| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 1 |
| Forrest at al. (metacyclic) | no | yes: 1 |
| Forrest at al. (procyclic) | no | yes: 1 |
| Silverman et al. | no | yes: 1 |
| Pissara et al. | yes | yes: 5 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 3 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 3 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 12 |
| NetGPI | no | yes: 0, no: 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0016281 | eukaryotic translation initiation factor 4F complex | 2 | 1 |
| GO:0032991 | protein-containing complex | 1 | 1 |
| GO:0097542 | ciliary tip | 2 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
Related structures:
AlphaFold database: E9AT99
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006810 | transport | 3 | 1 |
| GO:0006897 | endocytosis | 5 | 1 |
| GO:0007088 | regulation of mitotic nuclear division | 6 | 1 |
| GO:0007165 | signal transduction | 2 | 1 |
| GO:0007346 | regulation of mitotic cell cycle | 5 | 1 |
| GO:0008104 | protein localization | 4 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0010564 | regulation of cell cycle process | 5 | 1 |
| GO:0010639 | negative regulation of organelle organization | 6 | 1 |
| GO:0010948 | negative regulation of cell cycle process | 6 | 1 |
| GO:0016192 | vesicle-mediated transport | 4 | 1 |
| GO:0033036 | macromolecule localization | 2 | 1 |
| GO:0033043 | regulation of organelle organization | 5 | 1 |
| GO:0045786 | negative regulation of cell cycle | 5 | 1 |
| GO:0045839 | negative regulation of mitotic nuclear division | 7 | 1 |
| GO:0045930 | negative regulation of mitotic cell cycle | 6 | 1 |
| GO:0048519 | negative regulation of biological process | 3 | 1 |
| GO:0048523 | negative regulation of cellular process | 4 | 1 |
| GO:0050789 | regulation of biological process | 2 | 1 |
| GO:0050794 | regulation of cellular process | 3 | 1 |
| GO:0051128 | regulation of cellular component organization | 4 | 1 |
| GO:0051129 | negative regulation of cellular component organization | 5 | 1 |
| GO:0051179 | localization | 1 | 1 |
| GO:0051234 | establishment of localization | 2 | 1 |
| GO:0051641 | cellular localization | 2 | 1 |
| GO:0051726 | regulation of cell cycle | 4 | 1 |
| GO:0051783 | regulation of nuclear division | 6 | 1 |
| GO:0051784 | negative regulation of nuclear division | 7 | 1 |
| GO:0065007 | biological regulation | 1 | 1 |
| GO:0070727 | cellular macromolecule localization | 3 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 161 | 165 | PF00656 | 0.450 |
| CLV_NRD_NRD_1 | 111 | 113 | PF00675 | 0.352 |
| CLV_NRD_NRD_1 | 52 | 54 | PF00675 | 0.351 |
| CLV_NRD_NRD_1 | 81 | 83 | PF00675 | 0.337 |
| CLV_PCSK_KEX2_1 | 111 | 113 | PF00082 | 0.378 |
| CLV_PCSK_KEX2_1 | 81 | 83 | PF00082 | 0.337 |
| CLV_PCSK_SKI1_1 | 67 | 71 | PF00082 | 0.420 |
| CLV_PCSK_SKI1_1 | 86 | 90 | PF00082 | 0.366 |
| DEG_APCC_KENBOX_2 | 97 | 101 | PF00400 | 0.454 |
