Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ATH8_LEIMU

TriTrypDb:

LmxM.36.3960

Length:

1015

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATH8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATH8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	322	326	PF00656	0.700
CLV_C14_Caspase3-7	751	755	PF00656	0.508
CLV_NRD_NRD_1	1002	1004	PF00675	0.716
CLV_NRD_NRD_1	357	359	PF00675	0.700
CLV_NRD_NRD_1	509	511	PF00675	0.696
CLV_NRD_NRD_1	539	541	PF00675	0.649
CLV_NRD_NRD_1	62	64	PF00675	0.659
CLV_NRD_NRD_1	748	750	PF00675	0.576
CLV_NRD_NRD_1	931	933	PF00675	0.679
CLV_PCSK_FUR_1	229	233	PF00082	0.590
CLV_PCSK_FUR_1	537	541	PF00082	0.649
CLV_PCSK_KEX2_1	1002	1004	PF00082	0.763
CLV_PCSK_KEX2_1	231	233	PF00082	0.620
CLV_PCSK_KEX2_1	357	359	PF00082	0.628
CLV_PCSK_KEX2_1	361	363	PF00082	0.600
CLV_PCSK_KEX2_1	410	412	PF00082	0.581
CLV_PCSK_KEX2_1	509	511	PF00082	0.690
CLV_PCSK_KEX2_1	539	541	PF00082	0.624
CLV_PCSK_KEX2_1	748	750	PF00082	0.576
CLV_PCSK_KEX2_1	890	892	PF00082	0.576
CLV_PCSK_KEX2_1	931	933	PF00082	0.757
CLV_PCSK_PC1ET2_1	231	233	PF00082	0.595
CLV_PCSK_PC1ET2_1	361	363	PF00082	0.619
CLV_PCSK_PC1ET2_1	410	412	PF00082	0.552
CLV_PCSK_PC1ET2_1	890	892	PF00082	0.566
CLV_PCSK_PC7_1	357	363	PF00082	0.613
CLV_PCSK_PC7_1	998	1004	PF00082	0.703
CLV_PCSK_SKI1_1	576	580	PF00082	0.648
CLV_PCSK_SKI1_1	770	774	PF00082	0.657
CLV_PCSK_SKI1_1	796	800	PF00082	0.572
DEG_SCF_FBW7_1	452	459	PF00400	0.686
DEG_SPOP_SBC_1	149	153	PF00917	0.649
DOC_CKS1_1	21	26	PF01111	0.692
DOC_CKS1_1	486	491	PF01111	0.546
DOC_CKS1_1	494	499	PF01111	0.533
DOC_CKS1_1	590	595	PF01111	0.526
DOC_CYCLIN_RxL_1	793	802	PF00134	0.571
DOC_CYCLIN_yCln2_LP_2	137	143	PF00134	0.629
DOC_CYCLIN_yCln2_LP_2	971	977	PF00134	0.533
DOC_MAPK_DCC_7	380	390	PF00069	0.518
DOC_MAPK_HePTP_8	245	257	PF00069	0.588
DOC_MAPK_MEF2A_6	248	257	PF00069	0.599
DOC_PP2B_LxvP_1	137	140	PF13499	0.758
DOC_PP2B_LxvP_1	146	149	PF13499	0.583
DOC_PP2B_LxvP_1	438	441	PF13499	0.545
DOC_PP2B_LxvP_1	568	571	PF13499	0.676
DOC_PP2B_LxvP_1	971	974	PF13499	0.539
DOC_PP4_FxxP_1	531	534	PF00568	0.736
DOC_PP4_FxxP_1	580	583	PF00568	0.600
DOC_USP7_MATH_1	131	135	PF00917	0.707
DOC_USP7_MATH_1	149	153	PF00917	0.474
DOC_USP7_MATH_1	184	188	PF00917	0.715
DOC_USP7_MATH_1	321	325	PF00917	0.554
DOC_USP7_MATH_1	39	43	PF00917	0.648
DOC_USP7_MATH_1	418	422	PF00917	0.715
DOC_USP7_MATH_1	447	451	PF00917	0.651
DOC_USP7_MATH_1	457	461	PF00917	0.636
DOC_USP7_MATH_1	525	529	PF00917	0.677
