Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ATD0_LEIMU

TriTrypDb:

LmxM.36.3510

Length:

166

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ATD0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATD0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	81	83	PF00675	0.515
CLV_PCSK_KEX2_1	102	104	PF00082	0.637
CLV_PCSK_KEX2_1	129	131	PF00082	0.481
CLV_PCSK_KEX2_1	41	43	PF00082	0.425
CLV_PCSK_PC1ET2_1	102	104	PF00082	0.585
CLV_PCSK_PC1ET2_1	129	131	PF00082	0.481
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.425
DEG_Nend_Nbox_1	1	3	PF02207	0.504
DOC_MAPK_gen_1	129	137	PF00069	0.460
DOC_MAPK_MEF2A_6	129	137	PF00069	0.476
DOC_MAPK_NFAT4_5	130	138	PF00069	0.458
DOC_PIKK_1	62	70	PF02985	0.450
DOC_PP2B_LxvP_1	158	161	PF13499	0.646
DOC_PP2B_PxIxI_1	31	37	PF00149	0.450
DOC_USP7_MATH_1	12	16	PF00917	0.616
DOC_USP7_MATH_1	143	147	PF00917	0.553
DOC_USP7_UBL2_3	41	45	PF12436	0.477
DOC_WW_Pin1_4	149	154	PF00397	0.532
LIG_14-3-3_CanoR_1	130	134	PF00244	0.466
LIG_14-3-3_CanoR_1	48	54	PF00244	0.456
LIG_14-3-3_CanoR_1	92	98	PF00244	0.518
LIG_Actin_WH2_2	120	136	PF00022	0.421
LIG_EVH1_1	158	162	PF00568	0.564
LIG_FHA_1	23	29	PF00498	0.559
LIG_FHA_1	48	54	PF00498	0.495
LIG_FHA_1	86	92	PF00498	0.465
LIG_FHA_2	25	31	PF00498	0.513
LIG_LIR_Nem_3	114	120	PF02991	0.623
LIG_PCNA_yPIPBox_3	103	117	PF02747	0.533
LIG_SH2_SRC	73	76	PF00017	0.403
LIG_SH2_STAT5	73	76	PF00017	0.441
LIG_SH3_1	156	162	PF00018	0.568
LIG_SH3_3	147	153	PF00018	0.649
LIG_SH3_3	154	160	PF00018	0.577
LIG_SUMO_SIM_par_1	24	31	PF11976	0.520
LIG_SUMO_SIM_par_1	73	80	PF11976	0.401
MOD_CDK_SPxxK_3	149	156	PF00069	0.529
MOD_CK1_1	76	82	PF00069	0.403
MOD_CK1_1	93	99	PF00069	0.411
MOD_CK2_1	24	30	PF00069	0.608
MOD_Cter_Amidation	100	103	PF01082	0.525
MOD_GlcNHglycan	112	116	PF01048	0.545
MOD_GlcNHglycan	14	17	PF01048	0.551
MOD_GlcNHglycan	99	102	PF01048	0.405
MOD_GSK3_1	93	100	PF00069	0.429
MOD_NEK2_1	1	6	PF00069	0.507
MOD_NEK2_1	37	42	PF00069	0.474
MOD_NEK2_1	97	102	PF00069	0.533
MOD_PKA_1	129	135	PF00069	0.424
MOD_PKA_2	129	135	PF00069	0.467
MOD_PKA_2	47	53	PF00069	0.452
MOD_PKA_2	93	99	PF00069	0.574
MOD_Plk_1	111	117	PF00069	0.495
MOD_Plk_2-3	85	91	PF00069	0.487
MOD_Plk_4	93	99	PF00069	0.530
MOD_ProDKin_1	149	155	PF00069	0.529
TRG_DiLeu_BaEn_4	62	68	PF01217	0.449
TRG_ER_diArg_1	91	94	PF00400	0.435

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBR8	Leptomonas seymouri	54%	100%
A0A1X0P3J1	Trypanosomatidae	40%	93%
A0A3S7XB75	Leishmania donovani	96%	87%
A4HPL8	Leishmania braziliensis	71%	100%
A4ID46	Leishmania infantum	96%	88%
Q4Q167	Leishmania major	93%	100%