| DEG_ODPH_VHL_1 | 185 | 197 | PF01847 | 0.384 |
| DOC_CKS1_1 | 77 | 82 | PF01111 | 0.465 |
| DOC_MAPK_gen_1 | 244 | 252 | PF00069 | 0.366 |
| DOC_MAPK_MEF2A_6 | 192 | 199 | PF00069 | 0.338 |
| DOC_MAPK_MEF2A_6 | 44 | 52 | PF00069 | 0.351 |
| DOC_MAPK_NFAT4_5 | 192 | 200 | PF00069 | 0.337 |
| DOC_USP7_MATH_1 | 18 | 22 | PF00917 | 0.594 |
| DOC_USP7_MATH_1 | 181 | 185 | PF00917 | 0.351 |
| DOC_USP7_UBL2_3 | 208 | 212 | PF12436 | 0.326 |
| DOC_WW_Pin1_4 | 116 | 121 | PF00397 | 0.459 |
| DOC_WW_Pin1_4 | 76 | 81 | PF00397 | 0.465 |
| LIG_14-3-3_CanoR_1 | 67 | 73 | PF00244 | 0.344 |
| LIG_FHA_1 | 129 | 135 | PF00498 | 0.366 |
| LIG_FHA_1 | 186 | 192 | PF00498 | 0.337 |
| LIG_FHA_2 | 224 | 230 | PF00498 | 0.354 |
| LIG_FHA_2 | 87 | 93 | PF00498 | 0.366 |
| LIG_GBD_Chelix_1 | 242 | 250 | PF00786 | 0.351 |
| LIG_LIR_Apic_2 | 130 | 135 | PF02991 | 0.337 |
| LIG_LIR_Gen_1 | 43 | 52 | PF02991 | 0.337 |
| LIG_LIR_Nem_3 | 152 | 156 | PF02991 | 0.337 |
| LIG_LIR_Nem_3 | 200 | 206 | PF02991 | 0.337 |
| LIG_LIR_Nem_3 | 4 | 10 | PF02991 | 0.685 |
| LIG_LIR_Nem_3 | 71 | 77 | PF02991 | 0.337 |
| LIG_LYPXL_SIV_4 | 220 | 228 | PF13949 | 0.351 |
| LIG_NRBOX | 124 | 130 | PF00104 | 0.351 |
| LIG_PDZ_Class_3 | 253 | 258 | PF00595 | 0.601 |
| LIG_SH2_CRK | 74 | 78 | PF00017 | 0.337 |
| LIG_SH2_NCK_1 | 157 | 161 | PF00017 | 0.351 |
| LIG_SH2_PTP2 | 55 | 58 | PF00017 | 0.465 |
| LIG_SH2_SRC | 132 | 135 | PF00017 | 0.337 |
| LIG_SH2_SRC | 157 | 160 | PF00017 | 0.351 |
| LIG_SH2_SRC | 221 | 224 | PF00017 | 0.351 |
| LIG_SH2_STAP1 | 221 | 225 | PF00017 | 0.351 |
| LIG_SH2_STAT5 | 132 | 135 | PF00017 | 0.337 |
| LIG_SH2_STAT5 | 146 | 149 | PF00017 | 0.337 |
| LIG_SH2_STAT5 | 55 | 58 | PF00017 | 0.465 |
| LIG_SH3_2 | 187 | 192 | PF14604 | 0.366 |
| LIG_SH3_3 | 14 | 20 | PF00018 | 0.607 |
| LIG_SH3_3 | 184 | 190 | PF00018 | 0.366 |
| LIG_SH3_3 | 74 | 80 | PF00018 | 0.465 |
| LIG_SUMO_SIM_anti_2 | 123 | 131 | PF11976 | 0.351 |
| LIG_SUMO_SIM_par_1 | 123 | 131 | PF11976 | 0.351 |
| LIG_TYR_ITIM | 201 | 206 | PF00017 | 0.314 |
| LIG_TYR_ITIM | 72 | 77 | PF00017 | 0.406 |
| LIG_UBA3_1 | 32 | 37 | PF00899 | 0.513 |
| LIG_UBA3_1 | 48 | 54 | PF00899 | 0.329 |
| MOD_CDK_SPK_2 | 76 | 81 | PF00069 | 0.465 |
| MOD_CDK_SPxK_1 | 76 | 82 | PF00069 | 0.465 |
| MOD_CK1_1 | 90 | 96 | PF00069 | 0.343 |
| MOD_CK2_1 | 223 | 229 | PF00069 | 0.351 |
| MOD_CK2_1 | 86 | 92 | PF00069 | 0.351 |
| MOD_GlcNHglycan | 161 | 164 | PF01048 | 0.419 |
| MOD_GlcNHglycan | 99 | 103 | PF01048 | 0.428 |
| MOD_GSK3_1 | 124 | 131 | PF00069 | 0.431 |
| MOD_GSK3_1 | 181 | 188 | PF00069 | 0.342 |
| MOD_GSK3_1 | 223 | 230 | PF00069 | 0.351 |
| MOD_GSK3_1 | 57 | 64 | PF00069 | 0.366 |
| MOD_GSK3_1 | 86 | 93 | PF00069 | 0.343 |
| MOD_N-GLC_1 | 181 | 186 | PF02516 | 0.348 |
| MOD_N-GLC_1 | 197 | 202 | PF02516 | 0.298 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.620 |
| MOD_NEK2_1 | 128 | 133 | PF00069 | 0.366 |