DOC_USP7_MATH_1	564	568	PF00917	0.690
DOC_USP7_MATH_1	677	681	PF00917	0.618
DOC_USP7_MATH_1	722	726	PF00917	0.593
DOC_USP7_MATH_1	96	100	PF00917	0.696
DOC_USP7_MATH_1	960	964	PF00917	0.729
DOC_USP7_MATH_1	980	984	PF00917	0.612
DOC_USP7_MATH_2	757	763	PF00917	0.508
DOC_USP7_MATH_2	9	15	PF00917	0.613
DOC_WW_Pin1_4	141	146	PF00397	0.596
DOC_WW_Pin1_4	20	25	PF00397	0.748
DOC_WW_Pin1_4	31	36	PF00397	0.620
DOC_WW_Pin1_4	334	339	PF00397	0.652
DOC_WW_Pin1_4	344	349	PF00397	0.614
DOC_WW_Pin1_4	364	369	PF00397	0.497
DOC_WW_Pin1_4	424	429	PF00397	0.685
DOC_WW_Pin1_4	452	457	PF00397	0.668
DOC_WW_Pin1_4	485	490	PF00397	0.605
DOC_WW_Pin1_4	493	498	PF00397	0.600
DOC_WW_Pin1_4	521	526	PF00397	0.657
DOC_WW_Pin1_4	530	535	PF00397	0.714
DOC_WW_Pin1_4	552	557	PF00397	0.613
DOC_WW_Pin1_4	566	571	PF00397	0.663
DOC_WW_Pin1_4	586	591	PF00397	0.502
DOC_WW_Pin1_4	856	861	PF00397	0.608
DOC_WW_Pin1_4	866	871	PF00397	0.628
DOC_WW_Pin1_4	922	927	PF00397	0.719
LIG_14-3-3_CanoR_1	154	162	PF00244	0.646
LIG_14-3-3_CanoR_1	190	199	PF00244	0.567
LIG_14-3-3_CanoR_1	206	210	PF00244	0.619
LIG_14-3-3_CanoR_1	232	236	PF00244	0.596
LIG_14-3-3_CanoR_1	380	388	PF00244	0.524
LIG_14-3-3_CanoR_1	458	466	PF00244	0.643
LIG_14-3-3_CanoR_1	537	543	PF00244	0.709
LIG_14-3-3_CanoR_1	57	62	PF00244	0.633
LIG_14-3-3_CanoR_1	576	581	PF00244	0.646
LIG_14-3-3_CanoR_1	63	73	PF00244	0.663
LIG_14-3-3_CanoR_1	654	664	PF00244	0.665
LIG_14-3-3_CanoR_1	698	702	PF00244	0.521
LIG_14-3-3_CanoR_1	708	712	PF00244	0.523
LIG_Actin_WH2_2	561	578	PF00022	0.675
LIG_BIR_III_2	754	758	PF00653	0.515
LIG_BIR_III_4	824	828	PF00653	0.500
LIG_BRCT_BRCA1_1	486	490	PF00533	0.549
LIG_BRCT_BRCA1_1	527	531	PF00533	0.737
LIG_BRCT_BRCA1_1	641	645	PF00533	0.529
LIG_BRCT_BRCA1_1	984	988	PF00533	0.508
LIG_CtBP_PxDLS_1	435	439	PF00389	0.695
LIG_FHA_1	100	106	PF00498	0.601
LIG_FHA_1	297	303	PF00498	0.497
LIG_FHA_1	32	38	PF00498	0.719
LIG_FHA_1	373	379	PF00498	0.726
LIG_FHA_1	380	386	PF00498	0.533
LIG_FHA_1	466	472	PF00498	0.702
LIG_FHA_1	579	585	PF00498	0.684
LIG_FHA_1	636	642	PF00498	0.485
LIG_FHA_1	660	666	PF00498	0.707
LIG_FHA_1	682	688	PF00498	0.631
LIG_FHA_2	302	308	PF00498	0.535
LIG_FHA_2	477	483	PF00498	0.537
LIG_FHA_2	711	717	PF00498	0.599
LIG_FHA_2	769	775	PF00498	0.678
LIG_FHA_2	812	818	PF00498	0.608
LIG_HCF-1_HBM_1	846	849	PF13415	0.694
LIG_LIR_Apic_2	528	534	PF02991	0.737
LIG_LIR_Apic_2	577	583	PF02991	0.734
LIG_LIR_Gen_1	642	652	PF02991	0.566
LIG_LIR_Gen_1	709	719	PF02991	0.487
LIG_LIR_Gen_1	985	995	PF02991	0.562
