SNF7-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

SNF7-like protein

Gene product:

Charged multivesicular body protein 3, putative

Species:

Leishmania mexicana

UniProt:

E9ATC3_LEIMU

TriTrypDb:

LmxM.36.3440

Length:

217

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0000815	ESCRT III complex	3	1
GO:0005737	cytoplasm	2	1
GO:0005768	endosome	7	1
GO:0005770	late endosome	8	1
GO:0005771	multivesicular body	9	1
GO:0016020	membrane	2	2
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0032991	protein-containing complex	1	1
GO:0036452	ESCRT complex	2	1

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Expansion

Sequence features

E9ATC3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ATC3

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	12
GO:0007034	vacuolar transport	4	12
GO:0008104	protein localization	4	1
GO:0009987	cellular process	1	12
GO:0015031	protein transport	4	1
GO:0016192	vesicle-mediated transport	4	1
GO:0016197	endosomal transport	4	1
GO:0032509	endosome transport via multivesicular body sorting pathway	5	1
GO:0033036	macromolecule localization	2	1
GO:0045184	establishment of protein localization	3	1

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	28	30	PF00675	0.262
CLV_NRD_NRD_1	39	41	PF00675	0.350
CLV_NRD_NRD_1	71	73	PF00675	0.287
CLV_PCSK_KEX2_1	39	41	PF00082	0.385
DOC_MAPK_gen_1	29	35	PF00069	0.282
DOC_MAPK_gen_1	37	47	PF00069	0.234
DOC_MAPK_MEF2A_6	40	49	PF00069	0.338
DOC_USP7_UBL2_3	46	50	PF12436	0.265
DOC_WW_Pin1_4	9	14	PF00397	0.492
LIG_14-3-3_CanoR_1	22	31	PF00244	0.258

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL91	Leptomonas seymouri	79%	100%
A0A0S4JKU7	Bodo saltans	54%	83%
A0A0S4JP11	Bodo saltans	33%	99%
A0A1X0P3A0	Trypanosomatidae	64%	100%
A0A1X0P5N6	Trypanosomatidae	33%	100%
A0A381ML17	Leishmania infantum	32%	100%
A0A3R7RGQ9	Trypanosoma rangeli	56%	100%
A0A3S5H7H9	Leishmania donovani	32%	100%
A0A3S7XBB5	Leishmania donovani	96%	100%
A4HFS1	Leishmania braziliensis	33%	100%

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