NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATE5_LEIMU

TriTrypDb:

LmxM.36.3653

Length:

197

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATE5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATE5

PDB structure(s): 7aih_Z , 7am2_Z , 7ane_Z

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	182	186	PF00656	0.623
CLV_NRD_NRD_1	161	163	PF00675	0.517
CLV_NRD_NRD_1	7	9	PF00675	0.561
CLV_NRD_NRD_1	79	81	PF00675	0.594
CLV_PCSK_KEX2_1	191	193	PF00082	0.493
CLV_PCSK_KEX2_1	7	9	PF00082	0.585
CLV_PCSK_KEX2_1	79	81	PF00082	0.525
CLV_PCSK_PC1ET2_1	191	193	PF00082	0.497
CLV_PCSK_PC7_1	75	81	PF00082	0.510
CLV_PCSK_SKI1_1	191	195	PF00082	0.483
CLV_PCSK_SKI1_1	40	44	PF00082	0.650
CLV_PCSK_SKI1_1	8	12	PF00082	0.717
CLV_Separin_Metazoa	84	88	PF03568	0.555
DEG_Nend_Nbox_1	1	3	PF02207	0.617
DOC_CYCLIN_yClb1_LxF_4	101	106	PF00134	0.555
DOC_MAPK_gen_1	150	159	PF00069	0.501
DOC_MAPK_MEF2A_6	150	159	PF00069	0.524
DOC_PP1_RVXF_1	101	107	PF00149	0.455
DOC_PP1_RVXF_1	189	196	PF00149	0.470
DOC_PP4_FxxP_1	141	144	PF00568	0.508
DOC_PP4_FxxP_1	20	23	PF00568	0.533
DOC_USP7_MATH_1	112	116	PF00917	0.458
DOC_USP7_UBL2_3	150	154	PF12436	0.545
DOC_USP7_UBL2_3	187	191	PF12436	0.521
DOC_USP7_UBL2_3	99	103	PF12436	0.463
DOC_WW_Pin1_4	24	29	PF00397	0.482
LIG_deltaCOP1_diTrp_1	45	51	PF00928	0.508
LIG_FHA_1	37	43	PF00498	0.599
LIG_FHA_1	66	72	PF00498	0.521
LIG_FHA_2	177	183	PF00498	0.705
LIG_FHA_2	25	31	PF00498	0.498
LIG_HP1_1	155	159	PF01393	0.494
LIG_LIR_Apic_2	140	144	PF02991	0.616
LIG_LIR_Nem_3	151	156	PF02991	0.574
LIG_PCNA_yPIPBox_3	87	97	PF02747	0.548
LIG_Pex14_2	20	24	PF04695	0.536
LIG_REV1ctd_RIR_1	192	197	PF16727	0.540
LIG_SH2_PTP2	156	159	PF00017	0.490
LIG_SH2_STAT5	105	108	PF00017	0.480
LIG_SH2_STAT5	119	122	PF00017	0.357
LIG_SH2_STAT5	156	159	PF00017	0.474
LIG_SH3_3	108	114	PF00018	0.470
LIG_SH3_4	187	194	PF00018	0.502
LIG_TRAF2_1	158	161	PF00917	0.516
LIG_UBA3_1	164	172	PF00899	0.705
LIG_UBA3_1	189	197	PF00899	0.584
LIG_WRPW_2	153	156	PF00400	0.507
MOD_CK1_1	180	186	PF00069	0.630
MOD_CK2_1	176	182	PF00069	0.714
MOD_CMANNOS	48	51	PF00535	0.424
MOD_GlcNHglycan	179	182	PF01048	0.600
MOD_GlcNHglycan	99	102	PF01048	0.453
MOD_GSK3_1	172	179	PF00069	0.685
MOD_GSK3_1	65	72	PF00069	0.495
MOD_N-GLC_1	65	70	PF02516	0.547
MOD_NEK2_1	1	6	PF00069	0.609
MOD_NEK2_1	36	41	PF00069	0.598
MOD_NEK2_1	65	70	PF00069	0.497
MOD_PK_1	172	178	PF00069	0.567
MOD_Plk_1	148	154	PF00069	0.619
MOD_Plk_1	172	178	PF00069	0.651
MOD_Plk_4	13	19	PF00069	0.557
MOD_Plk_4	172	178	PF00069	0.567
MOD_ProDKin_1	24	30	PF00069	0.479
MOD_SUMO_rev_2	180	189	PF00179	0.612
TRG_ENDOCYTIC_2	156	159	PF00928	0.474
TRG_ER_diArg_1	33	36	PF00400	0.658
TRG_ER_diArg_1	6	8	PF00400	0.592
TRG_ER_diArg_1	78	80	PF00400	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4T5	Leptomonas seymouri	87%	99%
A0A0S4J3L6	Bodo saltans	67%	96%
A0A1X0P3A9	Trypanosomatidae	72%	100%
A0A3Q8IP77	Leishmania donovani	95%	99%
A0A422MY87	Trypanosoma rangeli	68%	97%
A4ID33	Leishmania infantum	94%	99%
D0A8I6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	100%
E9AIX9	Leishmania braziliensis	93%	100%
Q4Q152	Leishmania major	94%	100%