LIG_LIR_Nem_3	700	706	PF02991	0.409
LIG_LIR_Nem_3	883	889	PF02991	0.573
LIG_MYND_1	344	348	PF01753	0.645
LIG_SH2_STAT5	830	833	PF00017	0.797
LIG_SH2_STAT5	855	858	PF00017	0.657
LIG_SH2_STAT5	928	931	PF00017	0.545
LIG_SH2_STAT5	993	996	PF00017	0.583
LIG_SH3_1	411	417	PF00018	0.538
LIG_SH3_1	788	794	PF00018	0.642
LIG_SH3_2	649	654	PF14604	0.480
LIG_SH3_2	791	796	PF14604	0.582
LIG_SH3_3	139	145	PF00018	0.632
LIG_SH3_3	210	216	PF00018	0.684
LIG_SH3_3	332	338	PF00018	0.837
LIG_SH3_3	385	391	PF00018	0.536
LIG_SH3_3	411	417	PF00018	0.679
LIG_SH3_3	425	431	PF00018	0.589
LIG_SH3_3	488	494	PF00018	0.664
LIG_SH3_3	550	556	PF00018	0.562
LIG_SH3_3	587	593	PF00018	0.520
LIG_SH3_3	646	652	PF00018	0.523
LIG_SH3_3	74	80	PF00018	0.644
LIG_SH3_3	788	794	PF00018	0.605
LIG_SH3_3	971	977	PF00018	0.705
LIG_TRAF2_1	320	323	PF00917	0.751
LIG_TRAF2_1	460	463	PF00917	0.695
LIG_TRAF2_1	599	602	PF00917	0.713
LIG_TRAF2_1	742	745	PF00917	0.523
LIG_WW_3	429	433	PF00397	0.533
LIG_WW_3	455	459	PF00397	0.611
LIG_WW_3	793	797	PF00397	0.584
MOD_CDC14_SPxK_1	367	370	PF00782	0.677
MOD_CDK_SPK_2	31	36	PF00069	0.543
MOD_CDK_SPK_2	493	498	PF00069	0.545
MOD_CDK_SPxK_1	364	370	PF00069	0.674
MOD_CDK_SPxK_1	426	432	PF00069	0.546
MOD_CDK_SPxK_1	452	458	PF00069	0.684
MOD_CDK_SPxK_1	866	872	PF00069	0.714
MOD_CDK_SPxxK_3	485	492	PF00069	0.606
MOD_CDK_SPxxK_3	530	537	PF00069	0.685
MOD_CK1_1	123	129	PF00069	0.781
MOD_CK1_1	14	20	PF00069	0.748
MOD_CK1_1	153	159	PF00069	0.706
MOD_CK1_1	160	166	PF00069	0.649
MOD_CK1_1	271	277	PF00069	0.585
MOD_CK1_1	306	312	PF00069	0.688
MOD_CK1_1	334	340	PF00069	0.788
MOD_CK1_1	422	428	PF00069	0.665
MOD_CK1_1	472	478	PF00069	0.686
MOD_CK1_1	505	511	PF00069	0.751
MOD_CK1_1	555	561	PF00069	0.702
MOD_CK1_1	627	633	PF00069	0.595
MOD_CK1_1	67	73	PF00069	0.735
MOD_CK1_1	680	686	PF00069	0.669
MOD_CK1_1	859	865	PF00069	0.657
MOD_CK1_1	964	970	PF00069	0.651
MOD_CK1_1	99	105	PF00069	0.714
MOD_CK2_1	231	237	PF00069	0.488
MOD_CK2_1	321	327	PF00069	0.686
MOD_CK2_1	344	350	PF00069	0.638
MOD_CK2_1	389	395	PF00069	0.760
MOD_CK2_1	457	463	PF00069	0.719
MOD_CK2_1	476	482	PF00069	0.537
MOD_CK2_1	710	716	PF00069	0.510
MOD_CK2_1	740	746	PF00069	0.632
MOD_CK2_1	811	817	PF00069	0.599
MOD_CK2_1	932	938	PF00069	0.773
MOD_DYRK1A_RPxSP_1	364	368	PF00069	0.619
MOD_GlcNHglycan	122	125	PF01048	0.712
MOD_GlcNHglycan	133	136	PF01048	0.607
MOD_GlcNHglycan	16	19	PF01048	0.751
MOD_GlcNHglycan	271	274	PF01048	0.552
MOD_GlcNHglycan	310	313	PF01048	0.690
