Similar to leishmania major. l411.4-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:

Gene product:

similar to leishmania major. l411.4-like protein

Species:

Leishmania mexicana

UniProt:

E9ATG8_LEIMU

TriTrypDb:

LmxM.36.3860

Length:

293

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0005886	plasma membrane	3	2
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9ATG8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATG8

Function

Biological processes
Term	Name	Level	Count
GO:0007338	single fertilization	3	2
GO:0009566	fertilization	2	2
GO:0022414	reproductive process	1	2

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0008289	lipid binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	238	240	PF00675	0.650
CLV_PCSK_KEX2_1	238	240	PF00082	0.650
CLV_PCSK_SKI1_1	168	172	PF00082	0.650
CLV_PCSK_SKI1_1	239	243	PF00082	0.650
CLV_PCSK_SKI1_1	246	250	PF00082	0.562
DEG_Nend_Nbox_1	1	3	PF02207	0.449
DEG_SPOP_SBC_1	175	179	PF00917	0.449
DOC_CKS1_1	224	229	PF01111	0.449
DOC_PP1_RVXF_1	277	283	PF00149	0.674
DOC_PP2B_LxvP_1	3	6	PF13499	0.449
DOC_USP7_MATH_1	152	156	PF00917	0.449
DOC_USP7_MATH_1	175	179	PF00917	0.449
DOC_USP7_MATH_1	6	10	PF00917	0.449
DOC_WW_Pin1_4	18	23	PF00397	0.449
DOC_WW_Pin1_4	220	225	PF00397	0.449
LIG_14-3-3_CanoR_1	133	139	PF00244	0.449
LIG_14-3-3_CanoR_1	239	249	PF00244	0.449
LIG_14-3-3_CanoR_1	64	73	PF00244	0.449
LIG_14-3-3_CanoR_1	97	101	PF00244	0.449
LIG_Actin_WH2_2	81	99	PF00022	0.449
LIG_APCC_ABBA_1	200	205	PF00400	0.449
LIG_deltaCOP1_diTrp_1	254	260	PF00928	0.449
LIG_FHA_1	123	129	PF00498	0.449
LIG_FHA_1	167	173	PF00498	0.449
LIG_FHA_1	175	181	PF00498	0.350
LIG_FHA_2	249	255	PF00498	0.449
LIG_LIR_Gen_1	254	263	PF02991	0.449
LIG_LIR_Nem_3	137	141	PF02991	0.449
LIG_LIR_Nem_3	23	28	PF02991	0.449
LIG_LIR_Nem_3	254	258	PF02991	0.551
LIG_SH2_CRK	138	142	PF00017	0.449
LIG_SH2_CRK	272	276	PF00017	0.549
LIG_SH2_PTP2	129	132	PF00017	0.449
LIG_SH2_PTP2	143	146	PF00017	0.274
LIG_SH2_STAP1	272	276	PF00017	0.549
LIG_SH2_STAT5	129	132	PF00017	0.449
LIG_SH2_STAT5	143	146	PF00017	0.274
LIG_SH2_STAT5	24	27	PF00017	0.449
LIG_SH2_STAT5	65	68	PF00017	0.449
LIG_SH3_3	183	189	PF00018	0.449
LIG_SH3_3	221	227	PF00018	0.449
LIG_SUMO_SIM_par_1	6	11	PF11976	0.449
LIG_TRAF2_1	189	192	PF00917	0.449
LIG_TYR_ITIM	127	132	PF00017	0.449
LIG_TYR_ITIM	141	146	PF00017	0.274
LIG_TYR_ITIM	275	280	PF00017	0.666
LIG_WRC_WIRS_1	70	75	PF05994	0.449
MOD_CK1_1	195	201	PF00069	0.449
MOD_CK1_1	27	33	PF00069	0.449
MOD_CK1_1	69	75	PF00069	0.449
MOD_CK2_1	248	254	PF00069	0.449
MOD_GlcNHglycan	10	13	PF01048	0.650
MOD_GlcNHglycan	29	32	PF01048	0.412
MOD_GSK3_1	152	159	PF00069	0.449
MOD_GSK3_1	210	217	PF00069	0.449
MOD_GSK3_1	65	72	PF00069	0.449
MOD_N-GLC_1	134	139	PF02516	0.650
MOD_N-GLC_1	175	180	PF02516	0.650
MOD_N-GLC_1	214	219	PF02516	0.650
MOD_N-GLC_2	13	15	PF02516	0.650
MOD_NEK2_1	121	126	PF00069	0.449
MOD_NEK2_1	128	133	PF00069	0.362
MOD_NEK2_1	181	186	PF00069	0.449
MOD_NEK2_1	210	215	PF00069	0.449
MOD_NEK2_1	248	253	PF00069	0.449
MOD_NEK2_1	258	263	PF00069	0.375
MOD_NEK2_1	96	101	PF00069	0.449
MOD_OFUCOSY	34	41	PF10250	0.650
MOD_PIKK_1	29	35	PF00454	0.449
MOD_PKA_2	152	158	PF00069	0.449
MOD_PKA_2	96	102	PF00069	0.449
MOD_Plk_1	134	140	PF00069	0.449
MOD_Plk_1	175	181	PF00069	0.449
MOD_Plk_1	214	220	PF00069	0.449
MOD_Plk_4	176	182	PF00069	0.449
MOD_ProDKin_1	18	24	PF00069	0.449
MOD_ProDKin_1	220	226	PF00069	0.449
MOD_SUMO_for_1	232	235	PF00179	0.449
TRG_DiLeu_BaEn_1	254	259	PF01217	0.548
TRG_DiLeu_BaEn_1	80	85	PF01217	0.449
TRG_ENDOCYTIC_2	129	132	PF00928	0.449
TRG_ENDOCYTIC_2	138	141	PF00928	0.337
TRG_ENDOCYTIC_2	143	146	PF00928	0.274
TRG_ENDOCYTIC_2	272	275	PF00928	0.549
TRG_ENDOCYTIC_2	277	280	PF00928	0.583
TRG_ER_diArg_1	75	78	PF00400	0.449