Cilia- and flagella-associated protein 157

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATH7_LEIMU

TriTrypDb:

LmxM.36.3950

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATH7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATH7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	13	15	PF00675	0.498
CLV_NRD_NRD_1	208	210	PF00675	0.444
CLV_NRD_NRD_1	99	101	PF00675	0.409
CLV_PCSK_FUR_1	129	133	PF00082	0.468
CLV_PCSK_KEX2_1	13	15	PF00082	0.560
CLV_PCSK_KEX2_1	131	133	PF00082	0.514
CLV_PCSK_KEX2_1	49	51	PF00082	0.489
CLV_PCSK_PC1ET2_1	131	133	PF00082	0.514
CLV_PCSK_PC1ET2_1	49	51	PF00082	0.485
CLV_Separin_Metazoa	2	6	PF03568	0.519
CLV_Separin_Metazoa	92	96	PF03568	0.459
DEG_APCC_DBOX_1	204	212	PF00400	0.447
DEG_Nend_UBRbox_2	1	3	PF02207	0.504
DOC_CKS1_1	145	150	PF01111	0.522
DOC_MAPK_gen_1	209	219	PF00069	0.495
DOC_MAPK_gen_1	86	93	PF00069	0.524
DOC_USP7_MATH_1	141	145	PF00917	0.451
DOC_WW_Pin1_4	144	149	PF00397	0.514
LIG_14-3-3_CanoR_1	149	155	PF00244	0.573
LIG_14-3-3_CanoR_1	54	63	PF00244	0.486
LIG_Actin_WH2_2	59	76	PF00022	0.484
LIG_APCC_ABBAyCdc20_2	52	58	PF00400	0.481
LIG_FHA_1	174	180	PF00498	0.478
LIG_FHA_2	150	156	PF00498	0.446
LIG_GBD_Chelix_1	47	55	PF00786	0.476
LIG_LIR_LC3C_4	176	180	PF02991	0.478
LIG_NRBOX	215	221	PF00104	0.464
LIG_PCNA_yPIPBox_3	13	22	PF02747	0.591
LIG_SH2_STAP1	98	102	PF00017	0.461
LIG_SH2_STAT5	238	241	PF00017	0.473
LIG_SUMO_SIM_par_1	218	224	PF11976	0.398
LIG_TRAF2_1	224	227	PF00917	0.465
LIG_WRC_WIRS_1	222	227	PF05994	0.412
MOD_CDK_SPK_2	144	149	PF00069	0.514
MOD_CK1_1	144	150	PF00069	0.504
MOD_CK2_1	102	108	PF00069	0.403
MOD_CK2_1	149	155	PF00069	0.397
MOD_CK2_1	221	227	PF00069	0.460
MOD_CK2_1	58	64	PF00069	0.603
MOD_CK2_1	73	79	PF00069	0.450
MOD_CK2_1	86	92	PF00069	0.357
MOD_GlcNHglycan	201	204	PF01048	0.658
MOD_GlcNHglycan	33	36	PF01048	0.640
MOD_GSK3_1	195	202	PF00069	0.541
MOD_GSK3_1	54	61	PF00069	0.646
MOD_N-GLC_1	150	155	PF02516	0.663
MOD_NEK2_1	120	125	PF00069	0.448
MOD_NEK2_1	178	183	PF00069	0.627
MOD_NEK2_1	31	36	PF00069	0.482
MOD_NEK2_2	141	146	PF00069	0.458
MOD_PKA_1	86	92	PF00069	0.452
MOD_PKB_1	52	60	PF00069	0.483
MOD_Plk_1	150	156	PF00069	0.584
MOD_Plk_1	173	179	PF00069	0.538
MOD_Plk_1	78	84	PF00069	0.372
MOD_Plk_2-3	221	227	PF00069	0.406
MOD_Plk_2-3	58	64	PF00069	0.492
MOD_Plk_4	184	190	PF00069	0.603
MOD_ProDKin_1	144	150	PF00069	0.517
MOD_SUMO_for_1	114	117	PF00179	0.487
MOD_SUMO_for_1	130	133	PF00179	0.595
MOD_SUMO_for_1	25	28	PF00179	0.496
MOD_SUMO_rev_2	79	89	PF00179	0.466
TRG_DiLeu_BaEn_1	174	179	PF01217	0.472
TRG_DiLeu_BaEn_1	212	217	PF01217	0.495
TRG_ER_diArg_1	13	16	PF00400	0.496
TRG_ER_diArg_1	51	54	PF00400	0.521
TRG_NES_CRM1_1	155	167	PF08389	0.344
TRG_Pf-PMV_PEXEL_1	158	162	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	16	20	PF00026	0.528

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4JLH7	Bodo saltans	38%	71%
A0A3S7XBE4	Leishmania donovani	94%	100%
A4ID01	Leishmania infantum	94%	88%
Q4Q120	Leishmania major	94%	100%
V5B6W3	Trypanosoma cruzi	46%	88%