| MOD_NEK2_1 | 197 | 202 | PF00069 | 0.343 |
| MOD_Plk_1 | 181 | 187 | PF00069 | 0.348 |
| MOD_Plk_1 | 197 | 203 | PF00069 | 0.298 |
| MOD_Plk_2-3 | 124 | 130 | PF00069 | 0.432 |
| MOD_Plk_2-3 | 223 | 229 | PF00069 | 0.351 |
| MOD_Plk_2-3 | 61 | 67 | PF00069 | 0.351 |
| MOD_Plk_4 | 124 | 130 | PF00069 | 0.377 |
| MOD_Plk_4 | 238 | 244 | PF00069 | 0.465 |
| MOD_ProDKin_1 | 116 | 122 | PF00069 | 0.459 |
| MOD_ProDKin_1 | 76 | 82 | PF00069 | 0.465 |
| MOD_SUMO_rev_2 | 21 | 26 | PF00179 | 0.487 |
| TRG_DiLeu_BaEn_1 | 65 | 70 | PF01217 | 0.337 |
| TRG_DiLeu_BaEn_4 | 65 | 71 | PF01217 | 0.337 |
| TRG_DiLeu_BaLyEn_6 | 241 | 246 | PF01217 | 0.366 |
| TRG_ENDOCYTIC_2 | 146 | 149 | PF00928 | 0.344 |
| TRG_ENDOCYTIC_2 | 157 | 160 | PF00928 | 0.323 |
| TRG_ENDOCYTIC_2 | 203 | 206 | PF00928 | 0.336 |
| TRG_ENDOCYTIC_2 | 55 | 58 | PF00928 | 0.400 |
| TRG_ENDOCYTIC_2 | 74 | 77 | PF00928 | 0.337 |
| TRG_ER_diArg_1 | 110 | 112 | PF00400 | 0.386 |
| TRG_ER_diArg_1 | 80 | 82 | PF00400 | 0.465 |
| TRG_NES_CRM1_1 | 46 | 61 | PF08389 | 0.351 |
| TRG_Pf-PMV_PEXEL_1 | 112 | 117 | PF00026 | 0.408 |
| TRG_Pf-PMV_PEXEL_1 | 244 | 248 | PF00026 | 0.366 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P443 | Leptomonas seymouri | 51% | 100% |
| A0A0N1IJ96 | Leptomonas seymouri | 95% | 100% |
| A0A0S4IUJ3 | Bodo saltans | 57% | 93% |
| A0A0S4JJB7 | Bodo saltans | 72% | 99% |
| A0A1X0NVF8 | Trypanosomatidae | 53% | 100% |
| A0A1X0P3Q3 | Trypanosomatidae | 80% | 98% |
| A0A3R7KVM5 | Trypanosoma rangeli | 52% | 100% |
| A0A3S7WRH0 | Leishmania donovani | 52% | 100% |
| A0A3S7XB66 | Leishmania donovani | 100% | 100% |
| A0A422NKL2 | Trypanosoma rangeli | 78% | 98% |
| A4H6F2 | Leishmania braziliensis | 52% | 100% |
| A4HPI7 | Leishmania braziliensis | 95% | 100% |
| A4HUU6 | Leishmania infantum | 52% | 100% |
| A4IDA9 | Leishmania infantum | 99% | 100% |
| A4K2U9 | Pongo abelii | 52% | 100% |
| B8NLM9 | Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) | 54% | 100% |
| C0H4V6 | Plasmodium falciparum (isolate 3D7) | 47% | 98% |
| D0A7L0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 54% | 100% |
| D0A8F0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 76% | 98% |
| E2RU97 | Giardia intestinalis (strain ATCC 50803 / WB clone C6) | 50% | 100% |
| E9ANI1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 52% | 100% |
| O42766 | Candida albicans (strain SC5314 / ATCC MYA-2876) | 53% | 98% |
| O49995 | Nicotiana tabacum | 55% | 100% |
| O49996 | Nicotiana tabacum | 52% | 100% |
| O49997 | Nicotiana tabacum | 55% | 95% |
| O49998 | Nicotiana tabacum | 54% | 100% |
| O65352 | Helianthus annuus | 54% | 100% |
| O70456 | Mus musculus | 50% | 100% |
| O77642 | Ovis aries | 50% | 100% |
| O96436 | Eimeria tenella | 45% | 93% |
| P27348 | Homo sapiens | 53% | 100% |
| P29305 | Hordeum vulgare | 54% | 98% |
| P29307 | Oenothera elata subsp. hookeri | 53% | 99% |
| P29308 | Spinacia oleracea | 56% | 100% |