MOD_GlcNHglycan	41	44	PF01048	0.598
MOD_GlcNHglycan	471	474	PF01048	0.744
MOD_GlcNHglycan	510	513	PF01048	0.614
MOD_GlcNHglycan	596	599	PF01048	0.598
MOD_GlcNHglycan	622	625	PF01048	0.591
MOD_GlcNHglycan	66	69	PF01048	0.683
MOD_GlcNHglycan	675	678	PF01048	0.694
MOD_GlcNHglycan	679	682	PF01048	0.666
MOD_GlcNHglycan	689	692	PF01048	0.572
MOD_GlcNHglycan	724	727	PF01048	0.523
MOD_GlcNHglycan	801	804	PF01048	0.552
MOD_GlcNHglycan	81	84	PF01048	0.641
MOD_GlcNHglycan	838	841	PF01048	0.684
MOD_GlcNHglycan	920	923	PF01048	0.691
MOD_GlcNHglycan	933	937	PF01048	0.579
MOD_GlcNHglycan	984	987	PF01048	0.598
MOD_GSK3_1	105	112	PF00069	0.584
MOD_GSK3_1	149	156	PF00069	0.739
MOD_GSK3_1	173	180	PF00069	0.640
MOD_GSK3_1	186	193	PF00069	0.615
MOD_GSK3_1	253	260	PF00069	0.481
MOD_GSK3_1	301	308	PF00069	0.584
MOD_GSK3_1	405	412	PF00069	0.747
MOD_GSK3_1	418	425	PF00069	0.603
MOD_GSK3_1	447	454	PF00069	0.706
MOD_GSK3_1	465	472	PF00069	0.742
MOD_GSK3_1	498	505	PF00069	0.649
MOD_GSK3_1	521	528	PF00069	0.696
MOD_GSK3_1	538	545	PF00069	0.565
MOD_GSK3_1	574	581	PF00069	0.643
MOD_GSK3_1	620	627	PF00069	0.643
MOD_GSK3_1	63	70	PF00069	0.735
MOD_GSK3_1	635	642	PF00069	0.476
MOD_GSK3_1	655	662	PF00069	0.488
MOD_GSK3_1	673	680	PF00069	0.774
MOD_GSK3_1	706	713	PF00069	0.519
MOD_GSK3_1	764	771	PF00069	0.654
MOD_GSK3_1	847	854	PF00069	0.607
MOD_GSK3_1	859	866	PF00069	0.620
MOD_GSK3_1	918	925	PF00069	0.685
MOD_GSK3_1	96	103	PF00069	0.688
MOD_GSK3_1	960	967	PF00069	0.730
MOD_N-GLC_1	109	114	PF02516	0.552
MOD_N-GLC_1	281	286	PF02516	0.500
MOD_N-GLC_1	419	424	PF02516	0.748
MOD_N-GLC_1	964	969	PF02516	0.543
MOD_N-GLC_1	99	104	PF02516	0.591
MOD_N-GLC_2	4	6	PF02516	0.690
MOD_NEK2_1	150	155	PF00069	0.704
MOD_NEK2_1	185	190	PF00069	0.660
MOD_NEK2_1	305	310	PF00069	0.571
MOD_NEK2_1	451	456	PF00069	0.728
MOD_NEK2_1	594	599	PF00069	0.651
MOD_NEK2_1	635	640	PF00069	0.525
MOD_NEK2_1	687	692	PF00069	0.626
MOD_NEK2_1	706	711	PF00069	0.396
MOD_NEK2_1	715	720	PF00069	0.513
MOD_NEK2_2	926	931	PF00069	0.537
MOD_OFUCOSY	761	768	PF10250	0.507
MOD_PIKK_1	17	23	PF00454	0.699
MOD_PIKK_1	409	415	PF00454	0.752
MOD_PIKK_1	465	471	PF00454	0.675
MOD_PIKK_1	659	665	PF00454	0.679
MOD_PIKK_1	964	970	PF00454	0.678
MOD_PK_1	231	237	PF00069	0.547
MOD_PKA_1	231	237	PF00069	0.605
MOD_PKA_1	409	415	PF00069	0.752
MOD_PKA_1	63	69	PF00069	0.689
MOD_PKA_2	153	159	PF00069	0.644
MOD_PKA_2	205	211	PF00069	0.643
MOD_PKA_2	231	237	PF00069	0.605
MOD_PKA_2	253	259	PF00069	0.520
