FtsX-like permease family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATH4_LEIMU

TriTrypDb:

LmxM.36.3920

Length:

133

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

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Expansion

Sequence features

E9ATH4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATH4

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	34	38	PF00082	0.379
CLV_PCSK_SKI1_1	76	80	PF00082	0.458
DEG_APCC_DBOX_1	33	41	PF00400	0.543
DEG_APCC_DBOX_1	75	83	PF00400	0.272
DEG_SPOP_SBC_1	49	53	PF00917	0.259
DOC_USP7_MATH_1	124	128	PF00917	0.663
LIG_BRCT_BRCA1_1	46	50	PF00533	0.376
LIG_EVH1_2	70	74	PF00568	0.482
LIG_FHA_1	51	57	PF00498	0.425
LIG_FHA_1	86	92	PF00498	0.431

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKW4	Leptomonas seymouri	72%	100%
A0A0S4JIM1	Bodo saltans	38%	100%
A0A1X0P3L7	Trypanosomatidae	40%	100%
A0A3S7XBF2	Leishmania donovani	93%	100%
A0A422NKK4	Trypanosoma rangeli	40%	100%
A4HPR0	Leishmania braziliensis	87%	100%
A4ID04	Leishmania infantum	93%	100%
D0A8F5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	93%
Q4Q123	Leishmania major	93%	100%

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