| P29309 | Xenopus laevis | 51% | 100% |
| P29310 | Drosophila melanogaster | 51% | 100% |
| P29311 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 54% | 97% |
| P29361 | Ovis aries | 51% | 100% |
| P31946 | Homo sapiens | 52% | 100% |
| P31947 | Homo sapiens | 50% | 100% |
| P34730 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 54% | 95% |
| P35213 | Rattus norvegicus | 52% | 100% |
| P41932 | Caenorhabditis elegans | 52% | 100% |
| P42643 | Arabidopsis thaliana | 57% | 97% |
| P42644 | Arabidopsis thaliana | 54% | 100% |
| P42645 | Arabidopsis thaliana | 53% | 96% |
| P42648 | Entamoeba histolytica | 49% | 100% |
| P42649 | Entamoeba histolytica | 49% | 100% |
| P42650 | Entamoeba histolytica | 51% | 100% |
| P42652 | Solanum lycopersicum | 54% | 99% |
| P42653 | Vicia faba | 54% | 99% |
| P42654 | Vicia faba | 51% | 99% |
| P42656 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 51% | 96% |
| P42657 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 52% | 96% |
| P46077 | Arabidopsis thaliana | 55% | 97% |
| P46266 | Pisum sativum | 56% | 99% |
| P48347 | Arabidopsis thaliana | 51% | 100% |
| P48348 | Arabidopsis thaliana | 55% | 100% |
| P48349 | Arabidopsis thaliana | 54% | 100% |
| P49106 | Zea mays | 53% | 99% |
| P52908 | Chlamydomonas reinhardtii | 56% | 100% |
| P54632 | Dictyostelium discoideum | 51% | 100% |
| P61981 | Homo sapiens | 49% | 100% |
| P61982 | Mus musculus | 49% | 100% |
| P61983 | Rattus norvegicus | 49% | 100% |
| P62258 | Homo sapiens | 54% | 100% |
| P62259 | Mus musculus | 54% | 100% |
| P62260 | Rattus norvegicus | 54% | 100% |
| P62261 | Bos taurus | 54% | 100% |
| P62262 | Ovis aries | 54% | 100% |
| P63101 | Mus musculus | 51% | 100% |
| P63102 | Rattus norvegicus | 51% | 100% |
| P63103 | Bos taurus | 51% | 100% |
| P63104 | Homo sapiens | 51% | 100% |
| P68250 | Bos taurus | 52% | 100% |
| P68251 | Ovis aries | 41% | 100% |
| P68252 | Bos taurus | 49% | 100% |
| P68254 | Mus musculus | 53% | 100% |
| P68255 | Rattus norvegicus | 53% | 100% |
| P68509 | Bos taurus | 50% | 100% |
| P68510 | Mus musculus | 50% | 100% |
| P68511 | Rattus norvegicus | 50% | 100% |
| P92177 | Drosophila melanogaster | 54% | 98% |
| P93206 | Solanum lycopersicum | 53% | 100% |
| P93207 | Solanum lycopersicum | 51% | 100% |
| P93208 | Solanum lycopersicum | 56% | 100% |
| P93209 | Solanum lycopersicum | 54% | 99% |
| P93210 | Solanum lycopersicum | 54% | 100% |
| P93211 | Solanum lycopersicum | 54% | 100% |
| P93212 | Solanum lycopersicum | 51% | 100% |
| P93213 | Solanum lycopersicum | 50% | 99% |
| P93214 | Solanum lycopersicum | 50% | 99% |
| P93259 | Mesembryanthemum crystallinum | 55% | 98% |
| P93342 | Nicotiana tabacum | 53% | 100% |
| P93343 | Nicotiana tabacum | 55% | 99% |
| P93784 | Solanum tuberosum | 54% | 100% |
| Q01525 | Arabidopsis thaliana | 56% | 100% |
| Q01526 | Zea mays | 52% | 99% |
| Q04917 | Homo sapiens | 50% | 100% |