MOD_PKA_2	379	385	PF00069	0.517
MOD_PKA_2	457	463	PF00069	0.705
MOD_PKA_2	508	514	PF00069	0.554
MOD_PKA_2	538	544	PF00069	0.699
MOD_PKA_2	62	68	PF00069	0.681
MOD_PKA_2	697	703	PF00069	0.524
MOD_PKA_2	707	713	PF00069	0.517
MOD_PKA_2	811	817	PF00069	0.549
MOD_PKA_2	851	857	PF00069	0.616
MOD_PKA_2	997	1003	PF00069	0.697
MOD_PKB_1	360	368	PF00069	0.642
MOD_PKB_1	55	63	PF00069	0.580
MOD_Plk_1	109	115	PF00069	0.586
MOD_Plk_1	422	428	PF00069	0.756
MOD_Plk_1	447	453	PF00069	0.686
MOD_Plk_1	628	634	PF00069	0.524
MOD_Plk_1	706	712	PF00069	0.573
MOD_Plk_1	715	721	PF00069	0.455
MOD_Plk_1	845	851	PF00069	0.603
MOD_Plk_1	99	105	PF00069	0.661
MOD_Plk_2-3	323	329	PF00069	0.620
MOD_Plk_4	100	106	PF00069	0.517
MOD_Plk_4	157	163	PF00069	0.601
MOD_Plk_4	281	287	PF00069	0.513
MOD_Plk_4	447	453	PF00069	0.740
MOD_Plk_4	526	532	PF00069	0.740
MOD_Plk_4	615	621	PF00069	0.654
MOD_Plk_4	707	713	PF00069	0.514
MOD_Plk_4	851	857	PF00069	0.616
MOD_ProDKin_1	141	147	PF00069	0.596
MOD_ProDKin_1	20	26	PF00069	0.747
MOD_ProDKin_1	31	37	PF00069	0.620
MOD_ProDKin_1	334	340	PF00069	0.651
MOD_ProDKin_1	344	350	PF00069	0.611
MOD_ProDKin_1	364	370	PF00069	0.499
MOD_ProDKin_1	424	430	PF00069	0.679
MOD_ProDKin_1	452	458	PF00069	0.671
MOD_ProDKin_1	485	491	PF00069	0.603
MOD_ProDKin_1	493	499	PF00069	0.600
MOD_ProDKin_1	521	527	PF00069	0.654
MOD_ProDKin_1	530	536	PF00069	0.712
MOD_ProDKin_1	552	558	PF00069	0.613
MOD_ProDKin_1	566	572	PF00069	0.662
MOD_ProDKin_1	586	592	PF00069	0.504
MOD_ProDKin_1	856	862	PF00069	0.606
MOD_ProDKin_1	866	872	PF00069	0.633
MOD_ProDKin_1	922	928	PF00069	0.723
MOD_SUMO_rev_2	325	335	PF00179	0.551
MOD_SUMO_rev_2	950	960	PF00179	0.651
TRG_DiLeu_BaLyEn_6	210	215	PF01217	0.613
TRG_DiLeu_BaLyEn_6	341	346	PF01217	0.669
TRG_DiLeu_BaLyEn_6	869	874	PF01217	0.669
TRG_ENDOCYTIC_2	750	753	PF00928	0.587
TRG_ENDOCYTIC_2	889	892	PF00928	0.570
TRG_ER_diArg_1	1001	1003	PF00400	0.656
TRG_ER_diArg_1	357	360	PF00400	0.605
TRG_ER_diArg_1	536	539	PF00400	0.651
TRG_ER_diArg_1	55	58	PF00400	0.651
TRG_ER_diArg_1	748	750	PF00400	0.576
TRG_ER_diArg_1	930	932	PF00400	0.779
TRG_ER_diArg_1	995	998	PF00400	0.665
TRG_NLS_MonoExtC_3	359	364	PF00514	0.640
TRG_NLS_MonoExtN_4	357	364	PF00514	0.702
TRG_Pf-PMV_PEXEL_1	872	877	PF00026	0.724

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEK5	Leptomonas seymouri	34%	100%
A0A3Q8IIW4	Leishmania donovani	86%	100%
A4HPR4	Leishmania braziliensis	66%	100%
A4ID00	Leishmania infantum	86%	100%
Q4Q119	Leishmania major	85%	100%