PF00018	0.706
LIG_SH3_3	253	259	PF00018	0.619
LIG_SH3_3	30	36	PF00018	0.733
LIG_SH3_3	314	320	PF00018	0.657
LIG_SUMO_SIM_anti_2	300	305	PF11976	0.695
LIG_SUMO_SIM_par_1	216	223	PF11976	0.549
LIG_SUMO_SIM_par_1	373	378	PF11976	0.751
MOD_CK1_1	189	195	PF00069	0.819
MOD_CK1_1	200	206	PF00069	0.616
MOD_CK1_1	223	229	PF00069	0.554
MOD_CK1_1	247	253	PF00069	0.559
MOD_CK1_1	27	33	PF00069	0.459
MOD_CK1_1	354	360	PF00069	0.681
MOD_CK1_1	362	368	PF00069	0.614
MOD_CK1_1	5	11	PF00069	0.776
MOD_CK1_1	73	79	PF00069	0.620
MOD_CK2_1	34	40	PF00069	0.703
MOD_CK2_1	417	423	PF00069	0.608
MOD_Cter_Amidation	278	281	PF01082	0.839
MOD_GlcNHglycan	10	13	PF01048	0.518
MOD_GlcNHglycan	154	157	PF01048	0.313
MOD_GlcNHglycan	204	207	PF01048	0.855
MOD_GlcNHglycan	222	225	PF01048	0.533
MOD_GlcNHglycan	241	244	PF01048	0.742
MOD_GlcNHglycan	246	249	PF01048	0.649
MOD_GlcNHglycan	250	253	PF01048	0.621
MOD_GlcNHglycan	287	290	PF01048	0.750
MOD_GlcNHglycan	330	333	PF01048	0.790
MOD_GlcNHglycan	342	346	PF01048	0.686
MOD_GlcNHglycan	356	359	PF01048	0.631
MOD_GlcNHglycan	370	373	PF01048	0.576
MOD_GlcNHglycan	47	50	PF01048	0.760
MOD_GlcNHglycan	72	75	PF01048	0.715
MOD_GSK3_1	109	116	PF00069	0.600
MOD_GSK3_1	152	159	PF00069	0.595
MOD_GSK3_1	182	189	PF00069	0.512
MOD_GSK3_1	197	204	PF00069	0.678
MOD_GSK3_1	219	226	PF00069	0.560
MOD_GSK3_1	244	251	PF00069	0.697
MOD_GSK3_1	285	292	PF00069	0.663
MOD_GSK3_1	364	371	PF00069	0.711
MOD_GSK3_1	53	60	PF00069	0.648
MOD_GSK3_1	68	75	PF00069	0.546
MOD_GSK3_1	82	89	PF00069	0.368
MOD_N-GLC_1	248	253	PF02516	0.681
MOD_NEK2_1	107	112	PF00069	0.415
MOD_NEK2_1	114	119	PF00069	0.485
MOD_NEK2_1	218	223	PF00069	0.748
MOD_NEK2_1	233	238	PF00069	0.630
MOD_NEK2_1	45	50	PF00069	0.745
MOD_NEK2_1	72	77	PF00069	0.516
MOD_NEK2_2	139	144	PF00069	0.642
MOD_PKA_2	198	204	PF00069	0.681
MOD_Plk_1	16	22	PF00069	0.616
MOD_Plk_1	186	192	PF00069	0.527
MOD_Plk_4	95	101	PF00069	0.618
MOD_ProDKin_1	189	195	PF00069	0.538
MOD_ProDKin_1	205	211	PF00069	0.767
MOD_ProDKin_1	213	219	PF00069	0.643
MOD_ProDKin_1	32	38	PF00069	0.717
MOD_SUMO_rev_2	174	182	PF00179	0.711
MOD_SUMO_rev_2	357	365	PF00179	0.740
TRG_DiLeu_BaEn_1	178	183	PF01217	0.620
TRG_DiLeu_BaEn_1	40	45	PF01217	0.618
TRG_DiLeu_BaLyEn_6	167	172	PF01217	0.716
TRG_DiLeu_BaLyEn_6	214	219	PF01217	0.526
TRG_DiLeu_BaLyEn_6	253	258	PF01217	0.756
TRG_ER_diArg_1	133	135	PF00400	0.633
TRG_ER_diArg_1	334	336	PF00400	0.564
TRG_ER_diArg_1	395	397	PF00400	0.700
TRG_NES_CRM1_1	373	384	PF08389	0.438
TRG_Pf-PMV_PEXEL_1	180	184	PF00026	0.717

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ILA1	Leishmania donovani	85%	100%
A4HPS7	Leishmania braziliensis	67%	100%
A4IE65	Leishmania infantum	85%	100%
Q4Q106	Leishmania major	84%	100%