| Q06967 | Oryza sativa subsp. japonica | 54% | 99% |
| Q0VC36 | Bos taurus | 50% | 100% |
| Q1HR36 | Aedes aegypti | 50% | 100% |
| Q20655 | Caenorhabditis elegans | 51% | 100% |
| Q24902 | Echinococcus multilocularis | 46% | 100% |
| Q25538 | Neospora caninum | 46% | 97% |
| Q26537 | Schistosoma mansoni | 52% | 100% |
| Q26540 | Schistosoma mansoni | 48% | 100% |
| Q2F637 | Bombyx mori | 50% | 100% |
| Q2R1D5 | Oryza sativa subsp. japonica | 35% | 100% |
| Q2R2W2 | Oryza sativa subsp. japonica | 54% | 97% |
| Q39757 | Fucus vesiculosus | 53% | 100% |
| Q3SZI4 | Bos taurus | 53% | 100% |
| Q41246 | Nicotiana tabacum | 49% | 100% |
| Q41418 | Solanum tuberosum | 53% | 100% |
| Q43470 | Hordeum vulgare | 52% | 98% |
| Q43643 | Solanum tuberosum | 53% | 100% |
| Q4Q198 | Leishmania major | 99% | 100% |
| Q4QH45 | Leishmania major | 52% | 100% |
| Q4R572 | Macaca fascicularis | 52% | 100% |
| Q52M98 | Xenopus laevis | 53% | 100% |
| Q5F3W6 | Gallus gallus | 49% | 100% |
| Q5PRD0 | Danio rerio | 51% | 100% |
| Q5QNB8 | Oryza sativa subsp. japonica | 50% | 100% |
| Q5R651 | Pongo abelii | 51% | 100% |
| Q5RC20 | Pongo abelii | 49% | 100% |
| Q5RFJ2 | Pongo abelii | 53% | 100% |
| Q5XGC8 | Xenopus tropicalis | 51% | 100% |
| Q5XHK2 | Xenopus laevis | 51% | 100% |
| Q5ZKC9 | Gallus gallus | 51% | 100% |
| Q5ZLQ6 | Gallus gallus | 52% | 100% |
| Q5ZMD1 | Gallus gallus | 52% | 100% |
| Q5ZMT0 | Gallus gallus | 54% | 100% |
| Q6EUP4 | Oryza sativa subsp. japonica | 53% | 98% |
| Q6NRY9 | Xenopus laevis | 48% | 100% |
| Q6P4Z5 | Xenopus tropicalis | 52% | 100% |
| Q6PC29 | Danio rerio | 48% | 100% |
| Q6PCG0 | Xenopus laevis | 49% | 100% |
| Q6Q6X0 | Oryctolagus cuniculus | 53% | 100% |
| Q6UFZ2 | Oncorhynchus mykiss | 49% | 100% |
| Q6UFZ3 | Oncorhynchus mykiss | 48% | 100% |
| Q6UFZ8 | Oncorhynchus mykiss | 49% | 100% |
| Q6UFZ9 | Oncorhynchus mykiss | 51% | 100% |
| Q6ZKC0 | Oryza sativa subsp. japonica | 54% | 100% |
| Q7T356 | Danio rerio | 50% | 100% |
| Q7XTE8 | Oryza sativa subsp. japonica | 52% | 98% |
| Q84J55 | Oryza sativa subsp. japonica | 54% | 98% |
| Q8AVQ3 | Xenopus laevis | 51% | 100% |
| Q8MM75 | Echinococcus multilocularis | 49% | 100% |
| Q8MUA4 | Echinococcus granulosus | 49% | 100% |
| Q8SW28 | Encephalitozoon cuniculi (strain GB-M1) | 42% | 100% |
| Q91896 | Xenopus laevis | 51% | 100% |
| Q96299 | Arabidopsis thaliana | 53% | 98% |
| Q96300 | Arabidopsis thaliana | 54% | 97% |
| Q96450 | Glycine max | 53% | 100% |
| Q96451 | Glycine max | 51% | 100% |
| Q96452 | Glycine max | 53% | 100% |
| Q96453 | Glycine max | 52% | 99% |
| Q99002 | Trichoderma harzianum | 53% | 98% |
| Q9C5W6 | Arabidopsis thaliana | 54% | 96% |
| Q9CQV8 | Mus musculus | 51% | 100% |
| Q9S9Z8 | Arabidopsis thaliana | 50% | 100% |
| Q9SP07 | Lilium longiflorum | 55% | 100% |
| Q9U408 | Echinococcus granulosus | 45% | 100% |
| V5B9L7 | Trypanosoma cruzi | 78% | 98% |
| V5C116 | Trypanosoma cruzi | 53% | 100% |