LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

DUF4164 family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF4164 family protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AT62_LEIMU
TriTrypDb:
LmxM.36.2845
Length:
92

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AT62
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AT62

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_SPOP_SBC_1 66 70 PF00917 0.447
DOC_USP7_UBL2_3 55 59 PF12436 0.680
LIG_14-3-3_CanoR_1 61 67 PF00244 0.461
LIG_BIR_II_1 1 5 PF00653 0.553
LIG_FHA_1 41 47 PF00498 0.553
LIG_FHA_1 71 77 PF00498 0.609
LIG_FHA_2 1 7 PF00498 0.539
LIG_TRAF2_1 47 50 PF00917 0.353
MOD_CK1_1 62 68 PF00069 0.620
MOD_CK1_1 70 76 PF00069 0.637
MOD_CK2_1 44 50 PF00069 0.350
MOD_CK2_1 65 71 PF00069 0.450
MOD_GlcNHglycan 80 83 PF01048 0.594
MOD_GSK3_1 40 47 PF00069 0.370
MOD_GSK3_1 62 69 PF00069 0.589
MOD_PKA_2 60 66 PF00069 0.739
TRG_ER_diArg_1 14 17 PF00400 0.552

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I666 Leptomonas seymouri 49% 98%
A0A3Q8IG76 Leishmania donovani 88% 100%
A4HPF1 Leishmania braziliensis 77% 100%
A4ICJ2 Leishmania infantum 88% 100%
D0A3G0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 97%
Q4Q1D5 Leishmania major 90% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS